Most-read are based on citations from 2024 ~ 2026.
Statistical Review Article
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Sample size determination for conducting a pilot study to assess reliability of a questionnaire
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Mohamad Adam Bujang, Evi Diana Omar, Diana Hui Ping Foo, Yoon Khee Hon
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Restor Dent Endod 2024;49(1):e3. Published online January 10, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e3
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Abstract
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This article is a narrative review that discusses the recommended sample size requirements to design a pilot study to assess the reliability of a questionnaire. A list of various sample size tables that are based on the kappa agreement test, intra-class correlation test and Cronbach’s alpha test has been compiled together. For all calculations, type I error (alpha) was set at a maximum value of 0.05, and power was set at a minimum value of 80.0%. For the kappa agreement test, intra-class correlation test, and Cronbach’s alpha test, the recommended minimum sample size requirement based on the ideal effect sizes shall be at least 15, 22, and 24 subjects respectively. By making allowances for a non-response rate of 20.0%, a minimum sample size of 30 respondents will be sufficient to assess the reliability of the questionnaire. The clear guideline of minimum sample size requirement for the pilot study to assess the reliability of a questionnaire is discussed and this will ease researchers in preparation for the pilot study. This study provides justification for a minimum requirement of a sample size of 30 respondents specifically to test the reliability of a questionnaire.
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Luay M Mohammed , Manoochehr Karami, Yadollah Mehrabi , Seyed S Hashemi, Somayeh Farhang Dehghan, Mohammed Rafiee, Hasan Baiee
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Shozo Okochi, Kyoko Oshiro, Noriyasu Takeuchi, Mariko Miyamichi, Tomoe Nakamura, Terumi Matsushima, Masako Okada, Yoshimi Kudo, Takehiro Ishiyama, Tomoyasu Kinoshita, Hideki Kojima, Mitsunori Nishikawa
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Madi Talal Alharbi, Mahamed Ateef, Ahmad Alanazi, Msaad Alzhrani
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Dilek Demir Kösem, Şenay Demir, Murat Bektaş, Frances DiAnna Kinder
Journal of Pediatric Nursing.2024; 78: e75. CrossRef - Advanced Work Packaging (AWP): Implementation and Challenges in the Malaysian Oil and Gas Sector
Muhammad Ali Musarat, Wesam Salah Alaloul, Mohd Al-Azahary bin Abdullah Sani, Ng Wei Chong
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Information.2024; 15(9): 570. CrossRef
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84
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110
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Review Articles
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Success rate of direct pulp capping on permanent teeth using bioactive materials: a systematic review and meta-analysis of randomized clinical trials
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Karem Paula Pinto, Gabriela Ribeiro da Silva, Cláudio Malizia Alves Ferreira, Luciana Moura Sassone, Emmanuel João Nogueira Leal da Silva
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Restor Dent Endod 2024;49(4):e34. Published online September 6, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e34
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Abstract
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Supplementary Material
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This systematic review and meta-analysis aimed to evaluate the success rate of direct pulp capping (DPC) on permanent teeth, comparing the use of MTA with calcium hydroxide and calcium silicate-based cements. A systematic search was carried out in 4 databases until July 2023. The selection was based on PICOS criteria and only randomized clinical trials were included. The risk of bias was assessed using RoB-2 tool, and meta-analyses were performed using RevMan 5.3 software. The overall quality of evidence was determined using the GRADE tool. Thirteen studies were included. Meta-analyses indicated significantly higher success rate for DPC using MTA compared to calcium hydroxide, while no significant difference was observed between MTA and Biodentine, showing a success rate from 80% to 100% even after 3 years of follow-up. Five studies were classified as having high risk of bias and the GRADE assessment revealed low certainty of evidence. DPC is highly effective for permanent teeth when using MTA or Biodentine. There is a need for future well-designed randomized clinical trials to evaluate the efficacy of DPC using newer bioceramic materials.
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- Physicochemical effects of nano type-B bone substitute on pulp protective cement formulations
Njwan Fadhel SHEHAB
Dental Materials Journal.2026;[Epub] CrossRef - Photobiomodulation-assisted pulp capping using nano-hydroxyapatite and mineral trioxide aggregate: Report of two cases
Priya Pal, Rhythm Bains, Promila Verma, Vivek Kumar Bains
Journal of Healthcare Research and Education.2026; 2: 2. CrossRef - Indian Association of Conservative Dentistry and Endodontics consensus statement on deep caries management
Deepak Kumar Sharma, R. S. Mohan Kumar, Shishir Singh, Suparna Ganguly Saha, Meenal Nithin Gulve, Dipali Y. Shah, Sathish Abraham, Shruthi Nagaraja, Raksha Bhat
Journal of Conservative Dentistry and Endodontics.2025; 28(8): 714. CrossRef
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17,880
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1
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3
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Cone-beam computed tomography in endodontics: from the specific technical considerations of acquisition parameters and interpretation to advanced clinical applications
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Néstor Ríos-Osorio, Sara Quijano-Guauque, Sandra Briñez-Rodríguez, Gustavo Velasco-Flechas, Antonieta Muñoz-Solís, Carlos Chávez, Rafael Fernandez-Grisales
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Restor Dent Endod 2024;49(1):e1. Published online December 11, 2023
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DOI: https://doi.org/10.5395/rde.2024.49.e1
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Abstract
PDF
PubReader
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The implementation of imaging methods that enable sensitive and specific observation of anatomical structures has been a constant in the evolution of endodontic therapy. Cone-beam computed tomography (CBCT) enables 3-dimensional (3D) spatial anatomical navigation in the 3 volumetric planes (sagittal, coronal and axial) which translates into great accuracy for the identification of endodontic pathologies/conditions. CBCT interpretation consists of 2 main components: (i) the generation of specific tasks of the image and (ii) the subsequent interpretation report. A systematic and reproducible method to review CBCT scans can improve the accuracy of the interpretation process, translating into greater precision in terms of diagnosis and planning of endodontic clinical procedures. MEDLINE (PubMed), Web of Science, Google Scholar, Embase and Scopus were searched from inception to March 2023. This narrative review addresses the theoretical concepts, elements of interpretation and applications of the CBCT scan in endodontics. In addition, the contents and rationale for reporting 3D endodontic imaging are discussed.
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Ayşe Çelik, Nilüfer Ersan, Senem Selvi-Kuvvetli
The Cleft Palate Craniofacial Journal.2025;[Epub] CrossRef - Machine Learning Models in the Detection of MB2 Canal Orifice in CBCT Images
Shishir Shetty, Meliz Yuvali, Ilker Ozsahin, Saad Al-Bayatti, Sangeetha Narasimhan, Mohammed Alsaegh, Hiba Al-Daghestani, Raghavendra Shetty, Renita Castelino, Leena R David, Dilber Uzun Ozsahin
International Dental Journal.2025; 75(3): 1640. CrossRef - Early diagnosis of acute lymphoblastic leukemia utilizing clinical, radiographic, and dental age indicators
Rehab F Ghouraba, Shaimaa S. EL-Desouky, Mohamed R. El-Shanshory, Ibrahim A. Kabbash, Nancy M. Metwally
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Nora M. Abo Shanady, Nahed A. Abo Hamila, Gamal M. El Maghraby, Rehab F. Ghouraba
BMC Oral Health.2025;[Epub] CrossRef - The Integration of Cone Beam Computed Tomography, Artificial Intelligence, Augmented Reality, and Virtual Reality in Dental Diagnostics, Surgical Planning, and Education: A Narrative Review
Aida Meto, Gerta Halilaj
Applied Sciences.2025; 15(11): 6308. CrossRef - Healing Outcomes of Through‐And‐Through Bone Defects in Periapical Surgery: A Systematic Review and Meta‐Analysis
Bibi Fatima, Farhan Raza Khan, Syeda Abeerah Tanveer
Australian Endodontic Journal.2025; 51(2): 518. CrossRef - Genotoxic and cytotoxic effects of cone beam computed tomography on exfoliated epithelial cells in different age groups
Maged Bakr, Fatma Ata, Asmaa Saleh Elmahdy, Bassant Mowafey
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Seethalakshmi Tamizhselvan, Diana Davidson, Srinivasan Manali Ramakrishnan
Journal of Conservative Dentistry and Endodontics.2025; 28(8): 833. CrossRef - IMAGING TECHNIQUES IN ENDODONTIC DIAGNOSIS: A REVIEW OF LITERATURE
Mihaela Salceanu, Anca Melian , Tudor Hamburda , Cristina Antohi , Corina Concita , Claudiu Topoliceanu , Cristian Levente Giuroiu
Romanian Journal of Oral Rehabilitation.2025; 17(1): 705. CrossRef - A Three-rooted Deciduous Second Molar in a 13-year-old Caucasian Female
Daniel Traub, Robert Walsh, Colleen Ahern
International Journal of Medical Case Reports.2025; 4(3): 51. CrossRef - Critical success factors for digital transformation in government organizations using a structural model approach
Abdalla Al Maazmi, Zehra Canan Araci, Sujan Piya
Discover Applied Sciences.2025;[Epub] CrossRef - AGE ESTIMATION BASED ON PULP / TOOTH VOLUME BY CONE BEAM COMPUTERIZED TOMOGRAPHY IMAGE
Ramadhan Rasheed, Salah Faraj
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY.2025; : 288. CrossRef - Clinical Benefits and Limitations of Cone-Beam Computed Tomography in Endodontic Practice: A Contemporary Evidence-Based Review
Jasmine Wong, Chengfei Zhang, Angeline Hui Cheng Lee
Diagnostics.2025; 15(24): 3117. CrossRef - On the Causes of Persistent Apical Periodontitis. Findings From Endodontic Microsurgery: A Case Report
Mateo José Pesántez-Ibarra, Carolina Berruecos-Orozco, Jeimmy Katherine Molina-Barrera, Néstor Ríos-Osorio, Rafael Fernández-Grisales
Journal of Endodontic Microsurgery.2025;[Epub] CrossRef - Bildgebung im ZMK-Bereich – aber in welcher Reihenfolge?
Rainer Lutz
Zahnmedizin up2date.2024; 18(04): 297. CrossRef - Cone-beam computed tomography evaluation of shaping ability of kedo-S square and fanta AF™ baby rotary files compared to manual K-files in root canal preparation of primary anterior teeth
Shaimaa S. El-Desouky, Bassem N. El Fahl, Ibrahim A. Kabbash, Shimaa M. Hadwa
Clinical Oral Investigations.2024;[Epub] CrossRef - Analysis of Endodontic Successes and Failures in the Removal of Fractured Endodontic Instruments during Retreatment: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis
Mario Dioguardi, Corrado Dello Russo, Filippo Scarano, Fariba Esperouz, Andrea Ballini, Diego Sovereto, Mario Alovisi, Angelo Martella, Lorenzo Lo Muzio
Healthcare.2024; 12(14): 1390. CrossRef
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Statistical Research Article
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An elaboration on sample size determination for correlations based on effect sizes and confidence interval width: a guide for researchers
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Mohamad Adam Bujang
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Restor Dent Endod 2024;49(2):e21. Published online May 2, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e21
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Abstract
PDF
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- Objectives
This paper aims to serve as a useful guide for sample size determination for various correlation analyses that are based on effect sizes and confidence interval width.
Materials and MethodsSample size determinations are calculated for Pearson’s correlation, Spearman’s rank correlation, and Kendall’s Tau-b correlation. Examples of sample size statements and their justification are also included.
ResultsUsing the same effect sizes, there are differences between the sample size determination of the 3 statistical tests. Based on an empirical calculation, a minimum sample size of 149 is usually adequate for performing both parametric and non-parametric correlation analysis to determine at least a moderate to an excellent degree of correlation with acceptable confidence interval width.
ConclusionsDetermining data assumption(s) is one of the challenges to offering a valid technique to estimate the required sample size for correlation analyses. Sample size tables are provided and these will help researchers to estimate a minimum sample size requirement based on correlation analyses.
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Azzam Zrineh, Maysa Al‐Usta, Abdallah Alwawi
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Mas Atikah Lizazman, Vivien Yi Mian Jong, Nor Hisam Zamakshshari, Yiizamy Suffian, Mohamad Izwan Bin Ismail, Enis Nadia Md Yusof, Nurr Maria Ulfa Binti Seruji
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Dan Hu, Yue Li, Hua Zhang, Lian-Lian Wang, Wen-Wen Liu, Xin Yang, Ming-Zhao Xiao, Hao-Ling Zhang, Juan Li
World Journal of Gastroenterology.2025;[Epub] CrossRef - Return to work in young and middle-aged colorectal cancer survivors: Factors influencing self-efficacy, fear, resilience, and financial toxicity
Dan Hu, Yue Li, Hua Zhang, Lian-Lian Wang, Wen-Wen Liu, Xin Yang, Ming-Zhao Xiao, Hao-Ling Zhang, Juan Li
World Journal of Gastroenterology.2025;[Epub] CrossRef - Predictive validity of obstacle-crossing test variations in identifying fallers after inpatient rehabilitation for stroke
Prudence Plummer, Megan E. Schliep, Lina Jallad, Ehsan Sinaei, Jody A. Feld, Vicki S. Mercer
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ACS Applied Materials & Interfaces.2025; 17(17): 25634. CrossRef - Playfulness of Preschool-Aged Children With Autism in a Sensory Integration Room
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Research Articles
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Fracture resistance and failure modes of endodontically-treated permanent teeth restored with Ribbond posts vs other post systems: a systematic review and meta-analysis of in vitro studies
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Meghana Aditya Vartak, Vibha Rahul Hegde, Sanitra Rahul Hegde, Ushaina Fanibunda
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Restor Dent Endod 2025;50(1):e5. Published online February 17, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e5
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Abstract
PDF
PubReader
ePub
- Objectives
This systematic review aimed to investigate the fracture resistance and mode of failure of endodontically-treated permanent teeth restored with Ribbond posts (Ribbond, Inc.) compared with endodontically-treated permanent teeth restored with other post systems.
Methods
A comprehensive, systematic literature search was carried out using several electronic databases: MEDLINE/PubMed, Google Scholar, and Cochrane Library. Two separate researchers were appointed to identify the studies meeting the eligibility criteria, and to perform the data extraction, risk of bias, and quality assessment.
Results
Twelve studies were included in the quantitative analysis. Meta-analysis was performed with 11 of the 12 included articles. The meta-analysis showed that Ribbond posts have a fracture strength less than prefabricated metal posts, cast metal posts, and prefabricated fiber posts and greater than custom e-glass fiber posts. Mode of failure analysis revealed that Ribbond posts have the most favorable non-catastrophic fractures.
Conclusions
Although Ribbond posts have lower fracture resistance, their favorable mode of failure makes them potentially the most biomimetic post system.
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- Effect of Short and Long Fiber-Reinforced Composite Resins Used as Post and Core on Fracture Resistance of Premolars: An in vitro Study
Manal Hussian Abd-alla, Tuqa Jameel Ebrahim, Ahmed Sleibi Mustafa
Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ).2026; 10(1): 66. CrossRef - Análise comparativa dos aspectos biomecânicos dos pinos de fibra de vidro e fibra de polietileno (RIBBOND) - revisão de literatura
Ana Kamily da Cunha Silva, Tânia Regina Carvalho de Sá, Livia Duarte Santos Lopes de Carvalho, Lilian Gomes Soares Pires, Marconi Raphael de Siqueira Rego, Matheus Araújo Brito Santos Lopes
RCMOS - Revista Científica Multidisciplinar O Saber.2025;[Epub] CrossRef - Biomimetic Strategies for the Rehabilitation of Compromised Anterior Teeth
Aakansha Puri, M.S. Prathap
Contemporary Clinical Dentistry.2025; 16(3): 218. CrossRef - Clinical Outcomes of Nonmetallic Customized Post-and-Core Systems: A Systematic Review
Jonathan Jun Xian Yuen, Yew Hin Beh, Zhi Kuan Saw, Hock Siang Chua
Journal of Endodontics.2025;[Epub] CrossRef - Evaluation of fracture resistance and crack propensity of bulk-fill composite restorations reinforced by polyethylene fiber
Ayşe Aslı Şenol, Aybike Manav, Bengü Doğu Kaya, Pınar Yılmaz Atalı, Erkut Kahramanoğlu, Bilge Tarçın, Cafer Türkmen
BMC Oral Health.2025;[Epub] CrossRef - A Comparative Study on the Fracture Resistance of CAD/CAM–Fabricated Single‐Piece Post‐Crowns
Ali Erdem, Mehmet Selim Bilgin, Ibrahim Ersoy, Erhan Dilber, Ebru Nur Işık, Tan Fırat Eyüboğlu, Mutlu Özcan
Clinical and Experimental Dental Research.2025;[Epub] CrossRef - Fracture Resistance of Extensively Compromised Anterior Teeth Restored With Fiberglass Posts and Biomimetic Protocols: An In Vitro Study
Chiu Tzyy Haur, Emanuel Ewerton Mendonça Vasconcelos, Natália Gomes de Oliveira, Gabriela Queiroz de Melo Monteiro, Luís Felipe Espíndola‐Castro
Journal of Esthetic and Restorative Dentistry.2025;[Epub] CrossRef - CAD/CAM Technologies in Post and Core Restoration of Endodontically Treated Teeth: Current Evidence, Clinical Applications, and Interdisciplinary Perspectives
Rawabi Abdulrahman Ahmed, Faris Ali Aseri, Ahmed Saleh Alammari, Zaher Saleh Asiri, Fahad Oudah Al Matir, Sami Safar Al Shahrani, Abdullah Ali Alharthi, Abdulaziz Ahmed Alfaifi, Hassan Yahya Hassan Asiri, Hassan Manea Ali Al Fotais, Amal Mali Almutairi, A
Journal of Clinical Practice and Medical Research.2025; 1(3): 178. CrossRef
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Effect of quality of radiographs taken during root canal treatment on technical quality of root canal fillings and endodontic outcome
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Jia Min Ng, Yan Yee Lee, Prashanti Chippagiri, Elaheh Ahanin, Abhishek Parolia
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Restor Dent Endod 2025;50(1):e3. Published online January 7, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e3
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Abstract
PDF
PubReader
ePub
- Objectives
This study evaluated the number and quality of working length (WL) and master cone (MC) radiographs taken during root canal treatment by dental undergraduates, and their associations with the technical quality of root canal fillings (TQRCF) and endodontic outcomes (EO).
Methods
A retrospective evaluation of radiographs from 303 root canal-treated teeth in 231 patients was conducted, with 72 patients attending recall visits to assess EO. The chi-square and one-way analysis of variance tests were performed.
Results
A total of 505 WL and 557 MC radiographs were reviewed, with 72.9% and 75% deemed satisfactory, respectively. Satisfactory TQRCF was achieved in 60.4% of cases. Significant associations were found between the extension of the file in WL and gutta-percha in MC radiographs and TQRCF (p = 0.000). Misinterpretation of these radiographs resulted in poor TQRCF. Furthermore, 64.2% of teeth had satisfactory EO. A significant relationship was noted between the quality of MC radiographs and both TQRCF (p = 0.043) and EO (p = 0.003).
Conclusions
Unsatisfactory MC radiographs were linked to poor TQRCF and unfavorable EO. Regular radiographic training is recommended to enhance EO.
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- Assessment of radiographic errors and repetition rates in undergraduate endodontic education: a retrospective clinical study
Marwa Ameen, Abdul Rahman Saleh, Dunia Alhadi, Manal Almaslamani
The Saudi Dental Journal.2025;[Epub] CrossRef - Application of Periapical Radiography in Root Canal Treatment: A Literature Review
Jennifer Lois Violita Malau, Keizha Allysia Nabila, Widiani Harrista, Regina Amara Ginting, Tassa Kusuma Arya Putri, Jatu Rachel Keshena
Acta Odontologica Indonesia.2025; 1(2): 49. CrossRef
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11,133
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Review Article
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Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
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Patrick Wesley Marques de Boa, Kaiza de Sousa Santos, Francisca Jennifer Duarte de Oliveira, Boniek Castillo Dutra Borges
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Restor Dent Endod 2024;49(2):e14. Published online March 20, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e14
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Abstract
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This study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clinical trials that compared the efficacy or the in-office bleaching sensitivity between carbamide and hydrogen peroxides were included. The risk of bias was evaluated using the RoB2. The certainty of the evidence was assessed using the GRADE approach. DPI training significantly improved the mean scores of the dental undergraduates from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. The limited evidence suggests that the 37% carbamide peroxide may be similarly effective to the 35% hydrogen peroxide for bleaching teeth in-office and causes less bleaching sensitivity. However, more well-designed split-mouth clinical trials are necessary to strengthen the evidence.
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- Impact of nanostructured additives in tooth bleaching agents on enhancing color change and reducing side effects: a scoping review
Patrick Wesley Marques de Boa, Kaiza de Sousa Santos, Aleph Matthews da Silva Souza, Arnóbio Antônio da Silva-Júnior, Boniek Castillo Dutra Borges
Clinical Oral Investigations.2025;[Epub] CrossRef - Quantitative and Qualitative Assessment of Enamel Surface Roughness Following High-Concentration Peroxide Bleaching: A Comparative In Vitro Study
Mamnoon Ghafir, Nida Mehmood, Leeza Bharati, Shreya Bhukal, Ritika Sethi, Aanchal Chaudhary, Seema Gupta
Cureus.2025;[Epub] CrossRef - Using violet light during in-office tooth bleaching to enhance the efficacy of carbamide peroxide without increasing bleaching sensitivity: a systematic review and meta-analysis
Mariana Silva de Bessa, Kaiza de Sousa Santos, Patrick Wesley Marques de Boa, Francisca Jennifer Duarte de Oliveira, Bárbara Faria de Sá Barbosa, Boniek Castillo Dutra Borges
Lasers in Medical Science.2025;[Epub] CrossRef - Influence of Different Light-Activated Bleaching Gels on Pulp Chamber Temperature: An In Vitro Study
Mandana Karimi, Elmira Ataee, Ladan Ranjbar Omrani, Mahdi Abbasi, Elham Ahmadi
Avicenna Journal of Dental Research.2024; 16(4): 225. CrossRef
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10,838
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4
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Research Articles
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Effect of surface treatment on glass ionomers in sandwich restorations: a systematic review and meta-analysis of laboratory studies
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Hoda S. Ismail, Ashraf Ibrahim Ali, Franklin Garcia-Godoy
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Restor Dent Endod 2025;50(2):e13. Published online April 16, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e13
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Abstract
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- Objectives
This study aimed to evaluate the effect of different surface treatments on the bond strength between new or aged glass ionomers (GI) and resin composites in sandwich restorations.
Methods
A comprehensive search was conducted in three databases to identify studies focusing on the bond strength of new or aged GIs and resin composites in laboratory settings. The selected studies were assessed for potential biases based on predetermined criteria. Additionally, a meta-analysis was performed using three studies.
Results
A total of 29 studies were included, with 24 investigating the bond strength of new GIs and five focusing on GI repair. Three studies were included in the meta-analysis (with a 95% confidence interval) which revealed no significant difference in the mean MPa values of resin-modified glass ionomer (RMGI) treated with phosphoric acid or Er,Cr:YSGG laser before the application of an etch-and-rinse adhesive. Surface treatment was found to be crucial for achieving optimal bonding between GI and resin composite, regardless of the GI’s condition.
Conclusions
The combination of mechanical and chemical surface treatments does not significantly affect the bond strength between new RMGI and composite. However, for GI repair, it is recommended to use both treatments to enhance the bond strength.
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- The impact of alloy treatment on the dynamic cyclic fatigue resistance of triangular base cross-section NiTi endodontic instruments
Rashid El Abed, Amre R. Atmeh, Mohamed Jamal, Anas Al Jadaa, Hamza El-Faraj, Abdel Rahman Bani Amer, Taher Al Omari
Odontology.2025;[Epub] CrossRef
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8,371
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Success rates comparison of endodontic microsurgery and single implants with comprehensive and explicit criteria: a systematic review and meta-analysis
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Min Jung Ko, Ju Hyun Park, Na Rae Lee, Joon-Ho Yoon, Young-Taek Kim, Sin-Yeon Cho
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Restor Dent Endod 2025;50(1):e8. Published online February 19, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e8
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Abstract
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Supplementary Material
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- Objectives
While the success criteria of endodontic microsurgery (EMS) have been consistently defined and widely accepted, the success criteria of dental implants are outdated and focus only on the implant fixture and surrounding bone. This study aimed to evaluate the outcomes of EMS and single implants (SIs) with explicit criteria.
Methods
We searched for articles published from January 2010 to February 2022 and discussed them and consulted with a clinical advisory committee composed of four dental specialists and one epidemiologist during article selection and data extraction.
Results
Twenty-two EMS studies and six SI studies were included in the meta-analysis. Teeth treated using EMS had a pooled success rate of 89% (90% at <5-year follow-up and 80% at ≥5-year follow-up) and the pooled success rate of SI was 78%.
Conclusions
The success rates of the two procedures with similar follow-up periods were comparable. Subgroup analysis found no other variable that significantly influenced study heterogeneity. Considering the treatment sequence and the similar success rates, it would be advantageous to consider EMS, rather than implants, first in a situation where both procedures are applicable.
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- Surgical Management of a Separated Instrument and Radicular Cyst: A Nine-Month Cone Beam Computed Tomography (CBCT) Follow-up
Dipti Chauhan, Hemant Yadav, Anshu Minocha, Vishal Sharma
Cureus.2025;[Epub] CrossRef - Cost-effectiveness of Endodontic Retreatment vs Implants: A 5-year Retrospective Analysis in India
Pramod Kumar, Himanshu Sharma
Journal of Clinical Insights and Research in Dentistry.2025; 1(3): 121. CrossRef
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8,355
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Pattern of endodontic instrument separation and factors affecting its retrieval: a 10-year retrospective observational study in a postgraduate institute
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Velmurugan Natanasabapathy, Aswathi Varghese, Paul Kevin Abishek Karthikeyan, Srinivasan Narasimhan
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Restor Dent Endod 2025;50(1):e7. Published online February 19, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e7
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Abstract
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- Objectives
This study aimed to assess the pattern of endodontic instrument separation, their retrievability, and factors affecting its retrieval, in a postgraduate institute.
Methods
Cases referred for the management of separated endodontic instruments (SEI) from 2013 to 2023 were considered for this study. Data related to demographics, tooth type, file type, and retrieval were documented in an Excel sheet. Eight prognostic factors assumed to influence the retrieval were analyzed in this study. The secondary aim was to compare the pattern of SEI and retrievability between conventional nickel-titanium files and newer generation heat-treated nickel-titanium files. Retrieval was attempted by a senior endodontist under the dental operating microscope. Various ultrasonic tips and a Broken Tool Removal loop system were used during retrieval. Simple descriptive statistics were performed. Binomial logistic regression was done to identify the effect of the eight prognostic factors on the retrieval outcome.
Results
A total of 190 SEI was reported. SEI occurred more often in posterior teeth than anterior teeth, mandibular arch than maxillary arch, and in larger files than smaller files. Separation occurred more often in the apical third compared to the other levels. Retrieval was attempted in 88 cases and successful in 70 cases (79.5%). The larger taper and apical position of the SEI negatively influenced the retrieval by 1.4 and 8.7 times, respectively.
Conclusions
Retrieval of SEI was successful in the majority of the cases. An increase in taper and apically placed SEI negatively impacted the retrieval. There was no difference in the pattern of separation nor retrievability between conventional nickel-titanium files and newer generation heat-treated nickel-titanium files.
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- Risk Factors for Failure of Separated Instrument Removal: A Systematic Review and Meta‐Analysis
Le Zhao, WangYu Luo, Yue Shen, WanNing Yu, Liu Yang, Xiaolei Zhang
Australian Endodontic Journal.2026;[Epub] CrossRef - Effectiveness of microscope-assisted root canal treatment in permanent posterior teeth: A retrospective cohort study
Ya-Ching Chang, Ting-Ya Wang
Journal of Dentistry.2025; 157: 105771. CrossRef - Deep Learning-Based Detection of Separated Root Canal Instruments in Panoramic Radiographs Using a U2-Net Architecture
Nildem İnönü, Umut Aksoy, Dilan Kırmızı, Seçil Aksoy, Nurullah Akkaya, Kaan Orhan
Diagnostics.2025; 15(14): 1744. CrossRef - MANAGEMENT OF INTRACANAL SEPARATED INSTRUMENTS: FACTORS CONTRIBUTING TO ENDODONTIC FILE SEPARATION — A NARRATIVE REVIEW
Tareq Hajaj, Paul Freiman , Serban Talpos Niculescu , Mihai Rominu , Tiberiu Hosszu , Ioana Veja
Romanian Journal of Oral Rehabilitation.2025; 17(2): 993. CrossRef
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Case Report
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Garre’s osteomyelitis of the mandible managed by nonsurgical re-endodontic treatment
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Heegyun Kim, Jiyoung Kwon, Hyun-Jung Kim, Soram Oh, Duck-Su Kim, Ji-Hyun Jang
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Restor Dent Endod 2024;49(2):e13. Published online March 18, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e13
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Chronic osteomyelitis with proliferative periostitis, known as Garre’s osteomyelitis, is a type of osteomyelitis characterized by a distinctive gross thickening of the periosteum of bones. Peripheral reactive bone formation can be caused by mild irritation or infection. Garre’s osteomyelitis is usually diagnosed in children and young adults, and the mandible is more affected than the maxilla. The following is a case report of a 12-year-old female patient with Garre’s osteomyelitis of the mandible due to an infection of a root canal-treated tooth. Without surgical intervention, the patient’s symptoms were relieved through nonsurgical root canal re-treatment with long-term calcium hydroxide placement. A cone-beam computed tomography image obtained 6 months after treatment completion displayed complete healing of the periapical lesion and resolution of the peripheral reactive buccal bone. Due to the clinical features of Garre's osteomyelitis, which is characterized by thickening of the periosteum, it can be mistaken for other diseases such as fibrous dysplasia. It is important to correctly diagnose Garre's osteomyelitis based on its distinctive clinical features to avoid unnecessary surgical intervention, and it can lead to minimally invasive treatment options.
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- Focal osteomyelitis with proliferative periostitis
Zarah Yakoob
South African Dental Journal.2025; 79(09): 508. CrossRef - Garré’s osteomyelitis of the mandible in an adolescent: a case report
Wiem Feki, Imen Haddar, Marwa Bahloul, Zeineb Mnif, Thouraya Kammoun, Ines Maaloul
Journal of Medical Case Reports.2025;[Epub] CrossRef - Garré’s Chronic Sclerosing Osteomyelitis: An Overview of Clinical and Radiologic Features
Mohamed Fadil, Ayman Farouki, Rachida Saouab, Hassan En-nouali, Jamal El Fenni, Zakariya Toufga
Oxford Medical Case Reports.2025;[Epub] CrossRef
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Research Articles
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Single-session associative protocol for dentin hypersensitivity management: a 1-year randomized, blinded clinical study
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Thayna Carolina Zeni, Poliana Maria de Faveri Cardoso, Rafael da Silva Vanolli, Márcio José Mendonça, Julio Katuhide Ueda, Veridiana Camilotti
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Restor Dent Endod 2024;49(2):e15. Published online March 20, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e15
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- Objectives
This study aimed to establish a single-session associative protocol for non-restorative management of dentin hypersensitivity (DH).
Materials and MethodsTwenty-four individuals with DH and a minimum sensitivity level of 4 on the visual analog scale (VAS) were selected. The study was conducted in a split-mouth design, with each participant (n = 20) having at least 1 affected tooth in all quadrants. The management protocols consisted of control group: universal adhesive, Neural Desensitizing Protocol group: 5% potassium nitrate, Mixed Desensitizing Protocol (PAM) group: 5% sodium fluoride and 5% potassium nitrate, Remineralizing Desensitizing Protocol (PDR) group: surface-partially reacted glass technology photopolymerizable varnish. Evaluations were performed immediately after application, at 1 week, 1 month, 2 months, and 12 months using the VAS sensitivity test.
ResultsThe scores were subjected to statistical analysis using the Friedman test (p < 0.05), Durbin-Conover test (p < 0.05), and Wilcoxon test (p < 0.05). At the 12-month evaluation, all groups showed statistically significant differences compared to the initial assessment. For the evaluation after 12 months, there was a statistically significant difference between the PAM group, the control group, and the PDR group.
ConclusionsIt can be concluded that all groups were effective in controlling DH, but there were significant results in the control group and PDR group. The clinical relevance of this study is to demonstrate that the application of single-session desensitizing protocols can be effective in controlling DH for up to 12 months.
Trial RegistrationBrazilian Clinical Trials Registry Identifier: RBR-4r63d7s
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- In vivo and in situ evaluation of innovative approaches in dentin hypersensitivity treatment
Heba Abd El-Fattah Mohamed, Dina Ezzeldin Mohamed, Elhassan Hassanein, Heba El-din Salah El-din Hamza
BMC Oral Health.2025;[Epub] CrossRef - Publication trends and scientific profile of clinical trials on universal adhesives in dentistry: A metrics-based review
Aurélio de Oliveira Rocha, Lucas Menezes dos Anjos, Michael Willian Favoreto, Michely Cristina Goebel, Bruno Henriques, Alessandra Reis, Alessandro D. Loguercio, Mariane Cardoso
Journal of Dentistry.2025; 161: 105965. CrossRef - EVALUATION OF PUSH-OUT BOND STRENGTH OF GLASS FIBER POSTS USING DIFFERENT LUTING CEMENTS
Jannah Mohammed, Maha Agha
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY.2025; : 274. CrossRef - EVALUATION OF PUSH-OUT BOND STRENGTH OF GLASS FIBER POSTS USING DIFFERENT LUTING CEMENTS
Jannah Mohammed, Jannah Mohammed
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY.2025; : 274. CrossRef - CLINICAL AND BEHAVIORAL DETERMINANTS OF DENTIN SENSITIVITY AMONG DENTAL STUDENTS: AN INSTITUTIONAL CROSS-SECTIONAL STUDY
Giuseppe Eliseo ALLOCCA, Alexandrina MUNTEAN , Cristian Doru OLTEANU , Sorana Maria BUCUR
Medicine and Materials.2025; 5(2): 73. CrossRef - Desensitizing efficacy of a universal dentin adhesive containing mesoporous bioactive glass on dentin hypersensitivity: a randomized clinical trial with a split-mouth model
Hyun-Jung Kim, Soram Oh, Jiyoung Kwon, Kyoung-Kyu Choi, Ji-Hyun Jang, Duck-Su Kim
Scientific Reports.2024;[Epub] CrossRef
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Effects of different curing methods on the color stability of composite resins
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Massimo Pisano, Alfredo Iandolo, Dina Abdellatif, Andrea Chiacchio, Marzio Galdi, Stefano Martina
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Restor Dent Endod 2024;49(4):e33. Published online September 5, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e33
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- Objectives
The aim of this study was to compare the effects of different polymerization strategies and the effectiveness of finishing and polishing procedures of composite resins on color stability.
Materials and MethodsThe samples were divided into 4 main groups according to the polymerization strategy, and all groups except the control group received surface treatment. Each group was subsequently divided into 3 subgroups respectively: Kuraray Clearfil Majesty ES-2 Classic, Premium and Universal. Approximately 24 hours after preparation of the samples, they were immersed for 7 days in a coffee solution. A first color measurement was performed after the preparation of the samples, the second measurement was performed after 7 days in the coffee solution. All measurements were carried out using a dental spectrophotometer to assess the CIE L* a* b* color parameters.
ResultsThere was a statistically significant difference between ΔE values for different procedures (p = 0.003); in particular, the differences were found only between the groups that received surface treatment and the control group. In addition, a statistically significant difference was observed between the values of ΔE for different composites in the different procedure groups.
ConclusionsSpectrophotometric analysis showed that the additional photopolymerization and oxygen inhibition procedures did not yield better results in relation to color stability. In addition, finishing and polishing provided better color stability compared to not performing these procedures.
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- Color Stability Under Challenge: Effects of Thermo-Aging and Mouthrinse Exposure on Anterior Teeth and Esthetic Composites
Gökçe Keçeci, Zehra Güner, Süleyman Ziya Şenyurt, Kamile Erciyas
European Journal of Therapeutics.2026;[Epub] CrossRef - Abrasiveness and Bleaching Level of Toothpastes on Composite Resins: A Quantitative Analysis Using a Novel Brushing Simulator
Simge Meseli, Elif Alkan, Bora Korkut, Ozlem Kanar, Dilek Tagtekin
Applied Sciences.2025; 15(5): 2314. CrossRef - Comparative Evaluation of Direct and Indirect Composite Restorations in Class II Tooth Preparations - An In vivo Study
Akshun Gupta, Garima Arora, Aprajita Mehta, Satish Sane, Siddhi Nevrekar, Apurva Nagrale
Advances in Human Biology.2025; 15(4): 550. CrossRef - Micro- and Nanoplastics and the Oral Cavity: Implications for Oral and Systemic Health, Dental Practice, and the Environment—A Narrative Review
Federica Di Spirito, Veronica Folliero, Maria Pia Di Palo, Giuseppina De Benedetto, Leonardo Aulisio, Stefano Martina, Luca Rinaldi, Gianluigi Franci
Journal of Functional Biomaterials.2025; 16(9): 332. CrossRef
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5,950
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Review Article
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A global overview of enamel microabrasion for white spot lesions: a bibliometric review
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Aurélio de Oliveira Rocha, Karina Cardoso, Michely Cristina Goebel, Pablo Silveira Santos, Lucas Menezes dos Anjos, Juliana Silva Ribeiro, Carla Miranda Santana, Mariane Cardoso
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Restor Dent Endod 2024;49(3):e29. Published online July 11, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e29
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Abstract
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Supplementary Material
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This study aimed to identify and analyze articles on enamel microabrasion for the treatment of white spot lesions. A search was conducted on the Web of Science. The following parameters were recorded and analyzed: number of citations, year, journal, impact factor, study design, theme, country and continent, institution, authors, and keywords. Data was analyzed using VOSviewer software. The initial search resulted in 1,126 documents, of which 94 articles were included. The highest number of citations an article received was 65. The oldest article was published in 1975, and the most recent in 2023. The most frequent study design was case report (n = 42). Regarding the themes, it was observed that the main objective of the studies was to evaluate the clinical performance of enamel microabrasion (n = 75), primarily using Opalustre (Ultradent Products Inc., South Jordan, UT, USA) (n = 37) for treating white stains caused by dental fluorosis (n = 41). Most articles originated from Latin America (n = 31), mainly from Brazil (n = 26). The most frequent author was Sundfeld RH (n = 10). This study reveals research trends in the field of enamel microabrasion. The publications were mainly case reports/series using Opalustre for the removal of fluorosis stains.
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- Impact of microabrasion and a remineralizing agent before in-office bleaching on hydrogen peroxide permeability, color alteration, and enamel morphology
Michael Willian Favoreto, Leticia Condolo, Camila Mendes Camargo, Rafael Rodrigues Lima, Karol Carrillo, Abraham Lincoln Calixto, Alessandra Reis, Alessandro D. Loguercio
Journal of Dentistry.2025; 156: 105655. CrossRef - Micro- and Macroabrasion in the Esthetic Zone: A Narrative Review and Case Study
Jose Villalobos-Tinoco, Carlos A. Jurado, Silvia Rojas-Rueda, Nechama S. Citrin, Staley Colvert, Jose Luis Gutierrez-Quintero, Salwa Mekled
Dentistry Journal.2025; 13(5): 183. CrossRef - Evaluation of demineralization changes in molar tissues in vitro using electrical impedance spectroscopy
V. D. Goncharov, M. A. Gorelikova, K. V. Shadrina, L. Yu. Orekhova, V. D. Berezkin, E. S. Nemovskaya, A. A. Petrov
Parodontologiya.2025; 30(3): 254. CrossRef
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Research Articles
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Effects of a relined fiberglass post with conventional and self-adhesive resin cement
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Wilton Lima dos Santos Junior, Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Luís Roberto Marcondes Martins
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Restor Dent Endod 2024;49(2):e18. Published online March 27, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e18
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Abstract
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- Objectives
This study was conducted to evaluate the mechanical properties of relined and non-relined fiberglass posts when cemented to root canal dentin using a conventional dual-cure resin cement or a self-adhesive resin cement.
Materials and MethodsTwo types of resin cements were utilized: conventional and self-adhesive. Additionally, 2 cementation protocols were employed, involving relined and non-relined fiberglass posts. In total, 72 bovine incisors were cemented and subjected to push-out bond strength testing (n = 10) followed by failure mode analysis. The cross-sectional microhardness (n = 5) was assessed along the root canal, and interface analyses (n = 3) were conducted using scanning electron microscopy (SEM). Data from the push-out bond strength and cross-sectional microhardness tests were analyzed via 3-way analysis of variance and the Bonferroni post-hoc test (α = 0.05).
ResultsFor non-relined fiberglass posts, conventional resin cement exhibited higher push-out bond strength than self-adhesive cement. Relined fiberglass posts yielded comparable results between the resin cements. Type II failure was the most common failure mode for both resin cements, regardless of cementation protocol. The use of relined fiberglass posts improved the cross-sectional microhardness values for both cements. SEM images revealed voids and bubbles in the incisors with non-relined fiberglass posts.
ConclusionsMechanical properties were impacted by the cementation protocol. Relined fiberglass posts presented the highest push-out bond strength and cross-sectional microhardness values, regardless of the resin cement used (conventional dual-cure or self-adhesive). Conversely, for non-relined fiberglass posts, the conventional dual-cure resin cement yielded superior results to the self-adhesive resin cement.
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- Push-Out Bond Strength of Different Luting Cements Following Post Space Irrigation with 2% Chitosan: An In Vitro Study
Shimaa Rifaat, Ahmed Rahoma, Hind Muneer Alharbi, Sawsan Jamal Kazim, Shrouq Ali Aljuaid, Basmah Omar Alakloby, Faraz A. Farooqi, Noha Taymour
Prosthesis.2025; 7(1): 18. CrossRef
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Surface properties and susceptibility to staining of a resin composite after brushing with different whitening toothpastes
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Aline da Silva Barros, Carolina Meneghin Barbosa, Renata Siqueira Scatolin, Waldemir Francisco Vieira Junior, Laura Nobre Ferraz
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Restor Dent Endod 2025;50(1):e6. Published online February 26, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e6
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Abstract
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- Objectives
This study investigated the effects of different whitening toothpaste (WT) on the surface properties and staining susceptibility of a resin composite.
Methods
Cylindrical samples were prepared with a micro-hybrid resin composite and were randomized into groups according to the toothpaste (n = 12): distilled water (DW), regular toothpaste (RT), WT with silica + pyrophosphate (WT-S/P), WT with pentaphosphate and pyrophosphate (WT-P/P), WT with hydrogen peroxide and pyrophosphate (WT-HP/P) and WT with charcoal and pyrophosphate (WT-Ch/P). The samples were brushed for 825 cycles in an automatic brushing machine, simulating 30 days of brushing. After that, an immersion in coffee (10 mL/sample) was performed for 30 minutes for 30 days. The analyses of color, surface microhardness (SMH), and surface roughness (Ra) were performed at the initial time, after brushing with toothpaste and after immersion in coffee. The ΔL*, Δa*, Δb*, ΔEab, Δand E00 values were calculated comparing after toothpaste with initial time and after coffee with after toothpaste. Data were analyzed using a mixed linear model for repeated measures (SMH), Kruskal-Wallis, Dunn, Friedman, and Nemenyi tests, with α = 0.05.
Results
For ΔL*, the WT-Ch/P group had the lowest values and differed from the other groups comparing the after toothpaste with the initial time interval (p < 0.001). The WT-Ch/P group had the lowest SMH values in after-toothpaste time (p < 0.001). In after-toothpaste time and after coffee time, the WT-S/P group had the highest Ra values and differed from the groups except the WT-Ch/P group (p < 0.001).
Conclusions
The toothpaste composition affects the surface characteristics and susceptibility to staining of the resin composite. The charcoal-based toothpaste had the worst performance for the color analyses and SMH.
Review Article
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Comparative evaluation of the biological response of conventional and resin modified glass ionomer cement on human cells: a systematic review
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Shishir Singh, Gaurav Kulkarni, R S Mohan Kumar, Romi Jain, Ameya M Lokhande, Teena K Sitlaney, Musharraf H F Ansari, Navin S Agarwal
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Restor Dent Endod 2024;49(4):e41. Published online November 1, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e41
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Abstract
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This review aimed to evaluate and compare the biological response (biocompatibility and cytotoxicity) of resin modified glass ionomer cement (RMGIC) in contrast to conventional glass ionomer cement (GIC) on human cells. Articles reporting parallel and split-mouth clinical trials, randomized controlled trials, non-randomized controlled trials, prospective studies, and in vitro studies on human permanent teeth that assessed the biological response of GIC and RMGIC were included. The following electronic bibliographic databases were searched using the keywords: MEDLINE/PubMed, EBSCO, Cochrane Central Register of Controlled Trials, and Google Scholar. For the risk of bias MINORS tool and the modified scale of Animal Research: Reporting of In Vivo Experiments and Consolidated Standards of Reporting Trials were used. Initial screening identified 552 studies, of which 9 articles met the inclusion criteria and were included in the study. Different parameters such as odontoblastic changes, inflammatory response, tertiary dentin formation, presence of microorganisms, morphological changes, cell viability, number, and metabolism were used to evaluate the biological response of conventional GIC and RMGICs. Conventional GIC shows lower cytotoxicity compared to RMGIC in vital pulp therapy procedures. Further, in vivo studies and long-term clinical trials are needed to compare these observations for pulp therapy using the 2 test materials.
Trial RegistrationPROSPERO Identifier: CRD42023426021
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- Thermal Aging-Induced Alterations in Surface and Interface Topography of Bio-Interactive Dental Restorative Materials Assessed by 3D Non-Contact Profilometry
Zehra Güner, Gökçe Keçeci, Sadık Olguner, Hakan Çandar, Ayşenur Güngör Borsöken, Lezize Sebnem Turkun
Coatings.2026; 16(1): 53. CrossRef - Advanced Platelet-Rich Fibrin Plus Sealed Exclusively with Glass Ionomer Cement: Setting a New Standard for Healing, Aesthetics and Predictive Modelling in Regenerative Endodontics
Dubravka Turjanski, Dragutin Lisjak, Petra Bučević Sojčić, Jelena Valpotić, Tea Borojević Renić, Kristina Goršeta, Domagoj Glavina
Materials.2025; 18(18): 4421. CrossRef - The conventional glass ionomers – A forgotten paradigm
Shishir Singh
Journal of Conservative Dentistry and Endodontics.2024; 27(12): 1201. CrossRef
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Research Article
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Prevalence of apical periodontitis and quality of root canal treatment in an adult Kuwaiti sub-population: a cross-sectional study
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Abdulrahman A. Alhailaa, Saad A Al-Nazhan, Mazen A Aldosimani
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Restor Dent Endod 2024;49(2):e16. Published online March 22, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e16
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- Objectives
This cross-sectional study evaluated the prevalence of apical periodontitis (AP) and the technical quality of root canal fillings in an adult Kuwaiti subpopulation using cone-beam computed tomography (CBCT) images.
Materials and MethodsTwo experienced examiners analyzed 250 CBCT images obtained from Kuwaiti patients aged 15–65 years who attended government dental specialist clinics between January 2019 and September 2020. The assessment followed the radiographic scoring criteria proposed by De Moor for periapical status and the technical quality of root canal filling. Chi-square and Fisher’s exact tests were used for statistical analysis, with significance level set at p < 0.05.
ResultsAmong the 2,762 examined teeth, 191 (6.91%) exhibited radiographic signs of AP, and 176 (6.37%) had undergone root canal filling. AP prevalence in root canal-treated teeth was 32.38%, with a significant difference between males and females. Most of the endodontically treated teeth exhibited adequate root canal filling (71.5%).
ConclusionsThe study demonstrated a comparable prevalence of AP and satisfactory execution of root canal treatment compared to similar studies in different countries.
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- A Retrospective Study of CBCT-Based Detection of Endodontic Failures and Periapical Lesions in a Romanian Cohort
Oana Andreea Diaconu, Lelia Mihaela Gheorghiță, Anca Gabriela Gheorghe, Mihaela Jana Țuculină, Maria Cristina Munteanu, Cătălina Alexandra Iacov, Virginia Maria Rădulescu, Mihaela Ionescu, Adina Andreea Mirea, Carina Alexandra Bănică
Journal of Clinical Medicine.2025; 14(18): 6364. CrossRef
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4,653
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Case Report
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Straightforward replication of digital wax-up design into direct composite resin restorations in adolescents using a custom 3-dimensionally printed index
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Ra’fat Ibrahim Farah, Sanaa Najeh Al-Haj Ali, Abdullah Alharbi, Bandar Alresheedi
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Restor Dent Endod 2024;49(4):e36. Published online October 10, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e36
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This case report introduces a straightforward, noninvasive approach for the esthetic rehabilitation of malformed anterior teeth in adolescents using direct composite restorations. The universal composite resin restorations are applied within a transparent 3-dimensionally printed rigid-resin index, which is individually customized from a digital wax-up. Compared to other methods, this technique streamlines the restoration process, significantly reducing chairside time while enhancing the predictability, accuracy, and patient acceptance of the aesthetic outcome.
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- Diastema closure and esthetic rehabilitation with peg-shaped laterals: A case series
Afsana Ansari, Dipika Yadav
The Saint's International Dental Journal.2024; 8(2): 48. CrossRef
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Research Articles
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Concentrated growth factor scaffold-based pulpotomy of permanent molars with symptomatic irreversible pulpitis
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Arthi K. Harith, Vishnupriya Koteeswaran, Dinesh Kowsky, Natanasabapathy Velmurugan, Suresh Nandini
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Restor Dent Endod 2025;50(1):e1. Published online January 17, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e1
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Pulpotomy is a minimally invasive procedure that aims to retain the vitality of the radicular pulp by removing the inflamed coronal pulp tissue. This case series presents the successful management of symptomatic irreversible pulpitis by pulpotomy with concentrated growth factor (CGF) scaffolds.
Methods
Six permanent mandibular molars with a diagnosis of symptomatic irreversible pulpitis were included. Under Local anesthesia and rubber dam isolation, caries were excavated using high-speed bur under coolant. Full coronal pulpotomy was done and hemostasis was achieved. CGF membrane was prepared and placed over the radicular pulp and layered with Biodentine (Septodont). Final restoration of type IX glass ionomer cement and bulk fill composite resin was placed. Patients were assessed for various clinical and radiographic parameters at intervals of 1 week and 3, 6, and 12 months. Five patients fulfilled the success criteria at the end of 1 year.
Results
Pulpotomy is considered an alternative treatment modality for root canal treatment in symptomatic irreversible pulpitis aiming at alleviating symptoms and maintaining vitality. CGF scaffold when used as a capping material acts as a reservoir for growth factors with anti-inflammatory properties and enhances healing.
Conclusions
Scaffold-based pulpotomy can be considered a biological approach to healing inflamed pulp.
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Evaluation of the effects of different file systems and apical functions of integrated endodontic motors on debris extrusion: an ex vivo experimental study
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Sıla Nur Usta, Antonio Magan-Fernandez, Cumhur Aydın
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Restor Dent Endod 2025;50(2):e14. Published online April 14, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e14
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This study aimed to evaluate the effects of two different file systems operated with three apical functions of an endodontic motor integrated with an electronic apex locator on debris extrusion.
Methods
Sixty single-rooted teeth were prepared and divided into two main groups and three subgroups based on the file system (OneShape [Micro-Mega SA] and WaveOne [Dentsply Maillefer]) and apical function of the endodontic motor used (auto apical stop [AAS], auto apical reverse [AAR], and auto apical slowdown [ASD]). The teeth were mounted in pre-weighed glass tubes filled with 0.9% sodium chloride to complete the circuit with the apex locator. Files were advanced until the respective apical function (stop, reverse, or slowdown) was activated. The extruded debris was collected, dried, and weighed by subtracting pre-weighed values from post-weighed values. Preparation time was also recorded. Statistical analyses were performed to compare the groups.
Results
OneShape was associated with significantly less debris extrusion compared to WaveOne, regardless of the apical function (p < 0.05). The ASD function resulted in the least debris extrusion compared to AAS and AAR (p < 0.05). Preparation time was significantly longer in the ASD function (p < 0.05), while no differences were observed between the file systems (p > 0.05).
Conclusions
The OneShape file system and the ASD function produced the least amount of apical debris. While the ASD function requires more preparation time, its potential to minimize debris extrusion suggests it may reduce postoperative symptoms.
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- Inflammatory Mediator Levels and Postoperative Pain Following Root Canal Shaping with Different Apical Actions: A Randomized Controlled Trial
Mustafa Mert Tulgar, Yağmur Kılıç, Oğuz Karalar, Huriye Erbak Yılmaz, Emrah Karataşlıoğlu
Journal of Endodontics.2025;[Epub] CrossRef
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Alkasite restorative material for endodontically treated teeth: a randomized controlled pilot study
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Davi Ariel Nobuo Bepu, Renata Siqueira Scatolin, Natalia Saud Junqueira Franco, Luiza Pejon Sanchez, Aline Evangelista Souza-Gabriel, Silmara Aparecida Milori Corona
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Restor Dent Endod 2024;49(3):e24. Published online June 11, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e24
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This study aimed to evaluate the clinical performance of an alkasite restorative material in molars that had undergone root canal treatment.
Materials and MethodsThe research was registered in Brazilian Registry of Clinical Trials. The randomized clinical trial involved 33 patients, each with at least 1 mandibular molar requiring restoration after receiving endodontic treatment. Patients were randomly assigned to receive either bulk-fill resin composite (Tetric N Ceram Bulk Fill, Ivoclar Vivadent) or the alkasite restorative material (Cention N, Ivoclar Vivadent). Upon completion of the restorations, 3 calibrated professionals utilized the United States Public Health Service criteria to assess various factors, including retention, secondary caries, marginal adaptation, restoration color, marginal pigmentation, and anatomical form. Evaluations were conducted at intervals of 7 days, 6 months, and 17 months. Additionally, the assessment encompassed the presence of radiolucent lines adjacent to the restoration, material deficiencies or excess, contact points, and caries recurrence. The data underwent analysis using the Friedman and Mann-Whitney tests (α = 0.05).
ResultsAfter 17 months, the results revealed that the alkasite restorative material exhibited greater wear of anatomical shape compared to the bulk-fill resin composite (p = 0.0189). Furthermore, the alkasite restorative material significantly differed from the natural tooth color in most cases (p = 0.0000). However, no other criteria displayed significant differences between the materials or over time (p > 0.05).
ConclusionsThe alkasite restorative material (Cention N) emerges as a viable option for restoring endodontically treated teeth, displaying clinically acceptable alterations after a 17-month evaluation period.
Trial RegistrationBrazilian Registry of Clinical Trials (ReBEC) Identifier: RBR-97kx5jv
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- The Effect of Intraorifice Barrier Materials on the Fracture Resistance of Endodontically Treated Teeth: A Systematic Review and Network Meta-Analysis
Sevilay Karahan, Zeynep Buket Dağ, Emel Uzunoğlu Özyürek
Journal of Endodontics.2026;[Epub] CrossRef - A Systematic Review and Meta-Analysis on the Clinical Performance and Longevity of Bioactive Composite Resin Restorations
Ahmed A. Holiel, Mounir M. Al Nakouzi, Rim Bourgi, Carlos Enrique Cuevas-Suárez, Iván Olivares Acosta, Louis Hardan, Naji Kharouf, Youssef Haikel
Journal of Composites Science.2026; 10(1): 39. CrossRef - Alkasites in restorative dentistry: a review of their performance and properties
Alexander Bonchev, Ralitsa Bogovska-Gigova
Journal of Dentistry.2025; 160: 105916. CrossRef - Comparative Analysis of Flexural and Compressive Strengths of Bioactive Alkasite Compared to Other Ion-Releasing Restorative Materials
Hanin E. Yeslam, Fatin A. Hasanain
Biomimetics.2025; 10(11): 751. CrossRef
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Case Reports
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Guided endodontics, precision and predictability: a case series of mineralized anterior teeth with follow-up cone-beam computed tomography
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Rafael Fernández-Grisales, Wilder Javier Rojas-Gutierrez, Pamela Mejía, Carolina Berruecos-Orozco, Néstor Ríos-Osorio
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Restor Dent Endod 2025;50(1):e4. Published online January 6, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e4
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- Pulp chamber and root canal obliteration (PCO/RCO) presents a challenge for clinicians when nonsurgical endodontic treatment is indicated. Guided endodontics (GE) aims to precisely locate the root canal (RC) system while preserving as much pericervical dentin as possible. GE involves integrating cone-beam computed tomography (CBCT) of the affected tooth with a digital impression of the maxillary/mandibular arch, allowing for careful planning of the drilling path to the RC system through a three-dimensional (3D) static guide. This article reports four cases of teeth with PCO/RCO, accompanied by additional diagnoses of internal and external root resorption and horizontal tooth fracture, all successfully treated with GE. These cases highlight the clinical and radiographic success of GE treatments using CBCT, establishing this technique as a predictable approach for managing mineralized teeth.
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Surgical management of maxillary sinusitis of endodontic origin after reestablishing maxillary sinus floor healing through a nonsurgical approach: a case report
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Eun-Sook Kang, Min-Kyeong Kim, Mi-Kyung Yu, Kyung-San Min
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Restor Dent Endod 2025;50(2):e12. Published online April 8, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e12
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- When root canal infections breach the maxillary sinus floor (MSF), maxillary sinusitis of endodontic origin (MSEO) can result. This case illustrates the surgical management of MSEO following the nonsurgical reestablishment of the MSF. A 55-year-old woman presented with left facial pain and was diagnosed with MSEO originating from the left upper first molar. Despite undergoing nonsurgical root canal treatment, there was no evidence of bony healing after 6 months. However, cone-beam computed tomographic (CBCT) scans revealed the reestablishment of MSF. Subsequently, surgical intervention was carried out using a dental operating microscope. Two years after surgery, CBCT images indicated that the mucosal edema had resolved, and the MSF was well reestablished. Preserving the MSF is crucial for the success of endodontic surgery. When MSEO is present, the integrity of the MSF must be assessed to determine appropriate treatment options.
Research Articles
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The status of clinical trials regarding root canal sealers
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Ahmad AL Malak, Yasmina EL Masri, Mira Al Ziab, Nancy Zrara, Tarek Baroud, Pascale Salameh
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Restor Dent Endod 2024;49(1):e5. Published online January 15, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e5
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This study aimed to present the results and analyses of clinical trials, including updates on the different functions of root canal sealers.
Materials and MethodsIn June 2023, we performed a comprehensive search of ClinicalTrials.gov to identify interventional clinical trials pertaining to root canal sealers. In total, 23 clinical trials conducted up to June 2023 were included in this study.
ResultsApproximately half of the trials (11 out of 23) were completed, while none were terminated or withdrawn. Each included trial had a minimum of 10 participants, with 11 trials having more than 100 participants. None of the assessed trials provided outcomes, and the majority (17 out of 23) lacked associated publications. In terms of geographic distribution, the USA and Canada did not contribute to any root canal sealer trials.
ConclusionsThis study highlights the lack of diversity in trial locations, the absence of reported results, and a scarcity of clinical trials examining the physicochemical properties of different sealers. Most published trials primarily focused on assessing the post-operative pain effect of these sealers, but no significant difference was found regarding post-operative pain control.
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Impact of the use of high-power 810-nm diode laser as monotherapy on the clinical and tomographic success of the treatment of teeth with periapical lesions: an observational clinical study
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Fabricio Hinojosa Pedraza, Abel Victor Isidro Teves-Cordova, Murilo Priori Alcalde, Marco Antonio Hungaro Duarte
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Restor Dent Endod 2025;50(2):e15. Published online May 15, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e15
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The aim of this study was to demonstrate the impact of a high-power 810-nm diode laser as monotherapy on the clinical and tomographic success of treating teeth with periapical lesions, through a series of 31 cases.
Methods
Teeth with apical lesions underwent endodontic treatment in which a high-power 810-nm diode laser with saline solution was used as monotherapy for disinfection. This type of therapy aimed to replace the traditional irrigation protocol with sodium hypochlorite. This research is the first to assess the clinical success of this alternative treatment, along with tomographic evaluations conducted over periods ranging from 2 to 7 years, analyzed using the periapical index based on cone-beam computed tomography (CBCTPAI). All cases were performed by a single clinician following the same laser protocol, which involved using 1 W of continuous power and four cycles of 20 seconds of laser activation.
Results
All teeth showed no clinical symptoms upon follow-up examination. However, the tomographic evaluation revealed that the success rates for teeth receiving primary treatment were 60% and 80% according to strict and loose criteria, respectively. For teeth requiring retreatment, the success rates were 12.5% and 37.5% using strict and loose criteria, respectively.
Conclusions
The teeth with apical lesions that underwent primary treatment did not present clinical symptoms, but they showed a moderate success rate on tomographic evaluation. However, despite lacking clinical symptoms, teeth with apical lesions that required retreatment had a very low success rate on tomographic evaluation.
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- Diode Laser-Guided Protocol for Endo-Perio Lesions: Toward a Multi-Stage Therapeutic Strategy—A Case Series and Brief Literature Review
Ioana-Roxana Munteanu, George-Dumitru Constantin, Ruxandra-Elena Luca, Ioana Veja, Mariana-Ioana Miron
Medicina.2025; 61(12): 2157. CrossRef
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3,711
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Cleaning protocols to enhance bond strength of fiberglass posts on root canals filled with bioceramic sealer: an in vitro comparative study
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Thiago Bessa Marconato Antunes, Juliana Delatorre Bronzato, Joice Graciani, Ana Cristina Padilha Janini, Rocharles Cavalcante Fontenele, Francisco Haiter Neto, Brenda Paula Figueiredo de Almeida Gomes, Marina Angélica Marciano da Silva
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Restor Dent Endod 2025;50(2):e20. Published online May 21, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e20
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- Objectives
This study aimed to evaluate whether the agitation protocols using ultrasonic inserts or the XP-endo Finisher R file improved the removal of two different endodontic sealer remnants and the bond strength of fiberglass posts to dentin.
Methods
Seventy-two human teeth were selected. The canals were prepared with Reciproc 50 and Easy ProDesign 30/.10 and root filled according to the endodontic sealer groups: AH Plus or EndoSequence BC Sealer HiFlow. The samples were kept at 37ºC and 95% humidity for 28 days. During the post space preparation, the obturation was removed with Largo burs, and the groups were divided according to the irrigant agitation protocols (n = 12): no agitation, agitation with R1-Clearsonic associated with E1-Irrisonic ultrasonic inserts, or agitation with XP-endo Finisher R file. The fiberglass posts were cemented with RelyX ARC. The roots were sectioned into slices and submitted to the push-out test. Micro-computed tomography analysis was used to check the effectiveness of irrigating solution agitation in the elimination of remnants.
Results
The cleaning protocols with agitation were more effective in increasing the bond strength of posts to dentin for both sealer groups compared to non-agitation (p < 0.05). There was no difference between the same cleaning protocols for the different sealers. Among the different thirds, there was no statistical difference for the same sealer in the different cleaning protocols (p > 0.05).
Conclusions
Both agitation protocols effectively clean root-filled canals sealed with resin-based and calcium silicate-based sealers during fiberglass post space preparation. These protocols result in improved bond strength compared to non-agitation methods.
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- Cleaning efficacy and bond interaction of glycine-based air polishing and glass microparticles abrasion on dentin impregnated with premixed bioceramic sealer
Ândresson Aurélio Fernandes Martins, Maria Carolina Sidonio Alves, Bruno Martins Maciel, José Rodolfo Estruc Verbicário, João Felipe Besegato, Wilfredo Gustavo Escalante-Otárola, Milton Carlos Kuga
International Journal of Adhesion and Adhesives.2026; 147: 104277. CrossRef
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Review Article
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Influence of disinfecting solutions on the surface topography of gutta-percha cones: a systematic review of in vitro studies
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Lora Mishra, Gathani Dash, Naomi Ranjan Singh, Manoj Kumar, Saurav Panda, Franck Diemer, Monika Lukomska-Szymanska, Barbara Lapinska, Abdul Samad Khan
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Restor Dent Endod 2024;49(4):e42. Published online November 1, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e42
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Supplementary Material
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The surface integrity of gutta-percha cones is a crucial factor in the success of endodontic procedures. Disinfecting solutions play a pivotal role in sterilizing gutta-percha cones, but their influence on gutta-percha surface topography remains a subject of concern. This systematic review aimed to present a qualitative synthesis of available laboratory studies assessing the influence of disinfecting solutions on the surface topography of gutta-percha and offers insights into the implications for clinical practice. The present review followed PRISMA 2020 guidelines. An advanced database search was performed in PubMed, Google Scholar, Embase, Scopus, LILAC, non-indexed citations and reference lists of eligible studies in May 2024. Laboratory studies, in English language, were considered for inclusion. The quality (risk of bias) of the included studies was assessed using parameters for in vitro studies. A total of 28 studies were included in the qualitative synthesis. Based on the included in vitro studies, surface deposits and alterations in the physical properties of gutta-percha cones were observed after the disinfection protocol. A comprehensive review of the available literature indicates that the choice of disinfecting solution, its concentration, and immersion time significantly affect the surface topography of gutta-percha cones.
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- In Vitro Evaluation of Disinfectants on Gutta-Percha Cones: Antimicrobial Efficacy Against Enterococcus faecalis and Candida albicans
Tringa Kelmendi, Donika Bajrami Shabani, Aida Meto, Hani Ounsi
Journal of Clinical Medicine.2025; 14(19): 6846. CrossRef
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Case Report
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A 48-month clinical performance of hybrid ceramic fragment restorations manufactured in CAD/CAM in non-carious cervical lesions: case report
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Michael Willian Favoreto, Gabriel David Cochinski, Eveline Claudia Martini, Thalita de Paris Matos, Matheus Coelho Bandeca, Alessandro Dourado Loguercio
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Restor Dent Endod 2024;49(3):e32. Published online August 5, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e32
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From the restorative perspective, various methods are available to prevent the progression of non-carious cervical lesions. Direct, semi-direct, and indirect composite resin techniques and indirect ceramic restorations are commonly recommended. In this context, semi-direct and indirect restoration approaches are increasingly favored, particularly as digital dentistry becomes more prevalent. To illustrate this, we present a case report demonstrating the efficacy of hybrid ceramic fragments fabricated using computer-aided design (CAD)/computer-aided manufacturing (CAM) technology and cemented with resin cement in treating non-carious cervical lesions over a 48-month follow-up period. A 24-year-old male patient sought treatment for aesthetic concerns and dentin hypersensitivity in the cervical region of the lower premolar teeth. Clinical examination confirmed the presence of two non-carious cervical lesions in the buccal region of teeth #44 and #45. The treatment plan involved indirect restoration using CAD/CAM-fabricated hybrid ceramic fragments as a restorative material. After 48 months, the hybrid ceramic material exhibited excellent adaptation and durability provided by the CAD/CAM system. This case underscores the effectiveness of hybrid ceramic fragments in restoring non-carious cervical lesions, highlighting their long-term stability and clinical success.
Research Articles
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Can discolored dental composites be bleached in depth?
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Luca Giachetti, Daniele Scaminaci Russo, Michele Nieri, Francesca Cinelli
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Restor Dent Endod 2024;49(3):e23. Published online June 11, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e23
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Previous in vitro studies determined the whitening effects of bleaching products on stained resin composite surfaces. This in vitro study aimed to verify the effectiveness of a whitening system on composite resin previously subjected to pigmentation, specifically examining the depth of whitening effectiveness within the material structure.
Materials and MethodsA commercially available nano-filled composite resin was used. Specimens were stained using a coffee-based solution and a 10% carbamide peroxide-based gel was employed as the whitening agent. The pigment’s penetration and the effect of the bleaching gel were evaluated by measuring color (CieLab values) from the outer edge to the inner part of the specimens. Color measurements were taken at 14 points, starting from 0.1 mm from the external perimeter up to 3.0 mm.
ResultsAnalysis of variance tests showed a statistically significant difference between the Control Group (CG), Pigmentation Group, and Whitening Group. The whitening agent was effective up to 1.5 mm in depth, with Whiteness index (W) values not statistically different from those of CG up to 0.5 mm in depth.
ConclusionsWhitening agents on nano-filled resin composite previously pigmented appear effective in restoring the W to values similar to the original, particularly in the superficial layers of the sample.
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- Color Stability of Tooth-Colored Restorative Materials After Exposure to Arabic Coffee and Black Tea: A Systematic Review
Abdulrhman Y Alenezi, Abdulwahab M AlEyada, Yousef H Aldhafiri, Mohammed S Alsubaie, Mohammed S Alshahrani, Mahesh Shenoy
Cureus.2025;[Epub] CrossRef - Comparative evaluation to composite resin bleaching using ozone-enhanced low-concentration hydrogen peroxide
Mahmoud K. AL-Omiri, Dania Sa’ed Hussam Abuherra, Khaled M. AL-Omiri, Ali Y. Alsaeed, Mohammad Alamri, Ali M. Alqahtani, Saleh Ali Alqahtani, Ghadeer Saleh Alwadai, Naif Abogazalah, Edward Lynch
Scientific Reports.2025;[Epub] CrossRef - The effects of mechanical and chemical degradation on the surface roughness, gloss, and color stability of bulk-fill resin composites
Merve Nezir, Hanife Altınışık, Esra Özyurt, Naz Bayar, Mediha Büyükgöze Dindar
BMC Oral Health.2025;[Epub] CrossRef
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Pulp stones: any relevance with the levels of serum calcium, parathyroid hormone, vitamin D and uric acid
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Ceyda Gürhan, Ercan Saruhan
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Restor Dent Endod 2024;49(2):e17. Published online March 26, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e17
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- Objectives
This study evaluated the effect of serum calcium, parathyroid hormone (PTH), vitamin D, and uric acid levels on pulp stone formation.
Materials and MethodsPatients who were admitted to the Muğla Sıtkı Koçman University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology for dental complaints were registered. Among these patients, individuals who had routine biochemical tests at the same period in the Outpatient Clinics of Muğla Sıtkı Koçman University Training and Research Hospital were included in the study. The patients with at least 1 pulp stone on panoramic radiographs recorded as the “pulp stone group” while patients without any pulp stones were the “control group”. Demographic data and serum levels of calcium, PTH, vitamin D, and uric acid were retrospectively evaluated in both groups. Student t-test or Mann-Whitney U test was used to evaluate the differences between the groups.
ResultsAmong 151 patients, dental pulp stone was detected in 53.6% of patients, and 82.7% of these patients were female. Female sex and pulp stone formation were significantly associated (p = 0.001). The mean age of the pulp stone group was 43.9, while it was 39.9 in the control group, without any significant correlation between age and pulp stone (p > 0.05). Similarly, there were no significant differences in serum levels of PTH, vitamin D, uric acid and calcium between groups (p > 0.05).
ConclusionsAccording to the present study, the effect of dental factors rather than systemic factors should be considered primarily in pulp stone formation.
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- A novel deep learning-based pipeline architecture for pulp stone detection on panoramic radiographs
Ceyda Gürhan, Hasan Yiğit, Selim Yılmaz, Cihat Çetinkaya
Oral Radiology.2025; 41(2): 285. CrossRef - Vitamin D deficiency and oral health: a systematic review of literature
Saida Ziada, Aws Wishahe, Najet Mabrouk, Souad Sahtout
BMC Oral Health.2025;[Epub] CrossRef - Association between pulp stones and systemic diseases: a retrospective study using digital panoramic radiographs in a Turkish population
Buket Beytaş Alğan, Mustafa Murat Koçak, Sibel Koçak, Baran Can Sağlam
BMC Oral Health.2025;[Epub] CrossRef
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Bibliometric analysis of the GentleWave system: trends, collaborations, and research gaps
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Raimundo Sales de Oliveira Neto, Thais de Moraes Souza, João Vitor Oliveira de Amorim, Thaine Oliveira Lima, Guilherme Ferreira da Silva, Rodrigo Ricci Vivan, Murilo Priori Alcalde, Marco Antonio Hungaro Duarte
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Restor Dent Endod 2025;50(2):e17. Published online May 12, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e17
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Abstract
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Supplementary Material
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- Objectives
The study aimed to conduct a bibliometric analysis of the GentleWave system (Sonendo, Inc.).
Methods
An electronic search was conducted in June 2024 using the Web of Science Collection database. Two reviewers independently screened publications, extracting data on authorship, publication details, study design, and citation metrics. Statistical analyses were performed in R to assess variable correlations, while the VOSviewer (Visualization of Similarities Viewer) software was used to map author and keyword networks.
Results
The search yielded 47 records, with 32 studies included. Publications spanned 2014 to 2024. The Journal of Endodontics published the highest number of studies (n = 15), and the International Endodontic Journal had the highest impact factor (5.4). The University of British Columbia and Sonendo, Inc. were the most frequent affiliations. Among the 32 articles, 28 were in vitro studies, primarily focusing on microbiology (n = 9). A total of 95 authors were identified, with Haapasalo and Shen being the most cited (n = 229). The articles accumulated 495 citations, demonstrating a strong positive correlation between the number of studies and citation counts (r = 0.98).
Conclusions
The analysis highlights a predominance of in vitro studies. Geographic concentration in the United States and Canada limits diversity, while the strong correlation between study numbers and citations suggests that increased publication volume enhances visibility.
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- Three-year Outcomes of Conventional Versus Minimally Invasive Endodontic Treatment Protocols: A Retrospective Study
Kiavash Hossini, He Liu, Ya Shen, Jolanta Aleksejuniene, Fahda Algahtani, Ahmed Hieawy
Journal of Endodontics.2025;[Epub] CrossRef
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3,272
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Dentin thickness of C-shaped root canal walls in mandibular premolars based on cone-beam computed tomography: a retrospective cross-sectional study
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Elif Aslan, Ali Canberk Ulusoy, Bilge Hakan Sen, B. Guniz Baksi, Erinc Onem, Ali Mert
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Restor Dent Endod 2025;50(2):e18. Published online May 15, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e18
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Abstract
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- Objectives
This study aimed to measure the dentin thickness of C-shaped canals in mandibular first and second premolars at coronal, middle, and apical root levels using cone-beam computed tomography (CBCT).
Methods
Dentin thicknesses of buccal, lingual, mesial, and distal root walls of 41 C-shaped premolars were measured at three different root levels on axial CBCT slices. The measurements were made at the midpoint of each third, along with 1 mm below and above the midpoint. C-shape configurations of the premolar root canals were also recorded. Analysis of variance, Kruskal-Wallis, and the independent samples t-tests were used for the comparisons (p = 0.05).
Results
The thickest walls for both premolars were buccal and lingual walls at all three root levels (p < 0.05). The thinnest walls for the first premolar teeth were mesial and distal walls of the lingual canal, while it was the mesial end of the buccal and lingual canals for the second premolars (p < 0.05). Dentin wall thicknesses at the mesial end of buccal and lingual canals of C1-shaped first premolars were thinner than C2-shaped first premolars at the apical level (p < 0.05).
Conclusions
Danger zones for C-shaped mandibular first and second premolars are predominantly mesial walls facing the radicular groove and distal wall of the lingual canal. CBCT imaging during endodontic treatment is recommended to avoid complications.
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Citations
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- Anatomical complexity in mandibular second molars: prevalence of C-shaped canals, radicular grooves, taurodontism, and radices molarum in Saudi population
Ahmed A. Madfa, Abdullah F. Alshammari, Eyad Almagadawyi, Ebtsam A. Aledaili, Afaf Al-Haddad
Scientific Reports.2025;[Epub] CrossRef
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3,248
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Endodontic characteristics of mandibular premolar with dens evaginatus: a retrospective study
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Minjin Kim, Sujin Jeon, Min-Seock Seo
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Restor Dent Endod 2024;49(3):e28. Published online July 11, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e28
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This study aimed to investigate the endodontic characteristics of mandibular premolars with dens evaginatus (DE) that require endodontic treatment.
Materials and MethodsPatients who underwent endodontic treatment were enrolled. The inclusion criteria were patients who underwent root canal treatment in the lower permanent teeth with DE and were followed up for at least 1 year. Preoperative clinical and radiographic variables were obtained. The frequency distribution of the preoperative variables was compared using the χ2 or Fisher’s exact tests. The significance of the change in periapical health index (PAI) and root development stages before and after treatment was examined using the Wilcoxon signed-rank test.
ResultsA total of 150 teeth of 134 patients with an average age of 15.3 years were included. The percentage distribution comparison of the preoperative variables and obturation techniques revealed significant differences in pulpal and periapical diagnosis, and percussion, and especially regarding age, root development stage, and PAI. Age was the only statistically significant preoperative variable associated with root growth (p < 0.05).
ConclusionsApproximately, 60% of DEs requiring endodontic treatment had immature roots. Age being the most significant predisposing factor, early treatment provides the greatest opportunity for full root development.
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- A tooth with multiple supernumerary cusps and taurodontism concurrently accompanied with other taurodont teeth: a rare case report
Zihui Tang, Hongchen Zhang, Rongrong Dang, Qiushi Zhang, Yan Huang, Yanwei Yang
Surgical and Radiologic Anatomy.2025;[Epub] CrossRef
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3,108
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Histological evaluation of pulp response to alendronate and Biodentine as pulp capping agents: an animal study
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Thangavel Boopathi, Sekar Manimaran, Joseline Charles Kerena, Mathew Sebeena, Kumaravadivel Karthick, Natesan Thangaraj Deepa
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Restor Dent Endod 2024;49(4):e39. Published online October 29, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e39
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This study aimed to comparatively assess the histological response of the pulp toward alendronate and Biodentine in a direct pulp capping procedure.
Materials and MethodsTwenty-four anterior teeth from 6 New Zealand rabbits were used in this study. Firstly, all rabbits were anesthetized according to their weight. Class V cavities were prepared on the buccal surfaces of anterior teeth. A pin-point exposure of the pulp was then made using a small, sterile round carbide bur and bleeding was arrested with a saline-soaked, sterile cotton pellet. The teeth under study were divided into 2 groups (n = 12). The intentionally exposed pulp was capped with alendronate (Group 1) and Biodentine (Group 2), correspondingly. After 30 days, all rabbits were euthanized; the teeth under study were extracted and taken up for histological analysis.
ResultsBiodentine showed an intact, very dense dentin bridge formation with a uniform odontoblast (OD) layer pattern and mild or absent inflammatory response whereas specimens capped with alendronate demonstrated a dense dentin bridge formation with non-uniform OD layer pattern and mild to moderate inflammatory response.
ConclusionsBiodentine showed more biocompatibility than alendronate. However, alendronate can initiate reparative dentin formation and may be used as an alternative pulp capping agent.
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- In Vivo Evaluation of NF-κB and TGFβ-1 Modulation by Anadara granosa Shell-Derived Calcium Carbonate Bioceramic in Rat Model
Randy Nugraha Pratama, Nurhayati Natsir, Kezia Rachellea Mustakim, Juni Jekti Nugroho
European Journal of General Dentistry.2026;[Epub] CrossRef
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3,091
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Predictive factors in the retrieval of endodontic instruments: the relationship between the fragment length and location
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Ricardo Portigliatti, Eugenia Pilar Consoli Lizzi, Pablo Alejandro Rodríguez
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Restor Dent Endod 2024;49(4):e35. Published online September 9, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e35
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This study aimed to relate the file fragment length and location in the root canal to the retrieval chances, the clinical time required and the occurrence of secondary fractures.
Materials and MethodsSixty clinical cases of fractured instruments were included in this study. They were classified according to the instrument length and the location of the root canal. In each group, the success rate in the instrument retrieval, the clinical time required and the occurrence of secondary fractures were evaluated. The collected data were analyzed using the Kruskal-Wallis test on the basis of a 0.05 significance level.
ResultsThe fragment length showed no significant influence on the assessed variables (p > 0.05). The root third where the instrument was located resulted in an increased clinical time, with statistically significant differences (p < 0.05). However, the procedure success rate and the occurrence of secondary fractures showed no association with these variables.
ConclusionsIn accordance with the findings of this study, the fractured fragment length did not influence any of the variables assessed, but it is suggested to focus on the fragment location inside the root canal to decide the retrieval of a fractured instrument.
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Citations
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- Neodymium-Doped Yttrium Aluminum Perovskite (Nd:YAP) Laser in the Elimination of Endodontic Nickel-Titanium Files Fractured in Rooted Canals (Part 2: Teeth With Significant Root Curvature)
Amaury Namour, Marwan El Mobadder, Clément Cerfontaine, Patrick Matamba, Lucia Misoaga, Delphine Magnin , Praveen Arany, Samir Nammour
Cureus.2025;[Epub] CrossRef
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3,051
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Comparative study of the effectiveness of different bleaching agents on blood-colored extracted teeth and investigation of recoloring after bleaching: an in vitro experimental study
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Gülşen Arslan, Akın Aladağ, Ayşegül Demirbaş, Murat Türkün
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Restor Dent Endod 2025;50(3):e22. Published online July 9, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e22
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PDF
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- Objectives
This study evaluated the efficacy of three distinct bleaching agents over time on blood-stained, devitalized teeth. Furthermore, the recoloring subsequent to bleaching will be monitored.
Methods
The study was conducted on 60 caries-free, unfilled, upper human incisors. The Freccia and Peters blood staining technique was employed, and four groups (n = 15) were identified: control, 35% hydrogen peroxide-treated, 37% carbamide peroxide-treated, and sodium perborate-treated groups. Color differences were measured using ΔE00, ΔWID, L*, a*, and b* values. To investigate tooth discoloration after bleaching, 10 unbleached teeth with three groups of 10 bleached teeth were compared by vine staining. The group of bleached teeth was restored immediately, another group waited one week, and the third group had sodium ascorbate applied and analyzed using one-way analysis of variance tests (p < 0.05).
Results
Among the groups, carbamide peroxide exhibited the most significant whitening during the 6-day bleaching process, followed by hydrogen peroxide and sodium perborate. Subsequent examination of the wine recoloring of post-bleaching samples demonstrated that bleached teeth exhibited a heightened propensity for recoloration in contrast to unbleached teeth. Notably, sodium ascorbate treatments for hydrogen peroxide neutralization and the wait-and-restore approach were not statistically significant in terms of preventing recoloration.
Conclusions
Sodium perborate is less effective and more time-consuming than hydrogen peroxide or carbamide peroxide for bleaching purposes. Carbamide peroxide is the most effective bleaching agent. The sodium ascorbate treatment and the wait-and-restore approach are ineffective in preventing recoloring. Bleached teeth have more discoloration than unbleached teeth.
Case Report
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An unusual case of dens invaginatus on a mandibular second molar: a case report
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Davide Mancino, Dina Abdellatif, Alfredo Iandolo, Fabien Bornert, Youssef Haïkel
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Restor Dent Endod 2025;50(1):e2. Published online January 8, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e2
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- The present case report describes the endodontic treatment of a type III B dens invaginatus (DI) in a three-rooted mandibular second molar since the invagination invades the root and extends apically. Clinical and cone-beam computed tomography examination of the mandibular second molar showed a broadened coronal morphology, DI, a third root, periapical radiolucency, and compression of a distal root canal by the invagination, which developed an atypical semilunar shape. The tooth was diagnosed with pulpal necrosis, symptomatic apical, and peri-invagination periodontitis. Consequently, three-dimensional virtual reconstruction was conducted to improve anatomical interpretation and case planning and accelerate the intraoperative phase by reducing operator stress and minimizing intraoperative variables. The present case report aims to raise awareness of the existence of DI on the mandibular second molar.
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Citations
Citations to this article as recorded by

- Dens Invaginatus—Mandibular Second Molar—Case Report
Krystyna Pietrzycka, Natalia Lutomska, Cornelis H. Pameijer, Monika Lukomska-Szymanska
Dentistry Journal.2026; 14(1): 27. CrossRef - Type IIIb dens invaginatus in a maxillary second molar and its microscopic anatomical features: a case report
Mingming Li, Zhiwu Wu, Shaoying Duan, Yuling Zuo
BMC Oral Health.2025;[Epub] CrossRef
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Research Articles
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Prevalence of salivary microbial load and lactic acid presence in diabetic and non-diabetic individuals with different dental caries stages
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Monika Mohanty, Shashirekha Govind, Shakti Rath
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Restor Dent Endod 2024;49(1):e4. Published online January 12, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e4
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- Objectives
This study aims to correlate caries-causing microorganism load, lactic acid estimation, and blood groups to high caries risk in diabetic and non-diabetic individuals and low caries risk in healthy individuals.
Materials and MethodsThis study includes 30 participants divided into 3 groups: Group A, High-risk caries diabetic individuals; Group B, High-risk caries non-diabetic individuals; and Group C, Low-risk caries individuals. The medical condition, oral hygiene, and caries risk assessment (American Dental Association classification and International Caries Detection and Assessment System scoring) were documented. Each individual’s 3 mL of saliva was analyzed for microbial load and lactic acid as follows: Part I: 2 mL for microbial quantity estimation using nutrient agar and blood agar medium, biochemical investigation, and carbohydrate fermentation tests; Part II: 0.5 mL for lactic acid estimation using spectrophotometric analysis. Among the selected individuals, blood group correlation was assessed. The χ2 test, Kruskal-Wallis test, and post hoc analysis were done using Dunn’s test (p < 0.05).
ResultsGroup A had the highest microbial load and lactic acid concentration, followed by Groups B and C. The predominant bacteria were Lactobacilli (63.00 ± 15.49) and Streptococcus mutans (76.00 ± 13.90) in saliva. Blood Group B is prevalent in diabetic and non-diabetic high-risk caries patients but statistically insignificant.
ConclusionsDiabetic individuals are more susceptible to dental caries due to high microbial loads and increased lactic acid production. These factors also lower the executing tendency of neutrophils, which accelerates microbial accumulation and increases the risk of caries in diabetic individuals.
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Citations
Citations to this article as recorded by

- Oral Health Disparities in Type 2 Diabetes: Examining the Elevated Risk for Dental Caries—A Comparative Study
José Frias-Bulhosa, Maria Conceição Manso, Carla Lopes Mota, Paulo Melo
Dentistry Journal.2025; 13(6): 258. CrossRef - Exploring the photosensitizing potential of Nanoliposome Loaded Improved Toluidine Blue O (NLITBO) Against Streptococcus mutans: An in-vitro feasibility study
Swagatika Panda, Lipsa Rout, Neeta Mohanty, Anurag Satpathy, Bhabani Sankar Satapathy, Shakti Rath, Divya Gopinath, Geelsu Hwang
PLOS ONE.2024; 19(10): e0312521. CrossRef - Altered salivary microbiota associated with high-sugar beverage consumption
Xiaozhou Fan, Kelsey R. Monson, Brandilyn A. Peters, Jennifer M. Whittington, Caroline Y. Um, Paul E. Oberstein, Marjorie L. McCullough, Neal D. Freedman, Wen-Yi Huang, Jiyoung Ahn, Richard B. Hayes
Scientific Reports.2024;[Epub] CrossRef
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Shaping ability and cyclic fatigue resistance between Genius ProFlex, ZenFlex, and TruNatomy rotary systems: an experimental study
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Raimundo Sales de Oliveira Neto, Murilo Priori Alcalde, Pedro Cesar Gomes Titato, Pedro Henrique Souza Calefi, Carlos Alberto Spironelli Ramos, Guilherme Ferreira da Silva, Rodrigo Ricci Vivan, Marco Antonio Hungaro Duarte
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Restor Dent Endod 2025;50(1):e9. Published online February 13, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e9
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- Objectives
The aim of this study was to investigate the efficacy of three newly introduced rotary endodontic systems: Genius ProFlex (Medidenta), TruNatomy (Dentsply Maillefer), and ZenFlex (Kerr).
Methods
Forty-five mandibular molars with root canal curvatures <5° were utilized. Micro-computed tomography scans were performed pre- and post-preparation to assess apical transportation, centralization, percentage of dentin wear, and canal volume alterations. Eight instruments of each diameter underwent cyclic fatigue testing.
Results
The percentage of dentin wear on mesial and distal walls showed no significant differences among ZenFlex, TruNatomy, and Genius ProFlex at 1, 2, 3, and 4 mm from the apical foramen and root canal orifice (p > 0.05). Centering ability varied in the mesiolingual canal (p < 0.05). No notable differences were observed in transportation (p > 0.05). Genius ProFlex demonstrated lower volumetric changes (p < 0.05). There were significant differences in cyclic fatigue, with higher values for Genius ProFlex and lower values for TruNatomy (p < 0.05).
Conclusions
The three nickel-titanium rotary instruments are safe and efficient for root canal preparation, with Genius ProFlex exhibiting superior cyclic fatigue resistance.
Case Report
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Multidisciplinary management of an endo-perio lesion complicated by a cemental tear: a case report
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Nishanth D. Sadhak, Akshaya Pallod, Shreyas Oza
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Restor Dent Endod 2025;50(3):e31. Published online August 22, 2025
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DOI: https://doi.org/10.5395/rde.2025.50.e31
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- Endodontic-periodontal lesions (EPLs) complicated by cemental tears present a diagnostic and therapeutic challenge. This case report describes the successful management of a 66-year-old male patient with a mandibular second molar (#18) exhibiting an EPL complicated by a cemental tear. Clinical examination revealed a draining sinus tract, deep periodontal pockets, and radiographic evidence of a “J-shaped” lesion and a radiopaque cemental fragment. The tooth had previously initiated endodontic treatment. A multidisciplinary approach involving endodontic treatment and surgical removal of the cemental tear was implemented. At 24-month follow-up, clinical and radiographic examination revealed significant improvement in periodontal health, bone regeneration, and resolution of the lesion. This case highlights the importance of considering cemental tears in the differential diagnosis of EPLs and demonstrates the efficacy of a combined endodontic-periodontal approach for achieving predictable outcomes.
Research Articles
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Fracture resistance after root canal filling removal using ProTaper Next, ProTaper Universal Retreatment or hybrid instrumentation: an ex vivo study
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Hadeel Hassan Hanafy, Marwa Mahmoud Bedier, Suzan Abdul Wanees Amin
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Restor Dent Endod 2024;49(4):e38. Published online October 11, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e38
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This study evaluated the effect of ProTaper Next (PTN), ProTaper Universal Retreatment (PTR) and hybrid instrumentation (HI) for canal filling removal on the fracture resistance (FR), mode of failure (MoF), and filling removal time.
Materials and MethodsNinety-six, mandibular premolars were decoronated and randomly divided into 6 groups (n = 16), as follows: sound (S), untreated canals; prepared teeth (P), canals only prepared to ProTaper Universal finishing instrument (F4); endodontically-treated (ET), prepared and obturated canals using the single-cone technique; and groups PTN, PTR, and HI where filling was removed using PTN, PTR, or HI respectively. FR under vertical loading; MoF and time were assessed. Data were analyzed (Significance level [α] = 0.05).
ResultsThere was a significant difference in FR among all groups (p < 0.001) (HI < P < PTN < S < ET < PTR). HI showed lower FR than S, ET and PTR, and P showed lower FR than PTR (p < 0.05). For experimental groups, there was a significant difference between every group pair (p < 0.05) No significant difference was found regarding MoF distribution (p > 0.05). HI required the highest filling removal time, while PTR required the least (p < 0.05 between every group pair).
ConclusionsThe effect of filling removal on FR may depend on the filling removal technique/system used. PTR could be faster and protect against fracture followed by PTN; HI could adversely affect FR. FR may be associated with filling removal time.
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Assessment of mechanical allodynia in healthy teeth adjacent and contralateral to endodontically diseased teeth: a clinical study
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Vaishnavi Ratnakar Patankar, Ashish K Jain, Rahul D Rao, Prajakta R Rao
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Restor Dent Endod 2024;49(3):e31. Published online July 29, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e31
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The present study investigated the prevalence of mechanical allodynia (MA) in healthy teeth adjacent and contralateral to endodontically diseased teeth.
Materials and MethodsThis cross-sectional study included 114 patients with symptomatic irreversible pulpitis and apical periodontitis in permanent mandibular first molars who possessed healthy teeth adjacent and contralateral to the endodontically diseased tooth. The mechanical sensitivity of the teeth was determined by percussion testing. The presence or absence of pain on percussion in the teeth adjacent and contralateral to the endodontically diseased tooth and the tooth distal to the contralateral symmetrical tooth was recorded according to coding criteria. The prevalence of MA was computed as a percentage, and binary logistic regression analysis was done. The Fisher exact test and Mann-Whitney U test were used for binary and ordinal data.
ResultsAge and sex did not influence the prevalence of MA. An increased prevalence of MA was found in patients with higher levels of spontaneous pain (p < 0.001). The prevalence of allodynia was 57% in teeth adjacent to endodontically diseased teeth and 10.5% in teeth contralateral to endodontically diseased teeth. In addition, on the ipsilateral side, there were more painful sensations distal to the diseased tooth than mesially.
ConclusionsDespite being disease-free, teeth adjacent and contralateral to endodontically diseased teeth exhibited pain on percussion. There was a direct association between the severity of the patient’s pain and the presence of MA.
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Procedural errors detected by cone beam tomography in cases with indication for retreatment: in vivo cross-sectional study
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Henry Paul Valverde Haro, Carmen Rosa Garcia Rupaya, Flávio R. F. Alves
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Restor Dent Endod 2024;49(3):e26. Published online June 24, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e26
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This study aimed to investigate the frequency and type of endodontic procedural errors in cases indicated for retreatment through cone-beam computed tomography (CBCT) analysis.
Materials and MethodsThe sample consisted of 96 CBCT scans, encompassing 122 permanent teeth with fully formed roots. Errors included perforation, instrument fracture, canal transportation, missed canals, and inadequate apical limit of filling. Additionally, potential risk factors were analyzed and subjected to statistical modeling.
ResultsThe most frequent procedural error observed was the inadequate apical limit of filling, followed by canal transportation, perforation, missed canal, and instrument fracture. Statistically significant associations were identified between various procedural errors and specific factors. These include canal transportation and root canal wall, with the buccal wall being the most commonly affected; missed canal and tooth type, particularly the palatine and second mesiobuccal canal canals; inadequate apical limit of filling and root curvature, showing a higher deviation to the mesial direction in severely curved canals; inadequate apical limit of filling and the presence of calcifications, with underfilling being the most frequent; canal transportation and periapical lesion, notably with deviation to the buccal direction; and the direction of perforation and periapical lesion, most frequently occurring to buccal direction.
ConclusionsCBCT emerges as a valuable tool in identifying procedural errors and associated factors, crucial for their prevention and management.
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Citations
Citations to this article as recorded by

- Repair of furcal perforations using different calcium silicate cements: An in vitro study
Ariana Esperanza Apolo Aguilar, Maria Soledad Peñaherrera Manosalvas, Henry Paul Valverde Haro
Journal of Conservative Dentistry and Endodontics.2025; 28(10): 1007. CrossRef - Impact of Downward Load and Rotational Kinematics on Root Canal Instrumentation with a Heat-Treated Nickel–Titanium Rotary Instrument
Risako Yamamoto, Keiichiro Maki, Shunsuke Kimura, Satoshi Omori, Keiko Hirano, Arata Ebihara, Yoshio Yahata, Takashi Okiji
Materials.2025; 19(1): 108. CrossRef - ANALYSIS OF THE QUALITY OF ROOT CANAL OBTURATION AND PREVALENCE OF APICAL PERIODONTITIS IN ENDODONTICALLY TREATED TEETH
Cristina Coralia Nistor, Ioana Suciu , Elena Zabrac , Ruxandra Ioana Bartok , Bogdan Dimitriu , Andreea Baluta
Romanian Journal of Oral Rehabilitation.2024; 16(4): 311. CrossRef
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YouTube as a source of information about rubber dam: quality and content analysis
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Gülsen Kiraz, Arzu Kaya Mumcu, Safa Kurnaz
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Restor Dent Endod 2024;49(1):e10. Published online February 5, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e10
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This study aimed to evaluate the content, quality and demographics of YouTube videos about rubber dam as an information source for clinicians and dental students.
Materials and Methods“Rubber dam,” “rubber dam application,” “dental isolation,” “rubber dam isolation,” and “dental dam” were determined as keywords for the detection of YouTube videos related to rubber dam. Seventy 3 videos were evaluated and a total of 34 videos met the inclusion criteria. All selected videos were evaluated according to 8 parameters. The videos were scored 1 if the videos contained information about the selected parameter, but if the videos did not contain enough information, they were scored 0. The data were statistically analyzed with the analysis of variance and post hoc Tukey test (p < 0.05).
ResultsWe found that 41% of the videos have poor, 47% have moderate, and 12% have good information. There is a statistically significant difference in time between poor and good information content (p < 0.05). There is a statistically significant difference between the poor and good information in the video information and quality index 1.
ConclusionsRubber dam-related videos available on YouTube are generally moderately informed and insufficient. YouTube is currently not sufficient as a source of information for patients and clinicians at the moment. The YouTube platform should be developed and enriched with quality information on current and dental issues.
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Citations
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- Assessing the Quality of YouTube® Videos on Nitrous Oxide/Oxygen Inhalation: A Multi-Dimensional Approach for Pediatric Dentists
Sanaa N. Al-Haj Ali, Nehal AlHarbi, Hessah H. Almutairi
Pesquisa Brasileira em Odontopediatria e Clínica Integrada.2025;[Epub] CrossRef - Assessing the reliability and educational value of YouTube videos on computer-controlled local anesthesia in dentistry
Hulya Cerci Akcay, Erdal Cem Kargu, Nefise Seker, Tanay Chaubal
PLOS One.2025; 20(8): e0329291. CrossRef - Evaluation of Endodontic Retreatment Videos on The Youtube Platform: Quality and Content Analysis
Birgül Özaşır, Tufan Özaşır, Derin Buğu Yüzer, Deniz İmamoğlu, Kamran Gülşahı
European Annals of Dental Sciences.2025; 52(2): 103. CrossRef - Assessing the usefulness of educational videos on endodontic irrigation for dental students: a pilot study
Jin Wey Kock, Shahmin Kar Sze Yeap, Naveen Chhabra, Philip Yuan-Ho Chien, Shekhar Bhatia
BMC Medical Education.2025;[Epub] CrossRef
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Effect of surface sealant on the color stability and whiteness index of single-shade resin composites after staining and bleaching
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Muhammet Fidan, Özhan Yağcı
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Restor Dent Endod 2024;49(3):e30. Published online July 11, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e30
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The aim of the current study was to evaluate the effect of polishing systems and surface sealant on the color stability and whiteness index of single-shade resin composites after staining and bleaching.
Materials and MethodsThree single-shade (Omnichroma, Charisma Diamond One, Zenchroma) and one multi-shade (Filtek Z250) materials were tested. From each resin composite, 40 specimens were prepared. The specimens were divided into 4 subgroups (n = 10) according to the surface treatments: 1-step polishing, 1-step + Biscover LV, 2-step polishing, and 2-step polishing + Biscover LV. Color differences (ΔE00) were calculated after being immersed in the coffee solution for 12 days. After the staining, the specimens were immersed in a whitening mouthrinse (Crest-3D White) for 12 hours. Whiteness index differences (∆WID = WID after staining − WID after bleaching) values were recorded. The generalized linear model was used for analysis (p < 0.05).
ResultsThe lowest and highest ΔE00 values were found for Zenchroma and Charisma Diamond One respectively. Sealed groups indicated higher ΔE00 values than nonsealed groups with significant differences (p = 0.008). The lowest and highest ΔWID values were found for Zenchroma and Charisma Diamond One respectively. Sealed groups indicated lower ΔWID values than nonsealed groups with significant differences (p = 0.022).
ConclusionsThe use of surface sealant increased the discoloration and showed less whiteness change in resin materials. When the 1-step was compared with the 2-step polishing, the effects on the color stability and whiteness index values of the resin materials were similar.
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- Evaluating the effects of bleaching on color stability and surface roughness in single-shade and multi-shade resin composites
Hatice Tepe, Özge Çeliksöz, Zeynep Biçer, Batucan Yaman
Anatolian Current Medical Journal.2024; 6(6): 372. CrossRef
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Color stability and solubility of Biodentine and NeoPutty in contact with different irrigation solutions
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Sıla Nur Usta, Cangül Keskin
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Restor Dent Endod 2024;49(3):e25. Published online June 19, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e25
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Abstract
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This study aimed to evaluate the color stability and solubility of Biodentine and NeoPutty in contact with different irrigation solutions.
Materials and MethodsBiodentine and NeoPutty were set in cylindrical molds with 7 mm diameter and 1.5 mm high and immersed in distilled water, 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), 9% 1-hydroxyethylidene 1,1-diphosphonate (HEDP), and 5% sodium hypochlorite (NaOCl) solutions for 24 hours. The color change was measured with a spectrophotometer. The solubility values were calculated as the mass loss was expressed as a percentage of the original mass using an analytical balance with 10−4 g accuracy. Data were analyzed with Kruskal-Wallis followed by Mann-Whitney U tests, and 2-way analysis of variance test followed by Bonferroni corrections for pairwise comparisons for solubility and color stability with a 5% significance threshold, respectively.
ResultsBiodentine exhibited higher color changes compared to the NeoPutty contact with all solutions except distilled water (p < 0.05). Both hydraulic cements (HCs) showed higher discoloration values immersion in CHX followed by NaOCl. No statistically significant difference was found between Biodentine and NeoPutty regardless of irrigation solution in terms of solubility (p > 0.05). Solubility values were lower in the distilled water group compared to EDTA and CHX (p < 0.05).
ConclusionsTested HCs showed solubility and color changes at various rates. NeoPutty could be an appropriate material in aesthetic areas. The usage of HEDP as an irrigant solution can be considered suitable for various endodontic treatments due to its relatively lower solubility and discoloration values.
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Physical-mechanical, chemical and biological properties of graphene-reinforced glass ionomer cements
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Tatiane Ramos dos Santos Jordão, Laura Soares Viana Fernandes, Karla Lorene de França Leite, Adílis Alexandria, Emmanuel João Nogueira Leal Silva, Lucianne Cople Maia, Tatiana Kelly da Silva Fidalgo
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Restor Dent Endod 2024;49(4):e37. Published online October 10, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e37
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This study aimed to evaluate the physical-mechanical, chemical, and biological properties of graphene-reinforced glass ionomer cements (GICs).
Materials and MethodsDifferent proportions of graphene powder were incorporated into 2 high-viscosity self-curing GIC, Ketac Molar (GKetac) and Fuji IX (GFuji), in 4 different concentrations: 0.5%, 1%, 2%, and 5%. The control groups included the GICs without graphene. Experiments were performed to analyze linear (Ra) and volumetric roughness (Sa), antimicrobial activity, radiopacity, fluoride release, microhardness, solubility, and water sorption. Data were analyzed using Kruskal-Wallis, Mann-Whitney, Wilcoxon, analysis of variance, and Tukey’s test (p ≤ 0.05).
ResultsThe GKetac 0% and GFuji0% groups presented higher Ra (4.05 and 2.72) and Sa (4.76 and 5.16), respectively. No inhibition zone was observed, and the incorporation of graphene reduced radiopacity. Moreover, there was no influence on the solubility and water sorption after 21 days. A greater fluoride release was observed in the period of 7 days for most of the groups. After 21 days, GKetac 5%, 2%, and 1% presented higher releasing than 0% and 0.5% (p ≤ 0.05).
ConclusionsThe graphene incorporation improved the microhardness of GICs in lower concentrations. Graphene incorporation to GICs modified some physical-mechanical, and chemical, but not affected biological properties.
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- Laboratory-Based Additive Modifications in Glass Ionomer Cements: A Scoping Review Using a Systematic Data Mining and Trend Analysis Framework (2015-2024)
Kenta Tsuchiya, Sharanbir K Sidhu, Salvatore Sauro, Jukka P. Matinlinna, Hidehiko Sano, Monica Yamauti, Shuhei Hoshika, James Kit Hon Tsoi, Atsushi Tomokiyo
Journal of Dentistry.2026; : 106349. CrossRef
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Effect of Dental Practicality Index training using an online video on decision-making and confidence level in treatment planning by dental undergraduates
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Zhai Wei See, Ming Sern Lee, Abhishek Parolia, Shalini Kanagasingam, Shilpa Gunjal, Shanon Patel
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Restor Dent Endod 2024;49(1):e8. Published online January 24, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e8
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The purpose of this study was to evaluate the effect of Dental Practicality Index (DPI) training using an online video on the treatment planning decisions and confidence level of dental undergraduates (DUs).
Materials and MethodsNinety-four DUs were shown 15 clinical case scenarios and asked to decide on treatment plans based on 4 treatment options. The most appropriate treatment plan had been decided by a consensus panel of experienced dentists. DUs then underwent DPI training using an online video. In a post-DPI-training test, DUs were shown the same clinical case scenarios and asked to assign the best treatment option. After 6 weeks, DUs were retested to assess their knowledge retention. In all 3 tests, DUs completed the confidence level scale questionnaire. Data were analyzed using the related-samples Wilcoxon signed rank test and the independent-samples Mann-Whitney U test with the level of significance set at p < 0.05.
ResultsDPI training significantly improved the mean scores of the DUs from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training.
ConclusionsTraining DUs using DPI with an online video improved their decision-making and confidence level in treatment planning.
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- STUDY OF THE EFFECTIVENESS OF THE USE OF DIRECT AND INDIRECT RESTORATION OVER TIME IN THE TREATMENT OF DEFECTS OF HARD DENTAL TISSUES AFTER ENDODONTIC INTERVENTION
V. V. Fedoriuk, М. М. Rozhko
Art of Medicine.2025; : 94. CrossRef
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2,545
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Evaluation of mineral induction ability and cytotoxicity of carbonated hydroxyapatite for pulp tissue regeneration: an in vitro study
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S. Swathi Priyadharshini, Chinnasamy Ragavendran, Anand Sherwood, J. Ramana Ramya, Jogikalmat Krithikadatta
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Restor Dent Endod 2024;49(4):e40. Published online October 29, 2024
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DOI: https://doi.org/10.5395/rde.2024.49.e40
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This study aimed to evaluate carbonated hydroxyapatite (CHA)’s ability for mineral induction and its in vitro cytotoxicity with human dental pulp cells.
Materials and MethodsPrecursors for the study include di-ammonium hydrogen phosphate and calcium nitrate tetrahydrate, with sodium hydrogen carbonate added to achieve different levels of carbonate substitution. The synthesized CHA samples are characterized using X-ray diffraction, Fourier transform infrared spectroscopy, and Raman spectroscopy. Scanning electron microscopy (SEM) was used to observe morphology. For 14 days at 37°C, samples were submerged in simulated body fluid to assess their mineral induction capabilities. SEM was used to confirm apatite formation on sample surfaces. The cytotoxicity assay was used to assess the vitality of the cells following their exposure to various concentrations of CHA.
ResultsThe Joint Committee on Powder Diffraction Standards data for HA aligned well with the results from X-ray diffraction analysis of CHA across 3 different concentrations, indicating strong agreement. Fourier transform infrared spectra indicated the presence of phosphate, hydroxyl, and carbonate groups within the samples. SEM and Energy-dispersive X-ray analysis show agglomerated and flaky nanoparticles. All the samples are bioactive, but the formation of apatite differs from one another. In vitro cytotoxicity assay showed that over 70% of cells maintain viability.
ConclusionsThe results of this study may provide insight into the potential use of carbonated HA as a dental pulp-capping material for vital pulp therapy.
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- Comparative evaluation of compressive strength and morphological interface of carbonated hydroxyapatite with other pulp capping materials: An in vitro analysis
S. Swathi Priyadharshini, Chinnasamy Ragavendran, I. Anand Sherwood, Ramanaramya Jeyapalan
Endodontology.2025; 37(1): 90. CrossRef - Smart Nanomaterials: Current State and Future Prospects in Drug Delivery and Tissue Engineering
E. Elizabeth Rani, D. Sakthi Sanjana, E. Karthikeyan, J. Nandhini
Biomedical Materials & Devices.2025;[Epub] CrossRef - Thermoresponsive Nanomaterials: Revolutionizing Cancer Theranostics
Bellarmin Michael, Mohanakrishnan Srinivasan, Karthikeyan Elumalai, Lokeshwar Ravikumar, Sivaprakash Kathiresan, Nandhini Jayaprakash
Biomedical Materials & Devices.2025;[Epub] CrossRef - Bioactive Dioxo-Phosphobetaines derived from the reaction of Dichlorodinitrobenzofuroxane with various phosphines
Irina V. Galkina, Haiyan Fan, Semen R. Romanov, Dmitriy I. Bakhtiyarov, Luisa M. Usupova, Svetlana N. Egorova, Yulia V. Bakhtiyarova, Enrico Benassi
Bioorganic Chemistry.2025; 163: 108695. CrossRef - Near-infrared laser-activated PLGA-PDA core-shell nanohybrids for synergistic photothermal antibacterial therapy and sustained ion release in orthodontic white spot lesions prevention
Zezhou Feng, Yujiang Liu, Silu Sun, Minmin Si, Di Huang, Zhiyuan Feng
Journal of Dentistry.2025; 162: 106078. CrossRef - Formation and utilization of soluble microbial products in denitrifying biofilters at different carbon-to-nitrogen ratios: Microbial community characteristics
Fangyuan Jiang, Xianyang Shi
Journal of Environmental Chemical Engineering.2025; 13(6): 119554. CrossRef - Bioactivity and biocompatibility of bioceramic-based pulp capping materials in laboratory and animal models
Rafiqul Islam, Md. Refat Readul Islam, Kenta Tsuchiya, Yu Toida, Hidehiko Sano, Monica Yamauti, Hany Mohamed Aly Ahmed, Atsushi Tomokiyo
Journal of Materials Science: Materials in Medicine.2025;[Epub] CrossRef - Physical, Chemical, and Biological Properties of Graphene Nanoparticle-added Tricalcium Silicate Formulations: A Systematic Review
Soundaria Srinivasan, Deepa Gurunathan, Lakshmi Thangavelu
Journal of International Oral Health.2025;[Epub] CrossRef - Advanced structural and compositional profiling of mineral trioxide aggregate incorporated with nano-carbonated hydroxyapatite: a comprehensive X-ray diffraction and energy dispersive X-ray investigation
Njwan Fadhel Shehab, Nadia Hameed Hasan, Alaa Edrees Dawood, Nawal Atiya Khalaf
Biomaterial Investigations in Dentistry.2025; 12: 216. CrossRef
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