Restorative Dentistry & Endodontics

Research Articles

Surface properties and susceptibility to staining of a resin composite after brushing with different whitening toothpastes: Aline da Silva Barros, Carolina Meneghin Barbosa, Renata Siqueira Scatolin, Waldemir Francisco Vieira Junior, Laura Nobre Ferraz; Restor Dent Endod 2025;50(1):e6. Published online February 26, 2025; DOI: https://doi.org/10.5395/rde.2025.50.e6

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This study investigated the effects of different whitening toothpaste (WT) on the surface properties and staining susceptibility of a resin composite.
Methods
Cylindrical samples were prepared with a micro-hybrid resin composite and were randomized into groups according to the toothpaste (n = 12): distilled water (DW), regular toothpaste (RT), WT with silica + pyrophosphate (WT-S/P), WT with pentaphosphate and pyrophosphate (WT-P/P), WT with hydrogen peroxide and pyrophosphate (WT-HP/P) and WT with charcoal and pyrophosphate (WT-Ch/P). The samples were brushed for 825 cycles in an automatic brushing machine, simulating 30 days of brushing. After that, an immersion in coffee (10 mL/sample) was performed for 30 minutes for 30 days. The analyses of color, surface microhardness (SMH), and surface roughness (Ra) were performed at the initial time, after brushing with toothpaste and after immersion in coffee. The ΔL*, Δa*, Δb*, ΔEab, Δand E00 values were calculated comparing after toothpaste with initial time and after coffee with after toothpaste. Data were analyzed using a mixed linear model for repeated measures (SMH), Kruskal-Wallis, Dunn, Friedman, and Nemenyi tests, with α = 0.05.
Results
For ΔL*, the WT-Ch/P group had the lowest values and differed from the other groups comparing the after toothpaste with the initial time interval (p < 0.001). The WT-Ch/P group had the lowest SMH values in after-toothpaste time (p < 0.001). In after-toothpaste time and after coffee time, the WT-S/P group had the highest Ra values and differed from the groups except the WT-Ch/P group (p < 0.001).
Conclusions
The toothpaste composition affects the surface characteristics and susceptibility to staining of the resin composite. The charcoal-based toothpaste had the worst performance for the color analyses and SMH.

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Development of whitening mouth rinses formulated with mushroom residues and their effect on enamel’s physical properties: Julliana Andrade da Silva, Dayse Alexia de Carvalho de Brito, Débora Alves Nunes Leite Lima, Juliano Lemos Bicas, Gislaine Ricci Leonardi; Restor Dent Endod 2024;49(3):e27. Published online June 27, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e27

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This study aimed to develop whitening mouth rinses formulated with industrial mushrooms and compare them with over-the-counter whitening mouth rinses.
Materials and Methods
Formulations with black shimeji mushrooms, mushroom substrates, and mushroom stalks were developed. Bovine enamel/dentin samples were divided into 7 groups (n = 10): Colgate Luminous White, Listerine Whitening Extreme (LWE), Listerine Cool Mint (LC), mushroom extract rinse (MEC), mushroom substrate rinse (MSB), mushroom stalk rinse (MTC), and artificial saliva. Samples were stained with black tea for 6 days, and then were immersed in 100 mL of each mouth rinse twice daily for 14 days. Color parameters (CIELAB [ΔE*], CIEDE2000 [ΔE₀₀], whiteness index for dentistry [ΔWI_D]) and microhardness (Knoop hardness number [KHN]) were analyzed at T₁ (initial), T₂ (24 hours), and T₃ (7 days). Mouth rinse pH was measured, and enamel was examined using a scanning electron microscope. Data were analyzed using generalized linear models, and KHN with the generalized linear mixed model for repeated measures (p ≤ 0.05).
Results
ΔE* was higher in LW and MSB groups. No significant differences were found for ΔE₀₀ (p = 0.0982) and ΔWI_D (p = 0.2536). Experimental mouth rinses did not promote enamel whitening based on ΔE₀₀ and ΔWI_D. LWE and LC reduced KHN and had a more acidic pH, while MEC had higher KHN at T2. MEC, MSB, and MTC had alkaline pH, not altering the tooth surface.
Conclusions
Black shimeji mushrooms are promising for mouth rinse development due to their alkaline pH and non-altering effect on surface microhardness.

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Color stability and solubility of Biodentine and NeoPutty in contact with different irrigation solutions: Sıla Nur Usta, Cangül Keskin; Restor Dent Endod 2024;49(3):e25. Published online June 19, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e25

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This study aimed to evaluate the color stability and solubility of Biodentine and NeoPutty in contact with different irrigation solutions.
Materials and Methods
Biodentine and NeoPutty were set in cylindrical molds with 7 mm diameter and 1.5 mm high and immersed in distilled water, 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), 9% 1-hydroxyethylidene 1,1-diphosphonate (HEDP), and 5% sodium hypochlorite (NaOCl) solutions for 24 hours. The color change was measured with a spectrophotometer. The solubility values were calculated as the mass loss was expressed as a percentage of the original mass using an analytical balance with 10⁻⁴ g accuracy. Data were analyzed with Kruskal-Wallis followed by Mann-Whitney U tests, and 2-way analysis of variance test followed by Bonferroni corrections for pairwise comparisons for solubility and color stability with a 5% significance threshold, respectively.
Results
Biodentine exhibited higher color changes compared to the NeoPutty contact with all solutions except distilled water (p < 0.05). Both hydraulic cements (HCs) showed higher discoloration values immersion in CHX followed by NaOCl. No statistically significant difference was found between Biodentine and NeoPutty regardless of irrigation solution in terms of solubility (p > 0.05). Solubility values were lower in the distilled water group compared to EDTA and CHX (p < 0.05).
Conclusions
Tested HCs showed solubility and color changes at various rates. NeoPutty could be an appropriate material in aesthetic areas. The usage of HEDP as an irrigant solution can be considered suitable for various endodontic treatments due to its relatively lower solubility and discoloration values.

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Can discolored dental composites be bleached in depth?: Luca Giachetti, Daniele Scaminaci Russo, Michele Nieri, Francesca Cinelli; Restor Dent Endod 2024;49(3):e23. Published online June 11, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e23

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Previous in vitro studies determined the whitening effects of bleaching products on stained resin composite surfaces. This in vitro study aimed to verify the effectiveness of a whitening system on composite resin previously subjected to pigmentation, specifically examining the depth of whitening effectiveness within the material structure.
Materials and Methods
A commercially available nano-filled composite resin was used. Specimens were stained using a coffee-based solution and a 10% carbamide peroxide-based gel was employed as the whitening agent. The pigment’s penetration and the effect of the bleaching gel were evaluated by measuring color (CieLab values) from the outer edge to the inner part of the specimens. Color measurements were taken at 14 points, starting from 0.1 mm from the external perimeter up to 3.0 mm.
Results
Analysis of variance tests showed a statistically significant difference between the Control Group (CG), Pigmentation Group, and Whitening Group. The whitening agent was effective up to 1.5 mm in depth, with Whiteness index (W) values not statistically different from those of CG up to 0.5 mm in depth.
Conclusions
Whitening agents on nano-filled resin composite previously pigmented appear effective in restoring the W to values similar to the original, particularly in the superficial layers of the sample.

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Review Article

Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review: Patrick Wesley Marques de Boa, Kaiza de Sousa Santos, Francisca Jennifer Duarte de Oliveira, Boniek Castillo Dutra Borges; Restor Dent Endod 2024;49(2):e14. Published online March 20, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e14

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This study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clinical trials that compared the efficacy or the in-office bleaching sensitivity between carbamide and hydrogen peroxides were included. The risk of bias was evaluated using the RoB2. The certainty of the evidence was assessed using the GRADE approach. DPI training significantly improved the mean scores of the dental undergraduates from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. The limited evidence suggests that the 37% carbamide peroxide may be similarly effective to the 35% hydrogen peroxide for bleaching teeth in-office and causes less bleaching sensitivity. However, more well-designed split-mouth clinical trials are necessary to strengthen the evidence.

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Impact of nanostructured additives in tooth bleaching agents on enhancing color change and reducing side effects: a scoping review
Patrick Wesley Marques de Boa, Kaiza de Sousa Santos, Aleph Matthews da Silva Souza, Arnóbio Antônio da Silva-Júnior, Boniek Castillo Dutra Borges
Clinical Oral Investigations.2025;[Epub] CrossRef

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Research Articles

Effect of different storage media on elemental analysis and microhardness of cervical cavity margins restored with a bioactive material: Hoda Saleh Ismail, Brian Ray Morrow, Ashraf Ibrahim Ali, Rabab Elsayed Elaraby Mehesen, Salah Hasab Mahmoud, Franklin Garcia-Godoy; Restor Dent Endod 2024;49(1):e6. Published online January 17, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e6

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Objectives

This study aimed to investigate the elemental analysis and microhardness of a bioactive material (Activa) and marginal tooth structure after storage in different media.

Materials and Methods

Fifteen teeth received cervical restorations with occlusal enamel and gingival dentin margins using the tested material bonded with a universal adhesive, 5 of them on the 4 axial surfaces and the other 10 on only the 2 proximal surfaces. The first 5 teeth were sectioned into 4 restorations each, then stored in 4 different media; deionized water, Dulbecco's phosphate buffered saline (DPBS), Tris buffer, and saliva. The storage period for deionized water was 24 hours while it was 3 months for the other media. Each part was analyzed by scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) analysis for different substrates/distances and the wt% of calcium, phosphorus, silica, and fluoride were calculated. The other 10 teeth were sectioned across the restoration, stored in either Tris buffer or saliva for 24 hours or 3 months, and were evaluated for microhardness of different substrates/areas. Data were analyzed using analysis of variance and Tukey’s post hoc test.

Results

Enamel and dentin interfaces in the DPBS group exhibited a significant increase in calcium and phosphorus wt%. Both silica and fluoride significantly increased in tooth structure up to a distance of 75 μm in the 3-month-media groups than the immediate group. Storage media did not affect the microhardness values.

Conclusions

SEM-EDS analysis suggests an ion movement between Activa and tooth structure through a universal adhesive while stored in DPBS.

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Influence of curing mode and aging on the bonding performance of universal adhesives in coronal and root dentin
Hoda Saleh Ismail, Ashraf Ibrahim Ali, Mohamed Elshirbeny Elawsya
BMC Oral Health.2024;[Epub] CrossRef

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Can different agents reduce the damage caused by bleaching gel to pulp tissue? A systematic review of basic research: Letícia Aparecida Silva Batista, Alexandre Henrique dos Reis-Prado, Hebertt Gonzaga dos Santos Chaves, Lara Cancella de Arantes, Luís Fernando Santos Alves Morgan, Carolina Bosso André, Thaís Yumi Suzuki, Francine Benetti; Restor Dent Endod 2023;48(4):e39. Published online November 6, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e39

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Objectives

This study aimed to investigate the effectiveness of different topical/systemic agents in reducing the damage caused by bleaching gel to pulp tissue or cells.

Materials and Methods

Electronic searches were performed in July 2023. In vivo and in vitro studies evaluating the effects of different topical or systemic agents on pulp inflammation or cytotoxicity after exposure to bleaching agents were included. The risk of bias was assessed.

Results

Out of 1,112 articles, 27 were included. Nine animal studies evaluated remineralizing/anti-inflammatories agents in rat molars subjected to bleaching with 35%–38% hydrogen peroxide (HP). Five of these studies demonstrated a significant reduction in inflammation caused by HP when combined with bioglass or MI Paste Plus (GC America), or following KF-desensitizing or Otosporin treatment (n = 3). However, orally administered drugs did not reduce pulp inflammation (n = 4). Cytotoxicity (n = 17) was primarily assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on human dental pulp cells and mouse dental papilla Cell-23 cells. Certain substances, including sodium ascorbate, butein, manganese chloride, and peroxidase, were found to reduce cytotoxicity, particularly when applied prior to bleaching. The risk of bias was high in animal studies and low in laboratory studies.

Conclusions

Few in vivo studies have evaluated agents to reduce the damage caused by bleaching gel to pulp tissue. Within the limitations of these studies, it was found that topical agents were effective in reducing pulp inflammation in animals and cytotoxicity. Further analyses with human pulp are required to substantiate these findings.

Trial Registration

PROSPERO Identifier: CRD42022337192

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Cytotoxicity of Bleaching Products: A Systematic Review
Mireia Montaner, José Luis Sanz, Carmen Llena, María Melo, Clara Puig-Herreros, James Ghilotti
Applied Sciences.2024; 14(9): 3680. CrossRef

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Evaluation of at-home bleaching protocol with application on different surfaces: bleaching efficacy and hydrogen peroxide permeability: Heloisa Forville, Michael Willian Favoreto, Michel Wendlinger, Roberta Micheten Dias, Christiane Philippini Ferreira Borges, Alessandra Reis, Alessandro D. Loguercio; Restor Dent Endod 2023;48(4):e33. Published online October 6, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e33

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Objectives

This study aimed to evaluate the bleaching efficacy and hydrogen peroxide permeability in the pulp chamber by the at-home bleaching gel in protocols applied on different dental surfaces.

Materials and Methods

Forty premolars were randomly into 4 groups: control group no bleaching, only application on the buccal surface (OB), only application on the lingual surface (OL) and application in buccal and lingual surfaces, simultaneously (BL). At-home bleaching gel (White Class 7.5%) was used for the procedure. The bleaching efficacy was evaluated with a digital spectrophotometer (color change in CIELAB [ΔE _ab] and CIEDE 2000 [ΔE ₀₀] systems and Whitening Index for Dentistry [ΔWI_D]). The hydrogen peroxide permeability in the pulp chamber (µg/mL) was assessed using UV-Vis spectrophotometry and data were analyzed for a 1-way analysis of variance and Tukey’s test (α = 0.05).

Results

All groups submitted to bleaching procedure showed bleaching efficacy when measured with ΔE _ab and ΔE ₀₀ (p > 0.05). Therefore, when analyzed by ΔWI_D, a higher bleaching efficacy were observed for the application on the groups OB and BL (p = 0.00003). Similar hydrogen peroxide permeability was found in the pulp chambers of the teeth undergoing different protocols (p > 0.05).

Conclusions

The application of bleaching gel exclusively on the OB is sufficient to achieve bleaching efficacy, when compared to BL. Although the OL protocol demonstrated lower bleaching efficacy based on the ΔWI_D values, it may still be of interest and relevant in certain clinical scenarios based on individual needs, requiring clinical trials to better understand its specificities.

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Effect of whitening pens on hydrogen peroxide permeability in the pulp chamber, color change and surface morphology
Laryssa Mylenna Madruga Barbosa, Gabrielle Gomes Centenaro, Deisy Cristina Ferreira Cordeiro, Maria Alice de Matos Rodrigues, Letícia Condolo, Michael Willian Favoreto, Alessandra Reis, Alessandro D. Loguercio
Journal of Dentistry.2025; 154: 105595. CrossRef
Efficacy of a buccal and lingual at‐home bleaching protocol—A randomized, split‐mouth, single‐blind controlled trial
Heloisa Forville, Laís Giacomini Bernardi, Michael Willian Favoreto, Felipe Coppla, Taynara de Souza Carneiro, Fabiana Madalozzo Coppla, Alessandro D. Loguercio, Alessandra Reis
Journal of Esthetic and Restorative Dentistry.2024; 36(9): 1301. CrossRef
REANATOMIZAÇÃO DE DENTE CONOIDE ASSOCIADA A ESTÉTICA VERMELHA: RELATO DE CASO
Ana Karolayne Sousa de Morais, Daniele Fernanda Sousa Barros, Daniel Messias Limeira, Rhana Leticia de Oliveira Faria, Roberta Furtado Carvalho, Sandna Nolêto de Araújo, Laura Barbosa Santos Di Milhomem
Revista Contemporânea.2024; 4(10): e6299. CrossRef
Effect of the reduction in the exposure time to at-home bleaching gel on color change and tooth sensitivity: A systematic review and meta-analysis
Priscila Borges Gobbo de Melo, Letícia Vasconcelos Silva Souza, Lucianne Cople Maia, Guido Artemio Marañón-Vásquez, Matheus Kury, Vanessa Cavalli
Clinical Oral Investigations.2024;[Epub] CrossRef

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Impact of combined at-home bleaching and whitening toothpaste use on the surface and color of a composite resin: Carolina Meneghin Barbosa, Renata Siqueira Scatolin, Waldemir Francisco Vieira-Junior, Marcia Hiromi Tanaka, Laura Nobre Ferraz; Restor Dent Endod 2023;48(3):e26. Published online July 26, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e26

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Objective

This in vitro study aimed to evaluate the effects of different whitening toothpastes on a composite resin during at-home bleaching with 10% carbamide peroxide.

Materials and Methods

Sixty samples (7 mm × 2 mm) were used for color and roughness analyses, while another 60 samples (3 mm × 2 mm) were utilized to assess microhardness. The factors analyzed included toothpaste, for which 5 options with varying active agents were tested (distilled water; conventional toothpaste; whitening toothpaste with abrasive agents; whitening toothpaste with abrasive and chemical agents; and whitening toothpaste with abrasive, chemical, and bleaching agents). Brushing and application of whitening gel were performed for 14 days. Surface microhardness (SMH), surface roughness (Ra), and color (∆L*, ∆a*, ∆b, ∆E*_ab, and ∆E₀₀) were analyzed. The Ra and SMH data were analyzed using mixed generalized linear models for repeated measures, while the color results were assessed using the Kruskal-Wallis and Dunn tests.

Results

Between the initial and final time points, all groups demonstrated significant increases in Ra and reductions in SMH. No significant differences were found between groups for SMH at the final time point, at which all groups differed from the distilled water group. Conventional toothpaste exhibited the lowest Ra, while whitening toothpaste with abrasive agent had the highest value. No significant differences were observed in ∆L*, ∆a*, and ∆b.

Conclusions

While toothpaste composition did not affect the color stability and microhardness of resin composite, combining toothbrushing with whitening toothpaste and at-home bleaching enhanced the change in Ra.

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At‐Home and In‐Office Bleaching Protocols on the Color Match of Restorations Made With Single‐Shade Composites
Luciana Vasconcelos Ramos, Dayana Fernandes Rocha Aparicio, André Luis Faria‐e‐Silva, Maíra do Prado, Andréa Vaz Braga Pintor, Marcela Baraúna Magno
Journal of Esthetic and Restorative Dentistry.2025;[Epub] CrossRef
Surface properties and susceptibility to staining of a resin composite after brushing with different whitening toothpastes
Aline da Silva Barros, Carolina Meneghin Barbosa, Renata Siqueira Scatolin, Waldemir Francisco Vieira Junior, Laura Nobre Ferraz
Restorative Dentistry & Endodontics.2025; 50(1): e6. CrossRef
Effect of bleaching and repolishing on whiteness change and staining susceptibility of resin-based materials
Sultan Aktuğ Karademir, Samet Atasoy, Beyza Yılmaz
BMC Oral Health.2024;[Epub] CrossRef
Influence of using different toothpaste during bleaching with violet LED light (405 nm) on the colour and roughness of dental enamel: an in vitro study
Franco Sousa Leticia, Mazzalli Redondo Victor, Ferraz Nobre Laura, Vitti Pino Rafael, Renata Siqueira Scatolin
Lasers in Medical Science.2024;[Epub] CrossRef
Effect of coffee staining and simulated oral hygiene methods on the color and translucency of a nanoceramic resin
Luiz Felipe Schneider, Bruna Mueller, Rubens Nisie Tango, Claudia Angela Maziero Volpato
Journal of Esthetic and Restorative Dentistry.2024; 36(7): 1020. CrossRef

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Review Article

Does photobiomodulation on the root surface decrease the occurrence of root resorption in reimplanted teeth? A systematic review of animal studies: Theodoro Weissheimer, Karolina Frick Bischoff, Carolina Horn Troian Michel, Bruna Barcelos Só, Manoela Domingues Martins, Matheus Albino Souza, Ricardo Abreu da Rosa, Marcus Vinícius Reis Só; Restor Dent Endod 2023;48(3):e24. Published online June 12, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e24

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This review aimed to answer the following question “Does photobiomodulation treatment of the root surface decrease the occurrence of root resorption in reimplanted teeth?” Electronic searches were performed in the MEDLINE/PubMed, Cochrane Library, Scopus, Web of Science, Embase, and Grey Literature Report databases. Risk of bias was evaluated using SYRCLE Risk of Bias tool. The Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) tool was used to assess the certainty of evidence. In total, 6 studies were included. Five studies reported a reduced occurrence of root resorption in teeth that received photobiomodulation treatment of the root surface prior to replantation. Only 1 study reported contradictory results. The photobiomodulation parameters varied widely among studies. GRADE assessment showed a low certainty of evidence. It can be inferred that photobiomodulation treatment of the root surface prior to replantation of teeth can reduce the occurrence of root resorption. Nonetheless, further clinical studies are needed.

Trial Registration

PROSPERO Identifier: CRD42022349891

Citations

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Feasibility and Outcomes of Cell-based Regenerative Endodontic Therapy in Postautogenous Transplantation of a Mature Tooth: A Case Report
Noriaki Yoshihashi
Journal of Endodontics.2025; 51(1): 85. CrossRef
Photobiomodulation Literature Watch September 2023
James D. Carroll
Photobiomodulation, Photomedicine, and Laser Surgery.2024; 42(7): 498. CrossRef

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Research Articles

Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis: Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura; Restor Dent Endod 2023;48(2):e21. Published online May 5, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e21

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Objectives

This study evaluated the effects of Biodentine (BD), Bio-C Repair (BCR), and mineral trioxide aggregate (MTA) plug on the fracture resistance of simulated immature teeth with replacement root resorption (RRR) and in vitro-induced osteoclastogenesis.

Materials and Methods

Sixty bovine incisors simulating immature teeth and RRR were divided into 5 groups: BD and BCR groups, with samples completely filled with the respective materials; MTA group, which utilized a 3-mm apical MTA plug; RRR group, which received no root canal filling; and normal periodontal ligament (PL) group, which had no RRR and no root canal filling. All the teeth underwent cycling loading, and compression strength testing was performed using a universal testing machine. RAW 264.7 macrophages were treated with 1:16 extracts of BD, BCR, and MTA containing receptor activator of nuclear factor-kappa B ligand (RANKL) for 5 days. RANKL-induced osteoclast differentiation was assessed by staining with tartrate-resistant acid phosphatase. The fracture load and osteoclast number were analyzed using 1-way ANOVA and Tukey’s test (α = 0.05).

Results

No significant difference in fracture resistance was observed among the groups (p > 0.05). All materials similarly inhibited osteoclastogenesis (p > 0.05), except for BCR, which led to a lower percentage of osteoclasts than did MTA (p < 0.0001).

Conclusions

The treatment options for non-vital immature teeth with RRR did not strengthen the teeth and promoted a similar resistance to fractures in all cases. BD, MTA, and BCR showed inhibitory effects on osteoclast differentiation, with BCR yielding improved results compared to the other materials.

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Comparative Analysis of Gene Expression in Periodontal Ligament Stem Cells Exposed to Biodentine and Bio-C Repair: Implications for Cementogenesis—An In Vitro Study
Mahmoud M. Bakr, Mahmoud Al Ankily, Mohammed Meer, Mohamed Shamel
Oral.2025; 5(1): 19. CrossRef
Evaluation of Different Techniques and Materials for Filling in 3-dimensional Printed Teeth Replicas with Perforating Internal Resorption by Means of Micro–Computed Tomography
Angelo J.S. Torres-Carrillo, Helena C. Assis, Rodrigo E. Salazar-Gamarra, Leonardo Moreira Teodosio, Alice C. Silva-Sousa, Jardel F. Mazzi-Chaves, Priscila B. Ferreira-Soares, Manoel D. Sousa-Neto, Fabiane C. Lopes-Olhê
Journal of Endodontics.2024; 50(2): 205. CrossRef
In vitro comparison of fracture strength of maxillary incisors with the simulated external root resorption cavities repaired with BioMTA or Biodentine
Tufan Ozasir, Birgul Ozasir, Nagihan Aribal, Derin Bugu Yuzer, Baris Kandemir, Kamran Gulsahi
Journal of Dental Sciences.2024;[Epub] CrossRef

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Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial: Luísa Valente Gotardo Lara Alves, Lisiane Martins Fracasso, Thiago Vinicius Cortez, Aline Evangelista Souza-Gabriel, Silmara Aparecida Milori Corona; Restor Dent Endod 2023;48(2):e13. Published online March 20, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e13

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Natural extracts have been investigated as a biomimetic strategy to mechanically strengthen the collagen network and control the biodegradation of extracellular matrix. This study evaluated the effect of epigallocatechin-3-gallate (EGCG) on abfraction lesions prior to the composite resin.
Materials and Methods
The sample consisted of 30 patients (aged between 28 and 60 years) with abfraction lesions located in 2 homologous premolars. The teeth were randomly assigned according to dentin treatment: 0.02% EGCG solution or distilled water (control). After enamel acid etching, the solutions were applied immediately for 1 minute. The teeth were restored with Universal Adhesive (3M) and Filtek Z350 XT (3M). Analyzes were done by 2 independent examiners using modified USPHS (retention, secondary caries, marginal adaptation, and postoperative sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at baseline (7 days) and final (18 months). The data analysis used Friedman and Wilcoxon signed-rank tests (α = 0.05).
Results
At baseline, all restorations were evaluated as alpha for all criteria. After 18 months, restorations were evaluated as alpha for secondary caries, color, and marginal pigmentation. There was significant difference between baseline and 18 months (p = 0.009) for marginal adaptation and postoperative sensitivity (p = 0.029), but no significant difference were verified between treatments (p = 0.433). The EGCG group had a restoration retention rate of 93.3%, while the control group had 96.7%.
Conclusions
The application of EGCG solution on abfraction lesions did not significantly influence the survival of the restorations based on clinical and photographic criteria.

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Resin infiltrant protects deproteinized dentin against erosive and abrasive wear: Ana Theresa Queiroz de Albuquerque, Bruna Oliveira Bezerra, Isabelly de Carvalho Leal, Maria Denise Rodrigues de Moraes, Mary Anne S. Melo, Vanara Florêncio Passos; Restor Dent Endod 2022;47(3):e29. Published online July 1, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e29

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Objectives

This study aimed to investigate the anti-erosive/abrasive effect of resin infiltration of previous deproteinized dentin.

Materials and Methods

Dentin slabs were randomly assigned to 3 groups (n = 15): Control (no deproteinization; no resin infiltrant applied), RI (no deproteinization; resin infiltrant applied), and DRI (deproteinization; resin infiltrant applied). After undergoing the assigned treatment, all slabs were subjected to an in vitro cycling model for 5 days. The specimens were immersed in citric acid (0.05 M, pH = 3.75; 60 seconds; 3 times/day) and brushed (150 strokes). Between the challenges, the specimens were exposed to a remineralizing solution (60 minutes). The morphological alterations were analyzed by mechanical profilometry (µm) and scanning electron microscopy (SEM). Data were submitted to one-way analysis of variance (ANOVA) and Tukey tests (p < 0.05).

Results

Control and RI groups presented mineral wear and did not significantly differ from each other (p = 0.063). DRI maintained a protective layer preserving the dentin (p < 0.001). After erosive/abrasive cycles, it was observed that in group RI, only 25% of the slabs partially evidenced the presence of the infiltrating, while, in the DRI group, 80% of the slabs presented the treated surface entirely covered by a resin-component layer protecting the dentin surface as observed in SEM images.

Conclusions

The removal of the organic content allows the resin infiltrant to efficiently protect the dentin surface against erosive/abrasive lesions.

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Acidic/abrasive challenges on simulated non-carious cervical lesions development and morphology
Giovanna C. Denucci, Ian Towle, Cecilia P. Turssi, George J. Eckert, Anderson T. Hara
Archives of Oral Biology.2025; 169: 106120. CrossRef
Physio‐Mechanic and Microscopic Analyses of Bioactive Glass‐Based Resin Infiltrants
Syed Zubairuddin Ahmed, Abdul Samad Khan, Wejdan Waleed Nasser, Methayel Abdulrahman Alrushaid, Zahrah Mohammed Alfaraj, Moayad Mohammed Aljeshi, Asma Tufail Shah, Budi Aslinie Md Sabri, Sultan Akhtar, Mohamed Ibrahim Abu Hassan
Microscopy Research and Technique.2025; 88(2): 595. CrossRef

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Case Report

Persistent pain after successful endodontic treatment in a patient with Wegener’s granulomatosis: a case report: Ricardo Machado, Jorge Aleixo Pereira, Filipe Colombo Vitali, Michele Bolan, Elena Riet Correa Rivero; Restor Dent Endod 2022;47(3):e26. Published online June 9, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e26

Abstract PDF PubReader ePub: Wegener’s granulomatosis (WG) is a condition with immune-mediated pathogenesis that can present oral manifestations. This report describes the case of a patient diagnosed with WG 14 years previously, who was affected by persistent pain of non-odontogenic origin after successful endodontic treatment. A 39-year-old woman with WG was diagnosed with pulp necrosis and apical periodontitis of teeth #31, #32, and #41, after evaluation through a clinical examination and cone-beam computed tomography (CBCT). At the first appointment, these teeth were subjected to conventional endodontic treatment. At 6- and 12-month follow-up visits, the patient complained of persistent pain associated with the endodontically treated teeth (mainly in tooth #31), despite complete remission of the periapical lesions shown by radiographic and CBCT exams proving the effectiveness of the endodontic treatments, thus indicating a probable diagnostic of persistent pain of non-odontogenic nature. After the surgical procedure was performed to curette the lesion and section 3 mm of the apical third of tooth #31, the histopathological analysis suggested that the painful condition was likely associated with the patient's systemic condition. Based on clinical, radiographic, and histopathological findings, this unusual case report suggests that WG may be related to non-odontogenic persistent pain after successful endodontic treatments.

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Research Articles

In-office dental bleaching with violet light emitting diode: bleaching efficacy and pulpal temperature rise: Brunna Katyuscia de Almeida Guanaes, Talyta Neves Duarte, Gisele Maria Correr, Marina da Rosa Kaizer, Carla Castiglia Gonzaga; Restor Dent Endod 2022;47(1):e7. Published online February 3, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e7

Abstract PDF PubReader ePub

Objectives

This study evaluated the bleaching efficacy of different in-office protocols associated with violet light emitting diode (V-LED), and measured the pulpal temperature rise caused by V-LED with or without gel application.

Materials and Methods

Bovine incisors were distributed in 4 groups (n = 10): VL – V-LED; HP – 35% hydrogen peroxide (control); HYB – hybrid protocol, V-LED applied without gel for 10 irradiation cycles followed by V-LED applied with gel for another 10 irradiation cycles; and HPVL – gel and V-LED applied for 20 irradiation cycles. Three bleaching sessions were performed with 7-day intervals. Bleaching efficacy was evaluated with $ΔEab*$ , ΔE₀₀ and ΔWI_D. Data were recorded at baseline, 7, 14, 21 and 70 days. For pulpal temperature rise, thermocouples were placed inside the pulp chamber of human incisors. To determine intrapulpal temperature, the teeth were irradiated with V-LED with or without application of bleaching gel. Color difference data were analyzed by 2-way repeated measures ANOVA and Tukey’s test. Pulpal temperature was analyzed by t-test (α = 5%).

Results

VL exhibited lower color ( $ΔEab*$ and ΔE₀₀) and whiteness changes (ΔWI_D) than the other groups. HPVL presented higher color change values than HYB. HYB and HPVL showed not different ΔWI_D values; and HP showed the highest whiteness changes at all times. There were significant differences comparing ΔT with gel (8.9°C) and without gel application (7.2°C).

Conclusions

HPLV was more efficient than HYB. The 2 protocols with VL showed similar results to control. Gel application combined with VL promoted higher pulpal temperature than to the no gel group.

Citations

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Effect of antioxidant on tooth sensitivity after bleaching
Mohamed Nabil, Mostafa Mohamed Hasan, Eman Abd Elghany Shebl
Journal of Esthetic and Restorative Dentistry.2024; 36(3): 429. CrossRef
In-office Bleaching Activated With Violet LED: Effect on Pulpal and Tooth Temperature and Pulp Viability
NR Carlos, RT Basting, KR Kantovitz, ES Bronze-Uhle, PN Lisboa Filho, V Cavalli, RT Basting
Operative Dentistry.2024; 49(3): 262. CrossRef
Low and high hydrogen peroxide concentrations of in-office dental bleaching associated with violet light: an in vitro study
Isabela Souza Vardasca, Michael Willian Favoreto, Mylena de Araujo Regis, Taynara de Souza Carneiro, Emanuel Adriano Hul, Christiane Philippini Ferreira Borges, Alessandra Reis, Alessandro D. Loguercio, Carlos Francci
Clinical Oral Investigations.2024;[Epub] CrossRef
Bleaching efficacy of in-office bleaching with violet light using low-concentration hydrogen peroxide nanoparticulate photocatalyst gel: A randomized controlled trial
Gustavo Garcia Castro, Palena Araújo Pinto, Michael Willian Favoreto, Alessandra Reis, Maria Viviana-Mora, Rita de Cássia Mendonça de Miranda, Andres Felipe Milan Cardenas, Alessandro D. Loguercio, Rudys Rodolfo de Jesus Tavarez
Photodiagnosis and Photodynamic Therapy.2024; 50: 104410. CrossRef
Continuous vs fractionated violet LED light protocols for dental bleaching: Evaluations of color change and temperature of the dental pulp and buccal surface
Mayanna Pacheco Trindade Najar, Luciana Hilel Rangel Barbosa, Natália Russo Carlos, Fabiana Mantovani Gomes França, Cecilia Pedroso Turssi, Waldemir Francisco Vieira-Junior, Roberta Tarkany Basting
Photodiagnosis and Photodynamic Therapy.2023; 42: 103631. CrossRef
Improved esthetic efficacy and reduced cytotoxicity are achieved with a violet LED irradiation of manganese oxide-enriched bleaching gels
Marlon Ferreira Dias, Beatriz Voss Martins, Rafael Antonio de Oliveira Ribeiro, Josimeri Hebling, Carlos Alberto de Souza Costa
Lasers in Medical Science.2022;[Epub] CrossRef

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Effect of hydrogel-based antibiotic intracanal medicaments on crown discoloration: Rayan B. Yaghmoor, Jeffrey A. Platt, Kenneth J. Spolnik, Tien Min Gabriel Chu, Ghaeth H. Yassen; Restor Dent Endod 2021;46(4):e52. Published online October 5, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e52

Abstract PDF PubReader ePub

Objectives

This study evaluated the effects of low and moderate concentrations of triple antibiotic paste (TAP) and double antibiotic paste (DAP) loaded into a hydrogel system on crown discoloration and explored whether application of an adhesive bonding agent prevented crown discoloration.

Materials and Methods

Intact human molars (n = 160) were horizontally sectioned 1 mm apical to the cementoenamel junction. The crowns were randomized into 8 experimental groups (calcium hydroxide, Ca[OH]₂; 1, 10, and 1,000 mg/mL TAP and DAP; and no medicament. The pulp chambers in half of the samples were coated with an adhesive bonding agent before receiving the intracanal medicament. Color changes (ΔE) were detected by spectrophotometry after 1 day, 1 week, and 4 weeks, and after 5,000 thermal cycles, with ΔE = 3.7 as a perceptible threshold. The 1-sample t-test was used to determine the significance of color changes relative to 3.7. Analysis of variance was used to evaluate the effects of treatment, adhesive, and time on color change, and the level of significance was p < 0.05.

Results

Ca(OH)₂ and 1 and 10 mg/mL DAP did not cause clinically perceivable tooth discoloration. Adhesive agent use significantly decreased tooth discoloration in the 1,000 mg/mL TAP group up to 4 weeks. However, adhesive use did not significantly improve coronal discoloration after thermocycling when 1,000 mg/mL TAP was used.

Conclusions

Ca(OH)₂ and 1 and 10 mg/mL DAP showed no clinical discoloration. Using an adhesive significantly improved coronal discoloration up to 4 weeks with 1,000 mg/mL TAP.

Citations

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Root Canal Dentin Microhardness after Contact with Antibiotic Medications: An In Vitro Study
Amanda Palmeira Arruda Nogueira, Renata Grazziotin-Soares, Adriana Marques Mesquita Leal, Sérgio Alves Guida Freitas Júnior, Bruna Laís Lins Gonçalves, José Bauer, Meire Coelho Ferreira, Ceci Nunes Carvalho
Dentistry Journal.2024; 12(7): 201. CrossRef
Potential Crown Discoloration Induced by the Combination of Various Intracanal Medicaments and Scaffolds Applied in Regenerative Endodontic Therapy
NB Altun, A Turkyilmaz
Nigerian Journal of Clinical Practice.2024; 27(7): 897. CrossRef

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Laboratory model to evaluate efficacy of an experimental titanium oxide nanofibers bleaching agent: Clayton Tran, Ellin Choi, Brittany Watu, Udochukwu Oyoyo, Christopher Perry, So Ran Kwon; Restor Dent Endod 2021;46(4):e47. Published online September 2, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e47

Abstract PDF PubReader ePub

Objectives

This study aimed to use a laboratory model to evaluate the efficacy of an experimental bleaching agent.

Materials and Methods

The model used human extracted molars that were treated and measured for bleaching efficacy. Teeth (n = 50) were distributed into 5 groups: Negative control (NC): immersion in water for 8 hours; Nanofibers (NFs): Experimental titanium dioxide nanofibers with stirring and light activation for 8 hours; Whitestrips (WS): Crest 3D White Glamorous White Whitestrips, 2 applications daily for 30 minutes, 14 days; 1% hydrogen peroxide (HP) standard: 1% hydrogen peroxide for 8 hours; and 30% HP standard: 30% hydrogen peroxide for 8 hours. Instrumental measurements were performed using a spectrophotometer. Results were recorded at baseline, 1-day post-bleaching, and 1-week post-bleaching. Kruskal-Wallis procedure was used to determine differences in color change. Pearson correlation was used to evaluate the relationship between visual and instrumental measurements. Tests of hypotheses were 2-sided with alpha = 0.05.

Results

There was no significant difference in color parameters (L1, a1, b1, and shade guide units [SGU]) at baseline (p > 0.05). There was a significant difference among the groups for overall color change (ΔE*ab) and change in shade guide units (ΔSGU) at 1-day and 1-week post-bleaching (p < 0.05). The higher the HP concentration, the higher the color change as expressed in ΔSGU and ΔE*ab. The negative control exceeded the perceptibility threshold of ΔE* = 1.2 regardless of time point. NFs showed a decrease in chroma, but were not statistically different compared to the negative control.

Conclusions

The laboratory model was successful in screening an experimental bleaching agent.

Citations

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Evaluating the Efficacy of Titanium Dioxide Nanoparticles in Combination with Commonly Used Bleaching Agents: An In Vitro Study
Rajasekhar Vemareddy, Sudhakar Naidu, Bala Raju Korrai, Shanmukha Nagadevara, Someshwar Battu, Jyotsnanjali Thati, Sivaji Kavuri
World Journal of Dentistry.2024; 15(5): 377. CrossRef

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Microleakage and characteristics of resin-tooth tissues interface of a self-etch and an etch-and-rinse adhesive systems: Xuan Vinh Tran, Khanh Quang Tran; Restor Dent Endod 2021;46(2):e30. Published online May 18, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e30

Abstract PDF PubReader ePub

Objectives

This study was conducted to compare the microleakage and characteristics of the resin-tooth tissue interface between self-etch and etch-and-rinse adhesive systems after 48 hours and 3 months.

Materials and Methods

40 extracted premolar teeth were randomly divided into 2 groups: 1-step self-etch adhesive system – Optibond™ All-In-One, and 2-step etch-and-rinse adhesive system - Adper™ Single Bond 2. Both groups were subjected to 500 thermocycles (5°C–55°C) before scanning electron microscope (SEM) analysis or microleakage trial at 48-hour and 3-month time periods.

Results

SEM images showed the hybrid layer thickness, diameter, and length of resin tags of the self-etch adhesive (0.42 ± 0.14 µm; 1.49 ± 0.45 µm; 16.35 ± 14.26 µm) were smaller than those of the etch-and-rinse adhesive (4.39 ± 1.52 µm; 3.49 ± 1 µm; 52.81 ± 35.81 µm). In dentin, the microleakage scores of the 2 adhesives were not different in both time periods (48 hours/3 months). However, the microleakage score of etch-and-rinse adhesive increased significantly after 3 months (0.8 ± 0.63 and 1.9 ± 0.88, p < 0.05).

Conclusions

The self-etch adhesive exhibited better long-term sealing ability in dentin when compared to that of the etch-and-rinse adhesive. The greater hybrid layer thickness and dimensions of resin tags did not guarantee reliable, long-lasting sealing in the bonding area.

Citations

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Efficacy of different adhesive systems in bonding direct resin composite restorations: a systematic review and meta-analysis
Ravinder S. Saini, Rajesh Vyas, Sunil Kumar Vaddamanu, Syed Altafuddin Quadri, Seyed Ali Mosaddad, Artak Heboyan
Evidence-Based Dentistry.2025;[Epub] CrossRef
Resin tags formation by modified Renewal MI formulations in a carious dentine model
Nabih Alkhouri, Wendy Xia, Paul Ashley, Anne Young
Frontiers in Oral Health.2024;[Epub] CrossRef
Effect of propolis added to single‐bottle adhesives on water permeation through the hybrid layer
Lucineide Silva da Rocha, Daniela Ferreira de Oliveira, Cinthya Luna Veloso de Lima, Ticiano Gomes do Nascimento, Johnnatan Duarte de Freitas, Jeniffer Mclaine Duarte de Freitas, Isabel Cristina Celerino de Moraes Porto
European Journal of Oral Sciences.2024;[Epub] CrossRef
Exploration and preliminary clinical investigation of an adhesive approach for primary tooth restoration
Xiangqin Xu, Jiansheng Zhu, May Lei Mei, Huaying Wu, Kaipeng Xie, Shoulin Wang, Yaming Chen
The Journal of Biomedical Research.2023; 37(2): 138. CrossRef
Adhesion to enamel and dentine: an update
Rana Alkattan
Primary Dental Journal.2023; 12(3): 33. CrossRef
Effects of carbodiimide combined with ethanol–wet bonding pretreatment on dentin bonding properties: an in vitro study
Xiaoxiao You, Long Chen, Jie Xu, Sihui Li, Zhenghao Zhang, Ling Guo
PeerJ.2022; 10: e14238. CrossRef
The effects of amalgam contamination and different surface modifications on microleakage of dentin bonded to bulk fill composite when using different adhesive protocols
Nojoud Alshehri, Abdullah Aljamhan, Mohammed Bin-Shuwaish
BMC Oral Health.2022;[Epub] CrossRef
Development of low-shrinkage dental adhesives via blending with spiroorthocarbonate expanding monomer and unsaturated epoxy resin monomer
Zonghua Wang, Xiaoran Zhang, Shuo Yao, Jiaxin Zhao, Chuanjian Zhou, Junling Wu
Journal of the Mechanical Behavior of Biomedical Materials.2022; 133: 105308. CrossRef
Influence of silver nanoparticles on the resin-dentin bond strength and antibacterial activity of a self-etch adhesive system
Jia Wang, Wei Jiang, Jingping Liang, Shujun Ran
The Journal of Prosthetic Dentistry.2022; 128(6): 1363.e1. CrossRef

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Retrospective study of fracture survival in endodontically treated molars: the effect of single-unit crowns versus direct-resin composite restorations: Kanet Chotvorrarak, Warattama Suksaphar, Danuchit Banomyong; Restor Dent Endod 2021;46(2):e29. Published online May 6, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e29

Abstract PDF PubReader ePub

Objectives

This study was conducted to compare the post-fracture survival rate of endodontically treated molar endodontically treated teeth (molar ETT) restored with resin composites or crowns and to identify potential risk factors, using a retrospective cohort design.

Materials and Methods

Dental records of molar ETT with crowns or composite restorations (recall period, 2015–2019) were collected based on inclusion and exclusion criteria. The incidence of unrestorable fractures was identified, and molar ETT were classified according to survival. Information on potential risk factors was collected. Survival rates and potential risk factors were analyzed using the Kaplan-Meier log-rank test and Cox regression model.

Results

The overall survival rate of molar ETT was 87% (mean recall period, 31.73 ± 17.56 months). The survival rates of molar ETT restored with composites and crowns were 81.6% and 92.7%, reflecting a significant difference (p < 0.05). However, ETT restored with composites showed a 100% survival rate if only 1 surface was lost, which was comparable to the survival rate of ETT with crowns. The survival rates of ETT with composites and crowns were significantly different (97.6% vs. 83.7%) in the short-term (12–24 months), but not in the long-term (> 24 months) (87.8% vs. 79.5%).

Conclusions

The survival rate from fracture was higher for molar ETT restored with crowns was higher than for ETT restored with composites, especially in the first 2 years after restoration. Molar ETT with limited tooth structure loss only on the occlusal surface could be successfully restored with composite restorations.

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Risk factors for the appearance of cracks and fractures of teeth according to a survey of dentists
Emilia A. Olesova, Alexander A. Ilyin, Sergey D. Arutyunov, Elena V. Glazkova, Arsen A. Popov, Svetlana P. Iarilkina
Russian Journal of Dentistry.2024; 28(6): 562. CrossRef
Performance of Bonded Lithium Disilicate Partial-coverage Crowns in the Restoration of Endodontically Treated Posterior Teeth: An Up to Seven-Year Retrospective Study
Q Jiang, Z Wang, S Zhang, X Liu, B Fu
Operative Dentistry.2024; 49(4): 365. CrossRef
In Vitro Bond Strength of Dentin Treated with Sodium Hypochlorite: Effects of Antioxidant Solutions
Guillermo Grazioli, Elisa de León Cáceres, Romina Tessore, Rafael Lund, Ana Monjarás-Ávila, Monika Lukomska-Szymanska, Louis Hardan, Rim Bourgi, Carlos Cuevas-Suárez
Antioxidants.2024; 13(9): 1116. CrossRef
Stress Analysis on Mesiolingual Cavity of Endodontically Treated Molar Restored Using Bidirectional Fiber-Reinforced Composite (Wallpapering Technique)
Harnia Neri, Dudi Aripin, Anna Muryani, Hendra Dharsono, Yolanda Yolanda, Andi Mahyuddin
Clinical, Cosmetic and Investigational Dentistry.2024; Volume 16: 75. CrossRef
Effect of Luting Cement Film Thickness on the Pull-Out Bond Strength of Endodontic Post Systems
Khalil Aleisa, Syed Rashid Habib, Abdul Sadekh Ansari, Ragad Altayyar, Shahad Alharbi, Sultan Ali S. Alanazi, Khalid Tawfik Alduaiji
Polymers.2021; 13(18): 3082. CrossRef

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Case Report

Endodontic approach in a replanted tooth with an immature root apex and chronic apical periodontitis: a case report: Graziela Garrido Mori, Bruna Souza Andrade, Marina Bardelli Araujo; Restor Dent Endod 2020;45(3):e29. Published online May 21, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e29

Abstract PDF PubReader ePub

This study describes the clinical steps taken in the treatment of a patient who had an avulsed right upper central incisor that presented with incomplete root development and chronic apical periodontitis. A 7-year-old boy was referred from a private dentist to a dental office specializing in endodontics. The tooth had remained in a dry environment for 20 minutes, and tooth replantation was performed at an emergency appointment. After clinical and radiographic examinations, root canal decontamination was performed, followed by several changes in intracanal calcium hydroxide medication. Blood clot formation was attempted, but bleeding within the root canal was insufficient; therefore, we opted for an intracanal medication change to stimulate mineralized tissue formation in the apical region. Root obturation was performed 45 days after the last change of intracanal medication, and clinical, radiographic, and tomographic follow-up examinations were performed at 3, 6, 18, and 40 months after the endodontic intervention. The increase in thickness and length of the root structure and the absence of root resorption were verified through follow-up examinations. Therefore, it was concluded that the procedures used were successful for tooth replantation.

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The Impact of the Preferred Reporting Items for Case Reports in Endodontics (PRICE) 2020 Guidelines on the Reporting of Endodontic Case Reports
Sofian Youssef, Phillip Tomson, Amir Reza Akbari, Natalie Archer, Fayjel Shah, Jasmeet Heran, Sunmeet Kandhari, Sandeep Pai, Shivakar Mehrotra, Joanna M Batt
Cureus.2023;[Epub] CrossRef

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Research Articles

Influence of pain-relieving therapies on inflammation and the expression of proinflammatory neuropeptides after dental bleaching treatment: Livia Maria Alves Valentim da Silva, Luciano Tavares Angelo Cintra, Marjorie de Oliveira Gallinari, Francine Benetti, Vanessa Rahal, Edilson Ervolino, Sibele de Alcântara, André Luiz Fraga Briso; Restor Dent Endod 2020;45(2):e20. Published online February 28, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e20

Abstract PDF PubReader ePub

Objectives

To minimize the tooth sensitivity caused by in-office bleaching, many dentists use non-steroidal anti-inflammatory drugs and topical desensitizing gels containing potassium nitrate and sodium fluoride. This study aimed to evaluate the influence of these substances on inflammation and the expression of substance P and calcitonin gene-related peptide in pulp nerve fibers.

Materials and Methods

Seventy-two rats were divided into 6 groups as follows: GI, control; GII, only dental bleaching; GIII, only ibuprofen; GIV, ibuprofen administered 30 minutes before and after the bleaching treatment and every 12 hours until the analysis; GV, only topical application of a desensitizing agent; and GVI, topical application of a desensitizing agent before dental bleaching. Placebo gel was applied to the upper left jaw and the bleaching agent was applied to the upper right jaw in all groups. Subsequently, the groups were divided into 3 subgroups based on the time of analysis: 0, 24, and 48 hours after bleaching (n = 8). The rats were euthanized and the maxillae were processed and evaluated by histopathological and immunohistochemical analyses. The data were analyzed using the Kruskal-Wallis test, followed by the Dunn test (p < 0.05).

Results

In the bleaching groups, the inflammatory process and expression of neuropeptides decreased over time. The animals in which a desensitizing agent was applied showed better results within 24 hours.

Conclusions

The use of a desensitizing agent had positive effects on inflammation and pain-related neuropeptide expression, minimizing the painful effects of dental bleaching treatment.

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Effectiveness of Analgesics in Dental Whitening Pain Management: A Systematic Review and Meta-Analysis
Gabriella Alves Julião Costa, Caio Ferreira Freire Caetano, Ravy Jucá Farias, Diana Araújo Cunha, Dayrine Silveira de Paula, Edson Luiz Cetira Filho, Paulo Goberlânio de Barros Silva
Expert Opinion on Pharmacotherapy.2025; 26(5): 639. CrossRef
Influence of dental bleaching on the pulp tissue: A systematic review of in vivo studies
Mariana Viana Donato, Alexandre Henrique dos Reis‐Prado, Lucas Guimarães Abreu, Lara Cancella de Arantes, Juliana Goto, Hebertt Gonzaga dos Santos Chaves, Luciano Tavares Angelo Cintra, André Luiz Fraga Briso, Isabella Faria da Cunha Peixoto, Francine Ben
International Endodontic Journal.2024; 57(6): 630. CrossRef
Role of induced nitric oxide synthases in orofacial nociception/discomfort after dental tooth bleaching with hydrogen peroxide
Marcílio Rodrigues Pinto, Kirlya Isabel da Silva Medeiros, Letícia Menezes Maia, Antonio Alexandre Coelho, Ana Paula Negreiros Nunes Alves, Caio Ferreira Freire Caetano, Karine Cestaro Mesquita, Paulo Goberlânio de Barros Silva, Fabricio Bitu Sousa
Archives of Oral Biology.2024; 161: 105937. CrossRef
Can different agents reduce the damage caused by bleaching gel to pulp tissue? A systematic review of basic research
Letícia Aparecida Silva Batista, Alexandre Henrique dos Reis-Prado, Hebertt Gonzaga dos Santos Chaves, Lara Cancella de Arantes, Luís Fernando Santos Alves Morgan, Carolina Bosso André, Thaís Yumi Suzuki, Francine Benetti
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
The Effects of Different Drugs with Anti-Inflamatory Potential in Prevention of Pulp Damage During the Teeth Bleaching
Miona Glisic, Andjela Milojevic, Milica Milinkovic, Marina Rankovic
Experimental and Applied Biomedical Research (EABR).2023;[Epub] CrossRef
Bleaching gel volume influences hydrogen peroxide diffusion, inflammation, and the presence of nitric oxide in the pulp tissue: in vitro and in vivo model
Sibele de ALCÂNTARA, Francine BENETTI, Lívia Maria Alves Valentim da SILVA, Nathália Evelyn da Silva MACHADO, Isabela Joane Prado SILVA, Lara Maria Bueno ESTEVES, Edilson ERVOLINO, Luciano Tavares Angelo CINTRA, André Luiz Fraga BRISO
Journal of Applied Oral Science.2023;[Epub] CrossRef
Design of a thermosensitive ibuprofen-loaded nanogel as smart material applied as anti-inflammatory in tooth bleaching: An in vivo study
Samara K.S.C.F. Moura, Milena L.V. dos Santos, Lucas A. do Nascimento, Mariana F.A. da Silva, Glória M. de França, Lucas M. da Costa, Aldo C. Medeiros, Raimundo F. Araújo-Júnior, Aurigena A. de Araújo, Cláudia N. Oliveira, André L. Dorini, Rejane A. de Ca
Journal of Drug Delivery Science and Technology.2022; 68: 103123. CrossRef
Topical application of Otosporin® before in-office bleaching: a split mouth, triple-blind, multicenter randomized clinical trial
Michael Willian Favoreto, Laína Vochikovski, Renata Maria Oleniki Terra, Veridiana Silva Campos, Mariana Evangelista Santos, Sônia Saeger Meireles, Alessandra Reis, Alessandro D. Loguercio
Clinical Oral Investigations.2022; 26(3): 2555. CrossRef
A novel tooth bleaching gel based on peroxymonosulfate/polyphosphates advanced oxidation process: Effective whitening avoiding pulp damage and sensitivity
Su Yang, Baiyan Sui, Xin Liu, Jiao Sun, Jun Wang
Chemical Engineering Journal.2022; 429: 132525. CrossRef
Effectiveness of Violet LED alone or in association with bleaching gel during dental photobleaching: A Systematic Review
Bianca Rossi, Susana Morimoto, Tamara Kerber Tedesco, Sandra Ribeiro Cunha, Anna Carolina Ratto Tempestini Horliana, Karen Müller Ramalho
Photodiagnosis and Photodynamic Therapy.2022; 38: 102813. CrossRef

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Effect of dental bleaching on the microhardness and surface roughness of sealed composite resins: Renan Aparecido Fernandes, Henrico Badaoui Strazzi-Sahyon, Thaís Yumi Umeda Suzuki, André Luiz Fraga Briso, Paulo Henrique dos Santos; Restor Dent Endod 2020;45(1):e12. Published online January 10, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e12

Abstract PDF PubReader ePub

Objectives

The aim of this in vitro study was to evaluate the microhardness and surface roughness of composite resins before and after tooth bleaching procedures.

Materials and Methods

Sixty specimens were prepared of each composite resin (Filtek Supreme XT and Opallis), and BisCover LV surface sealant was applied to half of the specimens. Thirty enamel samples were obtained from the buccal and lingual surfaces of human molars for use as the control group. The surface roughness and microhardness were measured before and after bleaching procedures with 35% hydrogen peroxide or 16% carbamide (n = 10). Data were analyzed using 1-way analysis of variance and the Fisher test (α = 0.05).

Results

Neither hydrogen peroxide nor carbamide peroxide treatment significantly altered the hardness of the composite resins, regardless of surface sealant application; however, both treatments significantly decreased the hardness of the tooth samples (p < 0.05). The bleaching did not cause any change in surface roughness, with the exception of the unsealed Opallis composite resin and dental enamel, both of which displayed an increase in surface roughness after bleaching with carbamide peroxide (p < 0.05).

Conclusions

The microhardness and surface roughness of enamel and Opallis composite resin were influenced by bleaching procedures.

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Effect of Bleaching on Surface Roughness and Color Parameters of Coffee-Stained Nanohybrid Dental Composites with Different Viscosities
Hetaf S. Redwan, Mohamed A. Hussein, Mohamed M. Abdul-Monem
European Journal of General Dentistry.2025; 14(01): 027. CrossRef
Effect of Staining and External Bleaching on the Color Stability and Surface Roughness of Universal-Shade Resin-Based Composite
AlHanouf AlHabdan, Amal Alsuhaibani, Lama Alomran, Lulwah Almutib
Clinical, Cosmetic and Investigational Dentistry.2025; Volume 17: 1. CrossRef
Comparative Analysis Between Strip and Gels Indicated for at Home Bleaching: Analysis of Color Alteration, Roughness and Microhardness of Dental Enamel
K. M. S. Aidar, L. T. A. Cintra, M. C. B. Ferreira, T. C. Fagundes, L. M. B. Esteves, J. Goto, A. Catelan, A. L. F. Briso
Journal of Esthetic and Restorative Dentistry.2025;[Epub] CrossRef
Surface properties and susceptibility to staining of a resin composite after brushing with different whitening toothpastes
Aline da Silva Barros, Carolina Meneghin Barbosa, Renata Siqueira Scatolin, Waldemir Francisco Vieira Junior, Laura Nobre Ferraz
Restorative Dentistry & Endodontics.2025; 50(1): e6. CrossRef
Comparison of Microhardness and Surface Roughness of New Nanofiber Filled Flowable Composite
Rumeysa Hatice ENGINLER OZLEN, Zumrut Ceren OZDUMAN, Burcu OGLAKCI OZKOC, Evrim ELIGUZELOGLU DALKILIC
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Oguz Kaan Tuysuz, Merve Gurses
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Elif İpek KILIÇ DÖNMEZ, İhsan HUBBEZOĞLU
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Merve Nur Yilmaz, Pinar Gul
BMC Oral Health.2024;[Epub] CrossRef
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KG Garcia, GP Nunes, ACB Delbem, PH dos Santos, GLP Fernandes, HF Robles, PBB Lemos, M Danelon
Operative Dentistry.2024; 49(4): 465. CrossRef
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Sultan Aktuğ Karademir, Samet Atasoy, Beyza Yılmaz
BMC Oral Health.2024;[Epub] CrossRef
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Leszek Szalewski, Dorota Wójcik, Monika Sowa, Vladyslav Vivcharenko, Krzysztof Pałka
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In Vitro Evaluation of the Effectiveness and pH Variation of Dental Bleaching Gels and Their Effect on Enamel Surface Roughness
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Does the combination of whitening toothpaste and hydrogen peroxide bleaching increase the surface roughness and change the morphology of a nanofilled composite?
Cecília Pereira da Silva Braga Tenório, Matheus Kury, Geyse Maria dos Santos Muniz Mota, Cecília Pedroso Turssi, Flávia Lucisano Botelho do Amaral, Vanessa Cavalli
Brazilian Journal of Oral Sciences.2024; 23: e241938. CrossRef
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Majed M. Alsarani, Aftab Ahmed Khan, Leonel S. J. Bautista, Hanan Alsunbul, Jukka P. Matinlinna
European Journal of Oral Sciences.2024;[Epub] CrossRef
Effect of Repolishing on Color Stability, Translucency, and Surface Roughness of Aged Monochromatic Dental Composites
Mohamed M. Abdul-Monem, Mohamed A. Hussein, Mona G. Abdelrehim
European Journal of General Dentistry.2024; 13(03): 240. CrossRef
Color changes of nanofiller composite resin after glycerin application immersed in turmeric extract
Sukaton, Galih Sampoerno, Widyajeng Ayu Laksmi, Daradhasih Bestari Santiaji
Conservative Dentistry Journal.2023; 13(1): 37. CrossRef
Effects of Dental Bleaching Agents on the Surface Roughness of Dental Restoration Materials
Alexandru Dan Popescu, Mihaela Jana Tuculina, Oana Andreea Diaconu, Lelia Mihaela Gheorghiță, Claudiu Nicolicescu, Cristian Niky Cumpătă, Cristiana Petcu, Jaqueline Abdul-Razzak, Ana Maria Rîcă, Ruxandra Voinea-Georgescu
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Sushritha Sricharan, Swaroop Hegde, Narmada J., Indiresha H. Narayana, Chatura Mohan, Nithin K. Shetty
Journal of Advanced Oral Research.2023; 14(2): 190. CrossRef
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Ruwaida Z Alshali, Mohammed A AlQahtani, Dalea M Bukhary, Mlak A Alzahrani, Shatha S Alsoraihi, Majed A Alqahtani
Journal of Applied Biomaterials & Functional Materials.2023;[Epub] CrossRef
Effect of bleaching with 15% carbamide peroxide on color stability of microhybrid, nanohybrid, and nanofilled resin composites, each in 3 staining solutions (coffee, cola, red grape juice): A 3-phase study
Azadeh Ghaemi, Sanaz Sharifishoshtari, Mohsen Shahmoradi, Hossein Akbari, Parisa Boostanifard, Sepideh Bagheri, Mohammadreza Shokuhifar, Negin Ashoori, Vahid Rakhshan
Dental Research Journal.2023;[Epub] CrossRef
Micro-Hardness and Surface Roughness of Bulk-Fill Composite Resin: Effect of Surface Sealant Application and Two Bleaching Regimens
Reham Mohamad Attia, Eman Mohamed Sobhy, Mona El Said Abd El Hameed Essa
European Journal of General Dentistry.2023; 12(03): 169. CrossRef
Shear bond strength after using sealant before bonding: a systematic review and meta-analysis of in vitro studies
Jennifer Hoppe, Thomas Lehmann, Christoph-Ludwig Hennig, Ulrike Schulze-Späte, Collin Jacobs
Clinical Oral Investigations.2022; 26(1): 1. CrossRef
Effect of 16% Carbamide Peroxide and Activated-Charcoal-Based Whitening Toothpaste on Enamel Surface Roughness in Bovine Teeth: An In Vitro Study
Jorge Zamudio-Santiago, Marysela Ladera-Castañeda, Flor Santander-Rengifo, Carlos López-Gurreonero, Alberto Cornejo-Pinto, Ali Echavarría-Gálvez, Luis Cervantes-Ganoza, César Cayo-Rojas
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Direct dentin bleaching: Would it be possible?
Camila Ferro Clemente, Sibele de Alcântara, Lívia Maria Alves Valentim da Silva, Lara Maria Bueno Esteves, Anderson Catelan, Karen Milaré Seiscento Aidar, Ticiane Cestari Fagundes, André Luiz Fraga Briso
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EFFECT OF İN-OFFİCE BLEACHİNG ON THE SURFACE ROUGHNESS OF DİFFERENT COMPOSİTE RESİNS
Seher KAYA, Ozden OZEL BEKTAS
Cumhuriyet Dental Journal.2022; 25(Supplement): 78. CrossRef
Effect of Polishing on the Surface Microhardness of Nanohybrid Composite Resins Subjected to 35% Hydrogen Peroxide
Giovanna Gisella Ramírez-Vargas, Julia Elbia Medina y Mendoza, Ana Sixtina Aliaga-Mariñas, Marysela Irene Ladera-Castañeda, Luis Adolfo Cervantes-Ganoza, César Félix Cayo-Rojas
Journal of International Society of Preventive and Community Dentistry.2021; 11(2): 216. CrossRef
Intrapulpal Concentration of Hydrogen Peroxide of Teeth Restored With Bulk Fill and Conventional Bioactive Composites
DP Silva, BA Resende, M Kury, CB André, CPM Tabchoury, M Giannini, V Cavalli
Operative Dentistry.2021; 46(3): E158. CrossRef
An Environmental Scanning Electron Microscopy Evaluation on Comparison of Three Different Bleaching Agents using the Laser Activated in-Office Bleaching at Different Wavelengths
Shachi Goenka, Sushil Kumar Cirigiri, Kanika Poplai, Baig Mirza Aslam, Shalini Singh, Shweta Gangavane
Journal of Pharmacy and Bioallied Sciences.2021; 13(Suppl 2): S1478. CrossRef
Effects of Artificial Staining and Bleaching Protocols on the Surface Roughness, Color, and Whiteness Changes of an Aged Nanofilled Composite
Geyse Maria dos Santos Muniz Mota, Matheus Kury, Cecília Pereira da Silva Braga Tenório, Flávia Lucisano Botelho do Amaral, Cecília Pedroso Turssi, Vanessa Cavalli
Frontiers in Dental Medicine.2020;[Epub] CrossRef

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The effect of individualization of fiberglass posts using bulk-fill resin-based composites on cementation: an in vitro study: Rodrigo Barros Esteves Lins, Jairo Matozinho Cordeiro, Carolina Perez Rangel, Thiago Bessa Marconato Antunes, Luís Roberto Marcondes Martins; Restor Dent Endod 2019;44(4):e37. Published online October 18, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e37

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Objectives

This study evaluated the bond strength of various fiberglass post cementation techniques using different resin-based composites.

Materials and Methods

The roots from a total of 100 bovine incisors were randomly assigned to 5 treatment groups: G1, post + Scotchbond Multi-Purpose (SBMP) + RelyX ARC luting agent; G2, relined post (Filtek Z250) + SBMP + RelyX ARC; G3, individualized post (Filtek Z250) + SBMP; G4, individualized post (Filtek Bulk-Fill) + SBMP; G5, individualized post (Filtek Bulk-Fill Flow) + SBMP. The samples were subjected to the push-out (n = 10) and pull-out (n = 10) bond strength tests. Data from the push-out bond strength test were analyzed using 2-way analysis of variance (ANOVA) with the Bonferroni post hoc test, and data from the pull-out bond strength test were analyzed using 1-way ANOVA.

Results

The data for push-out bond strength presented higher values for G2 and G5, mainly in the cervical and middle thirds, and the data from the apical third showed a lower mean push-out bond strength in all groups. No significant difference was noted for pull-out bond strength among all groups. The most frequent failure modes observed were adhesive failure between dentine and resin and mixed failure.

Conclusions

Fiberglass post cementation using restorative and flowable bulk-fill composites with the individualization technique may be a promising alternative to existing methods of post cementation.

Citations

Citations to this article as recorded by

Effects of a relined fiberglass post with conventional and self-adhesive resin cement
Wilton Lima dos Santos Junior, Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Luís Roberto Marcondes Martins
Restorative Dentistry & Endodontics.2024;[Epub] CrossRef
Fracture resistance of weakened roots restored with relined or milled CAD-CAM glass fiber posts
Belizane das Graças Oliveira MAIA, Thais da Silva Alves SANTOS, Cláudio Antonio Talge CARVALHO, Francielle Silvestre VERNER, Rafael Binato JUNQUEIRA
Dental Materials Journal.2023; 42(1): 92. CrossRef
Evaluation of pretreatments on intra‐radicular dentin bond strength of self‐adhesive resin cements
Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Beatriz Ometto Sahadi, Luís Roberto Marcondes Martins, Jorge Rodrigo Soto‐Montero
Journal of Esthetic and Restorative Dentistry.2022; 34(7): 1051. CrossRef
Comparison of the Mechanical Properties and Push-out Bond Strength of Self-adhesive and Conventional Resin Cements on Fiber Post Cementation
MR Santi, RBE Lins, BO Sahadi, JR Soto-Montero, LRM Martins
Operative Dentistry.2022; 47(3): 346. CrossRef
Glass fiber posts
Renata Pereira, Rodrigo Barros Esteves Lins, Victória Castelan Rodrigues, Débora Alves Nunes Leite Lima, Luís Roberto Marcondes Martins, Flávio Henrique Baggio Aguiar
Brazilian Journal of Oral Sciences.2020; 19: e207508. CrossRef

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Case Report

Pulp revascularization with and without platelet-rich plasma in two anterior teeth with horizontal radicular fractures: a case report: Edison Arango-Gómez, Javier Laureano Nino-Barrera, Gustavo Nino, Freddy Jordan, Henry Sossa-Rojas; Restor Dent Endod 2019;44(4):e35. Published online August 20, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e35

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Pulp revascularization is an alternative treatment in immature traumatized teeth with necrotic pulp. However, this procedure has not been reported in horizontal root fractures. This is a case report of a 9-year-old patient with multiple horizontal root fractures in 2 upper central incisors that were successfully treated with pulp revascularization. The patient presented for treatment 2 years after the initial trauma, and revascularization was attempted after the initial treatment with calcium hydroxide had failed. Prior to pulp revascularization, cone-beam computed tomography and autoradiograms demonstrated multiple horizontal fractures in the middle and apical thirds of the roots of the 2 affected teeth. Revascularization was performed in both teeth; platelet-rich plasma (PRP) was used in one tooth (#11) and the conventional method (blood clot) was used in the other tooth (#21). Clinical and radiographic follow-up over 4 years demonstrated pulp calcification in the PRP-treated tooth. Neither of the 2 teeth were lost, and the root canal calcification of tooth #11 was greater than that of tooth #21. This case suggests that PRP-based pulp revascularization may be an alternative for horizontal root fractures.

Citations

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Dental pulp mesenchymal stem cells-response to fibrin hydrogel reveals ITGA2 and MMPs expression
David Tong, Stéphanie Gobert, Alicia Reuzeau, Jean-Christophe Farges, Marianne Leveque, Marie Bolon, Arthur Costantini, Marielle Pasdeloup, Jérôme Lafont, Maxime Ducret, Mourad Bekhouche
Heliyon.2024; 10(13): e32891. CrossRef
Pulp regeneration treatment using different bioactive materials in permanent teeth of pediatric subjects
Dina Abdellatif, Alfredo Iandolo, Giuseppina De Benedetto, Francesco Giordano, Davide Mancino, Edouard Euvrard, Massimo Pisano
Journal of Conservative Dentistry and Endodontics.2024; 27(5): 458. CrossRef
Retreatment of a Failed Regenerative Endodontic Treatment in an Immature Tooth with a Horizontal Root Fracture: A Case Report
Zaher Marjy, Iris Slutzky-Goldberg
International Journal of Clinical Pediatric Dentistry.2024; 17(10): 1168. CrossRef
The Impact of the Preferred Reporting Items for Case Reports in Endodontics (PRICE) 2020 Guidelines on the Reporting of Endodontic Case Reports
Sofian Youssef, Phillip Tomson, Amir Reza Akbari, Natalie Archer, Fayjel Shah, Jasmeet Heran, Sunmeet Kandhari, Sandeep Pai, Shivakar Mehrotra, Joanna M Batt
Cureus.2023;[Epub] CrossRef
Evaluation of postoperative pain and healing following regenerative endodontics using platelet‐rich plasma versus conventional endodontic treatment in necrotic mature mandibular molars with chronic periapical periodontitis. A randomized clinical trial
Yassmin Elsayed Ahmed, Geraldine Mohamed Ahmed, Angie Galal Ghoneim
International Endodontic Journal.2023; 56(4): 404. CrossRef
Regenerative endodontic procedures for two traumatized mature anterior teeth with transverse root fractures
Jing Lu, Bill Kahler
BMC Oral Health.2022;[Epub] CrossRef
Are platelet concentrate scaffolds superior to traditional blood clot scaffolds in regeneration therapy of necrotic immature permanent teeth? A systematic review and meta-analysis
Qianwei Tang, Hua Jin, Song Lin, Long Ma, Tingyu Tian, Xiurong Qin
BMC Oral Health.2022;[Epub] CrossRef
Platelet-Rich Fibrin Used as a Scaffold in Pulp Regeneration: Case Series
Ceren ÇİMEN, Selin ŞEN, Elif ŞENAY, Tuğba BEZGİN
Cumhuriyet Dental Journal.2021; 24(1): 113. CrossRef
Plasma rico en plaquetas en Odontología: Revisión de la literatura
Hugo Anthony Rosas Rozas, Hugo Leoncio Rosas Cisneros
Yachay - Revista Científico Cultural.2021; 10(1): 536. CrossRef

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Review Article

Effect of calcium hydroxide on inflammatory root resorption and ankylosis in replanted teeth compared with other intracanal materials: a review: Maryam Zare Jahromi, Mahmood Reza Kalantar Motamedi; Restor Dent Endod 2019;44(3):e32. Published online August 1, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e32

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Calcium hydroxide (CH) is the gold-standard intracanal dressing for teeth subjected to traumatic avulsion. A common complication after the replantation of avulsed teeth is root resorption (RR). The current review was conducted to compare the effect of CH with that of other intracanal medications and filling materials on inflammatory RR and replacement RR (ankylosis) in replanted teeth. The PubMed and Scopus databases were searched through June 2018 using specific keywords related to the title of the present article. The materials that were compared to CH were in 2 categories: 1) mineral trioxide aggregate (MTA) and endodontic sealers as permanent filling materials for single-visit treatment, and 2) Ledermix, bisphosphonates, acetazolamide, indomethacin, gallium nitrate, and enamel matrix-derived protein (Emdogain) as intracanal medicaments for multiple-visit management of avulsed teeth prior to the final obturation. MTA can be used as a single-visit root filling material; however, there are limited data on its efficacy due to a lack of clinical trials. Ledermix and acetazolamide were comparable to CH in reducing RR. Emdogain seems to be an interesting material, but the data supporting its use as an intracanal medication remain very limited. The conclusions drawn in this study were limited by the insufficiency of clinical trials.

Citations

Citations to this article as recorded by

Efficacy of Simvastatin in Inhibiting Bone Resorption and Promoting Healing in Delayed Tooth Avulsion: A Case Series
Rajesh Kumar, Supraja N Atluri, Alekhya Achanta, Chittaranjan Bogishetty, Tejaswini R Chunduri, Tejaswini PSS, Ramakrishna Ravi
Cureus.2025;[Epub] CrossRef
Bioactive potential of Bio-C Temp demonstrated by systemic mineralization markers and immunoexpression of bone proteins in the rat connective tissue
Camila Soares Lopes, Mateus Machado Delfino, Mário Tanomaru-Filho, Estela Sasso-Cerri, Juliane Maria Guerreiro-Tanomaru, Paulo Sérgio Cerri
Journal of Materials Science: Materials in Medicine.2024;[Epub] CrossRef
The use of mineral trioxide aggregate for treatment of children with complications of dental trauma
L.Yu. Kharkova, M.V. Korolenkova
Stomatology.2024; 103(4): 59. CrossRef
Instant Re-Implantation of Avulsed Teeth
Smita Paul, Sambarta Das, Nirmal Debbarma, Barun Dasgupta, Bidyut Seal, Ayesha Satapathy
Journal of Pharmacy and Bioallied Sciences.2024; 16(Suppl 4): S3461. CrossRef
Interpretation by literature review of the use of calcium hydroxide as an intra-ductal medication
María Belén Muñoz Padilla, Verónica Alicia Vega Martínez, Camila Alejandra Villafuerte Moya
Salud, Ciencia y Tecnología.2024; 4: 924. CrossRef
Evaluation of the physicochemical properties of intracanal medications used in traumatized teeth
Patricia Almeida da Silva de Macedo, Walbert de Andrade Vieira, Paulo Henrique Gabriel, Karla de Faria Vasconcelos, Francisco Haiter Neto, Ana Carolina Correia Laurindo de Cerqueira Neto, Brenda Paula Figueiredo de Almeida Gomes, Marcos Roberto dos Santo
Brazilian Journal of Oral Sciences.2024; 23: e242997. CrossRef
Treatment of Teeth with Root Resorptions: A Case Report and Systematic Review
Damla Erkal, Abdullah Başoğlu, Damla Kırıcı, Nezahat Arzu Kayar, Simay Koç, Kürşat Er
Galician Medical Journal.2023;[Epub] CrossRef
Successful outcome of permanent maxillary incisor reimplanted after 30 hours of extra‐oral time—a case report with 5‐year follow‐up
Ibadat Preet Kaur, Ashok Kumar, Mukul Kumar, Kanistika Jha
Clinical Case Reports.2023;[Epub] CrossRef
Replantation of an Avulsed Tooth: A Case Report
Nishad Kadulkar, Rubi Kataki, Adrija Deka, Salouno Thonai
Cureus.2023;[Epub] CrossRef
Avulsion of Permanent Mandibular Incisors: A Report of Two Cases with Pertinent Literature
Ibadat Preet Kaur, Jitendra Sharan, Pallawi Sinha, Ashok Kumar, Anand Marya, Leandro Napier de Souza
Case Reports in Dentistry.2023; 2023: 1. CrossRef
The Impact of Autologous Platelet Concentrates on the Periapical Tissues and Root Development of Replanted Teeth: A Systematic Review
Zohaib Khurshid, Faris Yahya I. Asiri, Shariq Najeeb, Jithendra Ratnayake
Materials.2022; 15(8): 2776. CrossRef

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Research Articles

Discoloration of teeth due to different intracanal medicaments: Farzaneh Afkhami, Sadaf Elahy, Alireza Mahmoudi Nahavandi, Mohamad Javad Kharazifard, Aidin Sooratgar; Restor Dent Endod 2019;44(1):e10. Published online February 12, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e10

Abstract PDF PubReader ePub

Objectives

The objective of this study was to assess coronal discoloration induced by the following intracanal medicaments: calcium hydroxide (CH), a mixture of CH paste and chlorhexidine gel (CH/CHX), and triple antibiotic paste (3Mix).

Materials and Methods

Seventy extracted single-canal teeth were selected. Access cavities were prepared and each canal was instrumented with a rotary ProTaper system. The specimens were randomly assigned to CH, CH/CHX, and 3Mix paste experimental groups (n = 20 each) or a control group (n = 10). Each experimental group was randomly divided into 2 subgroups (A and B). In subgroup A, medicaments were only applied to the root canals, while in subgroup B, the root canals were completely filled with medicaments and a cotton pellet dipped in medicament was also placed in the pulp chamber. Spectrophotometric readings were obtained from the mid-buccal surface of the tooth crowns immediately after placing the medicaments (T1) and at 1 week (T2), 1 month (T3), and 3 months (T4) after filling. The ∆E was then calculated. Data were analyzed using 2-way analysis of variance (ANOVA), 3-way ANOVA, and the Scheffé post hoc test.

Results

The greatest color change (ΔE) was observed at 3 months (p < 0.0001) and in 3Mix subgroup B (p = 0.0057). No significant color change occurred in the CH (p = 0.7865) or CH/CHX (p = 0.1367) groups over time, but the 3Mix group showed a significant ΔE (p = 0.0164).

Conclusion

Intracanal medicaments may induce tooth discoloration. Use of 3Mix must be short and it must be carefully applied only to the root canals; the access cavity should be thoroughly cleaned afterwards.

Citations

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Effects of Intra-canal Medicaments on Infrared Light Energy Transmission Through Enamel and Dentin During Photobiomodulation: An In Vitro Study
Sachin Kulkarni, Laurence J. Walsh, Yash Bhurani, Roy George
Journal of Endodontics.2025;[Epub] CrossRef
Effect of Calcium Hydroxide Versus Double Antibiotic Paste on Endodontic Treatment Outcomes in Teeth With Large Periapical Lesions: A Triple‐Blind Randomized Clinical Trial
Afsaneh Rahmati, Farshad Seyedein, Omid Dianat, Sara Saedi, Golriz Rostami, Alireza Akbarzadeh Baghban, Shima Sabertahan, Majid Kazem, Kee Y. Kum
International Journal of Dentistry.2024;[Epub] CrossRef
The effect of different intracanal irrigants on the push-out bond strength of dentin in damaged anterior primary teeth
Leila Bassir, Shirin Taravati, Farzad Nouri, Saeide Rahimi
Journal of Medicine and Life.2024; 17(5): 536. CrossRef
In Vıtro Evaluatıon of Dıscoloratıon Caused by Root Canal Sealers and Color Changes after Bleachıng
Emre Bodrumlu, Esma Dinger
Annals of Dental Specialty.2024; 12(1): 77. CrossRef
The effect of four different intracanal medicaments on the push-out bond strength of root canal sealers
Shalu Maan, Vijaya Dhar Bhatt, Rohit Singh, Sayak Gupta, Syed Alay Noorain, Aashna Gill, Pradeep Kumar, Sushil Yadav, Preeti Sharma
Journal of Medicine and Life.2022; 15(4): 448. CrossRef
Effect of hydrogel-based antibiotic intracanal medicaments on crown discoloration
Rayan B. Yaghmoor, Jeffrey A. Platt, Kenneth J. Spolnik, Tien Min Gabriel Chu, Ghaeth H. Yassen
Restorative Dentistry & Endodontics.2021;[Epub] CrossRef

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Evaluation of the effects of whitening mouth rinses combined with conventional tooth bleaching treatments: Jaqueline Costa Favaro, Omar Geha, Ricardo Danil Guiraldo, Murilo Baena Lopes, Andreza Maria Fábio Aranha, Sandrine Bittencourt Berger; Restor Dent Endod 2019;44(1):e6. Published online January 30, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e6

Abstract PDF PubReader ePub

Objectives

The aim of the present study was to evaluate the effect of whitening mouth rinses alone and in combination with conventional whitening treatments on color, microhardness, and surface roughness changes in enamel specimens.

Materials and Methods

A total of 108 enamel specimens were collected from human third molars and divided into 9 groups (n = 12): 38% hydrogen peroxide (HP), 10% carbamide peroxide (CP), 38% HP + Listerine Whitening (LW), 10% CP + LW, 38% HP + Colgate Plax Whitening (CPW), 10% CP + CPW, LW, CPW, and the control group (CG). The initial color of the specimens was measured, followed by microhardness and roughness tests. Next, the samples were bleached, and their color, microhardness, and roughness were assessed. Data were analyzed through 2-way analysis of variance (ANOVA; microhardness and roughness) and 1-way ANOVA (color change), followed by the Tukey post hoc test. The Dunnett test was used to compare the roughness and microhardness data of the CG to those of the treated groups.

Results

Statistically significant color change was observed in all groups compared to the CG. All groups, except the LW group, showed statistically significant decreases in microhardness. Roughness showed a statistically significant increase after the treatments, except for the 38% HP group.

Conclusions

Whitening mouth rinses led to a whitening effect when they were used after conventional treatments; however, this process caused major changes on the surface of the enamel specimens.

Citations

Citations to this article as recorded by

Which Whitening Mouthwash With Different Ingredients Is More Effective on Color and Bond Strength of Enamel?
Elif Varli Tekingur, Fatih Bedir, Muhammet Karadas, Rahime Zeynep Erdem
Journal of Esthetic and Restorative Dentistry.2024;[Epub] CrossRef
Do Different Tooth Bleaching–Remineralizing Regimens Affect the Bleaching Effectiveness and Enamel Microhardness In Vitro?
Hamideh Sadat Mohammadipour, Parnian Shokrollahi, Sima Gholami, Hosein Bagheri, Fatemeh Namdar, Salehe Sekandari, Cesar Rogério Pucci
International Journal of Dentistry.2024;[Epub] CrossRef
Effect of hydrogen peroxide versus charcoal-based whitening mouthwashes on color, surface roughness, and color stability of enamel
Mayada S. Sultan
BMC Oral Health.2024;[Epub] CrossRef
Effects of online marketplace-sourced over-the-counter tooth whitening products on the colour, microhardness, and surface topography of enamel: an in vitro study
Radhika Agarwal, Nikki Vasani, Urmila Sachin Mense, Niharika Prasad, Aditya Shetty, Srikant Natarajan, Arindam Dutta, Manuel S. Thomas
BDJ Open.2024;[Epub] CrossRef
Effect of Whitening Mouthwashes on Color Change and Enamel Mineralization: An In Vitro Study
Rosa Josefina Roncal Espinoza, José Alberto Castañeda Vía, Alexandra Mena-Serrano, Lidia Yileng Tay
World Journal of Dentistry.2023; 14(9): 739. CrossRef
Effectiveness and Adverse Effects of Over-the-Counter Whitening Products on Dental Tissues
Maiara Rodrigues de Freitas, Marynara Mathias de Carvalho, Priscila Christiane Suzy Liporoni, Ana Clara Borges Fort, Rodrigo de Morais e Moura, Rayssa Ferreira Zanatta
Frontiers in Dental Medicine.2021;[Epub] CrossRef
Renklendirilmiş kompozit rezinin renk değişimine ve yüzey pürüzlülüğüne beyazlatıcı ağız gargarasının etkisi
Şeref Nur MUTLU, Makbule Tuğba TUNCDEMIR
Selcuk Dental Journal.2020; 7(3): 435. CrossRef

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Case Report

Endodontic management of central incisor associated with large periapical lesion and fused supernumerary root: a conservative approach: Gautam P. Badole, Pratima R. Shenoi, Ameya Parlikar; Restor Dent Endod 2018;43(4):e44. Published online October 26, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e44

Abstract PDF PubReader ePub

Fusion and gemination are developmental anomalies of teeth that may require endodontic treatment. Fusion may cause various clinical problems related to esthetics, tooth spacing, and other periodontal complications. Additional diagnostic tools are required for the diagnosis and the treatment planning of fused tooth. The present case report describes a case of unilateral fusion of a supernumerary root to an upper permanent central incisor with large periapical lesion in which a conservative approach was used without extraction of supernumerary tooth and obturated with mineral trioxide aggregate to reach a favorable outcome.

Citations

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Fusion of a Tooth with a Supernumerary Tooth: A Case Report and Literature Review of 35 Cases
Tatsuya Akitomo, Satoru Kusaka, Momoko Usuda, Mariko Kametani, Ami Kaneki, Taku Nishimura, Masashi Ogawa, Chieko Mitsuhata, Ryota Nomura
Children.2023; 11(1): 6. CrossRef
Approche multidisciplinaire d’un cas de fusion incisive centrale maxillaire avec un « talon cusp »
Sonia Terbeche, Kheira Yousfi, Samia Saddat, Souad Larbi Messaoudi, Noureddine Ahmed Fouatih, G. Mer, O. Weissenbach
Revue d'Orthopédie Dento-Faciale.2022; 56(2): 205. CrossRef

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Research Articles

Effects of a bleaching agent on properties of commercial glass-ionomer cements: Fernanda Lúcia Lago de Camargo, Ailla Carla Lancellotti, Adriano Fonseca de Lima, Vinícius Rangel Geraldo Martins, Luciano de Souza Gonçalves; Restor Dent Endod 2018;43(3):e32. Published online July 5, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e32

Abstract PDF PubReader ePub

Objectives

This study evaluated the effects of a bleaching agent on the composition, mechanical properties, and surface topography of 6 conventional glass-ionomer cements (GICs) and one resin-modified GIC.

Materials and Methods

For 3 days, the specimens were subjected to three 20-minute applications of a 37% H₂O₂-based bleaching agent and evaluated for water uptake (WTK), weight loss (WL), compressive strength (CS), and Knoop hardness number (KHN). Changes in surface topography and chemical element distribution were also analyzed by energy-dispersive X-ray spectroscopy and scanning electron microscopy. For statistical evaluation, the Kruskal-Wallis and Wilcoxon paired tests (α = 0.05) were used to evaluate WTK and WL. CS specimens were subjected to 2-way analysis of variance (ANOVA) and the Tukey post hoc test (α = 0.05), and KH was evaluated by one-way ANOVA, the Holm-Sidak post hoc test (α = 0.05), and the t-test for independent samples (α = 0.05).

Results

The bleaching agent increased the WTK of Maxxion R, but did not affect the WL of any GICs. It had various effects on the CS, KHN, surface topography, and the chemical element distribution of the GICs.

Conclusions

The bleaching agent with 37% H₂O₂ affected the mechanical and surface properties of GICs. The extent of the changes seemed to be dependent on exposure time and cement composition.

Citations

Citations to this article as recorded by

Physical-mechanical, chemical and biological properties of graphene-reinforced glass ionomer cements
Tatiane Ramos dos Santos Jordão, Laura Soares Viana Fernandes, Karla Lorene de França Leite, Adílis Alexandria, Emmanuel João Nogueira Leal Silva, Lucianne Cople Maia, Tatiana Kelly da Silva Fidalgo
Restorative Dentistry & Endodontics.2024;[Epub] CrossRef
An In Vitro Exploration of Interaction Mechanisms of Intracoronal Bleaching on the Compressive Strength of Conventional and Calcium Silicate–Based Self‐Adhesive Resins and Their Bonding to Composite Resin Restorative Material
Fereshteh Shafiei, Paria Dehghanian, Shadi Tivay, Yasamin Ghahramani, Luca Testarelli
International Journal of Dentistry.2024;[Epub] CrossRef
Multidisciplinary conservative management of a severely discolored nonvital tooth
Álvaro Ferrando Cascales, Francesc Abella Sans, Rubén Agustín-Panadero, José Amengual Lorenzo
The Journal of Prosthetic Dentistry.2023;[Epub] CrossRef
Éclaircissement dentaire
V. Pilliol, B. Ballester, T. Baudinet, G. Aboudharama, E. Terrer
EMC - Odontologie.2023; 39(2): 1. CrossRef
The Effect of Home and In-Office Bleaching on Microhardness and Color of Different CAD/CAM Ceramic Materials
Ruwaida Z. Alshali, Mohammed A. Alqahtani
Materials.2022; 15(17): 5948. CrossRef
Éclaircissement dentaire
V. Pilliol, B. Ballester, T. Baudinet, G. Aboudharama, E. Terrer
EMC - Médecine buccale.2022; 15(4): 1. CrossRef
Éclaircissement dentaire
V. Pilliol, B. Ballester, T. Baudinet, G. Aboudharam, E. Terrer
EMC - Orthopédie dentofaciale.2022; 34(1): 1. CrossRef
Comparative Evaluation of Two Glass Polyalkenoate Cements: An In Vivo Pilot Study Using a Sheep Model
Leyla Hasandoost, Daniella Marx, Paul Zalzal, Oleg Safir, Mark Hurtig, Cina Mehrvar, Stephen D. Waldman, Marcello Papini, Mark R. Towler
Journal of Functional Biomaterials.2021; 12(3): 44. CrossRef
The Effect of Simulated Field Storage Conditions on Dental Restorative Materials for Military Field Use
David J Lemon, Wen Chen, Trevor Smith, April A Ford, Steven X Moffett, Jeffrey T Hoyle, Nicholas J Hamlin, Yoon Y Hwang
Military Medicine.2020; 185(5-6): e831. CrossRef

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Effect of various bleaching treatments on shear bond strength of different universal adhesives and application modes: Fatma Dilsad Oz, Zeynep Bilge Kutuk; Restor Dent Endod 2018;43(2):e20. Published online April 16, 2018; DOI: https://doi.org/10.5395/rde.2018.43.e20

Abstract PDF PubReader ePub

Objectives

The aim of this in vitro study was to evaluate the bond strength of 2 universal adhesives used in different application modes to bleached enamel.

Materials and Methods

Extracted 160 sound human incisors were used for the study. Teeth were divided into 4 treatment groups: No treatment, 35% hydrogen peroxide, 16% carbamid peroxide, 7.5% carbamid peroxide. After bleaching treatments, groups were divided into subgroups according to the adhesive systems used and application modes (n = 10): 1) Single Bond Universal, etch and rinse mode; 2) Single Bond Universal, self-etch mode; 3) Gluma Universal, etch and rinse mode; 4) Gluma Universal, self-etch mode. After adhesive procedures nanohybrid composite resin cylinders were bonded to the enamel surfaces. All specimens were subjected to shear bond strength (SBS) test after thermocycling. Data were analyzed using a 3-way analysis of variance (ANOVA) and Tukey post hoc test.

Results

No significant difference were found among bleaching groups (35% hydrogen peroxide, 16% carbamid peroxide, 7.5% carbamid peroxide, and no treatment groups) in the mean SBS values. There was also no difference in SBS values between Single Bond Universal and Gluma Universal at same application modes, whereas self-etch mode showed significantly lower SBS values than etch and rinse mode (p < 0.05).

Conclusions

The bonding performance of the universal adhesives was enhanced with the etch and rinse mode application to bleached enamel and non-bleached enamel.

Citations

Citations to this article as recorded by

Effects of Time-Elapsed Bleaching on the Surface and Mechanical Properties of Dentin Substrate Using Hydrogen Peroxide-Free Nanohydroxyapatite Gel
Aftab Khan, Abdulaziz AlKhureif, Manal Almutairi, Abrar Nooh, Saeed Hassan, Yasser Alqahtani
International Journal of Nanomedicine.2024; Volume 19: 10307. CrossRef
Effect of sodium ascorbate on the shear bond strength of orthodontic brackets to bleached enamel using universal dental adhesive
Saeid Sadeghian, Kamyar Fathpour, Mahshid Biglari
Dental Research Journal.2023;[Epub] CrossRef
Quantitative Measurements of the Depth of Enamel Demineralization before and after Bleach: An In Vitro Study
Sara Naim, Gianrico Spagnuolo, Essam Osman, Syed Sarosh Mahdi, Gopi Battineni, Syed Saad B. Qasim, Mariangela Cernera, Hasna Rifai, Nada Jaafar, Elie Maalouf, Carina Mehanna Zogheib, Konstantinos Michalakis
BioMed Research International.2022;[Epub] CrossRef
DİŞ BEYAZLATMA İŞLEMİNİN LİTYUM DİSİLİKAT SERAMİĞİN BAĞLANMA DAYANIMINA ETKİSİ
Merve YILDIRAK, Rıfat GÖZNELİ
Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2020; : 1. CrossRef
The Effect of Different Bleaching Protocols, Used with and without Sodium Ascorbate, on Bond Strength between Composite and Enamel
Maroun Ghaleb, Giovanna Orsini, Angelo Putignano, Sarah Dabbagh, Georges Haber, Louis Hardan
Materials.2020; 13(12): 2710. CrossRef
Influence of phototherapy on adhesive strength and microleakage of bleached enamel bonded to orthodontic brackets: An in-vitro study
Erum Khan, Ibrahim Alshahrani, Muhammad Abdullah Kamran, Abdulaziz Samran, Ali Alqerban, Saad Abdul Rehman
Photodiagnosis and Photodynamic Therapy.2019; 25: 344. CrossRef
Effect of Er: YAG Laser on Microtensile Bond Strength of Bleached Dentin to Composite
Mohsen Rezaei, Elham Aliasghar, Mohammad Bagher Rezvani, Nasim Chiniforush, Zohreh Moradi
Journal of Lasers in Medical Sciences.2019; 10(2): 117. CrossRef

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