Restorative Dentistry & Endodontics

Research Articles

Pomegranate extract on eroded dentin: antioxidant action, bond strength and morphology of the adhesive interface after aging: Thiago Vinícius Cortez, Nathália Mancioppi Cerqueira, Julia Adornes Gallas, Wanderley Pereira Oliveira, Silmara Aparecida Milori Corona, Aline Evangelista Souza-Gabriel; Restor Dent Endod 2024;49(1):e9. Published online January 26, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e9

Objectives

This study aimed to evaluate the effect of pomegranate solution (Punica granatum) on eroded dentin through antioxidant action, shear bond strength (SBS) and interface morphology.

Materials and Methods

The 10% pomegranate peel extract was prepared by the lyophilization method. Punicalagin polyphenol was confirmed by high-performance liquid chromatography. Antioxidant activity was evaluated by capturing the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. For the SBS, 48 dentin fragments were divided into sound or eroded, and subdivided according to the pretreatment (n = 12): water or P. granatum. The surfaces were restored with self-etch adhesive and a bulk-fill resin (Ecosite; DMG). The SBS was done immediately (24 hours) and after thermal cycling + water storage (12 months). For scanning electron microscopy, 48 dentin fragments (24 sound and 24 eroded) received the same treatments as for SBS (n = 6), and they were analyzed after 24 hours and 12 months.

Results

The P. granatum had antioxidant action similar (p = 0.246) to the phenolic standard antioxidants. After 24 hours, eroded dentin had lower SBS than sound dentin (p < 0.001), regardless of the pretreatment. After 12 months, P. granatum maintained the SBS of sound dentin (13.46 ± 3.42 MPa) and eroded dentin (10.96 ± 1.90 MPa) statistically similar. The lowest values were found on eroded dentin treated with water (5.75 ± 1.65 MPa) (p < 0.001). P. granatum on eroded dentin caused peritubular demineralization and hybrid layer with resin tags.

Conclusions

The pomegranate extract had antioxidant action and preserved the adhesive interface of the eroded dentin.

Citations

Citations to this article as recorded by

Effect of pomegranate solution alone or combined with chlorhexidine against oral multispecies biofilm
J. A. Gallas, L. L. Pelozo, S. A. M. Corona, Y. Shen, M. Haapasalo, M. D. Sousa‐Neto, A. E. Souza‐Gabriel
International Endodontic Journal.2024; 57(12): 1819. CrossRef
The effect of resveratrol application on the micro-shear bond strength of adhesive to bleached enamel
Esra Cengiz-Yanardag, Izgen Karakaya
Scientific Reports.2024;[Epub] CrossRef

317 View
35 Download
2 Web of Science
2 Crossref

Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis: Julianne Coelho Silva, Edson Luiz Cetira Filho, Paulo Goberlânio de Barros Silva, Fábio Wildson Gurgel Costa, Vicente de Paulo Aragão Saboia; Restor Dent Endod 2022;47(2):e23. Published online May 6, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e23

Abstract PDF Supplementary Material PubReader ePub

Objectives

The aim of this investigation was to evaluate the effectiveness of collagen cross-linking agents (CCLAs) used in combination with the adhesive technique in restorative procedures.

Materials and Methods

In this systematic review, the authors followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. An electronic search was performed using PubMed, Scopus, Web of Science, Cochrane Library, LILACS, and DOSS, up to October 2020. The gray literature was also researched. Only randomized clinical trials were selected.

Results

The selection process yielded 3 studies from the 838 retrieved. The addition of CCLAs in the retention of restorations increased the number of events. The postoperative sensitivity scores and marginal adaptation scores showed no significant difference between the CCLA and control groups, and the marginal pigmentation scores showed a significant increase in the CCLA group. There were no caries events in any group throughout the evaluation period.

Conclusions

This systematic review showed that there is no clinical efficacy to justify the use of CCLAs in the protocols performed.

Citations

Citations to this article as recorded by

Riboflavin-ultraviolet-A collagen crosslinking treatments in improving dentin bonding and resistance to enzymatic digestion
Yung-Show Chiang, Ping-Ju Chen, Chun-Chan Ting, Yuh-Ling Chen, Shu-Fen Chuang
Journal of Dental Sciences.2025; 20(1): 109. CrossRef
Effect of dentin bio modifications and matrix metalloproteinase activity on bond strength – A systematic review and meta-analysis
D. Agarwal, S. R. Srinidhi, S. D. Aggarwal, P. Ingle, S. Tandon
Endodontics Today.2025; 23(1): 71. CrossRef
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations
Aline Honorato Damázio, Rosanna Tarkany Basting, Enrico Coser Bridi, Fabiana Mantovani Gomes França, Flávia Lucisano Botelho do Amaral, Cecilia Pedroso Turssi, Waldemir Francisco Vieira Junior, Roberta Tarkany Basting
Brazilian Journal of Oral Sciences.2024; 23: e244006. CrossRef
Effect of Collagen Crosslinkers on Dentin Bond Strength of Adhesive Systems: A Systematic Review and Meta-Analysis
Louis Hardan, Umer Daood, Rim Bourgi, Carlos Enrique Cuevas-Suárez, Walter Devoto, Maciej Zarow, Natalia Jakubowicz, Juan Eliezer Zamarripa-Calderón, Mateusz Radwanski, Giovana Orsini, Monika Lukomska-Szymanska
Cells.2022; 11(15): 2417. CrossRef

363 View
17 Download
3 Web of Science
4 Crossref

Review Article

Deep proximal margin rebuilding with direct esthetic restorations: a systematic review of marginal adaptation and bond strength: Hoda S. Ismail, Ashraf I. Ali, Rabab El. Mehesen, Jelena Juloski, Franklin Garcia-Godoy, Salah H. Mahmoud; Restor Dent Endod 2022;47(2):e15. Published online March 4, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e15

Search