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Nanoleakage of apical sealing using a calcium silicate-based sealer according to canal drying methods
Yoon-Joo Lee, Kyung-Mo Cho, Se-Hee Park, Yoon Lee, Jin-Woo Kim
Restor Dent Endod 2024;49(2):e20.   Published online April 19, 2024
DOI: https://doi.org/10.5395/rde.2024.49.e20
AbstractAbstract PDFPubReaderePub
Objectives

This study investigated the nanoleakage of root canal obturations using calcium silicate-based sealer according to different drying methods.

Materials and Methods

Fifty-two extracted mandibular premolars with a single root canal and straight root were selected for this study. After canal preparation with a nickel-titanium rotary file system, the specimens were randomly divided into 4 groups according to canal drying methods (1: complete drying, 2: blot drying/distilled water, 3: blot drying/NaOCl, 4: aspiration only). The root canals were obturated using a single-cone filling technique with a calcium silicate–based sealer. Nanoleakage was evaluated using a nanoflow device after 24 hours, 1 week, and 1 month. Data were collected twice per second at the nanoscale and measured in nanoliters per second. Data were statistically analyzed using the Kruskal-Wallis and Mann–Whitney U-tests (p < 0.05).

Results

The mean flow rate measured after 24 hours showed the highest value among the time periods in all groups. However, the difference in the flow rate between 1 week and 1 month was not significant. The mean flow rate of the complete drying group was the highest at all time points. After 1 month, the mean flow rate in the blot drying group and the aspiration group was not significantly different.

Conclusions

Within the limitations of this study, the canal drying method had a significant effect on leakage and sealing ability in root canal obturations using a calcium silicate-based sealer. Thus, a proper drying procedure is critical in endodontic treatment.

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A scientometric, bibliometric, and thematic map analysis of hydraulic calcium silicate root canal sealers
Anastasios Katakidis, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos
Restor Dent Endod 2023;48(4):e41.   Published online November 13, 2023
DOI: https://doi.org/10.5395/rde.2023.48.e41
AbstractAbstract PDFPubReaderePub
Objectives

This scientometric and bibliometric analysis explored scientific publications related to hydraulic calcium silicate-based (HCSB) sealers used in endodontology, aiming to describe basic bibliometric indicators and analyze current research trends.

Materials and Methods

A comprehensive search was conducted in Web of Science and Scopus using specific HCSB sealer and general endodontic-related terms. Basic research parameters were collected, including publication year, authorship, countries, institutions, journals, level of evidence, study design and topic of interest, title terms, author keywords, citation counts, and density.

Results

In total, 498 articles published in 136 journals were retrieved for the period 2008–2023. Brazil was the leading country, and the universities of Bologna in Italy and Sao Paolo in Brazil were represented equally as leading institutions. The most frequently occurring keywords were “calcium silicate,” “root canal sealer MTA-Fillapex,” and “biocompatibility,” while title terms such as “calcium,” “sealers,” “root,” “canal,” “silicate based,” and “endodontic” occurred most often. According to the thematic map analysis, “solubility” appeared as a basic theme of concentrated research interest, and “single-cone technique” was identified as an emerging, inadequately developed theme. The co-occurrence analysis revealed 4 major clusters centered on sealers’ biological and physicochemical properties, obturation techniques, retreatability, and adhesion.

Conclusions

This analysis presents bibliographic features and outlines changing trends in HCSB sealer research. The research output is dominated by basic science articles scrutinizing the biological and specific physicochemical properties of commonly used HCSB sealers. Future research needs to be guided by studies with a high level of evidence that utilize innovative, sophisticated technologies.

Citations

Citations to this article as recorded by  
  • Agri-Food Sector: Contemporary Trends, Possible Gaps, and Prospective Directions
    José Roberto Herrera Cantorani, Meire Ramalho de Oliveira, Luiz Alberto Pilatti, Thales Botelho de Sousa
    Metrics.2025; 2(1): 3.     CrossRef
  • Scientific mapping of experimental research on solar cookers: Global trends, evolution, and future directions
    Flavio Odoi-Yorke, Bismark Baah, Richard Opoku
    Solar Energy Advances.2025; 5: 100093.     CrossRef
  • A bibliometric analysis of global research trend and progress on Dy doped materials
    Sangeeta Kadyan, Manju Nain, Ashima Makhija, Poonam Punia, Anil Ohlan, Sajjan Dahiya, R. Punia, A.S. Maan
    Journal of Alloys and Compounds Communications.2024; 3: 100006.     CrossRef
  • Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs
    José Luis Sanz, Sergio López-García, David García-Bernal, Francisco Javier Rodríguez-Lozano, Leopoldo Forner, Adrián Lozano, Laura Murcia
    Clinical Oral Investigations.2024;[Epub]     CrossRef
  • Analyzing collaboration and impact: A bibliometric review of four highly published authors’ research profiles on collaborative maps
    Willy Chou, Julie Chi Chow
    Medicine.2024; 103(28): e38686.     CrossRef
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  • 14 Download
  • 2 Web of Science
  • 5 Crossref
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Effects of calcium silicate cements on neuronal conductivity
Derya Deniz-Sungur, Mehmet Ali Onur, Esin Akbay, Gamze Tan, Fügen Daglı-Comert, Taner Cem Sayın
Restor Dent Endod 2022;47(2):e18.   Published online March 7, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e18
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated alterations in neuronal conductivity related to calcium silicate cements (CSCs) by investigating compound action potentials (cAPs) in rat sciatic nerves.

Materials and Methods

Sciatic nerves were placed in a Tyrode bath and cAPs were recorded before, during, and after the application of test materials for 60-minute control, application, and recovery measurements, respectively. Freshly prepared ProRoot MTA, MTA Angelus, Biodentine, Endosequence RRM-Putty, BioAggregate, and RetroMTA were directly applied onto the nerves. Biopac LabPro version 3.7 was used to record and analyze cAPs. The data were statistically analyzed.

Results

None of the CSCs totally blocked cAPs. RetroMTA, Biodentine, and MTA Angelus caused no significant alteration in cAPs (p > 0.05). Significantly lower cAPs were observed in recovery measurements for BioAggregate than in the control condition (p < 0.05). ProRoot MTA significantly but transiently reduced cAPs in the application period compared to the control period (p < 0.05). Endosequence RRM-Putty significantly reduced cAPs.

Conclusions

Various CSCs may alter cAPs to some extent, but none of the CSCs irreversibly blocked them. The usage of fast-setting CSCs during apexification or regeneration of immature teeth seems safer than slow-setting CSCs due to their more favorable neuronal effects.

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Comparative analysis of bond strength to root dentin and compression of bioceramic cements used in regenerative endodontic procedures
Maykely Naara Morais Rodrigues, Kely Firmino Bruno, Ana Helena Gonçalves de Alencar, Julyana Dumas Santos Silva, Patrícia Correia de Siqueira, Daniel de Almeida Decurcio, Carlos Estrela
Restor Dent Endod 2021;46(4):e59.   Published online November 9, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e59
AbstractAbstract PDFPubReaderePub
Objectives

This study compared the Biodentine, MTA Repair HP, and Bio-C Repair bioceramics in terms of bond strength to dentin, failure mode, and compression.

Materials and Methods

Fifty-four slices obtained from the cervical third of 18 single-rooted human mandibular premolars were randomly distributed (n = 18). After insertion of the bioceramic materials, the push-out test was performed. The failure mode was analyzed using stereomicroscopy. Another set of cylindrically-shaped bioceramic samples (n = 10) was prepared for compressive strength testing. The normality of data distribution was analyzed using the Shapiro-Wilk test. The Kruskal-Wallis and Friedman tests were used for the push-out test data, while compressive strength was analyzed with analysis of variance and the Tukey test, considering a significance level of 0.05.

Results

Biodentine presented a higher median bond strength value (14.79 MPa) than MTA Repair HP (8.84 MPa) and Bio-C Repair (3.48 MPa), with a significant difference only between Biodentine and Bio-C Repair. In the Biodentine group, the most frequent failure mode was mixed (61%), while in the MTA Repair HP and Bio-C Repair groups, it was adhesive (94% and 72%, respectively). Biodentine showed greater resistance to compression (29.59 ± 8.47 MPa) than MTA Repair HP (18.68 ± 7.40 MPa) and Bio-C Repair (19.96 ± 3.96 MPa) (p < 0.05).

Conclusions

Biodentine showed greater compressive strength than MTA Repair HP and Bio-C Repair, and greater bond strength than Bio-C Repair. The most frequent failure mode of Biodentine was mixed, while that of MTA Repair HP and Bio-C Repair was adhesive.

Citations

Citations to this article as recorded by  
  • Comparación de la resistencia compresiva entre el Agregado Trióxido Mineral y BiodentineTM en perforaciones de furca de molares inferiores permanentes
    Jheymy Gerardo Huatuco-Granda, John Paul Torres-Navarro, Rosa Josefina Roncal-Espinoza
    Revista Facultad de Odontología.2024;[Epub]     CrossRef
  • Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
    Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
    Restorative Dentistry & Endodontics.2023;[Epub]     CrossRef
  • Evaluation the Marginal Adaptation for the Bio C Repair and Other Root end Filling Material by Using Scanning Electron Microscope (A Comparative In Vitro Study)
    Fatimah HAMADHİ, Zainab M.
    Cumhuriyet Dental Journal.2023; 26(3): 261.     CrossRef
  • Dentin Bond Strength of Calcium Silicate-Based Materials: A Systematic Review of In Vitro Studies
    Natalia Radulica, José Luis Sanz, Adrián Lozano
    Applied Sciences.2023; 14(1): 104.     CrossRef
  • Evaluation Of The Push-out Bond Strength Of The Bio-C Repair And Compare It With The Mineral Trioxide Aggregate And Amalgam When Used As Root-end Filling Material
    Fatimah R. Hammadi, Zainab M Abdul-Ameer
    Dental Hypotheses.2023; 14(2): 62.     CrossRef
  • Effect of different root canal irrigants on push-out bond strength of two novel root-end filling materials
    Nada Omar, Rasha M. Abdelraouf, Tamer M. Hamdy
    BMC Oral Health.2023;[Epub]     CrossRef
  • Effect of irrigation systems on the bond strength of calcium-silicate-based cement used as pulp barrier in regenerative endodontic treatment
    Cihan Hascizmeci, Burak Buldur
    Journal of Adhesion Science and Technology.2023; 37(23): 3393.     CrossRef
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Push-out bond strength and marginal adaptation of apical plugs with bioactive endodontic cements in simulated immature teeth
Maria Aparecida Barbosa de Sá, Eduardo Nunes, Alberto Nogueira da Gama Antunes, Manoel Brito Júnior, Martinho Campolina Rebello Horta, Rodrigo Rodrigues Amaral, Stephen Cohen, Frank Ferreira Silveira
Restor Dent Endod 2021;46(4):e53.   Published online October 20, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e53
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluates the bond strength and marginal adaptation of mineral trioxide aggregate (MTA) Repair HP and Biodentine used as apical plugs; MTA was used as reference material for comparison.

Materials and Methods

A total of 30 single-rooted teeth with standardized, artificially created open apices were randomly divided into 3 groups (n = 10 per group), according to the material used to form 6-mm-thick apical plugs: group 1 (MTA Repair HP); group 2 (Biodentine); and group 3 (white MTA). Subsequently, the specimens were transversely sectioned to obtain 2 (cervical and apical) 2.5-mm-thick slices per root. Epoxy resin replicas were observed under a scanning electron microscope to measure the gap size at the material/dentin interface (the largest and smaller gaps were recorded for each replica). The bond strength of the investigated materials to dentin was determined using the push-out test. The variable bond strengths and gap sizes were evaluated independently at the apical and cervical root dentin slices. Data were analyzed using descriptive and analytic statistics.

Results

The comparison between the groups regarding the variables' bond strengths and gap sizes showed no statistical difference (p > 0.05) except for a single difference in the smallest gap at the cervical root dentin slice, which was higher in group 3 than in group 1 (p < 0.05).

Conclusions

The bond strength and marginal adaptation to root canal walls of MTA HP and Biodentine cement were comparable to white MTA.

Citations

Citations to this article as recorded by  
  • Evaluation of the root dentin bond strength and intratubular biomineralization of a premixed calcium aluminate-based hydraulic bioceramic endodontic sealer
    Yu-Na Lee, Min-Kyeong Kim, Hee-Jin Kim, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
    Journal of Oral Science.2024; 66(2): 96.     CrossRef
  • Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
    Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira, Dr Karthikeyan Ramalingam
    International Journal of Dentistry.2024;[Epub]     CrossRef
  • Marginal adaptation of customized gutta percha cone with calcium silicate based sealer versus MTA and biodentine apical plugs in simulated immature permanent teeth (an in vitro study)
    Mary M. Mina, Sybel M. Moussa, Mahmoud R. Aboelseoud
    BMC Oral Health.2024;[Epub]     CrossRef
  • Comparative Evaluation of Push-Out Bond Strength of Conventional Mineral Trioxide Aggregate, Biodentine, a Modified Mineral Trioxide Aggregate, and Two Novel Antibacterial-Enhanced Mineral Trioxide Aggregates
    Arokia Rajkumar Shancy Merlin, Vignesh Ravindran, Ganesh Jeevanandan, Rajalakshmanan Eswaramoorthy, Abirami Arthanari
    Cureus.2024;[Epub]     CrossRef
  • Push out bond strength of hydraulic cements used at different thicknesses
    C. Ruiz Durán, Dra L. Gancedo-Caravia, V. Vera González, C. González Losada
    BMC Oral Health.2023;[Epub]     CrossRef
  • Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
    Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
    Restorative Dentistry & Endodontics.2023;[Epub]     CrossRef
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Micro-computed tomographic evaluation of single-cone obturation with three sealers
Sahar Zare, Ivy Shen, Qiang Zhu, Chul Ahn, Carolyn Primus, Takashi Komabayashi
Restor Dent Endod 2021;46(2):e25.   Published online April 16, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e25
AbstractAbstract PDFPubReaderePub
Objectives

This study used micro-computed tomography (µCT) to compare voids and interfaces in single-cone obturation among AH Plus, EndoSequence BC, and prototype surface pre-reacted glass ionomer (S-PRG) sealers and to determine the percentage of sealer contact at the dentin and gutta-percha (GP) interfaces.

Materials and Methods

Fifteen single-rooted human teeth were shaped using ProTaper NEXT size X5 rotary files using 2.5% NaOCl irrigation. Roots were obturated with a single-cone ProTaper NEXT GP point X5 with AH Plus, EndoSequence BC, or prototype S-PRG sealer (n = 5/group).

Results

The volumes of GP, sealer, and voids were measured in the region of 0–2, 2–4, 4–6, and 6–8 mm from the apex, using image analysis of sagittal µCT scans. GP volume percentages were: AH Plus (75.5%), EndoSequence BC (87.3%), and prototype S-PRG (94.4%). Sealer volume percentages were less: AH Plus (14.3%), EndoSequence BC (6.8%), and prototype S-PRG (4.6%). Void percentages were AH Plus (10.1%), EndoSequence BC (5.9%), and prototype S-PRG (1.0%). Dentin-sealer contact ratios of AH Plus, EndoSequence BC, and prototype S-PRG groups were 82.4% ± 6.8%, 71.6% ± 25.3%, and 70.2% ± 9.4%, respectively. GP-sealer contact ratios of AH Plus, EndoSequence BC, and prototype S-PRG groups were 65.6% ± 29.1%, 80.7% ± 25.8%, and 87.0% ± 8.6%, respectively.

Conclusions

Prototype S-PRG sealer created a low-void obturation, similar to EndoSequence BC sealer with similar dentin-sealer contact (> 70%) and GP-sealer contact (> 80%). Prototype S-PRG sealer presented comparable filling quality to EndoSequence BC sealer.

Citations

Citations to this article as recorded by  
  • Assessment of gap areas of root filling techniques in teeth with 3D-printed different configurations of C-shaped root canals: a micro-computed tomography study
    Tuba Gok, Adem Gok, Haydar Onur Aciksoz
    BMC Oral Health.2025;[Epub]     CrossRef
  • Assessment of isthmus filling using two obturation techniques performed by students with different levels of clinical experience
    Yang Yu, Chong-Yang Yuan, Xing-Zhe Yin, Xiao-Yan Wang
    Journal of Dental Sciences.2024; 19(1): 169.     CrossRef
  • Micro-CT determination of the porosity of two tricalcium silicate sealers applied using three obturation techniques
    Jinah Kim, Kali Vo, Gurmukh S. Dhaliwal, Aya Takase, Carolyn Primus, Takashi Komabayashi
    Journal of Oral Science.2024; 66(3): 163.     CrossRef
  • Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial
    Nawar Naguib Nawar, Mohamed Mohamed Elashiry, Ahmed El Banna, Shehabeldin Mohamed Saber, Edgar Schäfer
    Clinical Oral Investigations.2024;[Epub]     CrossRef
  • Hydraulic (Single Cone) Versus Thermogenic (Warm Vertical Compaction) Obturation Techniques: A Systematic Review
    Haytham S Jaha
    Cureus.2024;[Epub]     CrossRef
  • Sealing ability of various endodontic sealers with or without ethylenediaminetetraacetic acid (EDTA) treatment on bovine root canal
    Yusuke AIGAMI, Tomofumi SAWADA, Shunsuke SHIMIZU, Akiko ASANO, Mamoru NODA, Shinji TAKEMOTO
    Dental Materials Journal.2024; 43(3): 420.     CrossRef
  • A Literature Review of the Effect of Heat on the Physical-Chemical Properties of Calcium Silicate–Based Sealers
    Israa Ashkar, José Luis Sanz, Leopoldo Forner, James Ghilotti, María Melo
    Journal of Endodontics.2024; 50(8): 1044.     CrossRef
  • Assessment of the Prevalence of Head Lice Infestation and Parents’ Attitudes Towards Its Management: A School-based Epidemiological Study in İstanbul, Türkiye
    Özben Özden, İnci Timur, Hale Ezgi Açma, Duygu Şimşekli, Barış Gülerman, Özgür Kurt
    Turkish Journal of Parasitology.2023; 47(2): 112.     CrossRef
  • Calcium-doped zinc oxide nanocrystals as an innovative intracanal medicament: a pilot study
    Gabriela Leite de Souza, Thamara Eduarda Alves Magalhães, Gabrielle Alves Nunes Freitas, Nelly Xiomara Alvarado Lemus, Gabriella Lopes de Rezende Barbosa, Anielle Christine Almeida Silva, Camilla Christian Gomes Moura
    Restorative Dentistry & Endodontics.2022;[Epub]     CrossRef
  • Micro‐CT assessment of gap‐containing areas along the gutta‐percha‐sealer interface in oval‐shaped canals
    Gustavo De‐Deus, Gustavo O. Santos, Iara Zamboni Monteiro, Daniele M. Cavalcante, Marco Simões‐Carvalho, Felipe G. Belladonna, Emmanuel J. N. L. Silva, Erick M. Souza, Raphael Licha, Carla Zogheib, Marco A. Versiani
    International Endodontic Journal.2022; 55(7): 795.     CrossRef
  • A critical analysis of research methods and experimental models to study root canal fillings
    Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
    International Endodontic Journal.2022; 55(S2): 384.     CrossRef
  • Use of micro-CT to examine effects of heat on coronal obturation
    Ivy Shen, Joan Daniel, Kali Vo, Chul Ahn, Carolyn Primus, Takashi Komabayashi
    Journal of Oral Science.2022; 64(3): 224.     CrossRef
  • Obturation of Root Canals By Vertical Condensation of Gutta-Percha – Benefits and Pitfalls
    Calkovsky Bruno, Slobodnikova Ladislava, Bacinsky Martin, Janickova Maria
    Acta Medica Martiniana.2021; 21(3): 103.     CrossRef
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Interface between calcium silicate cement and adhesive systems according to adhesive families and cement maturation
Nelly Pradelle-Plasse, Caroline Mocquot, Katherine Semennikova, Pierre Colon, Brigitte Grosgogeat
Restor Dent Endod 2021;46(1):e3.   Published online December 9, 2020
DOI: https://doi.org/10.5395/rde.2021.46.e3
AbstractAbstract PDFPubReaderePub
Objectives

This study aimed to evaluate the interface between a calcium silicate cement (CSC), Biodentine and dental adhesives in terms of sealing ability.

Materials and Methods

Microleakage test: 160 standardized class II cavities were prepared on 80 extracted human molars. The cavities were filled with Biodentine and then divided into 2 experimental groups according to the time of restoration: composite resin obturation 15 minutes after Biodentine handling (D0); restoration after 7 days (D7). Each group was then divided into 8 subgroups (n = 5) according to the adhesive system used: etch-and-rinse adhesive (Prime & Bond); self-etch adhesive 2 steps (Optibond XTR and Clearfil SE Bond); self-etch adhesive 1 step (Xeno III, G-aenial Bond, and Clearfil Tri-S Bond); and universal used as etch-and-rinse or self-etch (ScotchBond Universal ER or SE). After thermocycling, the teeth were immersed in a silver nitrate solution, stained, longitudinally sectioned, and the Biodentine/adhesive percolation was quantified. Scanning electron microscopic observations: Biodentine/adhesive interfaces were observed.

Results

A tendency towards less microleakage was observed when Biodentine was etched (2.47%) and when restorations were done without delay (D0: 4.31%, D7: 6.78%), but this was not significant. The adhesives containing 10-methacryloyloxydecyl dihydrogen phosphate monomer showed the most stable results at both times studied. All Biodentine/adhesive interfaces were homogeneous and regular.

Conclusions

The good sealing of the CSC/adhesive interface is not a function of the system adhesive family used or the cement maturation before restoration. Biodentine can be used as a dentine substitute.

Citations

Citations to this article as recorded by  
  • Effect of Er Cr YSGG laser etching procedure on the bond strength of different calcium silicate cements
    Yesim Sesen Uslu, Hakan Yasin Gönder, Pinar Sesen, Gizem Gunduz Bektaş
    Lasers in Dental Science.2024;[Epub]     CrossRef
  • Managing Cracked Teeth with Root Extension: A Prospective Preliminary Study Using Biodentine™ Material
    Kênia Maria Soares de Toubes, Isabella Sousa Corrêa, Regina Célia Lopes Valadares, Stephanie Quadros Tonelli, Fábio Fernandes Borém Bruzinga, Frank Ferreira Silveira, Dr Karthikeyan Ramalingam
    International Journal of Dentistry.2024;[Epub]     CrossRef
  • In Vitro Resistance of Natural Molars vs. Additive-Manufactured Simulators Treated with Pulpotomy and Endocrown
    Marie-Laure Munoz-Sanchez, Alexis Gravier, Olivier Francois, Emmanuel Nicolas, Martine Hennequin, Nicolas Decerle
    Journal of Functional Biomaterials.2023; 14(9): 444.     CrossRef
  • Characterisation of the calcium silicate‐based cement–composite interface and the bonding strength with total‐etch or single/two‐stage self‐etch adhesive systems
    Abidin Talha Mutluay, Merve Mutluay
    Australian Endodontic Journal.2022; 48(3): 501.     CrossRef
  • Bond Strength of Adhesive Systems to Calcium Silicate-Based Materials: A Systematic Review and Meta-Analysis of In Vitro Studies
    Louis Hardan, Davide Mancino, Rim Bourgi, Alejandra Alvarado-Orozco, Laura Emma Rodríguez-Vilchis, Abigailt Flores-Ledesma, Carlos Enrique Cuevas-Suárez, Monika Lukomska-Szymanska, Ammar Eid, Maya-Line Danhache, Maryline Minoux, Youssef Haïkel, Naji Kharo
    Gels.2022; 8(5): 311.     CrossRef
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Review Article
Calcium silicate-based root canal sealers: a literature review
Miyoung Lim, Chanyong Jung, Dong-Hoon Shin, Yong-bum Cho, Minju Song
Restor Dent Endod 2020;45(3):e35.   Published online June 9, 2020
DOI: https://doi.org/10.5395/rde.2020.45.e35
AbstractAbstract PDFPubReaderePub

Epoxy resin-based sealers are currently widely used, and several studies have considered AH Plus to be the gold-standard sealer. However, it still has limitations, including possible mutagenicity, cytotoxicity, inflammatory response, and hydrophobicity. Drawing upon the advantages of mineral trioxide aggregate, calcium silicate-based sealers were introduced with high levels of biocompatibility and hydrophilicity. Because of the hydrophilic environment in root canals, water resorption and solubility of root canal sealers are important factors contributing to their stability. Sealers displaying lower microleakage and stronger push-out bond strength are also needed to endure the dynamic tooth environment. Although the physical properties of calcium silicate-based sealers meet International Organization for Standardization recommendations, and they have consistently reported to be biocompatible, they have not overcome conventional resin-based sealers in actual practice. Therefore, further studies aiming to improve the physical properties of calcium silicate-based sealers are needed.

Citations

Citations to this article as recorded by  
  • Effect of Different Tapered Gutta-Percha Points on Push-Out Bond Strength of Two Root Canal Sealers
    Warattama Suksaphar, Pakit Tungsawat, Ninnita Wongwatanasanti, Siripat Lertnantapanya, Prattana Yodmanothum
    European Journal of General Dentistry.2025;[Epub]     CrossRef
  • Effect of Electrical Heat Carrier Temperature on Bacterial Leakage of Endodontically Treated Teeth Using a Bioceramic Sealer
    Mir Ahmad Nabavi, Mahmood Reza Kalantar Motamedi, Pedram Fattahi, Saber Khazaei
    Clinical and Experimental Dental Research.2025;[Epub]     CrossRef
  • Nanoparticles modified bioceramic sealers on solubility, antimicrobial efficacy, pushout bond strength and marginal adaptation at apical-third of canal dentin
    Basil Almutairi, Fahad Alkhudhairy
    PeerJ.2025; 13: e18840.     CrossRef
  • Management of rarely seen internal tunnelling root resorption associated with a maxillary permanent incisor
    Kirsty A. Carney, Thibault N. E. Colloc, Julie K. Kilgariff
    British Dental Journal.2024; 236(12): 955.     CrossRef
  • Top tips for treatment planning: tooth-by-tooth prognosis - Part 3: endodontic prognosis
    Prashanti Eachempati, Andrew Harris, Guy Lambourn, Tony Francis, Ewen McColl
    British Dental Journal.2024; 237(9): 686.     CrossRef
  • Retreatability of calcium silicate-based sealers based on micro-computed tomographic evaluation − A systematic review
    Sundus Mohammed Bukhary
    The Saudi Dental Journal.2024; 36(10): 1278.     CrossRef
  • Evaluation of Setting Time, Flowability, Film Thickness, and Radiopacity of Experimental Monocalcium Silicate‐Based Root Canal Sealers
    Sukanya Juntha, Pakit Tungsawat, Ninnita Wongwatanasanti, Warattama Suksaphar, Siripat Lertnantapanya, Carlos M. Ardila
    International Journal of Dentistry.2024;[Epub]     CrossRef
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Research Articles
A micro-computed tomographic evaluation of root canal filling with a single gutta-percha cone and calcium silicate sealer
Jong Cheon Kim, Maung Maung Kyaw Moe, Sung Kyo Kim
Restor Dent Endod 2020;45(2):e18.   Published online February 12, 2020
DOI: https://doi.org/10.5395/rde.2020.45.e18
AbstractAbstract PDFPubReaderePub
Objectives

The purpose of this study was to evaluate the void of root canal filling over time when a calcium silicate sealer was used in the single gutta-percha cone technique.

Materials and Methods

Twenty-four J-shaped simulated root canals and twenty-four palatal root canals from extracted human maxillary molars were instrumented with ProFile Ni-Ti rotary instruments up to size 35/0.06 or size 40/0.06, respectively. Half of the canals were filled with Endoseal MTA and the other half were with AH Plus Jet using the single gutta-percha cone technique. Immediately after and 4 weeks after the root canal filling, the samples were scanned using micro-computed tomography at a resolution of 12.8 μm. The scanned images were reconstructed using the NRecon software and the void percentages were calculated using the CTan software, and statistically analyzed by 1-way analysis of variance, paired t-test and Tukey post hoc test.

Results

After 4 weeks, there were no significant changes in the void percentages at all levels in both material groups (p > 0.05), except at the apical level of the AH Plus Jet group (p < 0.05) in the simulated root canal showing more void percentage compared to other groups. Immediately after filling the extracted human root canals, the Endoseal MTA group showed significantly less void percentage compared to the AH Plus Jet group (p < 0.05).

Conclusions

Under the limitations of this study, the Endoseal MTA does not seem to reduce the voids over time.

Citations

Citations to this article as recorded by  
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    Maryam Gharechahi, Melika Hoseinzadeh, Saeed Moradi, Mina Mehrjouei
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    Chuta Kooanantkul, Richard M Shelton, Josette Camilleri
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    N. Linas, M.-L. Munoz-Sanchez, N. Decerle, P.-Y. Cousson
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    Amre R. Atmeh, Rakan Alharbi, Ibrahim Aljamaan, Abdulrahman Alahmari, Ashwin C. Shetty, Ahmed Jamleh, Imran Farooq
    Tomography.2022; 8(2): 778.     CrossRef
  • Clinical Efficacy of Sealer-based Obturation Using Calcium Silicate Sealers: A Randomized Clinical Trial
    Ji-hyung Kim, Sin-Yeon Cho, Yoonwoo Choi, Do-hyun Kim, Su-Jung Shin, Il-Young Jung
    Journal of Endodontics.2022; 48(2): 144.     CrossRef
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    Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
    International Endodontic Journal.2022; 55(S2): 384.     CrossRef
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    Mario Dioguardi, Cristian Quarta, Diego Sovereto, Giuseppe Troiano, Khrystyna Zhurakivska, Maria Bizzoca, Lorenzo Lo Muzio, Lucio Lo Russo
    Oral.2021; 1(1): 23.     CrossRef
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    Viresh Chopra, Graham Davis, Aylin Baysan
    Materials.2021; 15(1): 229.     CrossRef
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    Mehrsima Ghavami-Lahiji, Reza Tayefeh Davalloo, Gelareh Tajziehchi, Paria Shams
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    Su-Yeon Ko, Hae Won Choi, E-Deun Jeong, Vinicius Rosa, Yun-Chan Hwang, Mi-Kyung Yu, Kyung-San Min
    Materials.2020; 13(19): 4389.     CrossRef
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A micro-computed tomography evaluation of voids using calcium silicate-based materials in teeth with simulated internal root resorption
Vildan Tek, Sevinç Aktemur Türker
Restor Dent Endod 2020;45(1):e5.   Published online November 29, 2019
DOI: https://doi.org/10.5395/rde.2020.45.e5
AbstractAbstract PDFPubReaderePub
Objectives

The obturation quality of MTA, Biodentine, Total Fill BC root canal sealer (RCS), and warm gutta-percha (WGP) in teeth with simulated internal root resorption (IRR) was evaluated by using micro-computed tomography.

Materials and Methods

Standardized IRR cavities were created using 40 extracted maxillary central incisor teeth and randomly assigned into 4 groups (n = 10). IRR cavities were filled with MTA, Biodentine, Total Fill BC RCS (bulk-fill form) and WGP + Total Fill BC RCS. Percentage of voids between resorptive cavity walls and obturation material (external void), and inside the filling materials (internal voids) were measured.

Results

Total Fill BC sealer in the bulk-fill form presented significantly highest values of external and internal void percentages (p < 0.05). Biodentine showed a significantly lowest external void percentage (p < 0.05). WGP + Total Fill BC RCS presented significantly lower values of internal void percentages than all groups (p < 0.05), except Biodentine (p > 0.05).

Conclusion

None of the filling materials were created void-free obturation in resorption cavities. Biodentine may favor its application in teeth with IRR over Angelus MTA and bulk-fill form of Total Fill BC.

Citations

Citations to this article as recorded by  
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    Ammar M. Sharki, Ahmed H. Ali
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    Asel Usdat Ozturk, Ekin Dogan, Venus Seyedoskuyi, Berk Senguler, Asli Topaloglu-Ak
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    S Küçükkaya Eren
    Australian Dental Journal.2023;[Epub]     CrossRef
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    Hattan Mohammed Omar Baismail, Mohammed Ghazi Moiser Albalawi, Alaa Mofareh Thoilek Alanazi, Muhannad Atallah Saleem Alatawi, Badr Soliman Alhussain
    Annals of Dental Specialty.2021; 9(1): 87.     CrossRef
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  • 7 Crossref
Close layer
Coronal tooth discoloration induced by regenerative endodontic treatment using different scaffolds and intracanal coronal barriers: a 6-month ex vivo study
Noushin Shokouhinejad, Hassan Razmi, Maryam Farbod, Marzieh Alikhasi, Josette Camilleri
Restor Dent Endod 2019;44(3):e25.   Published online July 16, 2019
DOI: https://doi.org/10.5395/rde.2019.44.e25
AbstractAbstract PDFPubReaderePub
Objective

The aim of this study was to evaluate discoloration of teeth undergoing regenerative endodontic procedures (REPs) using blood clot or platelet-rich fibrin (PRF) as the scaffolds and different calcium silicate-based materials as the intracanal coronal barriers in an ex vivo model.

Materials and Methods

Forty-eight bovine incisors were prepared and disinfected using 1 mg/mL double antibiotic paste (DAP). The specimens were then randomly divided into 2 groups (n = 24) according to the scaffolds (blood or PRF). After placement of scaffolds each group was divided into 2 subgroups (n = 12) according to the intracanal coronal barriers (ProRoot MTA or Biodentine). The pulp chamber walls were sealed with dentin bonding agent before placement of DAP and before placement of scaffolds. The color changes (∆E) were measured at different steps. The data were analyzed using 2-way analysis of variance.

Results

Coronal discoloration induced by DAP was not clinically perceptible (ΔE ≤ 3.3). Regarding the type of the scaffold, coronal discoloration was significantly higher in blood groups compared with PRF groups at the end of REP and after 1 month (p < 0.05). However, no significant difference was found between PRF and blood clot after 6 months (p > 0.05). Considering the type of intracanal coronal barrier, no significant difference existed between ProRoot MTA and Biodentine (p > 0.05).

Conclusions

With sealing the dentinal tubules of pulp chamber with a dentin bonding agent and application of DAP as an intracanal medicament, coronal color change of the teeth following the use of PRF and blood sealed with either ProRoot MTA or Biodentine was not different at 6-month follow-up.

Citations

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    Luana Raphael da SILVA, Jader Camilo PINTO, Juliane Maria GUERREIRO-TANOMARU, Mário TANOMARU-FILHO
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Close layer
Effects of the exposure site on histological pulpal responses after direct capping with 2 calcium-silicate based cements in a rat model
Panruethai Trongkij, Supachai Sutimuntanakul, Puangwan Lapthanasupkul, Chitpol Chaimanakarn, Rebecca Wong, Danuchit Banomyong
Restor Dent Endod 2018;43(4):e36.   Published online August 22, 2018
DOI: https://doi.org/10.5395/rde.2018.43.e36
AbstractAbstract PDFPubReaderePub
Objectives

Direct pulp capping is a treatment for mechanically exposed pulp in which a biocompatible capping material is used to preserve pulpal vitality. Biocompatibility tests in animal studies have used a variety of experimental protocols, particularly with regard to the exposure site. In this study, pulp exposure on the occlusal and mesial surfaces of molar teeth was investigated in a rat model.

Materials and Methods

A total of 58 maxillary first molars of Wistar rats were used. Forty molars were mechanically exposed and randomly assigned according to 3 factors: 1) the exposure site (occlusal or mesial), 2) the pulp-capping material (ProRoot White MTA or Bio-MA), and 3) 2 follow-up periods (1 day or 7 days) (n = 5 each). The pulp of 6 intact molars served as negative controls. The pulp of 12 molars was exposed without a capping material (n = 3 per exposure site for each period) and served as positive controls. Inflammatory cell infiltration and reparative dentin formation were histologically evaluated at 1 and 7 days using grading scores.

Results

At 1 day, localized mild inflammation was detected in most teeth in all experimental groups. At 7 days, continuous/discontinuous calcified bridges were formed at exposure sites with no or few inflammatory cells. No significant differences in pulpal response according to the exposure site or calcium-silicate cement were observed.

Conclusions

The location of the exposure site had no effect on rat pulpal healing. However, mesial exposures could be performed easily, with more consistent results. The pulpal responses were not significantly different between the 2 capping materials.

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Close layer
Case Report
Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report
Cyril Villat, Brigitte Grosgogeat, Dominique Seux, Pierre Farge
Restor Dent Endod 2013;38(4):258-262.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.258
AbstractAbstract PDFPubReaderePub

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

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Review Article
Chemical characteristics of mineral trioxide aggregate and its hydration reaction
Seok-Woo Chang
Restor Dent Endod 2012;37(4):188-193.   Published online November 21, 2012
DOI: https://doi.org/10.5395/rde.2012.37.4.188
AbstractAbstract PDFPubReaderePub

Mineral trioxide aggregate (MTA) was developed in early 1990s and has been successfully used for root perforation repair, root end filling, and one-visit apexification. MTA is composed mainly of tricalcium silicate and dicalcium silicate. When MTA is hydrated, calcium silicate hydrate (CSH) and calcium hydroxide is formed. Formed calcium hydroxide interacts with the phosphate ion in body fluid and form amorphous calcium phosphate (ACP) which finally transforms into calcium deficient hydroxyapatite (CDHA). These mineral precipitate were reported to form the MTA-dentin interfacial layer which enhances the sealing ability of MTA. Clinically, the use of zinc oxide euginol (ZOE) based materials may retard the setting of MTA. Also, the use of acids or contact with excessive blood should be avoided before complete set of MTA, because these conditions could adversely affect the hydration reaction of MTA. Further studies on the chemical nature of MTA hydration reaction are needed.

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