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• Multifunctional Dental Composite with Piezoelectric Nanofillers for Combined Antibacterial and Mineralization Effects
  Carolina Montoya, Anubhav Jain, Juan José Londoño, Santiago Correa, Peter I. Lelkes, Mary Anne Melo, Santiago Orrego
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• Publication patterns in Restorative Dentistry and Endodontics
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• Expert consensus on intentional tooth replantation
  Zhengmei Lin, Dingming Huang, Shuheng Huang, Zhi Chen, Qing Yu, Benxiang Hou, Lihong Qiu, Wenxia Chen, Jiyao Li, Xiaoyan Wang, Zhengwei Huang, Jinhua Yu, Jin Zhao, Yihuai Pan, Shuang Pan, Deqin Yang, Weidong Niu, Qi Zhang, Shuli Deng, Jingzhi Ma, Xiuping
  International Journal of Oral Science.2025;[Epub]     CrossRef
• Outcome of intentional replantation of endodontically treated teeth with periapical pathosis: A systematic review and meta‐analysis
  Faizan Javed, Kamil Zafar, Farhan R. Khan
  Australian Endodontic Journal.2023; 49(S1): 494.     CrossRef
• Proximity of maxillary molar apexes to the cortical bone surface and the maxillary sinus
  Han Shin Lee, Dokyung Kim, Sung Kyo Kim
  Restorative Dentistry & Endodontics.2022;[Epub]     CrossRef
• Alveolar bone thickness overlying healthy maxillary and mandibular teeth: A systematic review and meta-analysis
  Marziyeh Shafizadeh, Azita Tehranchi, Armin Shirvani, Saeed Reza Motamedian
  International Orthodontics.2021; 19(3): 389.     CrossRef
• Relationship between the anatomic structures and mandibular posterior teeth for endodontic surgery in a Turkish population: a cone-beam computed tomographic analysis
  Zeliha Uğur Aydın, Duygu Göller Bulut
  Clinical Oral Investigations.2019; 23(9): 3637.     CrossRef

Exposing sound structure of a subgingivally fractured tooth using orthodontic extrusion is considered to be a conservative way to re-establish biologic width without sacrificing esthetics or jeopardizing periodontal support of neighboring teeth. When a misaligned tooth is traumatically involved, a more comprehensive approach combining tooth extrusion and re-alignment may be necessary for a successful restorative outcome. This case report describes a successful esthetic management of a patient with complicated crown-root fracture on the maxillary right central incisor and pre-existing malocclusion in the maxillary anterior region. Forced eruption along with re-alignment of teeth by orthodontic movement seems to allow re-positioning of the fracture line to a favorable position and correction of crowding, providing a better esthetic result.

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• Effects of systematic bisphosphonate use in patients under orthodontic treatment: a systematic review
  Vasileios F Zymperdikas, Maria P Yavropoulou, Eleftherios G Kaklamanos, Moschos A Papadopoulos
  European Journal of Orthodontics.2020; 42(1): 60.     CrossRef
• In vitro retention efficiency of temporary type zinc oxide cement for orthodontic forced eruption
  Renato Nieto-Aguilar, Deyanira Serrato-Ochoa, Rafael Medina-Navarro, Asdrúbal Aguilera-Méndez, Karina Denisse Morales-Soto, Juan Pablo Loyola-Rodriguez, Antonio Campos, Miguel Alaminos
  International Orthodontics.2019; 17(1): 96.     CrossRef

Maxillary lateral incisors usually exhibit a single root with a single canal. However, maxillary lateral incisor teeth with unusual morphology of root canal system are frequently reported. These cases of variable root canal anatomy can be treated well by nonsurgical endodontic methods. A detailed description of root canal morphology is fundamental for successful endodontic treatment. Treatment using an operating microscope, radiographs from different angles, and cone-beam computerized tomography (CBCT) can produce more predictable endodontic outcomes.

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• Endodnontic Management of a Maxillary Lateral Incisor with Two Roots
  Pujan Kranti Kayastha, Merina Shakya, Laxman Poudel
  Journal of Interdisciplinary Dentistry.2022; 12(1): 32.     CrossRef
• Non-surgical management of dens invaginatus type IIIB in maxillary lateral incisor with three root canals and 6-year follow-up: A case report and review of literature
  Suraj Arora, Gurdeep Singh Gill, Shahabe Abullais Saquib, Priyanka Saluja, Suheel M Baba, Shafait Ullah Khateeb, Anshad M Abdulla, Shashit Shetty Bavabeedu, Ahmed Babiker Mohamed Ali, Mohamed Fadul A Elagib
  World Journal of Clinical Cases.2022; 10(33): 12240.     CrossRef
• Endodontic management and follow-up of two rooted maxillary lateral incisor with open apex – A case report
  R AnithaKumari, Sneha Jeetendra, Siddharth Rai, Sudhanva Eregowda
  IP Indian Journal of Conservative and Endodontics.2020; 5(4): 200.     CrossRef
• Geminated Maxillary Lateral Incisor with Two Root Canals
  Nayara Romano, Luis Eduardo Souza-Flamini, Isabela Lima Mendonça, Ricardo Gariba Silva, Antonio Miranda Cruz-Filho
  Case Reports in Dentistry.2016; 2016: 1.     CrossRef
• Surgical management with intentional replantation on a tooth with palato-radicular groove
  Jorge Forero-López, Luis Gamboa-Martínez, Laura Pico-Porras, Javier Laureano Niño-Barrera
  Restorative Dentistry & Endodontics.2015; 40(2): 166.     CrossRef
• Use of cone-beam computed tomography and three-dimensional modeling for assessment of anomalous pulp canal configuration: a case report
  Alper Sinanoglu, Dilek Helvacioglu-Yigit, Ibrahim Mutlu
  Restorative Dentistry & Endodontics.2015; 40(2): 161.     CrossRef
• Endodontic management of a mandibular second molar with radix entomolaris: a case report
  Rosaline Hannah, Deivanayagam Kandaswamy, Nachimuthu Jayaprakash
  Restorative Dentistry & Endodontics.2014; 39(2): 132.     CrossRef

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• Effect of Herbal Antioxidant on Push-out Bond Strength of Resin-based Composite to Dentin after Intracoronal Bleaching: An In Vitro Study
  Parinitha MS, Akshay G, Vidya G. Doddawad, Ashwini Tumkur Shivakumar, Sowmya Halasabalu Kalgeri
  Journal of Pharmacology and Pharmacotherapeutics.2024;[Epub]     CrossRef
• Photon-Induced Photoacoustic Streaming Activation of the Postbleaching Antioxidant Application Rapidly Improves Bonding to Pulp Chamber Dentin
  Nasibe Aycan Yilmaz, Hicran Dönmez Özkan
  Photobiomodulation, Photomedicine, and Laser Surgery.2021; 39(4): 289.     CrossRef
• Hypericum perforatum L.: A Potent Antioxidant Source for the Treatment of Oxidized Dentin: An Experimental In Vitro Study
  Nasibe Aycan Yilmaz, Rukiye Yavaser, Arife Alev Karagozler
  Journal of Advanced Oral Research.2021; 12(1): 57.     CrossRef
• Influence of a short‐time antioxidant application on the dentin bond strength after intracoronal bleaching
  Muhammet Karadas, Sezer Demirbuga
  Microscopy Research and Technique.2019; 82(10): 1720.     CrossRef
• Composite resin shear bond strength on bleached dentin increased by 35% sodium ascorbate application
  Tunjung Nugraheni, N Nuryono, Siti Sunarintyas, Ema Mulyawati
  Dental Journal (Majalah Kedokteran Gigi).2017; 50(4): 178.     CrossRef
• Antioxidant therapy enhances pulpal healing in bleached teeth
  Adriano Fonseca Lima, Marcelo Rocha Marques, Diana Gabriela Soares, Josimeri Hebling, Giselle Maria Marchi, Carlos Alberto de Souza Costa
  Restorative Dentistry & Endodontics.2016; 41(1): 44.     CrossRef
• Influence of Ethanol Pretreatment on the Bonding of Resin Composite to Bleached Dentin
  Ga-Eun Son, Tae-Yub Kwon, Young Kyung Kim
  Korean Journal of Dental Materials.2015; 42(4): 279.     CrossRef
• Effect of 35% Sodium Ascorbate Treatment on Microtensile Bond Strength after Nonvital Bleaching
  Jason R. Hansen, Kenneth J. Frick, Mary P. Walker
  Journal of Endodontics.2014; 40(10): 1668.     CrossRef
• Pull-out bond strength of a self-adhesive resin cement to NaOCl-treated root dentin: effect of antioxidizing agents
  Maryam Khoroushi, Marzieh Kachuei
  Restorative Dentistry & Endodontics.2014; 39(2): 95.     CrossRef

Closure of interdental spaces using proximal build-ups with resin composite is considered to be practical and conservative. However, a comprehensive approach combining two or more treatment modalities may be needed to improve esthetics. This case report describes the management of a patient with multiple diastemas, a peg-shaped lateral incisor and midline deviation in the maxillary anterior area. Direct resin bonding along with orthodontic movement of teeth allows space closure and midline correction, consequently, creating a better esthetic result.

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• Gingival Conditioning with Provisional Composite Veneer Prior to Final Dental Restoration: Three-year Follow-up
  B Mueller, GB Rauber, LA Linhares, JK Bernardon, E Santini, LF Pottmaier
  Operative Dentistry.2023; 48(3): 237.     CrossRef
• Effectiveness, longevity, and color stability of in-office bleaching (6% H2O2 gel/Violet LED) and diastema closure with direct composite: 3-year follow-up
  Ikejiri Larissa Luri Almeida Amorim, Álamo Larissa , Galli Mateus Zamora , Bombonatti Juliana Fraga Soares , de Amoêdo Campos Velo Marilia Mattar , Mondelli Rafael Francisco Lia
  Journal of Clinical Advances in Dentistry.2023; 7(1): 001.     CrossRef
• Ortodontik Tedavi Bitiminden Sonra Polidiastemanın Kompozit Rezin Ile Rehabilitasyonu: Olgu Sunumu
  Rümeysa BATTAL, Hacer Deniz ARISU
  Selcuk Dental Journal.2022; 9(4): 127.     CrossRef
• Multidisciplinary Approach to Treatment of Midline Diastema With Edge-to-Edge Bite
  Sumukh Nerurkar, Ranjit Kamble, Japneet Kaiser, Jeni Mathew
  Cureus.2022;[Epub]     CrossRef
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  Abdulkadir HARMANKAYA, Hakan Yasin GÖNDER
  Selcuk Dental Journal.2022; 9(4): 86.     CrossRef
• ANTERİOR DİASTEMALARIN DİREKT KOMPOZİT REZİN RESTORASYONLARLA ESTETİK REHABİLİTASYONU: 5 OLGU SUNUMU
  Handan YILDIRIM, Esra ÖZYURT
  Selcuk Dental Journal.2020; 7(2): 334.     CrossRef
• VAKUMLA ŞEKİLLENDİRİLEN ORTODONTİK PEKİŞTİRME APAREYLERİNİN KOMPOZİT RESTORASYONLARIN KLİNİK BAŞARISINA ETKİSİ
  Serdar AKARSU, Sultan AKTUĞ KARADEMİR, Süleyman Kutalmış BÜYÜK
  Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2020; : 1.     CrossRef
• Aesthetic Smile Coming with Direct Composite Resin Laminate Restorations: Two Case Reports
  Funda Demir, Elif Aybala Oktay, Numan Aydın, Fulya Toksoy Topçu, Ertürk Bilgeç
  Ankara Medical Journal.2018;[Epub]     CrossRef
• Effects of Different Demineralization‐Inhibiting Methods on the Shear Bond Strength of Glass‐Ceramics
  Erhan Dilber, Mehmet Akın, Tevfik Yavuz, Ali Erdem
  Journal of Prosthodontics.2015; 24(5): 407.     CrossRef
• Correction of Mandibular Prognathism in Combination with Polydiastema Using Rectangular Body Ostectomy: Literature Review and Case Report
  Metin Sencimen, Abdullah Tugrul Coskun, Gurkan Rasit Bayar, Handan Altug, Hasan Ayberk Altug, Tamer Zerener
  Case Reports in Clinical Medicine.2014; 03(11): 601.     CrossRef
• Predictable interproximal tissue removal with a surgical stent
  Fausto Frizzera, Suzane Cristina Pigossi, Mateus Rodrigues Tonetto, William Kabbach, Elcio Marcantonio
  The Journal of Prosthetic Dentistry.2014; 112(4): 727.     CrossRef

The objective of this article was to present two nonodontogenic conditions that may mimic odontogenic toothache: trigeminal neuralgia and burning mouth syndrome. Two cases are presented in which one is related to the upper left second premolar and the other is related to the upper left first molar. Both showed pain when chewing. These two cases highlight the complexities involved in diagnosing nonodontogenic toothache. This article demonstrates the importance of having a thorough knowledge of both odontogenic and nonodontogenic toothache, as well as the need for careful evaluation of the nature of the pain and history, clinical and radiographic examinations.

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• Analysis of Final Diagnosis of Patients with Suspected Nonodontogenic Toothache: A Retrospective Study
  Jeong Yeop Chun, Young Joo Shim
  Journal of Oral Medicine and Pain.2024; 49(3): 57.     CrossRef
• Interactions of Acetyl-11-Keto-Beta-Boswellic Acid on Catechol-O-Methyltransferase in the Management of Masticatory Myofascial Pain Syndrome
  Ramya Suresh, Pradeep Kumar Yadalam, Ramya Ramadoss, Karthikeyan Ramalingam, Arvind Muthukrishnan
  Cureus.2024;[Epub]     CrossRef
• Assessment of Concordance between Chairside Ultrasonography and Digital Palpation in Detecting Myofascial Trigger Points in Masticatory Myofascial Pain Syndrome
  Mohamed Elbarbary, Michael Goldberg, Howard C. Tenenbaum, David K. Lam, Bruce V. Freeman, David J. Pustaka, David Mock, Joseph Beyene, Amir Azarpazhooh
  Journal of Endodontics.2023; 49(2): 129.     CrossRef
• Masticatory Myofascial Pain Syndrome: Implications for Endodontists
  Mohamed Elbarbary, Ariel Oren, Michael Goldberg, Bruce V. Freeman, David Mock, Howard C. Tenenbaum, Amir Azarpazhooh
  Journal of Endodontics.2022; 48(1): 55.     CrossRef
• PRICE 2020 guidelines for reporting case reports in Endodontics: explanation and elaboration
  V. Nagendrababu, B. S. Chong, P. McCabe, P. K. Shah, E. Priya, J. Jayaraman, S. J. Pulikkotil, P. M. H. Dummer
  International Endodontic Journal.2020; 53(7): 922.     CrossRef
• Clinical Outline of Oral Diseases
  Arvind Babu Rajendra Santosh, Doryck Boyd, Kumaraswamy Kikeri Laxminarayana
  Dental Clinics of North America.2020; 64(1): 1.     CrossRef
• Nonodontogenic Sources of Dental Pain
  Scott E. Schames, Michael Jordan, Hila Robbins, Lenard Katz, Kaitlyn Tarbert
  Journal of the California Dental Association.2016; 44(8): 507.     CrossRef
• Nonodontogenic toothaches
  Edward F. Wright
  The Journal of the American Dental Association.2015; 146(6): 406.     CrossRef
• Síndrome de boca ardiente: claves diagnósticas y terapéuticas
  Eduardo Chimenos-Küstner, Cristina Arcos-Guerra, Maria Sueli Marques-Soares
  Medicina Clínica.2014; 142(8): 370.     CrossRef

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• Influence of different kinematics on stationary and dynamic torsional behavior of JIZAI nickel-titanium rotary instruments: An in vitro study
  Myint Thu, Arata Ebihara, Moe Sandar Kyaw, Satoshi Omori, Keiichiro Maki, Shunsuke Kimura, Hayate Unno, Takashi Okiji
  Journal of Dental Sciences.2023; 18(3): 1170.     CrossRef
• Analysis of Torque and Force Induced by Rotary Nickel-Titanium Instruments during Root Canal Preparation: A Systematic Review
  Myint Thu, Arata Ebihara, Sherif Adel, Takashi Okiji
  Applied Sciences.2021; 11(7): 3079.     CrossRef
• Mechanical and geometric features of endodontic instruments and its clinical effect
  Hyeon-Cheol Kim
  Journal of Korean Academy of Conservative Dentistry.2011; 36(1): 1.     CrossRef

Screw-in effect is one of the unintended phenomena that occurs during the root canal preparation with nickel-titanium rotary files. The aim of this study was to compare the screw-in effect among various nickel-titanium rotary file systems.

Six different nickel-titanium rotary instruments (ISO 20/.06 taper) were used: K3™ (SybronEndo, Glendora, CA, USA), M_two (VDW GmbH, München, Germany), NRT with safe-tip and with active tip (Mani Inc., Shioya-gun, Japan), ProFile® (Dentsply-Maillefer, Ballaigues, Switzerland) and ProTaper® (Dentsply-Maillefer, Ballaigues, Switzerland). For ProTaper®, S2 was selected because it has size 20. Root canal instrumentations were done in sixty simulated single-curved resin root canals with a rotational speed of 300 rpm and single pecking motion. A special device was designed to measure the force of screw-in effect. A dynamometer of the device recorded the screw-in force during simulated canal preparation and the recorded data was stored in a computer with designed software (LCV-USE-VS, Lorenz Messtechnik GmbH, Alfdorf, Germany). The data were subjected to one-way ANOVA and Tukey's multiple range test for post-hoc test. P value of less than 0.05 was regarded significant.

ProTaper® produced significantly more screw-in effects than any other instruments in the study (p < 0.001). K3™ produced significantly more screw-in effects than M_two, and ProFile® (p < 0.001). There was no significant difference among M_two, NRT, and ProFile® (p > 0.05), and between NRT with active tip and NRT with safe one neither (p > 0.05).

From the result of the present study, it was concluded, therefore, that there seems significant differences of screw-in effect among the tested nickel-titanium rotary instruments. The radial lands and rake angle of nickel-titanium rotary instrument might be the cause of the difference.

Citations

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• Impact of Radial Lands on the Reduction of Torque/Force Generation of a Heat-Treated Nickel-Titanium Rotary Instrument
  Taro Nakatsukasa, Arata Ebihara, Moe Sandar Kyaw, Satoshi Omori, Hayate Unno, Shunsuke Kimura, Keiichiro Maki, Takashi Okiji
  Applied Sciences.2022; 12(5): 2620.     CrossRef
• Comparative evaluation of mechanical properties and shaping performance of heat-treated nickel titanium rotary instruments used in the single-length technique
  Taro NAKATSUKASA, Arata EBIHARA, Shunsuke KIMURA, Keiichiro MAKI, Miki NISHIJO, Daisuke TOKITA, Takashi OKIJI
  Dental Materials Journal.2021; 40(3): 743.     CrossRef
• Analysis of Torque and Force Induced by Rotary Nickel-Titanium Instruments during Root Canal Preparation: A Systematic Review
  Myint Thu, Arata Ebihara, Sherif Adel, Takashi Okiji
  Applied Sciences.2021; 11(7): 3079.     CrossRef
• Influence of rotational speed on torque/force generation and shaping ability during root canal instrumentation of extracted teeth with continuous rotation and optimum torque reverse motion
  M. S. Kyaw, A. Ebihara, Y. Kasuga, K. Maki, S. Kimura, P. H. Htun, T. Nakatsukasa, T. Okiji
  International Endodontic Journal.2021; 54(9): 1614.     CrossRef
• Influence of glide path on the screw-in effect and torque of nickel-titanium rotary files in simulated resin root canals
  Jung-Hong Ha, Sang-Shin Park
  Restorative Dentistry & Endodontics.2012; 37(4): 215.     CrossRef
• Influence of root canal curvature on the screw-in effect of nickel-titanium rotary files in simulated resin root canal
  Ji-Young Son, Jung-Hong Ha, Young-Kyung Kim
  Journal of Korean Academy of Conservative Dentistry.2010; 35(5): 374.     CrossRef
• Influence of taper on the screw-in effect of nickel-titanium rotary files in simulated resin root canal
  Hye-Jin Sung, Jung-Hong Ha, Sung-Kyo Kim
  Journal of Korean Academy of Conservative Dentistry.2010; 35(5): 380.     CrossRef

Recently, self-etching adhesive system has been introduced to simplify the clinical bonding procedures. It is less acidic compared to the phosphoric acid, thus there is doubt whether this system has enough bond strength to enamel. The purpose of this study was to investigate the influence of additional etching on the adhesion of resin composite to enamel.

Ninety extracted bovine permanent anterior teeth were used. The labial surfaces of the crown were ground with 600-grit abrasive paper under wet condition. The teeth were randomly divided into six groups of 15 teeth each. Clearfil SE Bond®, Adper™ Prompt L-Pop and Tyrian SPE™ were used as self-etching primers. Each self-etching primers were applied in both enamel specimens with and without additional etching. For additional etching groups, enamel surface was pretreated with 32% phosphoric acid (UNI-ETCH, Bisco, Inc., Schaumburg, IL, USA). Hybrid resin composite Clearfil AP-X, (Kuraray Co., Ltd., Osaka, Japan) was packed into the mold and light-cured for 40 seconds. Twenty-four hours after storage, the specimens were tested in shear bond strength. The data for each group were subjected to independent t - test at p < 0.01 to make comparisons among the groups.

In Clearfil SE Bond®, shear bond strength of additional etching group was higher than no additional etching group (p < 0.01). In Adper™ Prompt L-Pop and Tyrian SPE, there were no significant difference between additional etching and non-etching groups (p > 0.01).

In conclusion, self-etching adhesive system with weak acid seems to have higher bond strength to enamel with additional etching, while self-etching adhesive system with strong acid seems not.

Citations

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• Microtensile bond strength of silorane-based composite specific adhesive system using different bonding strategies
  Laura Alves Bastos, Ana Beatriz Silva Sousa, Brahim Drubi-Filho, Fernanda de Carvalho Panzeri Pires-de-Souza, Lucas da Fonseca Roberti Garcia
  Restorative Dentistry & Endodontics.2015; 40(1): 23.     CrossRef

The purpose of this study was to evaluate the influence of the AH-26 root canal sealer on the shear bond strength of composite resin to dentin.

One hundred and forty four (144) extracted, sound human molars were used. After embedding in a cylindrical mold, the occlusal part of the anatomical crown was cut away and trimmed in order to create a flat dentin surface. The teeth were randomly divided into three groups; the AH-26 sealer was applied to the AH-26 group, and zinc-oxide eugenol (ZOE) paste was applied to the ZOE group. The dentin surface of the control group did not receive any sealer.

A mount jig was placed against the surface of the teeth and the One-step dentin bonding agent was applied after acid etching. Charisma composite resin was packed into the mold and light cured. After polymerization, the alignment tube and mold were removed and the specimens were placed in distilled water at 37℃ for twenty four hours. The shear bond strength was measured by an Instron testing machine. The data for each group were subjected to one-way ANOVA and Tukey's studentized rank test so as to make comparisons between the groups.

The AH-26 group and the control group showed significantly higher shear bond strength than the ZOE group (p < 0.05).

There were no significant differences between the AH-26 group and the control one (p > 0.05).

Under the conditions of this study, the AH-26 root canal sealer did not seem to affect the shear bond strength of the composite resin to dentin while the ZOE sealer did. Therefore, there may be no decrease in bond strength when the composite resin core is built up immediately after a canal filling with AH-26 as a root canal sealer.

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• Is Zinc Oxide Eugenol Cement Still Impeding the Use of Resin-based Restoration? A Systematic Review
  Fawaz Pullishery, Hajer Ayed Alhejoury, Mohammed Turkistani, Yasser Refay Souror
  Dentistry and Medical Research.2021; 9(2): 59.     CrossRef
• A comparative evaluation of removal of gutta percha using two retreatment file system: An in vitro study
  Shruthi Mary Sunil, Balakrishnan Rajkumar, Vishesh Gupta, Akanksha Bhatt, Pragyan Paliwal
  IP Indian Journal of Conservative and Endodontics.2020; 5(2): 53.     CrossRef
• Evaluation of softening ability of Xylene & Endosolv-R on three different epoxy resin based sealers within 1 to 2 minutes - anin vitrostudy
  Pratima Ramakrishna Shenoi, Gautam Pyarelal Badole, Rajiv Tarachand Khode
  Restorative Dentistry & Endodontics.2014; 39(1): 17.     CrossRef
• Influence of Sodium Ascorbate on Microtensile Bond Strengths to Pulp Chamber Dentin treated with NaOCl
  Soo-Yeon Jeon, Kwang-Won Lee, Mi-Kyung Yu
  Journal of Korean Academy of Conservative Dentistry.2008; 33(6): 545.     CrossRef

To evaluate the effect of vital tooth bleaching agent and alcohol pretreatment on dentin bonding, flat dentin windows were produced on the buccal side of the crowns of fifty-five extracted, human premolars. A bleaching gel, Opalescence® with 10% of carbamide peroxide (Ultradent Product, USA) was daily applied on the teeth of three experimental groups for six hours for 10 consecutive days, while teeth of a control group were not bleached. After 6 hours of bleaching gel application, the specimens were washed and stored in saline until the next day application. After application of One-step® dentin bonding agent (Bisco, USA), Z-250® resin (3M-ESPE, USA) was bonded to dentin with a mount jig. Shear bond strength was measured with an Instron machine (Type 4202, Instron Corp., USA) after 24 hours. The results were analyzed using one-way ANOVA and Duncan's multiple range test at p < 0.05.

Immediate bonding group showed significantly lower bond strength than un-bleached control group (p < 0.05).

Ethanol-treated group showed significantly higher bond strength compared to immediate bonding group (p < 0.05). However, the bond strength of the ethanol treatment group was lower than that of the un-bleached control group (p < 0.05).

There were no significant difference in shear bond strength between the 2-week delayed bonding group and the ethanol-treated group (p > 0.05) and between delayed bonding group and un-bleached control group (p > 0.05).

In the condition of the present study, it seems that alcohol pretreatment after bleaching procedure can reduce the adverse effect of vital bleaching agent on dentin bonding.

Citations

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• Effect of the bleaching light on whitening efficacy
  Jong-Hyun Park, Hye-Jin Shin, Deok-Young Park, Se-Hee Park, Jin-Woo Kim, Kyung-Mo Cho
  Journal of Korean Academy of Conservative Dentistry.2009; 34(2): 95.     CrossRef

The purpose of this study was to investigate the function of calcitonin gene-related peptide (CGRP) in regulatory mechanism of pulpal microcirculation with the aim of elucidating neurogenic inflammation.

Experiments were performed on twelve cats under general anesthesia. CGRP was administered through the femoral vein to see the systemic influence and through the external carotid artery to see the local effect. Sympathetic nerve to the dental pulp was stimulated electrically and pulpal blood flow (PBF) was measured with a laser Doppler flowmeter on the canine teeth to the drug administration. The paired variables of control and experimental data were compared by paired t-test and differences with p < 0.05 were considered statistically significant.

Systemic administration of CGRP (0.3 μg/kg) exerted decreases in systemic blood pressure and caused changes in PBF with an initial increase followed by decrease and a more marked second increase and decrease.

Close intra-arterial (i.a.) injection of CGRP (0.03 μ/kg) resulted in slight PBF increase. The effect of CGRP resulted in no significant increase in PBF in the presence of CGRP_8-37.

The electrical stimulation of the sympathetic nerve alone resulted in PBF decreases. The i.a. administration of CGRP following the electrical stimulation of the sympathetic nerve compensated the decreased PBF. Therefore, CGRP effectively blocked the sympathetic nerve stimulation-induced PBF decrease.

Results of the present study have provided evidences that even though the local vasodilatory function of CGRP are weak, CGRP is effectively involved in blocking the vasoconstriction caused by sympathetic nerve stimulation in the feline dental pulp.

The purpose of this study was to evaluate the influence of plugger penetration depth on the apical extrusion of root canal sealer during root canal obturation with Continuous Wave of Condensation Technique.

Root canals of forty extracted human teeth were divided into four groups and were prepared up to size 40 of 0.06 taper with ProFile. After drying, canals of three groups were filled with Continuous Wave of Condensation Technique with System B™ and different plugger penetration depths of 3, 5, and 7 mm from the apex. Canals of one group were filled with cold lateral compaction technique as a control. Canals were filled with non-standardized master gutta-percha cones and 0.02 mL of Sealapex. Apical extruded sealer was collected in a container and weighed. Data was analyzed with one-way ANOVA and Duncan’s Multiple Range Test. 3 and 5 mm penetration depth groups in Continuous Wave of Condensation Technique showed significantly more extrusion of root canal sealer than 7 mm penetration depth group (p < 0.05). However, there was no significant difference between 7 mm depth group in Continuous Wave of Condensation Technique and cold lateral compaction group (p < 0.05).

The result of this study demonstrates that deeper plugger penetration depth causes more extrusion of root canal sealer in root canal obturation by Continuous Wave of Condensation Technique. Therefore, special caution is needed when plugger penetration is deeper in the canal in Continuous Wave of Condensation Technique to minimize the amount of sealer extrusion beyond apex.

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• Influence of plugger penetration depth on the area of the canal space occupied by gutta-percha
  Young Mi Lee, Ho-young So, Young Kyung Kim, Sung Kyo Kim
  Journal of Korean Academy of Conservative Dentistry.2006; 31(1): 66.     CrossRef

The purpose of this study was to investigate the influence of NK1 receptor antagonists on the pulpal blood flow (PBF) when applied iontophoretically through the dentinal cavity of the teeth in order to understand whether iontophoretically applied NK1 receptor antagonists can control the pulpal inflammation.

Eleven cats were anesthetized with alpha-chloralose and urethane, and substance P (SP) was administered to the dental pulp through the catheterized lingual artery in doses that caused PBF change without the influence of systemic blood pressure. NK1 receptor antagonists were applied iontophoretically to the prepared dentinal cavity of ipsilateral canine teeth of the drug administration, and PBF was monitored. Data were analyzed statistically with paired t-test.

PBF increase after iontophoretic application of the NK1 receptor antagonists followed by the intra-arterial administration of SP was significantly less than PBF increase after iontophoretic application of the 0.9% saline followed by the intra-arterial administration of SP as a control (p < 0.05).

Iontophoretic application of the NK1 receptor antagonists (0.2~3.4 mM) following the intra-arterial administration of SP resulted in less increase of PBF than the iontophoretic application of the 0.9% saline following the intra-arterial administration of SP as a control (p < 0.05).

Therefore, the results of the present study provide evidences that the iontophoretic application is an effective method to deliver drugs to the dental pulp, and that iontophoretically applied NK1 receptor antagonists block SP-induced vasodilation effectively. The above results show the possibility that the iontophoretical application of NK1 receptor antagonists can control the neurogenic inflammation in the dental pulp.

Nitric oxide (NO) is a small molecule (mol. wt. 30 Da) and oxidative free radical. It is uncharged and can therefore diffuse freely within and between cells across membrane. Such characteristics make it a biologically important messenger in physiologic processes such as neurotransmission and the control of vascular tone. NO is also highly toxic and is known to acts as a mediator of cytotoxicity during host defense.

NO is synthesized by nitric oxide synthase (NOS) through L-arginine/nitric oxide pathway which is a dioxygenation process. NO synthesis involves several participants, three co-substrates, five electrons, five co-factors and two prosthetic groups.

Under normal condition, low levels of NO are synthesized by type I and III NOS for a short period of time and mediates many physiologic processes. Under condition of oxidant stress, high levels of NO are synthesized by type II NOS and inhibits a variety of metabolic processes and can also cause direct damage to DNA. Such interaction result in cytostasis, energy depletion and ultimately cell death. NO has the potential to interact with a variety of intercellular targets producing diverse array of metabolic effects.

It is known that NO is involved in hemodynamic regulation, neurogenic inflammation, re-innervation, management of dentin hypersensitivity on teeth. Under basal condition of pulpal blood flow, NO provides constant vasodilator tone acting against sympathetic vasoconstriction. Substance P, a well known vasodilator, was reported to be mediated partly by NO, while calcitonin-gene related peptide has provided no evidence of its relation with NO.

This review describes the roles of NO in dental pulp in addition to the known general roles of it.

Citations

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  Yeon Ju Oh, Jae Min Lee, Joon Hyung Yeo, Sung Soo Kim, Seung Geun Yeo
  Antioxidants.2025; 14(3): 327.     CrossRef
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