This systematic review and network meta-analysis aimed to answer the following focused research question: “Does the type of endodontic sealer affect the postoperative pain in patients who received endodontic treatment?” Different databases and grey literature were surveyed. Only one randomized controlled trial were included. The risk of bias in the studies was evaluated by using the Cochrane Collaboration’s tool. A random-effects meta-analysis was conducted to compare the risk and intensity of postoperative pain. The quality of the body of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation approach. Out of 11,601 studies, 15 remained for qualitative analyses and 12 for meta-analysis. Seven studies were classified at high risk of bias, and 8 studies raised some concerns. No significant differences between the endodontic materials were observed in the direct comparisons, both in risk and in intensity of postoperative pain (pairwise comparisons with 2 studies: I² = 0%; p > 0.05 and 8 studies: I² = 23%; p > 0.05, respectively). The certainty of the evidence was graded as low or moderate. There was no difference in the risk and intensity of postoperative pain after filling with different endodontic sealers. Further systematic reviews should be conducted.

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Magnetic resonance imaging (MRI) is an advanced diagnostic tool used in both medicine and dentistry. Since it functions based on a strong uniform static magnetic field and radiofrequency pulses, it is advantageous over imaging techniques that rely on ionizing radiation. Unfortunately, the magnetic field and radiofrequency pulses generated within the magnetic resonance imager interact unfavorably with dental materials that have magnetic properties. This leads to unwanted effects such as artifact formation, heat generation, and mechanical displacement. These are a potential source of damage to the oral tissue surrounding the affected dental materials. This review aims to compile, based on the current available evidence, recommendations for dentists and radiologists regarding the safety and appropriate management of dental materials during MRI in patients with orthodontic appliances, maxillofacial prostheses, dental implants, direct and indirect restorative materials, and endodontic materials.

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  Journal of Microbiota.2024;[Epub]     CrossRef
• Physicochemical Properties, Cytocompatibility, and Biocompatibility of a Bioactive Glass Based Retrograde Filling Material
  Kazumasa Murata, Ayako Washio, Takahiko Morotomi, Thira Rojasawasthien, Shoichiro Kokabu, Chiaki Kitamura
  Nanomaterials.2021; 11(7): 1828.     CrossRef
• Cell migration and osteo/odontogenesis stimulation of iRoot FS as a potential apical barrier material in apexification
  Y. Liu, X. M. Liu, J. Bi, S. Yu, N. Yang, B. Song, X. Chen
  International Endodontic Journal.2020; 53(4): 467.     CrossRef
• Biocompatibility of Biodentine™ ® with Periodontal Ligament Stem Cells: In Vitro Study
  Duaa Abuarqoub, Nazneen Aslam, Hanan Jafar, Zakariya Abu Harfil, Abdalla Awidi
  Dentistry Journal.2020; 8(1): 17.     CrossRef
• A micro-computed tomographic study of remaining filling materials of two bioceramic sealers and epoxy resin sealer after retreatment
  KyungJae Kim, Da Vin Kim, Sin-Young Kim, SungEun Yang
  Restorative Dentistry & Endodontics.2019;[Epub]     CrossRef
• Comparison of Gap Volume after Retrofilling Using 4 Different Filling Materials: Evaluation by Micro–computed Tomography
  Sue Youn Kim, Hyeon-Cheol Kim, Su-Jung Shin, Euiseong Kim
  Journal of Endodontics.2018; 44(4): 635.     CrossRef
• Anti-inflammatory and Mineralization Effects of ProRoot MTA and Endocem MTA in Studies of Human and Rat Dental Pulps In Vitro and In Vivo
  Do-Hee Kim, Ji-Hyun Jang, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Sun-Hun Kim, Kyung-San Min, Jeong-Tae Koh, Yun-Chan Hwang
  Journal of Endodontics.2018; 44(10): 1534.     CrossRef
• Effects of Three Calcium Silicate Cements on Inflammatory Response and Mineralization-Inducing Potentials in a Dog Pulpotomy Model
  Chung-Min Kang, Jiwon Hwang, Je Seon Song, Jae-Ho Lee, Hyung-Jun Choi, Yooseok Shin
  Materials.2018; 11(6): 899.     CrossRef
• Cytocompatibility of Biodentine and iRoot FS with human periodontal ligament cells: an in vitro study
  T. Luo, J. Liu, Y. Sun, Y. Shen, L. Zou
  International Endodontic Journal.2018; 51(7): 779.     CrossRef
• Biological response of commercially available different tricalcium silicate-based cements and pozzolan cement
  Serhat Köseoğlu, Tuğba Pekbağryank, Ebru Kucukyilmaz, Mehmet Sağlam, Sukru Enhos, Ayşe Akgün
  Microscopy Research and Technique.2017; 80(9): 994.     CrossRef
• Biological efficacy of two mineral trioxide aggregate (MTA)-based materials in a canine model of pulpotomy
  Myeongyeon LEE, Chung-Min KANG, Je Seon SONG, Yooseok SHIN, Seunghye KIM, Seong-Oh KIM, Hyung-Jun CHOI
  Dental Materials Journal.2017; 36(1): 41.     CrossRef
• Cytotoxicities and genotoxicities of cements based on calcium silicate and of dental formocresol
  Hyunjung Ko, Youngdan Jeong, Miri Kim
  Mutation Research/Genetic Toxicology and Environmental Mutagenesis.2017; 815: 28.     CrossRef
• A Randomized Controlled Study of Mineral Trioxide Aggregate and Super Ethoxybenzoic Acid as Root-end Filling Materials in Endodontic Microsurgery: Long-term Outcomes
  Sunil Kim, Minju Song, Su-Jung Shin, Euiseong Kim
  Journal of Endodontics.2016; 42(7): 997.     CrossRef
• Effects of two fast-setting calcium-silicate cements on cell viability and angiogenic factor release in human pulp-derived cells
  Chooryung J. Chung, Euiseong Kim, Minju Song, Jeong-Won Park, Su-Jung Shin
  Odontology.2016; 104(2): 143.     CrossRef
• Cytotoxicity and Initial Biocompatibility of Endodontic Biomaterials (MTA and Biodentine™) Used as Root-End Filling Materials
  Diana María Escobar-García, Eva Aguirre-López, Verónica Méndez-González, Amaury Pozos-Guillén
  BioMed Research International.2016; 2016: 1.     CrossRef
• In Vitro Cytotoxicity Evaluation of Three Root-End Filling Materials in Human Periodontal Ligament Fibroblasts
  Hernán Coaguila-Llerena, Abraham Vaisberg, Zulema Velásquez-Huamán
  Brazilian Dental Journal.2016; 27(2): 187.     CrossRef
• Dynamic intratubular biomineralization following root canal obturation with pozzolan‐based mineral trioxide aggregate sealer cement
  Yeon‐Jee Yoo, Seung‐Ho Baek, Kee‐Yeon Kum, Won‐Jun Shon, Kyung‐Mi Woo, WooCheol Lee
  Scanning.2016; 38(1): 50.     CrossRef
• A Randomized Controlled Study of the Use of ProRoot Mineral Trioxide Aggregate and Endocem as Direct Pulp Capping Materials
  Minju Song, Minji Kang, Hyeon-Cheol Kim, Euiseong Kim
  Journal of Endodontics.2015; 41(1): 11.     CrossRef
• Comparative Analysis of Selected Physicochemical Properties of Pozzolan Portland and MTA-Based Cements
  Maura Cristiane Gonçales Orçati Dorileo, Ricardo Dalla Villa, Orlando Aguirre Guedes, Andreza Maria Fábio Aranha, Alex Semenoff-Segundo, Matheus Coelho Bandeca, Alvaro Henrique Borges
  International Scholarly Research Notices.2014; 2014: 1.     CrossRef
• Surgical endodontics: past, present, and future
  James L. Gutmann
  Endodontic Topics.2014; 30(1): 29.     CrossRef
• Comparative analysis of physicochemical properties of root perforation sealer materials
  Maura Cristiane Gonçales Orçati Dorileo, Fábio Luis Miranda Pedro, Matheus Coelho Bandeca, Orlando Aguirre Guedes, Ricardo Dalla Villa, Alvaro Henrique Borges
  Restorative Dentistry & Endodontics.2014; 39(3): 201.     CrossRef

When a patient with a fractured anterior tooth visits the clinic, clinician has to restore the tooth esthetically and quickly. For esthetic resin restoration, clinician can use 'Natural Layering technique' and an index for palatal wall may be needed. In this case report, we introduce pre-restoration index technique on a Class IV defect, in which a temporary filling material is used for easy restoration. Chair-side index fabrication for Class IV restoration is convenient and makes a single-visit treatment possible.

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• A digital workflow for layering composite resin restorations by using 3-dimensionally printed templates to replicate the contralateral tooth accurately and rapidly
  Junjing Zhang, Lin Fan, Chenyang Xie, Junying Li, Yuqiang Zhang, Haiyang Yu
  The Journal of Prosthetic Dentistry.2024; 131(5): 774.     CrossRef
• Combining a CAD-CAM composite resin palatal wall with a direct composite resin layering technique for the restoration of a large Class IV fracture: A clinical report
  Jingjin Liu, Junling Zhang, Weicai Liu, Shanshan Liang
  The Journal of Prosthetic Dentistry.2024;[Epub]     CrossRef
• Direct composite resin restoration of a class IV fracture by using 3D printing technology: A clinical report
  Yi Gao, Jiyao Li, Bo Dong, Min Zhang
  The Journal of Prosthetic Dentistry.2021; 125(4): 555.     CrossRef
• Esthetic rehabilitation of single anterior edentulous space using fiber-reinforced composite
  Hyeon Kim, Min-Ju Song, Su-Jung Shin, Yoon Lee, Jeong-Won Park
  Restorative Dentistry & Endodontics.2014; 39(3): 220.     CrossRef

The purpose of this study was to compare mineral trioxide aggregate (MTA; Dentsply, Tulsa Dental, Tulsa, OK, USA), which is widely used as root-end filling material, with DiaRoot BioAggregate (DB; Innovative BioCaramix Inc, Vancouver, BC, Canada), newly developed product, by using MG63 osteoblast-like cells. MTA, DB, and Intermediate Restorative Material (IRM; Dentsply Caulk, Milford, DE, USA) were used for root-end filling material while tissue culture plastic was used for control group. Each material was mixed and, the mixtures were left to set for 24 hours. MG63 cells were seeded to each group and then they were cultured for attachment for 4 hours. Following the attachment of cells to the root-end filling material, early cellular response was observed. After another 12 hours'culture, the level of attachment between cells and material was observed and in order to identify the effect of each material to bone formation, transforming growth factor beta1 (TGFβ1) and osteocalin (OC) were estimated by using enzyme-linked immunosorbent assay (ELISA), and the amount of alkaline phosphatase (ALP) was also measured. The data were analyzed using one-way ANOVA. As a result, only at OC and the number of cells which were attached to materials, there was no statistical difference between MTA and DB. At other items, there was statistically significant difference in all groups. Although DB has not shown exactly the same cellular response like that of MTA, the number of attached cells shows that biocompatibility of the material and OC indicates bone formation rate. Therefore, if DB is used for root end filling material, it is expected to lead to similar results to MTA.

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• Comparative analysis of physicochemical properties of root perforation sealer materials
  Maura Cristiane Gonçales Orçati Dorileo, Fábio Luis Miranda Pedro, Matheus Coelho Bandeca, Orlando Aguirre Guedes, Ricardo Dalla Villa, Alvaro Henrique Borges
  Restorative Dentistry & Endodontics.2014; 39(3): 201.     CrossRef
• Biocompatibility of root-end filling materials: recent update
  Payal Saxena, Saurabh Kumar Gupta, Vilas Newaskar
  Restorative Dentistry & Endodontics.2013; 38(3): 119.     CrossRef

We evaluated in vitro microleakage of Mineral Trioxide Aggregate (MTA) powder with 4-methacryloxyethyl trimellitate anhydride (4-META) / methyl methacrylate (MMA) & tri-n-butylborane (TBB) resin as a retrograde filling material by using methylene blue dye method.

Fifty-two single rooted, extracted teeth were instrumented and obturated with gutta percha and AH plus sealer. The apical 3mm of each root was resected and 3mm deep ultrasonic root end preparation was done. External surface of roots was coated with nail varnish. Prepared teeth were randomly divided into five groups; Negative control: completely covered with nail varnish; Positive control: coated with nail varnish except for apical foramen; Group 1 (retrofilled with Portland cement); Group 2 (retrofilled with MTA); Group 3 (retrofilled with MTA powder mixed with 4-META/MMA & TBB resin). Immediately after completion of root-end filling, all specimens were submerged in methylene blue dye for 72 hours in 37℃ incubator. The roots were longitudinally sectioned and measured for extent of dye penetration by three different examiners under microscope (×10). The results were statistically analyzed using one way ANOVA and Turkey's HSD test. No leakage was evident in negative control and complete leakage in positive control group. Group 3 showed significantly less leakage than group 1 and 2 (p < 0.01). There was no significant difference between group 1 and 2 (p > 0.01).

It was concluded that MTA powder with 4-META/MMA & TBB resin was excellent in reducing initial apical microleakage.

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• Characteristics of novel root-end filling material using epoxy resin and Portland cement
  Sang-Jin Lee, Jin Chung, Hee-Sam Na, Eun-Joo Park, Hyo-Jin Jeon, Hyeon-Cheol Kim
  Clinical Oral Investigations.2013; 17(3): 1009.     CrossRef
• Sealing Ability of Three Different Materials Used as Retrograde Filling
  Ji-Hoon Park, Seung-Bok Kang, Yong-Hoon Choi, Ji-Hyun Bae
  Journal of Korean Dental Science.2012; 5(2): 60.     CrossRef
• Physical properties of novel composite using Portland cement for retro-filling material
  Sang-Jin Lee, Ok-In Cho, Jiwan Yum, Jeong-Kil Park, Bock Hur, Hyeon-Cheol Kim
  Journal of Korean Academy of Conservative Dentistry.2010; 35(6): 445.     CrossRef

The purpose of this study was to measure the polymerization shrinkage and hygroscopic expansion of resin-based temporary filling materials and to evaluate microleakage at the interface between the materials and cavity wall.

Five resin-based temporary filing materials were investigated: Fermit (Vivadent), Quicks (Dentkist), Provifil (Promedica), Spacer (Vericom), Clip (Voco). Caviton (GC) was also included for comparison. Polymerization shrinkage of five resin-based temporary filling materials was measured using the bonded disc method. For the measurement of hygroscopic expansion, the discs of six cured temporary filling materials were immersed in saline and a LVDT displacement sensor was used to measure the expansion for 7 days. For estimating of microleakage, Class I cavities were prepared on 120 extracted human molars and randomly assigned to 6 groups of 20 each. The cavities in each group were filled with six temporary filling materials. All specimens were submitted to 1000 thermo-cycles, with temperature varying from 5℃/55℃. Microleakage was determined using a dye penetration test.

The results were as follows:

Fermit had significantly less polymerization shrinkage than the other resin-based temporary filling materials. Fermit (0.22 %) < Spacer (0.38 %) < Quicks (0.64 %), Provifil (0.67 %), Clip (0.67 %)

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• Comparison of color stability, gloss, mechanical and physical properties according to dental temporary filling materials type
  Ji-Won Choi, You-Young Shin, Song-Yi Yang
  Korean Journal of Dental Materials.2022; 49(3): 97.     CrossRef
• Comparative analysis of strain according to two wavelengths of light source and constant temperature bath deposition in ultraviolet-curing resin for dental three-dimensional printing
  Dong-Yeon Kim, Gwang-Young Lee, Hoo-Won Kang, Cheon-Seung Yang
  Journal of Korean Acedemy of Dental Technology.2020; 42(3): 208.     CrossRef
• Effect of cavity disinfectants on antibacterial activity and microtensile bond strength in class I cavity
  Bo-Ram KIM, Man-Hwan OH, Dong-Hoon SHIN
  Dental Materials Journal.2017; 36(3): 368.     CrossRef
• Shear bond strength of a self-adhesive resin cement to resin-coated dentin
  Jee-Youn Hong, Cheol-Woo Park, Jeong-Uk Heo, Min-Ki Bang, Jae-Jun Ryu
  The Journal of Korean Academy of Prosthodontics.2013; 51(1): 27.     CrossRef
• Coronal microleakage of four temporary restorative materials in Class II-type endodontic access preparations
  Sang-Mi Yun, Lorena Karanxha, Hee-Jin Kim, Sung-Ho Jung, Su-Jung Park, Kyung-San Min
  Restorative Dentistry & Endodontics.2012; 37(1): 29.     CrossRef
• Microtensile bond strength of resin inlay bonded to dentin treated with various temporary filling materials
  Tae-Woo Kim, Bin-Na Lee, Young-Jung Choi, So-Young Yang, Hoon-Sang Chang, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh
  Journal of Korean Academy of Conservative Dentistry.2011; 36(5): 419.     CrossRef
• The Effect of Temporary Filling Materials on The Adhesion between Dentin Adhesive-coated Surface and Resin Inlay
  Tae-Gun Kim, Kwang-Won Lee, Mi-Kyung Yu
  Journal of Korean Academy of Conservative Dentistry.2008; 33(6): 553.     CrossRef

This study was performed to assess the radiopacity of a variety of canal filling and retrograde root-end filling materials according to the specification concerning root canal obturation materials.

Ten materials including Gutta-percha pellets, amalgam, Fuji II LC, Dyract® AP, Super EBA®, IRM®, AH 26®, Sealapex™, Tubli-Seal™ and dentin were evaluated in this study. In the first part, densitometric reading of an each step of aluminum step wedge on occlusal film were performed at 60 kVp (0.2, 0.3, 0.4 s), 70 kVp (0.2, 0.3, 0.33 s) to decide appropriate voltage and exposure time. In the second part, ten specimens which are 5 mm in diameter and 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 mm in thickness, were fabricated from each material studied. The specimens were radiographed simultaneously with an aluminum step wedge under decided condition (60 kVp, 0.2 s). The mean radiographic density values of the materials were transformed into radiopacity expressed equivalent thickness of aluminum (mm Al).

The following results were obtained.

Among the various conditions including 0.2 s, 0.3 s, 0.4 s at 60 kVp and 0.2 s, 0.3 s, 0.33 s at 70 kVp, the appropriate voltage and exposure time that meet the requirement of density from 0.5 to 2.0 was 0.2 s at 60 kVp.

It suggests that all experimental canal filling and retrograde root-end filling materials have a sufficient radiopacity that meet the requirement concerning root canal obturation materials except for Fuji II LC and Dyract.

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• Evaluation of prognosis related to compliance with supportive periodontal treatment in patients with chronic periodontitis: a clinical retrospective study
  Jong-Bin Lee, Hye-Jung Shin, Dae-Yeob Kim, Eun-Kyoung Pang
  Journal of Periodontal & Implant Science.2019; 49(2): 76.     CrossRef

The purpose of this study was to evaluate the apical sealing ability of Super-EBA, MTA and Dyract-flow as retrofilling materials. Forty-eight extracted human teeth with straight and single root canal were used in this study. The root canals were prepared to a #40 apical canal size and obturated with gutter-percha. Apicoectomies were performed and root end cavities were prepared to a depth of 3mm using an ultrasonic device. The root end cavities were filled with Super-EBA, MTA or Dyract-flow. Leakage was measured using an electrochemical technique for 4 weeks.

According to this study, the results were as follows.

1. Increasing leakage with time was observed in all groups.

2. No significant difference was noted among the 3 groups with time (p = 0.216).

3. No significant difference was noted among the 3 groups when measured within the same time interval (p = 0.814).

The results of this study suggest that the sealing ability of Dyract-flow is equal to that of Super-EBA and MTA, and Dyract-flow may be an alternative to other materials for root-end filling.

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• Evaluation of Sealing Effect and Working Time of Root Canal Filling MTA Materials
  Hyojin Kim, Youngjin Kim, Soonhyeun Nam, Kwon Taeyub, Hyunjung Kim
  THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY.2016; 43(2): 129.     CrossRef
• Comparative analysis of physicochemical properties of root perforation sealer materials
  Maura Cristiane Gonçales Orçati Dorileo, Fábio Luis Miranda Pedro, Matheus Coelho Bandeca, Orlando Aguirre Guedes, Ricardo Dalla Villa, Alvaro Henrique Borges
  Restorative Dentistry & Endodontics.2014; 39(3): 201.     CrossRef

The purpose of this study is to evaluate the sealing effect of several root-end filling materials using spectrophotometric analysis. 180 single root teeth with one canal were instrumented and canal filled. Root resected and root end preparation was made. Teeth were randomly classified to 5 experimental group(MTA, EBA, IRM, TCP, ZOE) and 1 control group according to root-end filling material MTA group used PRO ROOT MTA, EBA group used Super EBA, TCP group used NEW APATITE LINER TYPE II main component of which is α-tricalcium phosphate(TCP). According to manufacture's instruction experimental material was mixed and retrfilled. After 2% methylene blue solution penetration absorbance for each test sample was measured with spectrophotometer (JASCO UV-530, Japan).

The mean absorbance of control and experimental group was as follows;

MTA : 0.092, IRM : 0.226, Super EBA : 0.255, ZOE : 0.374, Control : 0.425, TCP : 0.501 and the result analyzed by Turkey test at P=0.05 level.

Conclusions of this study are as follows;

The absorbance increase in follwing sequence MTA, IRM, Super EBA, ZOE, Control, TCP.