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Effects of CTHRC1 on odontogenic differentiation and angiogenesis in human dental pulp stem cells
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Jong-soon Kim, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2023;48(2):e18. Published online April 28, 2023
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DOI: https://doi.org/10.5395/rde.2023.48.e18
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Abstract
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- Objectives
This study aimed to determine whether collagen triple helix repeat containing-1 (CTHRC1), which is involved in vascular remodeling and bone formation, can stimulate odontogenic differentiation and angiogenesis when administered to human dental pulp stem cells (hDPSCs). Materials and MethodsThe viability of hDPSCs upon exposure to CTHRC1 was assessed with the WST-1 assay. CTHRC1 doses of 5, 10, and 20 µg/mL were administered to hDPSCs. Reverse-transcription polymerase reaction was used to detect dentin sialophosphoprotein, dentin matrix protein 1, vascular endothelial growth factor, and fibroblast growth factor 2. The formation of mineralization nodules was evaluated using Alizarin red. A scratch wound assay was conducted to evaluate the effect of CTHRC1 on cell migration. Data were analyzed using 1-way analysis of variance followed by the Tukey post hoc test. The threshold for statistical significance was set at p < 0.05. ResultsCTHRC1 doses of 5, 10, and 20 µg/mL had no significant effect on the viability of hDPSCs. Mineralized nodules were formed and odontogenic markers were upregulated, indicating that CTHRC1 promoted odontogenic differentiation. Scratch wound assays demonstrated that CTHRC1 significantly enhanced the migration of hDPSCs. ConclusionsCTHRC1 promoted odontogenic differentiation and mineralization in hDPSCs.
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Hard tissue formation after direct pulp capping with osteostatin and MTA in vivo
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Ji-Hye Yoon, Sung-Hyeon Choi, Jeong-Tae Koh, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2021;46(2):e17. Published online February 25, 2021
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DOI: https://doi.org/10.5395/rde.2021.46.e17
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In recent in vitro study, it was reported that osteostatin (OST) has an odontogenic effect and synergistic effect with mineral trioxide aggregate (MTA) in human dental pulp cells. Therefore, the aim of this study was to evaluate whether OST has a synergistic effect with MTA on hard tissue formation in vivo. Materials and MethodsThirty-two maxillary molars of Spraque-Dawley rats were used in this study. An occlusal cavity was prepared and the exposed pulps were randomly divided into 3 groups: group 1 (control; ProRoot MTA), group 2 (OST 100 μM + ProRoot MTA), group 3 (OST 10 mM + ProRoot MTA). Exposed pulps were capped with each material and cavities were restored with resin modified glass ionomer. The animals were sacrificed after 4 weeks. All harvested teeth were scanned with micro-computed tomography (CT). The samples were prepared and hard tissue formation was evaluated histologically. For immunohistochemical analysis, the specimens were sectioned and incubated with primary antibodies against dentin sialoprotein (DSP). ResultsIn the micro-CT analysis, it is revealed that OST with ProRoot MTA groups showed more mineralized bridge than the control (p < 0.05). In the H&E staining, it is showed that more quantity of the mineralized dentin bridge was formed in the OST with ProRoot MTA group compared to the control (p < 0.05). In all groups, DSP was expressed in newly formed reparative dentin area. ConclusionsOST can be a supplementary pulp capping material when used with MTA to make synergistic effect in hard tissue formation.
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Citations
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- Biocompatibility and pro-mineralization effects of premixed calcium silicate-based materials on human dental pulp stem cells: An in vitro and in vivo study
Nyein Chan KO, Sonoko NODA, Yamato OKADA, Kento TAZAWA, Nobuyuki KAWASHIMA, Takashi OKIJI Dental Materials Journal.2024; 43(5): 729. CrossRef - Osteostatin, a peptide for the future treatment of musculoskeletal diseases
Daniel Lozano, Arancha R. Gortazar, Sergio Portal-Núñez Biochemical Pharmacology.2024; 223: 116177. CrossRef - Comparison of bioactive material failure rates in vital pulp treatment of permanent matured teeth – a systematic review and network meta-analysis
Péter Komora, Orsolya Vámos, Noémi Gede, Péter Hegyi, Kata Kelemen, Adél Galvács, Gábor Varga, Beáta Kerémi, János Vág Scientific Reports.2024;[Epub] CrossRef - Hard tissue formation in pulpotomized primary teeth in dogs with nanomaterials MCM-48 and MCM-48/hydroxyapatite: an in vivo animal study
Sahar Talebi, Nosrat Nourbakhsh, Ardeshir Talebi, Amir Abbas Nourbakhsh, Abbas Haghighat, Maziar Manshayi, Hamid Reza Bakhsheshi, Razieh Karimi, Rahman Nazeri, Kenneth J.D. Mackenzie BMC Oral Health.2024;[Epub] CrossRef - Reparative Mineralized Tissue Characterization by Different Bioactive Direct Pulp-capping Agents
Mrunal Shinde, Varsha Pandit, Sarita Singh, Aniket Jadhav, Sarah Marium, Smita Patil Journal of the International Clinical Dental Research Organization.2024; 16(1): 8. CrossRef - Effects of mineral trioxide aggregate and methyl sulfonyl methane on pulp exposure via RUNX2 and RANKL pathways
Altar Ateş, Ayca Kurt, Tolga Mercantepe Odontology.2024; 112(3): 895. CrossRef - Effects of barium titanate on the dielectric constant, radiopacity, and biological properties of tricalcium silicate-based bioceramics
Yoorina CHOI, Yun-Chan HWANG, Mi-Kyung YU, Kwang-Won LEE, Kyung-San MIN Dental Materials Journal.2023; 42(1): 55. CrossRef - Bioactive potential of Bio‐C Pulpo is evidenced by presence of birefringent calcite and osteocalcin immunoexpression in the rat subcutaneous tissue
Marcela Borsatto Queiroz, Rafaela Nanami Handa Inada, Camila Soares Lopes, Juliane Maria Guerreiro‐Tanomaru, Estela Sasso‐Cerri, Mário Tanomaru‐Filho, Paulo Sérgio Cerri Journal of Biomedical Materials Research Part B: Applied Biomaterials.2022; 110(10): 2369. CrossRef - The Influence of New Bioactive Materials on Pulp–Dentin Complex Regeneration in the Assessment of Cone Bone Computed Tomography (CBCT) and Computed Micro-Tomography (Micro-CT) from a Present and Future Perspective—A Systematic Review
Mirona Paula Palczewska-Komsa, Bartosz Gapiński, Alicja Nowicka Journal of Clinical Medicine.2022; 11(11): 3091. CrossRef - A Breakthrough in the Era of Calcium Silicate-Based Cements: A Critical Review
Payal S Chaudhari, Manoj G Chandak, Akshay A Jaiswal, Nikhil P Mankar, Priyanka Paul Cureus.2022;[Epub] CrossRef - Effectiveness of Direct Pulp Capping Bioactive Materials in Dentin Regeneration: A Systematic Review
Ermin Nie, Jiali Yu, Rui Jiang, Xiangzhen Liu, Xiang Li, Rafiqul Islam, Mohammad Khursheed Alam Materials.2021; 14(22): 6811. CrossRef
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Oral manifestation and root canal therapy of the patient with mucopolysaccharidosis
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Ji-Hye Yoon, Hyo-Il Lee, Ji-Hyun Jang, Sung-Hyeon Choi, Hoon-Sang Chang, Yun-Chan Hwang, In-Nam Hwang, Bin-Na Lee, Won-Mann Oh
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Restor Dent Endod 2019;44(2):e14. Published online April 4, 2019
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DOI: https://doi.org/10.5395/rde.2019.44.e14
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Abstract
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Mucopolysaccharidosis (MPS) is an inherited metabolic disorder caused by a deficiency in enzymes that participate in the degradation of glycosaminoglycans (GAGs) such as heparin sulfate and dermatan sulfate. Left untreated, patients show progressive mental and physical deterioration due to deposition of GAGs in organs. Death often occurs due to cardiac or respiratory failure before patients reach their early twenties. MPS has several oral and dental manifestations. An enlarged head, short neck, and open mouth associated with a large tongue are major characteristics of MPS patients. Dental complications can be severe, including unerupted dentition, dentigerous cyst-like follicles, malocclusions, condylar defects, and gingival hyperplasia. A 21-year-old female patient with MPS was described in this article, with special emphasis on oral manifestations and dental treatment.
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- Pediatric Interventions in a Sanfilippo Syndrome Patient Under General Anesthesia: A Case Report
Ahmad Al Malak, Hassan Issawi, Mohammad Hassoun, Mohammad Al Halabi, Darko Macan Case Reports in Dentistry.2025;[Epub] CrossRef - Behavioural disorders and sleep problems in Sanfilippo syndrome: overlaps with some other conditions and importance indications
Karolina Wiśniewska, Jakub Wolski, Paulina Anikiej-Wiczenbach, Magdalena Żabińska, Grzegorz Węgrzyn, Karolina Pierzynowska European Child & Adolescent Psychiatry.2025;[Epub] CrossRef - Sanfilippo syndrome: consensus guidelines for clinical care
Nicole Muschol, Roberto Giugliani, Simon A. Jones, Joseph Muenzer, Nicholas J. C. Smith, Chester B. Whitley, Megan Donnell, Elise Drake, Kristina Elvidge, Lisa Melton, Cara O’Neill Orphanet Journal of Rare Diseases.2022;[Epub] CrossRef - Manifestaciones bucales de pacientes con mucopolisacaridosis. Serie de casos
Andrea Verónica Ríos, Mariana Llorensi Revista de la Asociación Odontológica Argentina.2021;[Epub] CrossRef
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Plugger temperature of cordless heat carriers according to the time elapsed
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Hoon-Sang Chang, Se-Hee Park, Kyung-Mo Cho, Jin-Woo Kim
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Restor Dent Endod 2018;43(1):e12. Published online February 7, 2018
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DOI: https://doi.org/10.5395/rde.2018.43.e12
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Abstract
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The purpose of this study was to measure the temperature of the plugger tip of 3 cordless heat carriers set at 200°C. Materials and MethodsPluggers of the same taper (0.06, 0.08, 0.10) and similar tip sizes (sizes of 50 and 55) from 3 cordless heat carriers, namely SuperEndo-α2 (B & L Biotech), Friendo (DXM), and Dia-Pen (Diadent), were used and an electric heat carrier, System B (SybronEndo), was used as the control. The plugger tips were covered with customized copper sleeves, heated for 10 seconds, and the temperature was recorded with a computerized measurement system attached to a K-type thermometer at room temperature (n = 10). The data were analyzed with 2-way analysis of variance at a 5% level of significance. ResultsThe peak temperature of the plugger tips was significantly affected by the plugger taper and by the heat carrier brand (p < 0.05). The peak temperature of the plugger tips was between 177°C and 325°C. The temperature peaked at 207°C–231°C for the 0.06 taper pluggers, 195°C–313°C for the 0.08 taper pluggers, and 177°C–325°C for the 0.10 taper pluggers. Only 5 of the 12 plugger tips showed a temperature of 200°C ± 10°C. The time required to reach the highest temperature or 200°C ± 10°C was at least 4 seconds. ConclusionWhen using cordless heat carriers, clinicians should pay attention to the temperature setting and to the activation time needed to reach the intended temperature of the pluggers.
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- Comparative Analysis of Temperature Variation with Three Continuous Wave Obturation Systems in Endodontics: An In Vitro Study
Jesús Mena-Álvarez, Maria Ruiz-Barrio, Norberto Quispe-López, Ana de Pedro-Muñoz, Cristina Rico-Romano Applied Sciences.2022; 12(12): 6229. CrossRef - Effect of Heat Softening versus Ultrasonic Removal of Root-End Gutta-Percha on the Quality of Root-End Preparation for Endodontic Microsurgery
Zhiting Ling, Ziting Zheng, Yuting Zeng, Lifang Jiang, Yuan Wu, Buling Wu, Wenjuan Yan, Lavinia C. Ardelean Scanning.2021; 2021: 1. CrossRef
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Dental management of patients with X-linked hypophosphatemia
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Bin-Na Lee, Hye-Yoon Jung, Hoon-Sang Chang, Yun-Chan Hwang, Won-Mann Oh
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Restor Dent Endod 2017;42(2):146-151. Published online January 6, 2017
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DOI: https://doi.org/10.5395/rde.2017.42.2.146
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X-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine, and an associated decrease in serum calcium and potassium phosphate. Its dental features include spontaneous dental abscesses that occur in the absence of trauma or dental caries. The aim of this case report was to describe the dental problems of XLH patients and to evaluate limitations in their treatment. A 14 year old male and a 38 year old female with XLH were referred to the Department of Conservative Dentistry for endodontic treatment. The dental findings were periapical abscesses without obvious trauma or caries. Conservative endodontic treatment was performed in teeth with pulp necrosis and abscess. In case 1, the treated teeth showed improvements in bone healing, without clinical symptoms. However, in case 2, the implants and the treated tooth showed hypermobility, and the final restoration was therefore postponed. Early diagnosis, periodic examinations, and communication with the patient's pediatrician are important in the dental management of patients with XLH.
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- Dental implant considerations in patients with systemic diseases: An updated comprehensive review
Seyed Ali Mosaddad, Sahar Talebi, Seied Omid Keyhan, Hamid Reza Fallahi, Mohammad Darvishi, Seyedeh Sara Aghili, Narges Tavahodi, Reza Abdollahi Namanloo, Artak Heboyan, Amirhossein Fathi Journal of Oral Rehabilitation.2024; 51(7): 1250. CrossRef - Inherited fibroblast growth factor 23 excess
Kripa Elizabeth Cherian, Thomas Vizhalil Paul Best Practice & Research Clinical Endocrinology & Metabolism.2024; 38(2): 101844. CrossRef - Dental abnormalities in rare genetic bone diseases: Literature review
Eiji Iwata, Shyam Kishor Sah, I‐Ping Chen, Ernst Reichenberger Clinical Anatomy.2024; 37(3): 304. CrossRef - Implant Survival in Patients with Chronic Kidney Disease: A Case Report and Systematic Review of the Literature
Iris Alla, Felice Lorusso, Sergio Alexandre Gehrke, Francesco Inchingolo, Maristella Di Carmine, Antonio Scarano International Journal of Environmental Research and Public Health.2023; 20(3): 2401. CrossRef - X-linked hypophosphatemic rickets: Orthodontic considerations and management. A case report
Clara Gibson, Suhaym Mubeen, Robert Evans Journal of Orthodontics.2022; 49(2): 205. CrossRef - X-chromosomale Hypophosphatämie (XLH)/Phosphatdiabetes – Eine lebenslange Erkrankung
Adalbert Raimann, Roland Kocijan, Gabriel T. Mindler Journal für Klinische Endokrinologie und Stoffwechsel.2022; 15(2): 63. CrossRef - Dental Manifestations and Oral Management of X-Linked Hypophosphatemia
Rena Okawa, Kazuhiko Nakano Endocrines.2022; 3(4): 654. CrossRef - Prospective Analysis of Muscle Adiposity in Children With X-linked Hypophosphatemic Rickets vs Control Children
Virginie Nguyen-Khac, Aurore Bonnet-Lebrun, Agnès Linglart, Marine de Tienda, Jugurtha Berkenou, Inès Mannes, Catherine Adamsbaum, Philippe Wicart, Wafa Skalli Journal of the Endocrine Society.2022;[Epub] CrossRef - Dental and periodontal features and management in XLH children and adults
Martin Biosse Duplan, Elvire Le Norcy, Frédéric Courson, Catherine Chaussain International Journal of Bone Fragility.2021; 1(2): 74. CrossRef - Hiding in plain sight: Gene panel and genetic markers reveal 26-year undiagnosed tumor-induced osteomalacia of the rib concurrently misdiagnosed as X-linked hypophosphatemia
Juan M. Colazo, Joseph A. DeCorte, Erin A. Gillaspie, Andrew L. Folpe, Kathryn M. Dahir Bone Reports.2021; 14: 100744. CrossRef - X-linked hypophosphatemia and burosumab: Practical clinical points from the French experience
Justine Bacchetta, Anya Rothenbuhler, Iva Gueorguieva, Peter Kamenicky, Jean-Pierre Salles, Karine Briot, Agnès Linglart Joint Bone Spine.2021; 88(5): 105208. CrossRef - Presentation and non‐surgical endodontic treatment of two patients with X‐linked hypophosphatemia: a case report
H. Bradley, A. Dutta, R. Philpott International Endodontic Journal.2021; 54(8): 1403. CrossRef - Periodontal status evaluation in adolescents with hereditary rickets-like diseases
E.V. Vislobokova, L.P. Kiselnikova, D.A. Lezhnev, S.S. Murtazaev, N.A. Sholokhova Stomatologiya.2021; 100(6): 63. CrossRef - Diagnosis, treatment-monitoring and follow-up of children and adolescents with X-linked hypophosphatemia (XLH)
Anya Rothenbuhler, Dirk Schnabel, Wolfgang Högler, Agnès Linglart Metabolism.2020; 103: 153892. CrossRef - Long-term outcomes for Asian patients with X-linked hypophosphataemia: rationale and design of the SUNFLOWER longitudinal, observational cohort study
Takuo Kubota, Seiji Fukumoto, Hae Il Cheong, Toshimi Michigami, Noriyuki Namba, Nobuaki Ito, Shin Tokunaga, Yoshimi Gibbs, Keiichi Ozono BMJ Open.2020; 10(6): e036367. CrossRef - X-Linked Hypophosphatemic Rickets Manifesting as Sclerotic Bone Disease and Enthesopathy
Hiya Boro, Shailendra Singh Naik, Charandeep Singh, Saurav Khatiwada, Rajesh Khadgawat Cureus.2020;[Epub] CrossRef - X-linked hypophosphatemia diagnosed after identification of dental symptoms
Kaoruko Wato, Rena Okawa, Saaya Matayoshi, Yuko Ogaya, Ryota Nomura, Kazuhiko Nakano Pediatric Dental Journal.2020; 30(2): 115. CrossRef - X-Linked Hypophosphatemia: A New Era in Management
Kathryn Dahir, Mary Scott Roberts, Stan Krolczyk, Jill H Simmons Journal of the Endocrine Society.2020;[Epub] CrossRef - Prosthetic rehabilitation of a patient with X-linked hypophosphatemia using dental implants: a case report and review of the literature
Martin James, Reza Vahid Roudsari International Journal of Implant Dentistry.2019;[Epub] CrossRef - Oral symptoms and oral health-related quality of life of individuals with x-linked hypophosphatemia
Marcel Hanisch, Lauren Bohner, Martin M. I. Sabandal, Johannes Kleinheinz, Susanne Jung Head & Face Medicine.2019;[Epub] CrossRef - Outcome of adult patients with X‐linked hypophosphatemia caused by PHEX gene mutations
Douglas Chesher, Michael Oddy, Ulpee Darbar, Parag Sayal, Adrian Casey, Aidan Ryan, Annalisa Sechi, Charlotte Simister, Aoife Waters, Yehani Wedatilake, Robin H. Lachmann, Elaine Murphy Journal of Inherited Metabolic Disease.2018; 41(5): 865. CrossRef
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Evaluation of reparative dentin formation of ProRoot MTA, Biodentine and BioAggregate using micro-CT and immunohistochemistry
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Jia Kim, Young-Sang Song, Kyung-San Min, Sun-Hun Kim, Jeong-Tae Koh, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2016;41(1):29-36. Published online January 4, 2016
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DOI: https://doi.org/10.5395/rde.2016.41.1.29
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The purpose of this study was to assess the ability of two new calcium silicate-based pulp-capping materials (Biodentine and BioAggregate) to induce healing in a rat pulp injury model and to compare them with mineral trioxide aggregate (MTA). Materials and MethodsEighteen rats were anesthetized, cavities were prepared and the pulp was capped with either of ProRoot MTA, Biodentine, or BioAggregate. The specimens were scanned using a high-resolution micro-computed tomography (micro-CT) system and were prepared and evaluated histologically and immunohistochemically using dentin sialoprotein (DSP). ResultsOn micro-CT analysis, the ProRoot MTA and Biodentine groups showed significantly thicker hard tissue formation (p < 0.05). On H&E staining, ProRoot MTA showed complete dentin bridge formation with normal pulpal histology. In the Biodentine and BioAggregate groups, a thick, homogeneous hard tissue barrier was observed. The ProRoot MTA specimens showed strong immunopositive reaction for DSP. ConclusionsOur results suggest that calcium silicate-based pulp-capping materials induce favorable effects on reparative processes during vital pulp therapy and that both Biodentine and BioAggregate could be considered as alternatives to ProRoot MTA.
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Treatment of non-vital immature teeth with amoxicillin-containing triple antibiotic paste resulting in apexification
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Hyon-Beom Park, Bin-Na Lee, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh, Hoon-Sang Chang
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Restor Dent Endod 2015;40(4):322-327. Published online August 28, 2015
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DOI: https://doi.org/10.5395/rde.2015.40.4.322
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Abstract
PDF PubReader ePub
A recent treatment option for non-vital immature teeth in young patients is revascularization with triple antibiotic paste (TAP). However, tooth discoloration was reported with the use of conventional minocycline-containing TAP. In this case report, amoxicillin-containing TAP was used for revascularization of non-vital immature teeth to prevent tooth discoloration. At the 1 yr follow up, the teeth were asymptomatic on clinical examination and showed slight discoloration of the crown due to mineral trioxide aggregate (MTA) filling rather than amoxicillin-containing TAP. Radiographic examination revealed complete resolution of the periapical radiolucency, and closed apex with obvious periodontal ligament space. However, the root growth was limited, and the treatment outcome was more like apexification rather than revascularization. These results may be due to unstable blood clot formation which could not resist the condensation force of MTA filling, whether or not a collagen matrix was in place. These cases showed that although revascularization was not successful, apexification could be expected, resulting in the resolution of the periapical radiolucency and the closure of the apex. Therefore, it is worthwhile attempting revascularization of non-vital immature teeth in young patients.
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Citations
Citations to this article as recorded by 
- Comparative evaluation of effect of modified triple antibiotic paste and calcium hydroxide as intracanal medicament on microhardness of root dentin: An in vitro study
Aparna Palekar, Piyush Mantri, Minal Awinashe, Basawaraj Biradar, Mukund Singh Endodontology.2024;[Epub] CrossRef - Healing of Large Endodontic Lesions Using Long-Term Application of a New Combination of Triple Antibiotics: A Series of Cases
Saeed Asgary, Ardavan Parhizkar, Maria Beatriz Duarte Gavião Case Reports in Dentistry.2023; 2023: 1. CrossRef - Comparative Evaluation of Two Antibiotic Pastes for Root Canal Disinfection
Sadhna Sharma, Urvashi Bhushan, Mridula Goswami, CP Baveja International Journal of Clinical Pediatric Dentistry.2022; 15(S1): S12. CrossRef - Regenerative Endodontics as the Future Treatment of Immature Permanent Teeth
Justyna Zbańska, Katarzyna Herman, Piotr Kuropka, Maciej Dobrzyński Applied Sciences.2021; 11(13): 6211. CrossRef - Antimicrobial efficacy of triple antibiotic paste in teeth with primary endodontic infection: A systematic review
Rhythm Bains, Aseem P. Tikku, Promila Verma, Pragya Pandey Asian Journal of Oral Health and Allied Sciences.2021; 11: 2. CrossRef - Effectiveness of MTA apical plug in dens evaginatus with open apices
Khoa Van Pham, Thu Anh Tran BMC Oral Health.2021;[Epub] CrossRef - Lesion Sterilization and Tissue Repair: A Literature Review
Ankit Rawat, Jyoti Nagpal, Shreeya Mehta, Divya Vyas, Abhishek Kumar, Fathima Amal Journal of Research and Advancement in Dentistry.2021; 12(3): 6. CrossRef - Spectrophotometric assessment of Tooth discoloration induced by various Antibiotic pastes
Ravi Gupta, Radhika Kewalramani, Dishant Patel Research Journal of Pharmacy and Technology.2021; : 1979. CrossRef - Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study
PoojaNitin Mapara, ND Shashikiran, Sachin Gugawad, Namrata Gaonkar, Savita Hadakar, Swapnil Taur, Dhanshri Khade Journal of Indian Society of Pedodontics and Preventive Dentistry.2020; 38(2): 132. CrossRef - Effect of triple antibiotic loaded apatitic nanocarriers on Enterococcus faecalis biofilm – An In vitro study
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Noushin Shokouhinejad, Hassan Razmi, Maryam Farbod, Marzieh Alikhasi, Josette Camilleri Restorative Dentistry & Endodontics.2019;[Epub] CrossRef - Triple antibiotic paste: momentous roles and applications in endodontics: a review
Ardavan Parhizkar, Hanieh Nojehdehian, Saeed Asgary Restorative Dentistry & Endodontics.2018;[Epub] CrossRef - Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview – part II: other clinical applications and complications
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Luciane Geanini Pena dos Santos, Luiz Alexandre Chisini, Camila Guerner Springmann, Beatriz Dulcineia Mendes de Souza, Fernanda Geraldo Pappen, Flávio Fernando Demarco, Mara Cristina Santos Felippe, Wilson Tadeu Felippe Brazilian Dental Journal.2018; 29(5): 409. CrossRef - Regenerative Endodontic Treatment or Mineral Trioxide Aggregate Apical Plug in Teeth with Necrotic Pulps and Open Apices: A Systematic Review and Meta-analysis
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López Carmen, Mendoza Asunción, Solano Beatriz, Yáñez-Vico Rosa Case Reports in Dentistry.2017; 2017: 1. CrossRef
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A review of the regenerative endodontic treatment procedure
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Bin-Na Lee, Jong-Wook Moon, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2015;40(3):179-187. Published online March 16, 2015
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DOI: https://doi.org/10.5395/rde.2015.40.3.179
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Abstract
PDF PubReader ePub
Traditionally, apexification has been used to treat immature permanent teeth that have lost pulp vitality. This technique promotes the formation of an apical barrier to close the open apex so that the filling materials can be confined to the root canal. Because tissue regeneration cannot be achieved with apexification, a new technique called regenerative endodontic treatment was presented recently to treat immature permanent teeth. Regenerative endodontic treatment is a treatment procedure designed to replace damaged pulp tissue with viable tissue which restores the normal function of the pulp-dentin structure. After regenerative endodontic treatment, continued root development and hard tissue deposition on the dentinal wall can occur under ideal circumstances. However, it is difficult to predict the result of regenerative endodontic treatment. Therefore, the purpose of this study was to summarize multiple factors effects on the result of regenerative endodontic treatment in order to achieve more predictable results. In this study, we investigated the features of regenerative endodontic treatment in comparison with those of other pulp treatment procedures and analyzed the factors that have an effect on regenerative endodontic treatment.
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Kristina Feigin, Bonnie Shope Journal of Veterinary Dentistry.2017; 34(3): 161. CrossRef - Intentional Replantation of an Avulsed Immature Permanent Incisor: A Case Report
Claudio Maniglia-Ferreira, Fabio de Almeida Gomes, Marcelo de Morais Vitoriano Journal of Endodontics.2017; 43(8): 1383. CrossRef - Effect of acidic solutions on the microhardness of dentin and set OrthoMTA and their cytotoxicity on murine macrophage
Soram Oh, Hiran Perinpanayagam, Yoon Lee, Jae-Won Kum, Yeon-Jee Yoo, Sang-Min Lim, Seok Woo Chang, Won-Jun Shon, Woocheol Lee, Seung-Ho Baek, Kee-Yeon Kum Restorative Dentistry & Endodontics.2016; 41(1): 12. CrossRef - Questioning the spot light on Hi-tech endodontics
Jojo Kottoor, Denzil Albuquerque Restorative Dentistry & Endodontics.2016; 41(1): 80. CrossRef - Effects of a Bioactive Scaffold Containing a Sustained Transforming Growth Factor-β1–releasing Nanoparticle System on the Migration and Differentiation of Stem Cells from the Apical Papilla
Craig Bellamy, Suja Shrestha, Calvin Torneck, Anil Kishen Journal of Endodontics.2016; 42(9): 1385. CrossRef - Effects of Novel 3-dimensional Antibiotic-containing Electrospun Scaffolds on Dentin Discoloration
Margaret Louise A. Porter, Eliseu A. Münchow, Maria T.P. Albuquerque, Kenneth J. Spolnik, Anderson T. Hara, Marco C. Bottino Journal of Endodontics.2016; 42(1): 106. CrossRef
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Changes in SIRT gene expression during odontoblastic differentiation of human dental pulp cells
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Young-Eun Jang, Su-Hee Go, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2015;40(3):223-228. Published online July 15, 2015
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DOI: https://doi.org/10.5395/rde.2015.40.3.223
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Abstract
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- Objectives
The aim of this study was to investigate the expression of 7 different sirtuin genes (SIRT1-SIRT7) in human dental pulp cells (HDPCs), and to determine the role of SIRTs in the odontoblastic differentiation potential of HDPCs. Materials and MethodsHDPCs were isolated from freshly extracted third molar teeth of healthy patients and cultulred in odontoblastic differentiation inducing media. Osteocalcin (OCN) and dentin sialophosphoprotein (DSPP) expression was analyzed to evaluate the odontoblastic differentiation of HDPCs by reverse transcription-polymerase chain reaction (RT-PCR), while alizarin red staining was used for the mineralization assay. To investigate the expression of SIRTs during odontoblastic differentiation of HDPCs, real time PCR was also performed with RT-PCR. ResultsDuring the culture of HDPCs in the differentiation inducing media, OCN, and DSPP mRNA expressions were increased. Mineralized nodule formation was also increased in the 14 days culture. All seven SIRT genes were expressed during the odontogenic induction period. SIRT4 expression was increased in a time-dependent manner. ConclusionsOur study identified the expression of seven different SIRT genes in HDPCs, and revealed that SIRT4 could exert an influence on the odontoblast differentiation process. Further studies are needed to determine the effects of other SIRTs on the odontogenic potential of HDPCs.
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- Biodegradable Zn‐5Dy Alloy with Enhanced Osteo/Angio‐Genic Activity and Osteointegration Effect via Regulation of SIRT4‐Dependent Mitochondrial Function
Yue Han, Xian Tong, Runqi Zhou, Yilin Wang, Yuge Chen, Liang Chen, Xinhua Hong, Linmei Wu, Zhiqiang Lin, Yichi Zhang, Xuejia Zhang, Chaoming Hu, Bin Li, Yifan Ping, Zelin Cao, Zhou Ye, Zhongchen Song, Yuncang Li, Cuie Wen, Yongsheng Zhou, Jixing Lin, Shen Advanced Science.2024;[Epub] CrossRef - The Role of Histone Acetylation Modification in Dental Tissue-Derived Mesenchymal Stem Cells and Odontogenesis
Haoling Chen, Zijing Huang, Chuxiao Chen Cellular Reprogramming.2023; 25(1): 11. CrossRef - Metabolic Remodeling Impacts the Epigenetic Landscape of Dental Mesenchymal Stem Cells
Haiyun Luo, Yachuan Zhou, Wenjing Liu, Jun Wang Stem Cells International.2022; 2022: 1. CrossRef - SIRT4 regulates rat dental papilla cell differentiation by promoting mitochondrial functions
Haoling Chen, Jun Kang, Fuping Zhang, Tong Yan, Wenguo Fan, Hongwen He, Fang Huang The International Journal of Biochemistry & Cell Biology.2021; 134: 105962. CrossRef - Sirtuins as Interesting Players in the Course of HIV Infection and Comorbidities
Karolina Jurkowska, Beata Szymańska, Brygida Knysz, Amadeusz Kuźniarski, Agnieszka Piwowar Cells.2021; 10(10): 2739. CrossRef - Robust expression of SIRT6 inhibits pulpitis via activation of the TRPV1 channel
Jia Hu, Weiran Chen, Zailing Qiu, Hongbing Lv Cell Biochemistry and Function.2020; 38(5): 676. CrossRef - Downregulation of microRNA‐143‐5p is required for the promotion of odontoblasts differentiation of human dental pulp stem cells through the activation of the mitogen‐activated protein kinases 14‐dependent p38 mitogen‐activated protein kinases signaling pa
Bao‐Liang Wang, Zhi Wang, Xi Nan, Qing‐Cai Zhang, Wei Liu Journal of Cellular Physiology.2019; 234(4): 4840. CrossRef - A potential role for the silent information regulator 2 homologue 1 (SIRT1) in periapical periodontitis
H. Kudo, O. Takeichi, K. Hatori, K. Makino, K. Himi, B. Ogiso International Endodontic Journal.2018; 51(7): 747. CrossRef - Overexpressed Sirt1 in MSCs Promotes Dentin Formation in Bmi1-Deficient Mice
H. Wang, C. Lv, Y. Gu, Q. Li, L. Xie, H. Zhang, D. Miao, W. Sun Journal of Dental Research.2018; 97(12): 1365. CrossRef - Expression of silent information regulator 2 homolog 1 (SIRT1) in periapical granulomas
Hiroshi Kudo, Osamu Takeichi, Kosuke Makino, Keisuke Hatori, Bunnai Ogiso Journal of Oral Science.2018; 60(3): 411. CrossRef - TET1 knockdown inhibits the odontogenic differentiation potential of human dental pulp cells
Li-Jia Rao, Bai-Cheng Yi, Qi-Meng Li, Qiong Xu International Journal of Oral Science.2016; 8(2): 110. CrossRef
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Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials
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Young-Eun Jang, Bin-Na Lee, Jeong-Tae Koh, Yeong-Joon Park, Nam-Eok Joo, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2014;39(2):89-94. Published online March 21, 2014
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DOI: https://doi.org/10.5395/rde.2014.39.2.89
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Abstract
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- Objectives
The aim of this study was to evaluate the cytotoxicity, setting time and compressive strength of MTA and two novel tricalcium silicate-based endodontic materials, Bioaggregate (BA) and Biodentine (BD). Materials and MethodsCytotoxicity was evaluated by using a 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide (XTT) assay. Measurements of 9 heavy metals (arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel, and zinc) were performed by inductively coupled plasma-mass spectrometry (ICP-MS) of leachates obtained by soaking the materials in distilled water. Setting time and compressive strength tests were performed following ISO requirements. ResultsBA had comparable cell viability to MTA, whereas the cell viability of BD was significantly lower than that of MTA. The ICP-MS analysis revealed that BD released significantly higher amount of 5 heavy metals (arsenic, copper, iron, manganese, and zinc) than MTA and BA. The setting time of BD was significantly shorter than that of MTA and BA, and the compressive strength of BA was significantly lower than that of MTA and BD. ConclusionsBA and BD were biocompatible, and they did not show any cytotoxic effects on human periodontal ligament fibroblasts. BA showed comparable cytotoxicity to MTA but inferior physical properties. BD had somewhat higher cytotoxicity but superior physical properties than MTA.
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Paridhi Agrawal, Manoj Chandak, Aditya Patel, Jay Bhopatkar BMC Oral Health.2024;[Epub] CrossRef - Evaluation of bioactivity, biocompatibility, and antibacterial properties of tricalcium silicate bone cement modified with wollastonite/ fluorapatite glass and glass-ceramic
H.K. Abd El-Hamid, A.M. Fayad, R.L. Elwan Ceramics International.2024; 50(14): 25322. CrossRef - Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study
Monthip Wannakajeepiboon, Chankhrit Sathorn, Chatvadee Kornsuthisopon, Busayarat Santiwong, Thanakorn Wasanapiarnpong, Pairoj Linsuwanont BMC Oral Health.2023;[Epub] CrossRef - Strength of a cement-based dental material: Early age testing and first micromechanical modeling at mature age
Petr Dohnalík, Christian Hellmich, Gilles Richard, Bernhard L. A. Pichler Frontiers in Bioengineering and Biotechnology.2023;[Epub] CrossRef - Calcium silicate and calcium aluminate cements for dentistry reviewed
Carolyn Primus, James L. Gutmann, Franklin R. Tay, Anna B. Fuks Journal of the American Ceramic Society.2022; 105(3): 1841. CrossRef - Biomimetic Approaches in Clinical Endodontics
Naresh Kumar, Nazrah Maher, Faiza Amin, Hani Ghabbani, Muhammad Sohail Zafar, Francisco Javier Rodríguez-Lozano, Ricardo E. Oñate-Sánchez Biomimetics.2022; 7(4): 229. CrossRef - Effect of different manipulations on the physical, chemical and microstructural characteristics of Biodentine
Mariana Domingos Pires, Joana Cordeiro, Isabel Vasconcelos, Mariana Alves, Sérgio André Quaresma, António Ginjeira, Josette Camilleri Dental Materials.2021; 37(7): e399. CrossRef - Minimal Intervention in Dentistry: A Literature Review on Biodentine as a Bioactive Pulp Capping Material
Naji Ziad Arandi, Mohammad Thabet, Mona Abbassy BioMed Research International.2021;[Epub] CrossRef - Chitosan-Based Accelerated Portland Cement Promotes Dentinogenic/Osteogenic Differentiation and Mineralization Activity of SHED
Hasan Subhi, Adam Husein, Dasmawati Mohamad, Nik Rozainah Nik Abdul Ghani, Asma-Abdullah Nurul Polymers.2021; 13(19): 3358. CrossRef - Material Pulp Cells and Tissue Interactions
Nastaran Meschi, Biraj Patel, Nikita B. Ruparel Journal of Endodontics.2020; 46(9): S150. CrossRef - Biological Effects of Tricalcium Silicate Nanoparticle-Containing Cement on Stem Cells from Human Exfoliated Deciduous Teeth
Yoonsun Jung, Ji-Young Yoon, Kapil Dev Patel, Lan Ma, Hae-Hyoung Lee, Jongbin Kim, Jung-Hwan Lee, Jisun Shin Nanomaterials.2020; 10(7): 1373. CrossRef - Physicochemical, mechanical and cytotoxicity evaluation of chitosan-based accelerated portland cement
Hasan Subhi, Adam Husein, Dasmawati Mohamad, Asma-Abdullah Nurul Journal of Materials Research and Technology.2020; 9(5): 11574. CrossRef - Tricalcium silicate cements: osteogenic and angiogenic responses of human bone marrow stem cells
Mohamed R. W. Ali, Manal Mustafa, Asgeir Bårdsen, Athanasia Bletsa European Journal of Oral Sciences.2019; 127(3): 261. CrossRef - Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues
Carolyn M. Primus, Franklin R. Tay, Li-na Niu Acta Biomaterialia.2019; 96: 35. CrossRef - Effect of phytic acid on the setting times and tensile strengths of calcium silicate‐based cements
Ozgur Uyanik, Emre Nagas, Selen Kucukkaya Eren, Zafer C. Cehreli, Pekka K. Vallittu, Lippo V.J. Lassila Australian Endodontic Journal.2019; 45(2): 241. CrossRef - Effects of four novel root-end filling materials on the viability of periodontal ligament fibroblasts
Makbule Bilge Akbulut, Pembegul Uyar Arpaci, Ayce Unverdi Eldeniz Restorative Dentistry & Endodontics.2018;[Epub] CrossRef - Biodentine™ material characteristics and clinical applications: a 3 year literature review and update
S. Rajasekharan, L. C. Martens, R. G. E. C. Cauwels, R. P. Anthonappa European Archives of Paediatric Dentistry.2018; 19(1): 1. CrossRef - Root perforations: a review of diagnosis, prognosis and materials
Carlos Estrela, Daniel de Almeida Decurcio, Giampiero Rossi-Fedele, Julio Almeida Silva, Orlando Aguirre Guedes, Álvaro Henrique Borges Brazilian Oral Research.2018;[Epub] CrossRef - Effects of chelating agent and acids on Biodentine
V Ballal, JN Marques, CN Campos, CO Lima, RA Simão, M Prado Australian Dental Journal.2018; 63(2): 170. CrossRef - Biological interactions of a calcium silicate based cement (Biodentine™) with Stem Cells from Human Exfoliated Deciduous teeth
Eirini Athanasiadou, Maria Paschalidou, Anna Theocharidou, Nikolaos Kontoudakis, Konstantinos Arapostathis, Athina Bakopoulou Dental Materials.2018; 34(12): 1797. CrossRef - Retention of BioAggregate and MTA as coronal plugs after intracanal medication for regenerative endodontic procedures: an ex vivo study
Suzan Abdul Wanees Amin, Shaimaa Ismail Gawdat Restorative Dentistry & Endodontics.2018;[Epub] CrossRef - Management of Dens Invaginatus Type II Associated with Immature Apex and Large Periradicular Lesion Using Platelet-rich Fibrin and Biodentine
Shruti Goel, Ruchika Roongta Nawal, Sangeeta Talwar Journal of Endodontics.2017; 43(10): 1750. CrossRef - Brain aluminium accumulation and oxidative stress in the presence of calcium silicate dental cements
K Demirkaya, B Can Demirdöğen, Z Öncel Torun, O Erdem, E Çırak, YM Tunca Human & Experimental Toxicology.2017; 36(10): 1071. CrossRef - Calcium silicate‐based cements: composition, properties, and clinical applications
Alaa E. Dawood, Peter Parashos, Rebecca H.K. Wong, Eric C. Reynolds, David J. Manton Journal of Investigative and Clinical Dentistry.2017;[Epub] CrossRef - Biological response of commercially available different tricalcium silicate-based cements and pozzolan cement
Serhat Köseoğlu, Tuğba Pekbağryank, Ebru Kucukyilmaz, Mehmet Sağlam, Sukru Enhos, Ayşe Akgün Microscopy Research and Technique.2017; 80(9): 994. CrossRef - Modified tricalcium silicate cement formulations with added zirconium oxide
Xin Li, Kumiko Yoshihara, Jan De Munck, Stevan Cokic, Pong Pongprueksa, Eveline Putzeys, Mariano Pedano, Zhi Chen, Kirsten Van Landuyt, Bart Van Meerbeek Clinical Oral Investigations.2017; 21(3): 895. CrossRef - Cytotoxic effects of mineral trioxide aggregate, calcium enrichedmixture cement, Biodentine and octacalcium pohosphate onhuman gingival fibroblasts
Eshagh A. Saberi, Narges Farhadmollashahi, Faroogh Ghotbi, Hamed Karkeabadi, Roholla Havaei Journal of Dental Research, Dental Clinics, Dental Prospects.2016; 10(2): 75. CrossRef - The effect of working time on the displacement of Biodentine™ beneath prefabricated stainless steel crown: a laboratory study
Alaa E. Dawood, David J. Manton, Peter Parashos, Rebecca H. K. Wong Journal of Investigative and Clinical Dentistry.2016; 7(4): 391. CrossRef - Evaluation of reparative dentin formation of ProRoot MTA, Biodentine and BioAggregate using micro-CT and immunohistochemistry
Jia Kim, Young-Sang Song, Kyung-San Min, Sun-Hun Kim, Jeong-Tae Koh, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang Restorative Dentistry & Endodontics.2016; 41(1): 29. CrossRef
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Autogenous tooth transplantation for replacing a lost tooth: case reports
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Ji-Youn Kang, Hoon-Sang Chang, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh, Bin-Na Lee
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Restor Dent Endod 2013;38(1):48-51. Published online February 26, 2013
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DOI: https://doi.org/10.5395/rde.2013.38.1.48
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The autogenous tooth transplantation is an alternative treatment replacing a missing tooth when a suitable donor tooth is available. It is also a successful treatment option to save significant amount of time and cost comparing implants or conventional prosthetics. These cases, which required single tooth extraction due to deep caries and severe periodontal disease, could have good results by transplanting non-functional but sound donor tooth to the extraction site.
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- Autogenous Tooth Transplantation of Canines—A Prospective Clinical Study on the Influence of Adjunctive Antibiosis and Patient-Related Risk Factors During Initial Healing
Sebastian Meinzer, Dirk Nolte, Karin Christine Huth Journal of Clinical Medicine.2025; 14(3): 821. CrossRef - 13-year follow-up of autotransplantation using an immature third molar: a case report
Hojin Moon Journal of Dental Rehabilitation and Applied Science.2025; 41(1): 72. CrossRef - Dental autotransplantation: case report and follow-up
Kassandra García Covarrubias, Erika Etcheverry Doger, Jennifer Antón Sarabia, Mario Alberto Lagunes López Revista Odontología Pediátrica.2024;[Epub] CrossRef - Analysis and evaluation of the effectiveness of autotransplantation of teeth
Filipp V. Dulov, Roman B. Gurkin, Ekaterina S. Derbentsova, Ulia V. Budanova Russian Journal of Dentistry.2023; 27(3): 193. CrossRef - Pre- and peri-operative factors influence autogenous tooth transplantation healing in insufficient bone sites
Thanapon Suwanapong, Aurasa Waikakul, Kiatanant Boonsiriseth, Nisarat Ruangsawasdi BMC Oral Health.2021;[Epub] CrossRef - Third molar autotransplantation: An alternative to dental implant - 9 years follow up of a case
Sanjay Kumar, Mansi Jain, Suma Sogi, Prinka Shahi, Saru Dhir, Swati Rana Annals of Maxillofacial Surgery.2020; 10(2): 529. CrossRef - Prognostic Factors for Clinical Outcomes in Autotransplantation of Teeth with Complete Root Formation: Survival Analysis for up to 12 Years
Youngjune Jang, Yoon Jeong Choi, Seung-Jong Lee, Byoung-Duck Roh, Sang Hyuk Park, Euiseong Kim Journal of Endodontics.2016; 42(2): 198. CrossRef - Post-Odontoma autotransplantation of an impacted tooth: A case report
Waikhom Robindro Singh, Kirankumar Aheibam, Anthopia Nameirakpam Journal of Oral Biology and Craniofacial Research.2015; 5(2): 120. CrossRef - Autotransplantation of a Mandibular Third Molar: A Case Report with 5 Years of Follow-up
Mauro Henrique Chagas e Silva, Mariane Floriano Lopes Santos Lacerda, Maria das Gracas Afonso Miranda Chaves, Celso Neiva Campos Brazilian Dental Journal.2013; 24(3): 289. CrossRef
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Power density of various light curing units through resin inlays with modified layer thickness
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Sung-Ok Hong, Yonghui Oh, Jeong-Bum Min, Jin-Woo Kim, Bin-Na Lee, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh, Hoon-Sang Chang
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Restor Dent Endod 2012;37(3):130-135. Published online August 29, 2012
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DOI: https://doi.org/10.5395/rde.2012.37.3.130
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Abstract
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- Objectives
The purpose of this study was to enhance curing light penetration through resin inlays by modifying the thicknesses of the dentin, enamel, and translucent layers. Materials and MethodsTo investigate the layer dominantly affecting the power density of light curing units, resin wafers of each layer with 0.5 mm thickness were prepared and power density through resin wafers was measured with a dental radiometer (Cure Rite, Kerr). The dentin layer, which had the dominant effect on power density reduction, was decreased in thickness from 0.5 to 0.1 mm while thickness of the enamel layer was kept unchanged at 0.5 mm and thickness of the translucent layer was increased from 0.5 to 0.9 mm and vice versa, in order to maintain the total thickness of 1.5 mm of the resin inlay. Power density of various light curing units through resin inlays was measured. ResultsPower density measured through 0.5 mm resin wafers decreased more significantly with the dentin layer than with the enamel and translucent layers (p < 0.05). Power density through 1.5 mm resin inlays increased when the dentin layer thickness was reduced and the enamel or translucent layer thickness was increased. The highest power density was recorded with dentin layer thickness of 0.1 mm and increased translucent layer thickness in all light curing units. ConclusionsTo enhance the power density through resin inlays, reducing the dentin layer thickness and increasing the translucent layer thickness would be recommendable when fabricating resin inlays.
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Citations
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- Effects of layering technique on the shade of resin overlays and the microhardness of dual cure resin cement
Hoon-Sang Chang, Sung-Ok Hong Brazilian Oral Research.2014;[Epub] CrossRef - Early Hardness and Shear Bond Strength of Dual-cure Resin Cement Light Cured Through Resin Overlays With Different Dentin-layer Thicknesses
H-S Chang, J-W Kim Operative Dentistry.2014; 39(4): 398. CrossRef - Light curing of dual cure resin cement
Hoon-Sang Chang Restorative Dentistry & Endodontics.2013; 38(4): 266. CrossRef
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Colorimetric comparison of single layered dental composite with double layered dental composite
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Young-Sang Song, Ja-Hyun Kim, Bin-Na Lee, Ji-Hyun Jang, Hoon-Sang Chang, Yun-Chan Hwang, Won-Mann Oh, In-Nam Hwang
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Restor Dent Endod 2012;37(2):84-89. Published online May 18, 2012
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DOI: https://doi.org/10.5395/rde.2012.37.2.84
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Abstract
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Objectives
This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers.
Materials and Methods
For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering composite resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin.
Results
Color difference (ΔE*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at any thickness (ΔE* > 3.3).
Conclusion
When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for choosing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel.
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Citations
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- Improvement of mechanical strength and water repellency of Hanji (traditional Korean paper) through acetylation in supercritical CO2
Seungmok Shin, Hwi-Sung Lee, Hee Suk Woo, Mulugeta G. Aregay, Tae Jun Yoon, Youn-Woo Lee The Journal of Supercritical Fluids.2022; 190: 105735. CrossRef - Color Change in Tooth Induced by Various Calcium Silicate-Based Pulp-Capping Materials
Jiyoon Jeon, Namki Choi, Seonmi Kim THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY.2021; 48(3): 280. CrossRef
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Bonding efficacy of cured or uncured dentin adhesives in indirect resin
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Ji-Hyun Jang, Bin-Na Lee, Hoon-Sang Chang, Yun-Chan Hwang, Won-Mann Oh, In-Nam Hwang
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J Korean Acad Conserv Dent 2011;36(6):490-497. Published online November 30, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.6.490
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Abstract
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Objectives
This study examined the effect of the uncured dentin adhesives on the bond interface between the resin inlay and dentin.
Materials and Methods
Dentin surface was exposed in 24 extracted human molars and the teeth were assigned to indirect and direct resin restoration group. For indirect resin groups, exposed dentin surfaces were temporized with provisional resin. The provisional restoration was removed after 1 wk and the teeth were divided further into 4 groups which used dentin adhesives (OptiBond FL, Kerr; One-Step, Bisco) with or without light-curing, respectively (Group OB-C, OB-NC, OS-C and OS-NC). Pre-fabricated resin blocks were cemented on the entire surfaces with resin cement. For the direct resin restoration groups, the dentin surfaces were treated with dentin adhesives (Group OB-D and OS-D), followed by restoring composite resin. After 24 hr, the teeth were assigned to microtensile bond strength (µTBS) and confocal laser scanning microscopy (CLSM), respectively.
Results
The indirect resin restoration groups showed a lower µTBS than the direct resin restoration groups. The µTBS values of the light cured dentin adhesive groups were higher than those of the uncured dentin adhesive groups (p < 0.05). CLSM analysis of the light cured dentin adhesive groups revealed definite and homogenous hybrid layers. However, the uncured dentin adhesive groups showed uncertain or even no hybrid layer.
Conclusions
Light-curing of the dentin adhesive prior to the application of the cementing material in luting a resin inlay to dentin resulted in definite, homogenous hybrid layer formation, which may improve the bond strength.
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Microtensile bond strength of resin inlay bonded to dentin treated with various temporary filling materials
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Tae-Woo Kim, Bin-Na Lee, Young-Jung Choi, So-Young Yang, Hoon-Sang Chang, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh
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J Korean Acad Conserv Dent 2011;36(5):419-424. Published online September 30, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.5.419
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Abstract
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Objectives
This study was aimed to determine the effects of temporary sealing materials on microtensile bond strength between resin-coated dentin and resin inlay and to compare the bonding effectiveness of delayed dentin sealing and that of immediate dentin sealing.
Materials and Methods
The teeth were divided into 4 groups: group 1, specimens were prepared using delayed dentin sealing after temporary sealing with zinc oxide eugenol (ZOE); group 2, specimens were prepared using immediate dentin sealing and ZOE sealing; group 3, specimens were prepared using immediate dentin sealing and Dycal (Dentsply) sealing; group 4, specimens were prepared using immediately sealed, and then temporarily sealed with a resin-based temporary sealing material.
After removing the temporary sealing material, we applied resin adhesive and light-cured. Then the resin inlays were applied and bonded to the cavity with a resin-based cement. The microtensile bond strength of the sectioned specimens were measured with a micro-tensile tester (Bisco Inc.). Significance between the specimen groups were tested by means of one-way ANOVA and multiple Duncan's test.
Results
Group 1 showed the lowest bond strength, and group 4 showed the highest bond strength (p < 0.01). When temporary sealing was performed with ZOE, immediate dentin sealing showed a higher bonding strength than delayed dentin sealing (p < 0.01).
Conclusions
Based on these results, immediate dentin sealing is more recommended than delayed dentin sealing in bonding a resin inlay to dentin. Also, resin-based temporary sealing materials have shown the best result.
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The effects of short-term application of calcium hydroxide on dentin fracture strength
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Eun-Jung Shin, Yeong-Joon Park, Bin-Na Lee, Ji-Hyun Jang, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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J Korean Acad Conserv Dent 2011;36(5):425-430. Published online September 30, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.5.425
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Abstract
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Objectives
This in vitro study investigated whether short-term application of calcium hydroxide in the root canal system for 1 and 4 wk affects the fracture strength of human permanent teeth.
Materials and Methods
Thirty two mature human single rooted mandibular premolars in similar size and dentin thickness without decay or restorations were hand and rotary instrumented and 16 teeth vertically packed with calcium hydroxide paste and sealed coronally with caviton to imitate the endodontic procedure and the other 16 teeth was left empty as a control group. The apicies of all the samples were sealed with resin, submerged in normal saline and put in a storage box at 37℃ to mimic the oral environment. After 1 and 4 wk, 8 samples out of 16 samples from each group were removed from the storage box and fracture strength test was performed. The maximum load required to fracture the samples was recorded and data were analysed statistically by the two way ANOVA test at 5% significance level.
Results
The mean fracture strengths of two groups after 1 wk and 4 wk were similar. The intracanal placement of calcium hydroxide weakened the fracture strength of teeth by 8.2% after 4 wk: an average of 39.23 MPa for no treatment group and 36.01 MPa for CH group. However there was no statistically significant difference between experimental groups and between time intervals.
Conclusions
These results suggest that short term calcium hydroxide application is available during endodontic treatment.
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Citations
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- Effect of Calcium Hydroxide as an Intracanal Medication on Dentine Fracture Resistance: A Systematic Review and Network Meta-Analysis
Chayanit Sunlakawit, Chitpol Chaimanakarn, Natchalee Srimaneekarn, Sittichoke Osiri Journal of Endodontics.2024; 50(12): 1714. CrossRef
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The evaluation of color and color difference according to the layering placement of Incisal shade composites on the body composites of the indirect resin restoration
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Su-Jung Park, Han-Young Lee, Myong-Yun Nah, Hoon-Sang Chang, Yun-Chan Hwang, Won-Mann Oh, In-Nam Hwang
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J Korean Acad Conserv Dent 2011;36(1):37-49. Published online January 14, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.1.37
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Abstract
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- Abstract
Objectives:
The aim of this study was to evaluate the surface color of indirect resin restoration according to the layering placement of different shade of incisal composite.
Materials and Methods:
In this study, CIE L*a*b* value of 16 Body composite of Tescera ATL (Bisco, Schaumburg IL, USA) was measured by spectrophotometer (NF999, Nippon Denshuku, Japan), and compared to CIE L*a*b* value of Vitapan shade guide. Nine shade Incisal composite of Tescera ATL were buildup to 1 mm thickness on Body composites inlay block, and CIE L*a*b* value was measured. Incisal composite was ground to 0.5 mm thickness and CIE L*a*b* value was re-measured. Color difference between Body composite and Incisal composites layered on Body composite was calculated as a function of thickness.
Results:
Color difference between corresponding shade of Tescera Body composite and Vitapan shade guide was from 6.88 to 12.80.
L* and b*value was decreased as layering thickness of Incisal composite on Body composite was increased. But, a* value did not show specific change tendency.
Conclusions:
Surface color difference between Body composites and Incisal composites layered on Body composite was increased as the layering thickness of Incisal composite increased (p < 0.05).
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Citations
Citations to this article as recorded by 
- Color stability of esthetic restorative materials after application of fluoride varnishes
Chul-Hoon Jang, Dong-Gil Jang, Bin-Na Lee, Hoon-Sang Chang, Yun-Chan Hwang, Won-Mann Oh, In-Nam Hwang Korean Journal of Dental Materials.2021; 48(3): 147. CrossRef - Color Change in Tooth Induced by Various Calcium Silicate-Based Pulp-Capping Materials
Jiyoon Jeon, Namki Choi, Seonmi Kim THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY.2021; 48(3): 280. CrossRef - Discrimination between FRC-post and core according to the color difference
Jou-Hwe Kim, Jin-Woo Kim, Kyung-Mo Cho, Se-Hee Park Journal of Dental Rehabilitation and Applied Science.2015; 31(2): 75. CrossRef - Optical characteristics of resin composite before and after polymerization
Ah-Hyang Eom, Duck-Su Kim, Soo-Hee Lee, Chang-Won Byun, Noh-Hoon Park, Kyoung-Kyu Choi Journal of Korean Academy of Conservative Dentistry.2011; 36(3): 219. CrossRef
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Power density of light curing units through resin inlays fabricated with direct and indirect composites
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Hoon-Sang Chang, Young-Jun Lim, Jeong-Mi Kim, Sung-Ok Hong
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J Korean Acad Conserv Dent 2010;35(5):353-358. Published online September 30, 2010
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DOI: https://doi.org/10.5395/JKACD.2010.35.5.353
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Abstract
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Objectives
The purpose of this study was to measure the power density of light curing units transmitted through resin inlays fabricated with direct composite (Filtek Z350, Filtek Supreme XT) and indirect composite (Sinfony).
Materials and Methods
A3 shade of Z350, A3B and A3E shades of Supreme XT, and A3, E3, and T1 shades of Sinfony were used to fabricate the resin inlays in 1.5 mm thickness. The power density of a halogen light curing unit (Optilux 360) and an LED light curing unit (Elipar S10) through the fabricated resin inlays was measured with a hand held dental radiometer (Cure Rite). To investigate the effect of each composite layer consisting the resin inlays on light transmission, resin specimens of each shade were fabricated in 0.5 mm thickness and power density was measured through the resin specimens.
Results
The power density through the resin inlays was lowest with the Z350 A3, followed by Supreme XT A3B and A3E. The power density was highest with Sinfony A3, E3, and T1 (p < 0.05). The power density through 0.5 mm thick resin specimens was lowest with dentin shades, Sinfony A3, Z350 A3, Supreme XT A3B, followed by enamel shades, Supreme XT A3E and Sinfony E3. The power density was highest with translucent shade, Sinfony T1 (p < 0.05).
Conclusions
Using indirect lab composites with dentin, enamel, and translucent shades rather than direct composites with one or two shades could be advantageous in transmitting curing lights through resin inlays.
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Citations
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- Comparison of polymerization shrinkage of dual-cure core build-up resin according to shade and curing mode
Yoorina Choi, Karl Lee, Hoon-Sang Chang Oral Biology Research.2019; 43(4): 243. CrossRef - Early Hardness and Shear Bond Strength of Dual-cure Resin Cement Light Cured Through Resin Overlays With Different Dentin-layer Thicknesses
H-S Chang, J-W Kim Operative Dentistry.2014; 39(4): 398. CrossRef - Effects of layering technique on the shade of resin overlays and the microhardness of dual cure resin cement
Hoon-Sang Chang, Sung-Ok Hong Brazilian Oral Research.2014;[Epub] CrossRef - Light curing of dual cure resin cement
Hoon-Sang Chang Restorative Dentistry & Endodontics.2013; 38(4): 266. CrossRef - Power density of various light curing units through resin inlays with modified layer thickness
Sung-Ok Hong, Yonghui Oh, Jeong-Bum Min, Jin-Woo Kim, Bin-Na Lee, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh, Hoon-Sang Chang Restorative Dentistry & Endodontics.2012; 37(3): 130. CrossRef
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Effect of infection control barrier thickness on light curing units
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Hoon-Sang Chang, Seok-Ryun Lee, Sung-Ok Hong, Hyun-Wook Ryu, Chang-Kyu Song, Kyung-San Min
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J Korean Acad Conserv Dent 2010;35(5):368-373. Published online September 30, 2010
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DOI: https://doi.org/10.5395/JKACD.2010.35.5.368
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Abstract
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Objectives
This study investigated the effect of infection control barrier thickness on power density, wavelength, and light diffusion of light curing units.
Materials and Methods
Infection control barrier (Cleanwrap) in one-fold, two-fold, four-fold, and eight-fold, and a halogen light curing unit (Optilux 360) and a light emitting diode (LED) light curing unit (Elipar FreeLight 2) were used in this study. Power density of light curing units with infection control barriers covering the fiberoptic bundle was measured with a hand held dental radiometer (Cure Rite). Wavelength of light curing units fixed on a custom made optical breadboard was measured with a portable spectroradiometer (CS-1000). Light diffusion of light curing units was photographed with DSLR (Nikon D70s) as above.
Results
Power density decreased significantly as the layer thickness of the infection control barrier increased, except the one-fold and two-fold in halogen light curing unit. Especially, when the barrier was four-fold and more in the halogen light curing unit, the decrease of power density was more prominent. The wavelength of light curing units was not affected by the barriers and almost no change was detected in the peak wavelength. Light diffusion of LED light curing unit was not affected by barriers, however, halogen light curing unit showed decrease in light diffusion angle when the barrier was four-fold and statistically different decrease when the barrier was eight-fold (p < 0.05).
Conclusions
It could be assumed that the infection control barriers should be used as two-fold rather than one-fold to prevent tearing of the barriers and subsequent cross contamination between the patients.
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Citations
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- Light curing infection control barriers: do some types jeopardize the concept of conventional bulk-fill composites?
Dalia I. Sherief, Mohamed M. Kandil, Dina Ahmed El-Refai BMC Oral Health.2024;[Epub] CrossRef - Effects of Infection Control Barriers on Light Output from a Dental Light-Curing Unit Used in Various Positions
Jitte van der Zee, Andrew Tawse-Smith, Sunyoung Ma Oral.2023; 3(2): 166. CrossRef - Evaluation of irradiance and spectral output of visible light curing units used in the laboratory
Yoorina Choi, Su-Beom Choi, Ji-Hye Jung, Hoon-Sang Chang Oral Biology Research.2021; 45(4): 201. CrossRef - The Effectiveness of Clinical Sterilization Methods in Dental Air/water Syringes
Seyoung Shin, Yeonmi Yang, Miah Kim, Jaegon Kim, Byeongju Baik THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY.2013; 40(4): 268. CrossRef - Power density of various light curing units through resin inlays with modified layer thickness
Sung-Ok Hong, Yonghui Oh, Jeong-Bum Min, Jin-Woo Kim, Bin-Na Lee, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh, Hoon-Sang Chang Restorative Dentistry & Endodontics.2012; 37(3): 130. CrossRef - Effect of a multi-layer infection control barrier on the micro-hardness of a composite resin
In-Nam Hwang, Sung-Ok Hong, Bin-Na Lee, Yun-Chan Hwang, Won-Mann Oh, Hoon-Sang Chang Journal of Applied Oral Science.2012; 20(5): 576. CrossRef
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Infection control of light curing units
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Hoon-Sang Chang
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J Korean Acad Conserv Dent 2010;35(4):235-237. Published online July 31, 2010
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DOI: https://doi.org/10.5395/JKACD.2010.35.4.235
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Abstract
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When curing the composite restorations with light curing units, the light guides are often in direct contact with oral tissues, therefore contamination of light guides is inevitable. Curing light guides fall into the "semicritical" instrument category according to the Centers for Disease Control and Prevention (CDC) and must be heat or vapor-sterilized or at a minimum, these semicritical instruments must be sterilized in a liquid chemical agent. Currently, most common methods of maintaining sterility of the light guides are wiping the guide with a disinfectant, such as glutaraldehyde, after each patient use; using autoclavable guides; using presterilized, single-use plastic guides; and using translucent disposable barriers to cover the guide.
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Citations
Citations to this article as recorded by 
- Effect of a multi-layer infection control barrier on the micro-hardness of a composite resin
In-Nam Hwang, Sung-Ok Hong, Bin-Na Lee, Yun-Chan Hwang, Won-Mann Oh, Hoon-Sang Chang Journal of Applied Oral Science.2012; 20(5): 576. CrossRef - Power density of various light curing units through resin inlays with modified layer thickness
Sung-Ok Hong, Yonghui Oh, Jeong-Bum Min, Jin-Woo Kim, Bin-Na Lee, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh, Hoon-Sang Chang Restorative Dentistry & Endodontics.2012; 37(3): 130. CrossRef
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Clinical diagnosis of herpes zoster presenting as odontogenic pain
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Seong-Hak Yang, Dong-Ho Jung, Hae-Doo Lee, Yoon Lee, Hoon-Sang Chang, Kyung-San Min
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J Korean Acad Conserv Dent 2008;33(5):452-456. Published online September 30, 2008
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DOI: https://doi.org/10.5395/JKACD.2008.33.5.452
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Abstract
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Herpes zoster, an acute viral infection produced by the varicella zoster virus, may affect any of the trigeminal branches. This case report presents a patient with symptoms mimicking odontogenic pain. No obvious cause of the symptoms could be found based on clinical and radiographic examinations. After a dermatologist made a diagnosis of herpes zoster involving the third trigeminal branch, the patient was given antiviral therapy. Two months later, the facial lesions and pain had almost disappeared, and residual pigmented scars were present. During the diagnostic process, clinicians should keep in mind the possibility that orofacial pain might be related to herpes zoster.
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Citations
Citations to this article as recorded by 
- Herpes Zoster Accompanying Odontogenic Inflammation: A Case Report with Literature Review
Soyeon Lee, Minsik Kim, Jong-Ki Huh, Jae-Young Kim Journal of Oral Medicine and Pain.2021; 46(1): 9. CrossRef - Recurrent Herpetic Stomatitis Mimicking Post-Root Resection Complication
Sung-Ok Hong, Jae-Kwan Lee, Hoon-Sang Chang Journal of Dental Rehabilitation and Applied Science.2013; 29(4): 418. CrossRef - Diagnostic challenges of nonodontogenic toothache
Hyung-Ok Park, Jung-Hong Ha, Myoung-Uk Jin, Young-Kyung Kim, Sung-Kyo Kim Restorative Dentistry & Endodontics.2012; 37(3): 170. CrossRef
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Microleakage of endodontic temporary restorative materials under dynamic loading
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Dong-Ho Jung, Young-Sin Noh, Hae-Doo Lee, Hoon-Sang Chang, Hyun-Wook Ryu, Kyung-San Min
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J Korean Acad Conserv Dent 2008;33(3):198-203. Published online May 31, 2008
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DOI: https://doi.org/10.5395/JKACD.2008.33.3.198
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Abstract
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The purpose of this study was to compare the sealing abilities of four endodontic temporary restorative materials using a methylene blue dye penetration test under dynamic loading. Standardized access cavities were prepared in forty-four intact human permanent molar teeth, and the cavities were restored with Caviton, MD-Temp, IRM, or ZOE. After thermocycling, an intermittent load of 98 N at 1 Hz was applied for 1,000 cycles to the long axis of the functional cusp of each of the teeth, which were immersed in a 1% methylene blue solution. The teeth were split in half, and the linear depth of dye penetration was evaluated according to the criteria. The results were analyzed using one-way ANOVA (p = 0.05) and Duncan's multiple range test. The results demonstrated that Caviton and MD-Temp showed significantly lower microleakage than IRM and ZOE. It was concluded that Caviton and MD-Temp exhibited better sealing ability than IRM and ZOE under dynamic loading.
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Citations
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- Coronal microleakage of four temporary restorative materials in Class II-type endodontic access preparations
Sang-Mi Yun, Lorena Karanxha, Hee-Jin Kim, Sung-Ho Jung, Su-Jung Park, Kyung-San Min Restorative Dentistry & Endodontics.2012; 37(1): 29. CrossRef
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The palato-gingival groove - anatomical anomaly occurred in maxillary lateral incisors: case reports
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Hyun-Il Kim, Young-Shin Noh, Hoon-Sang Chang, Hyun-Wook Ryu, Kyung-San Min
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J Korean Acad Conserv Dent 2007;32(6):483-490. Published online November 30, 2007
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DOI: https://doi.org/10.5395/JKACD.2007.32.6.483
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Abstract
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This report describes clinical cases of a palato-gingival groove on a maxillary lateral incisor with associated localized periodontal disease and pulp necrosis. The tooth of the first case was extracted because of severe bone destruction. The palato-gingival groove of the second case was eliminated using a round bur, and the resulting defect was filled with synthetic graft and covered by an absorbable membrane. Both diagnosis and treatment of palato-gingival groove were very difficult and usually extraction of the involved tooth is the treatment of choice, but combined endodontic-periodontic treatment allowed the tooth to be saved.
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Citations
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- Radicular lingual groove: A contributory factor in periodontal pathology
Gaurav Didhra, Jagjit Singh, Rajan Gupta, Parveen Dahiya Archives of Medicine and Health Sciences.2019; 7(2): 240. CrossRef - Management of a Palatal Gingival Groove in a Maxillary Lateral Incisor: A Case Report
Ashkan Salari, Maosumeh Faramarzi, Seyedeh Fereshteh Naser alavi Journal of Periodontology & Implant Dentistry.2016; 7(2): 66. CrossRef - Endodontic treatment of maxillary lateral incisors with anatomical variations
Moon-Hwan Lee, Jung-Hong Ha, Myoung-Uk Jin, Young-Kyung Kim, Sung-Kyo Kim Restorative Dentistry & Endodontics.2013; 38(4): 253. CrossRef
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Evaluation of the radiopacity and cytotoxicity of resinous root canal sealers
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Chang-Kyu Kim, Hyun-Wook Ryu, Hoon-Sang Chang, Byung-Do Lee, Kyung-San Min, Chan-Ui Hong
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J Korean Acad Conserv Dent 2007;32(5):419-425. Published online September 30, 2007
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DOI: https://doi.org/10.5395/JKACD.2007.32.5.419
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Abstract
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The aim of this study was to evaluate the radiopacity and cytotoxicity of three resin-based (AH 26, EZ fill and AD Seal), a zinc oxide-eugenol-based (ZOB Seal), and a calcium hydroxide-based (Sealapex) root canal sealers. Specimens, 10 mm in diameter and 1 mm in thickness, were radiographed simultaneously with an aluminum step wedge using occlusal films, according to ISO 6876/2001 standards. Radiographs were digitized, and the radiopacity of sealers was compared to the different thicknesses of the aluminum step wedge, using the Scion image software. Using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, the cytotoxicity of each material was determined in immortalized human periodontal ligament (IPDL) cells.
The results demonstrated that EZ fill was the most radiopaque sealer, while Sealapex was the least radiopaque (p < 0.05). AH 26, AD Seal and ZOB Seal presented intermediate radiopacity values. All the materials evaluated, except for Sealapex, presented the minimum radiopacity required by ISO standards. The cell viabilities of resin-based root canal sealers were statistically higher than that of other type of root canal sealers through the all experimental time. Further, EZ fill showed statistically lower cell viability in 24 and 48 hours compared to AD Seal and in 72 hours compared to all other resin-based root canal sealers. However, there was no correlation between the radiopacity and cytotoxicity of three resin-based root canals sealers (p > 0.05).
These results indicate that resin-based root canal sealer is more biocompatible and has advantage in terms of radiopacity.
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- A Comparative Evaluation of Two Commonly Used GP Solvents on Different Epoxy Resin-based Sealers: An In Vitro Study
Sakshi Tyagi, Ekta Choudhary, Rajat Chauhan, Ashish Choudhary International Journal of Clinical Pediatric Dentistry.2020; 13(1): 35. CrossRef - Evaluation of softening ability of Xylene & Endosolv-R on three different epoxy resin based sealers within 1 to 2 minutes - anin vitrostudy
Pratima Ramakrishna Shenoi, Gautam Pyarelal Badole, Rajiv Tarachand Khode Restorative Dentistry & Endodontics.2014; 39(1): 17. CrossRef - A comparative evaluation of cytotoxicity of root canal sealers: anin vitrostudy
Gautam Pyarelal Badole, Manjusha Madhukar Warhadpande, Ganesh Kothiramji Meshram, Rakesh Namdeoraoji Bahadure, Shubha Gopal Tawani, Gopal Tawani, Shital Gautam Badole Restorative Dentistry & Endodontics.2013; 38(4): 204. CrossRef - Evaluation of radiopacity and discriminability of various fiber reinforced composite posts
Eun-Hye Lee, Hang-Moon Choi, Se-Hee Park, Jin-Woo Kim, Kyung-Mo Cho Journal of Korean Academy of Conservative Dentistry.2010; 35(3): 188. CrossRef - A comparative study on radiopacity of root canal sealers
Tae-Min Kim, Seo-Kyoung Kim, In-Nam Hwang, Yun-Chan Hwang, Byung-Cheol Kang, Suk-Ja Yoon, Jae-Seo Lee, Won-Mann Oh Journal of Korean Academy of Conservative Dentistry.2009; 34(1): 61. CrossRef - A comparative study on radiopacity of canal filling and retrograde root-end filling materials
Yong-Sang Kim, Seo-Kyong Kim, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh Journal of Korean Academy of Conservative Dentistry.2008; 33(2): 107. CrossRef
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The instrument-centering ability of four Nickel-Titanium instruments in simulated curved root canals
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Jae-Hoon Ku, Hoon-Sang Chang, Seok-Woo Chang, Hwan-Hee Cho, Ji-Myung Bae, Kyung-San Min
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J Korean Acad Conserv Dent 2006;31(2):113-118. Published online March 31, 2006
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DOI: https://doi.org/10.5395/JKACD.2006.31.2.113
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Abstract
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The aim of this study was to evaluate the ability of newly marketed NRT instruments to maintain the original root canal configuration and curvature during preparation in comparison with the three existing instruments in simulated root canals.
Simulated canals in resin blocks were prepared with ProFile, K3, ProTaper, and NRT instrument (n = 10 canals in each case). Pre- and post-operative images were recorded, and assessment of canal shape was completed with a computer image analysis program. The data were analyzed statistically using the One-way ANOVA followed by Duncan's test.
The ability of instruments to remain centered in prepared canals at 1-, 2-mm levels was significantly better in ProFile groups than in other groups (p < 0.05). The change of centering ratio in NRT groups at 5-mm level was significantly greater than ProFile group and at 6- and 7-mm level than all other groups (p < 0.05).
Although the NRT system was comparable to other systems in regards to its ability to maintain the canal configuration of apical portion, this system was more influenced by the mid-root curvature due to its stainless-steel files for coronal preflaring.
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Citations
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- A comparison of the shaping ability of reciprocating NiTi instruments in simulated curved canals
Young-Sil Yoo, Yong-Bum Cho Restorative Dentistry & Endodontics.2012; 37(4): 220. CrossRef - Effect of cross-sectional area of 6 nickel-titanium rotary instruments on the fatigue fracture under cyclic flexural stress: A fractographic analysis
Soo-Youn Hwang, So-Ram Oh, Yoon Lee, Sang-Min Lim, Kee-Yeon Kum Journal of Korean Academy of Conservative Dentistry.2009; 34(5): 424. CrossRef
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