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Review Article
Influence of disinfecting solutions on the surface topography of gutta-percha cones: a systematic review of in vitro studies
Lora Mishra, Gathani Dash, Naomi Ranjan Singh, Manoj Kumar, Saurav Panda, Franck Diemer, Monika Lukomska-Szymanska, Barbara Lapinska, Abdul Samad Khan
Restor Dent Endod 2024;49(4):e42.   Published online November 1, 2024
DOI: https://doi.org/10.5395/rde.2024.49.e42
AbstractAbstract PDFSupplementary MaterialPubReaderePub

The surface integrity of gutta-percha cones is a crucial factor in the success of endodontic procedures. Disinfecting solutions play a pivotal role in sterilizing gutta-percha cones, but their influence on gutta-percha surface topography remains a subject of concern. This systematic review aimed to present a qualitative synthesis of available laboratory studies assessing the influence of disinfecting solutions on the surface topography of gutta-percha and offers insights into the implications for clinical practice. The present review followed PRISMA 2020 guidelines. An advanced database search was performed in PubMed, Google Scholar, Embase, Scopus, LILAC, non-indexed citations and reference lists of eligible studies in May 2024. Laboratory studies, in English language, were considered for inclusion. The quality (risk of bias) of the included studies was assessed using parameters for in vitro studies. A total of 28 studies were included in the qualitative synthesis. Based on the included in vitro studies, surface deposits and alterations in the physical properties of gutta-percha cones were observed after the disinfection protocol. A comprehensive review of the available literature indicates that the choice of disinfecting solution, its concentration, and immersion time significantly affect the surface topography of gutta-percha cones.

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Research Articles
Fracture resistance after root canal filling removal using ProTaper Next, ProTaper Universal Retreatment or hybrid instrumentation: an ex vivo study
Hadeel Hassan Hanafy, Marwa Mahmoud Bedier, Suzan Abdul Wanees Amin
Restor Dent Endod 2024;49(4):e38.   Published online October 11, 2024
DOI: https://doi.org/10.5395/rde.2024.49.e38
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated the effect of ProTaper Next (PTN), ProTaper Universal Retreatment (PTR) and hybrid instrumentation (HI) for canal filling removal on the fracture resistance (FR), mode of failure (MoF), and filling removal time.

Materials and Methods

Ninety-six, mandibular premolars were decoronated and randomly divided into 6 groups (n = 16), as follows: sound (S), untreated canals; prepared teeth (P), canals only prepared to ProTaper Universal finishing instrument (F4); endodontically-treated (ET), prepared and obturated canals using the single-cone technique; and groups PTN, PTR, and HI where filling was removed using PTN, PTR, or HI respectively. FR under vertical loading; MoF and time were assessed. Data were analyzed (Significance level [α] = 0.05).

Results

There was a significant difference in FR among all groups (p < 0.001) (HI < P < PTN < S < ET < PTR). HI showed lower FR than S, ET and PTR, and P showed lower FR than PTR (p < 0.05). For experimental groups, there was a significant difference between every group pair (p < 0.05) No significant difference was found regarding MoF distribution (p > 0.05). HI required the highest filling removal time, while PTR required the least (p < 0.05 between every group pair).

Conclusions

The effect of filling removal on FR may depend on the filling removal technique/system used. PTR could be faster and protect against fracture followed by PTN; HI could adversely affect FR. FR may be associated with filling removal time.

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Comparison of shaping ability of the Reciproc Blue and One Curve with or without glide path in simulated S-shaped root canals
Vincenzo Biasillo, Raffaella Castagnola, Mauro Colangeli, Claudia Panzetta, Irene Minciacchi, Gianluca Plotino, Simone Staffoli, Luca Marigo, Nicola Maria Grande
Restor Dent Endod 2022;47(1):e3.   Published online December 28, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e3
AbstractAbstract PDFPubReaderePub
Objectives

This study aimed to assess the impact of a glide-path on the shaping ability of 2 single-file instruments and to compare the centering ability, maintenance of original canal curvatures and area of instrumentation in simulated S-shaped root canals.

Materials and Methods

Forty simulated S-shaped root canals were used and were prepared with One Curve (group OC), One G and OC (group GOC), Reciproc Blue (group RB) and R-Pilot and RB (group PRB) and scanned before and after instrumentation. The images were analyzed using AutoCAD. After superimposing the samples, 4 levels (D1, D2, D3, and D4) and 2 angles (Δ1 and Δ2) were established to evaluate the centering ability and modification of the canal curvatures. Then, the area of instrumentation (ΔA) was measured. The data were analyzed using 2-way analysis of variance and Tukey's test for multiple comparisons (p < 0.05).

Results

Regarding the centering ability in the apical part (D3, D4), the use of the glide-path yielded better results than the single-file groups. Among the groups at D4, OC showed the worst results (p < 0.05). The OC system removed less material (ΔA) than the RB system, and for Δ1, OC yielded a worse result than RB (p < 0.05).

Conclusions

The glide-path improved the centering ability in the apical part of the simulated S-shaped canals. The RB system showed a better centering ability in the apical part and major respect of the canal curvatures compared with OC system.

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Effect of intracanal cryotherapy on postoperative pain after endodontic treatment: systematic review with meta-analysis
Fernanda Garcias Hespanhol, Ludmila Silva Guimarães, Lívia Azeredo Alves Antunes, Leonardo Santos Antunes
Restor Dent Endod 2022;47(3):e30.   Published online July 4, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e30
AbstractAbstract PDFPubReaderePub
Objectives

This study aimed to evaluate the effectiveness of final irrigation with cold saline solution after endodontic treatment compared with saline solution at room temperature against postoperative pain following endodontic treatment.

Materials and Methods

A broad search was performed in the PubMed, Web of Science, Scopus, Cochrane Library, Virtual Health Library (LILACS), and Grey Literature databases. Two independent reviewers performed data extraction, risk of bias using the Cochrane methodology, and certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach.

Results

Eight studies were included in qualitative synthesis. Intracanal cryotherapy favored the reduction of postoperative pain in the systematic review. Four studies were included in meta-analyses. The meta-analysis showed that intracanal cryotherapy reduced postoperative pain in teeth with symptomatic apical periodontitis (SAP) at 24 hours. There was no association between intracanal cryotherapy and control (room temperature) groups in teeth with normal periapical tissue with respect to postoperative pain at 24 hours and 48 hours.

Conclusions

Intracanal cryotherapy was effective in reducing postoperative pain after endodontic treatment in teeth with SAP.

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Combination of a new ultrasonic tip with rotary systems for the preparation of flattened root canals
Karina Ines Medina Carita Tavares, Jáder Camilo Pinto, Airton Oliveira Santos-Junior, Fernanda Ferrari Esteves Torres, Juliane Maria Guerreiro-Tanomaru, Mario Tanomaru-Filho
Restor Dent Endod 2021;46(4):e56.   Published online October 27, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e56
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated 2 nickel-titanium rotary systems and a complementary protocol with an ultrasonic tip and a small-diameter instrument in flattened root canals.

Materials and Methods

Thirty-two human maxillary second premolars with flattened canals (buccolingual diameter ≥4 times larger than the mesiodistal diameter) at 9 mm from the radiographic apex were selected. The root canals were prepared by ProDesign Logic (PDL) 30/0.01 and 30/0.05 or Hyflex EDM (HEDM) 10/0.05 and 25/0.08 (n = 16), followed by application of the Flatsonic ultrasonic tip in the cervical and middle thirds and a PDL 25/0.03 file in the apical third (FPDL). The teeth were scanned using micro-computed tomography before and after the procedures. The percentage of volume increase, debris, and uninstrumented surface area were analyzed using the Kruskal-Wallis, Dunn, Wilcoxon, analysis of variance/Tukey, and paired and unpaired t-tests (α = 0.05).

Results

No significant difference was found in the volume increase and uninstrumented surface area between PDL and HEDM (p > 0.05). PDL had a higher percentage of debris than HEDM in the middle and apical thirds (p < 0.05). The FPDL protocol resulted in less debris and uninstrumented surface area for PDL and HEDM (p < 0.05). This protocol, with HEDM, reduced debris in the middle and apical thirds and uninstrumented surface area in the apical third (p < 0.05).

Conclusions

High percentages of debris and uninstrumented surface area were observed after preparation of flattened root canals. The HEDM, Flatsonic tip, and 25/0.03 instrument protocol enhanced cleaning in flattened root canals.

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Shaping ability and apical debris extrusion after root canal preparation with rotary or reciprocating instruments: a micro-CT study
Emmanuel João Nogueira Leal da Silva, Sara Gomes de Moura, Carolina Oliveira de Lima, Ana Flávia Almeida Barbosa, Waleska Florentino Misael, Mariane Floriano Lopes Santos Lacerda, Luciana Moura Sassone
Restor Dent Endod 2021;46(2):e16.   Published online February 25, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e16
AbstractAbstract PDFPubReaderePub
Objectives

The aim of this study was to evaluate the shaping ability of the TruShape and Reciproc Blue systems and the apical extrusion of debris after root canal instrumentation. The ProTaper Universal system was used as a reference for comparison.

Materials and Methods

Thirty-three mandibular premolars with a single canal were scanned using micro-computed tomography and were matched into 3 groups (n = 11) according to the instrumentation system: TruShape, Reciproc Blue and ProTaper Universal. The teeth were accessed and mounted in an apparatus with agarose gel, which simulated apical resistance provided by the periapical tissue and enabled the collection of apically extruded debris. During root canal preparation, 2.5% sodium hypochlorite was used as an irrigant. The samples were scanned again after instrumentation. The percentage of unprepared area, removed dentin, and volume of apically extruded debris were analyzed. The data were analyzed using 1-way analysis of variance and the Tukey test for multiple comparisons at a 5% significance level.

Results

No significant differences in the percentage of unprepared area were observed among the systems (p > 0.05). ProTaper Universal presented a higher percentage of dentin removal than the TruShape and Reciproc Blue systems (p < 0.05). The systems produced similar volumes of apically extruded debris (p > 0.05).

Conclusions

All systems caused apically extruded debris, without any significant differences among them. TruShape, Reciproc Blue, and ProTaper Universal presented similar percentages of unprepared area after root canal instrumentation; however, ProTaper Universal was associated with higher dentin removal than the other systems.

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YouTube as an information source for instrument separation in root canal treatment
Yağız Özbay, Neslihan Yılmaz Çırakoğlu
Restor Dent Endod 2021;46(1):e8.   Published online January 12, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e8
AbstractAbstract PDFPubReaderePub
Objectives

The reliability and educational quality of videos on YouTube for patients seeking information regarding instrument separation in root canal treatment were evaluated.

Materials and Methods

YouTube was searched for videos on instrument separation in root canal treatment. Video content was scored based on reliability in terms of 3 categories (etiology, procedure, and prognosis) and based on video flow, quality, and educational usefulness using the Global Quality Score (GQS). Descriptive statistics were obtained and the data were analyzed using analysis of variance and the Kruskal-Wallis test.

Results

The highest mean completeness scores were obtained for videos published by dentists or specialists (1.48 ± 1.06). There was no statistically significant difference among sources of upload in terms of content completeness. The highest mean GQS was found for videos published by dentists or specialists (1.82 ± 0.96), although there was no statistically significant correlation between GQS and the source of upload.

Conclusions

Videos on YouTube have incomplete and low-quality content for patients who are concerned about instrument separation during endodontic treatment, or who experience this complication during endodontic treatment.

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Micro-computed tomographic assessment of the shaping ability of the One Curve, One Shape, and ProTaper Next nickel-titanium rotary systems
Pelin Tufenkci, Kaan Orhan, Berkan Celikten, Burak Bilecenoglu, Gurkan Gur, Semra Sevimay
Restor Dent Endod 2020;45(3):e30.   Published online May 22, 2020
DOI: https://doi.org/10.5395/rde.2020.45.e30
AbstractAbstract PDFPubReaderePub
Objectives

This micro-computed tomographic (CT) study aimed to compare the shaping abilities of ProTaper Next (PTN), One Shape (OS), and One Curve (OC) files in 3-dimensionally (3D)-printed mandibular molars.

Materials and Methods

In order to ensure standardization, 3D-printed mandibular molars with a consistent mesiobuccal canal curvature (45°) were used in the present study (n = 18). Specimens were instrumented with the OC, OS, or PTN files. The teeth were scanned pre- and post-instrumentation using micro-CT to detect changes of the canal volume and surface area, as well as to quantify transportation of the canals after instrumentation. Two-way analysis of variance was used for statistical comparisons.

Results

No statistically significant differences were found between the OC and OS groups in the changes of the canal volume and surface area before and after instrumentation (p > 0.05). The OC files showed significantly less transportation than the OS or PTN systems for the apical section (p < 0.05). In a comparison of the systems, similar values were found at the coronal and middle levels, without any significant differences (p > 0.05).

Conclusions

These 3 instrumentation systems showed similar shaping abilities, although the OC file achieved a lesser extent of transportation in the apical zone than the OS and PTN files. All 3 file systems were confirmed to be safe for use in mandibular mesial canals.

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The top 10 most-cited articles on the management of fractured instruments: a bibliometric analysis
Lora Mishra, Hyeon-Cheol Kim, Naomi Ranjan Singh, Priti Pragati Rath
Restor Dent Endod 2019;44(1):e2.   Published online December 26, 2018
DOI: https://doi.org/10.5395/rde.2019.44.e2
AbstractAbstract PDFPubReaderePub
Objectives

The purpose of this research was to identify the top 10 most-cited articles on the management of fractured or broken instruments and to perform a bibliometric analysis thereof.

Materials and Methods

Published articles related to fractured instruments were screened from online databases, such as Web of Science, Scopus, PubMed, and ScienceDirect, and highly cited papers, with at least 50 citations since publication, were identified. The most-cited articles were selected and analysed with regard to publication title, authorship, the journal of publication, year, institution, country of origin, article type, and number of citations.

Results

The top 10 most-cited articles were from various journals. Most were published in the Journal of Endodontics, followed by the International Endodontic Journal, and Dental Traumatology. The leading countries were Australia, Israel, Switzerland, the USA, and Germany, and the leading institution was the University of Melbourne. The majority of articles among the top 10 articles were clinical research studies (n = 8), followed by a basic research article and a non-systematic review article.

Conclusions

This bibliometric analysis revealed interesting information about scientific progress in endodontics regarding fractured instruments. Overall, clinical research studies and basic research articles published in high-impact endodontic journals had the highest citation rates.

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Incidence of apical crack formation and propagation during removal of root canal filling materials with different engine driven nickel-titanium instruments
Taha Özyürek, Vildan Tek, Koray Yılmaz, Gülşah Uslu
Restor Dent Endod 2017;42(4):332-341.   Published online November 4, 2017
DOI: https://doi.org/10.5395/rde.2017.42.4.332
AbstractAbstract PDFPubReaderePub
Objectives

To determine the incidence of crack formation and propagation in apical root dentin after retreatment procedures performed using ProTaper Universal Retreatment (PTR), Mtwo-R, ProTaper Next (PTN), and Twisted File Adaptive (TFA) systems.

Materials and Methods

The study consisted of 120 extracted mandibular premolars. One millimeter from the apex of each tooth was ground perpendicular to the long axis of the tooth, and the apical surface was polished. Twenty teeth served as the negative control group. One hundred teeth were prepared, obturated, and then divided into 5 retreatment groups. The retreatment procedures were performed using the following files: PTR, Mtwo-R, PTN, TFA, and hand files. After filling material removal, apical enlargement was done using apical size 0.50 mm ProTaper Universal (PTU), Mtwo, PTN, TFA, and hand files. Digital images of the apical root surfaces were recorded before preparation, after preparation, after obturation, after filling removal, and after apical enlargement using a stereomicroscope. The images were then inspected for the presence of new apical cracks and crack propagation. Data were analyzed with χ2 tests using SPSS 21.0 software.

Results

New cracks and crack propagation occurred in all the experimental groups during the retreatment process. Nickel-titanium rotary file systems caused significantly more apical crack formation and propagation than the hand files. The PTU system caused significantly more apical cracks than the other groups after the apical enlargement stage.

Conclusions

This study showed that retreatment procedures and apical enlargement after the use of retreatment files can cause crack formation and propagation in apical dentin.

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Post space preparation timing of root canals sealed with AH Plus sealer
Hae-Ri Kim, Young Kyung Kim, Tae-Yub Kwon
Restor Dent Endod 2017;42(1):27-33.   Published online December 19, 2016
DOI: https://doi.org/10.5395/rde.2017.42.1.27
AbstractAbstract PDFPubReaderePub
Objectives

To determine the optimal timing for post space preparation of root canals sealed with epoxy resin-based AH Plus sealer in terms of its polymerization and influence on apical leakage.

Materials and Methods

The epoxy polymerization of AH Plus (Dentsply DeTrey) as a function of time after mixing (8, 24, and 72 hours, and 1 week) was evaluated using Fourier transform infrared (FTIR) spectroscopy and microhardness measurements. The change in the glass transition temperature (Tg) of the material with time was also investigated using differential scanning calorimetry (DSC). Fifty extracted human single-rooted premolars were filled with gutta-percha and AH Plus, and randomly separated into five groups (n = 10) based on post space preparation timing (immediately after root canal obturation and 8, 24, and 72 hours, and 1 week after root canal obturation). The extent of apical leakage (mm) of the five groups was compared using a dye leakage test. Each dataset was statistically analyzed by one-way analysis of variance and Tukey's post hoc test (α = 0.05).

Results

Continuous epoxy polymerization of the material with time was observed. Although the Tg values of the material gradually increased with time, the specimens presented no clear Tg value at 1 week after mixing. When the post space was prepared 1 week after root canal obturation, the leakage was significantly higher than in the other groups (p < 0.05), among which there was no significant difference in leakage.

Conclusions

Poor apical seal was detected when post space preparation was delayed until 1 week after root canal obturation.

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Original Articles
Shaping ability of four rotary nickel-titanium instruments to prepare root canal at danger zone
Seok-Dong Choi, Myoung-Uk Jin, Ki-Ok Kim, Sung-Kyo Kim
J Korean Acad Conserv Dent 2004;29(5):446-453.   Published online September 30, 2004
DOI: https://doi.org/10.5395/JKACD.2004.29.5.446
AbstractAbstract PDFPubReaderePub

The aim of this study was to evaluate the shaping abilities of four different rotary nickel-titanium instruments with anticurvature motion to prepare root canal at danger zone by measuring the change of dentin thickness in order to have techniques of safe preparation of canals with nickel-titanium files.

Mesiobuccal and mesiolingual canals of forty mesial roots of extracted human lower molars were instrumented using the crown-down technique with ProFile, GT™ Rotary file, Quantec file and ProTaper™. In each root, one canal was prepared with a straight up-and-down motion and the other canal was with an anticurvature motion. Canals were instrumented until apical foramens were up to size of 30 by one operator. The muffle system was used to evaluate the root canal preparation. After superimposing the pre- and post-instrumentation canal, change in root dentin thickness was measured at the inner and outer sides of the canal at 1, 3, and 5 mm levels from the furcation. Data were analyzed using two-way ANOVA.

Root dentin thickness at danger zone was significantly thinner than that at safe zone at all levels (p < 0.05).

There was no significant difference in the change of root dentin thickness between the straight up-and-down and the anticurvature motions at both danger and safe zones in all groups (p > 0.05).

ProTaper removed significantly more dentin than other files especially at furcal 3 mm level of danger and safe zones (p < 0.05)

Therefore, it was concluded that anticurvature motion with nickel-titanium rotary instruments does not seem to be effective in danger zone of lower molars.

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Evaluation of canal preparation with Ni-Ti rotary files by micro computed tomography
Jeong-Ho Lee, Mi-Ja Kim, Chang-In Seok, Woo-Cheol Lee, Seung-Ho Baek
J Korean Acad Conserv Dent 2004;29(4):378-385.   Published online July 31, 2004
DOI: https://doi.org/10.5395/JKACD.2004.29.4.378
AbstractAbstract PDFPubReaderePub

The purpose of this study was to compare the effects of preparation with GT files and profiles .04 in shaping of root canals and reconstruct the three-dimensional root canal system using micro computed tomography.

40 canals of the extracted human mandibular molars were used, and randomly distributed into two experimental groups. In group 1, canals were prepared by GT files. In group 2, Profiles .04. were used. Apical preparation size was #30.

For each tooth pre and post operative cross-sectional images were obtained by the micro CT at 50 micron intervals. Pre and post operative cross-sectional images of 1, 2, 3, 5, and 8mm from the apex were compared. For each section, canal area and centering ratio were determined. For each tooth pre- and post-operative root canal volume from the furcation to the apex of the roots was calculated by three-dimensional image software. Following results were obtained:

1. At 8mm from the apex, area of dentin removed by GT rotary file was significantly larger than that by Profile .04. And at the other levels there was not a significant difference.

2. There was a trend for GT rotary file to remain more centered in the canals than Profile .04 at all levels. But at 3mm level, there was a statistically significant difference.

3. In root canal volume increments after instrumentation, there was no significant difference between two groups.

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A sem observation on the efficiency preparation of oval canals using hand and engine-driven instruments
Uk Song, Bock Hur, Hee-Joo Lee
J Korean Acad Conserv Dent 2004;29(2):141-146.   Published online March 31, 2004
DOI: https://doi.org/10.5395/JKACD.2004.29.2.141
AbstractAbstract PDFPubReaderePub

The purpose of this study was to evaluate the efficiency of the preparation of oval canals using hand and engine-driven instruments with SEM observation. Thirty single-rooted teeth with oval canal were used in this study. The teeth were divided into 3 groups. In group A, the teeth were instrumented up to a size 35 K-file using RC-prep and irrigated with 5% NaOCl between each file size. In group B, the teeth were instrumented with Profile according to the manufacture's instructions using RC-Prep and irrigated with 5% NaOCl between each file size. In group C, the teeth were instrumented with GT file according to the manufacture's instructions using RC-prep and irrigated with 5% NaOCl between each file size. Then, in all teeth, a final flush of 5ml of distilled water delivered for 30s. Canals were dried with sterile standardized paper points. After preparing the canals, the teeth were sectioned along their mesial and diatal surfaces by using low-speed diamond disc, chisel and mallet. Each root section was then dehydrated in graded concentration of alcohol (70, 80, 90, 100%), mounted on an aluminum stub, sputter-coated with gold-palladium and observed with scanning electron microscope (HITACHI S-4200) in middle and apical area.

The results of this study were as follows:

In the middle area, group B and group C showed less smear layer than group A, and it was statistically significant (p < 0.05).

In the middle area, group B showed greater smear layer than group C, but it was not statistically significant (p > 0.05).

In the apical area, group C showed less smear layer than group A, and it was statistically significant (p < 0.05).

In the apical area, group A showed greater smear layer than group B, but it was not statistically significant (p > 0.05).

In the apical area, group B showed greater smear layer than group C, but it was not statistically significant (p > 0.05).

In all groups, the middle area was less smear layer than the apical area, and it was statistically significant (p < 0.05).

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