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Review Article
Success rate of direct pulp capping on permanent teeth using bioactive materials: a systematic review and meta-analysis of randomized clinical trials
Karem Paula Pinto, Gabriela Ribeiro da Silva, Cláudio Malizia Alves Ferreira, Luciana Moura Sassone, Emmanuel João Nogueira Leal da Silva
Restor Dent Endod 2024;49(4):e34.   Published online September 6, 2024
DOI: https://doi.org/10.5395/rde.2024.49.e34
AbstractAbstract PDFSupplementary MaterialPubReaderePub

This systematic review and meta-analysis aimed to evaluate the success rate of direct pulp capping (DPC) on permanent teeth, comparing the use of MTA with calcium hydroxide and calcium silicate-based cements. A systematic search was carried out in 4 databases until July 2023. The selection was based on PICOS criteria and only randomized clinical trials were included. The risk of bias was assessed using RoB-2 tool, and meta-analyses were performed using RevMan 5.3 software. The overall quality of evidence was determined using the GRADE tool. Thirteen studies were included. Meta-analyses indicated significantly higher success rate for DPC using MTA compared to calcium hydroxide, while no significant difference was observed between MTA and Biodentine, showing a success rate from 80% to 100% even after 3 years of follow-up. Five studies were classified as having high risk of bias and the GRADE assessment revealed low certainty of evidence. DPC is highly effective for permanent teeth when using MTA or Biodentine. There is a need for future well-designed randomized clinical trials to evaluate the efficacy of DPC using newer bioceramic materials.

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Research Articles
Nanoleakage of apical sealing using a calcium silicate-based sealer according to canal drying methods
Yoon-Joo Lee, Kyung-Mo Cho, Se-Hee Park, Yoon Lee, Jin-Woo Kim
Restor Dent Endod 2024;49(2):e20.   Published online April 19, 2024
DOI: https://doi.org/10.5395/rde.2024.49.e20
AbstractAbstract PDFPubReaderePub
Objectives

This study investigated the nanoleakage of root canal obturations using calcium silicate-based sealer according to different drying methods.

Materials and Methods

Fifty-two extracted mandibular premolars with a single root canal and straight root were selected for this study. After canal preparation with a nickel-titanium rotary file system, the specimens were randomly divided into 4 groups according to canal drying methods (1: complete drying, 2: blot drying/distilled water, 3: blot drying/NaOCl, 4: aspiration only). The root canals were obturated using a single-cone filling technique with a calcium silicate–based sealer. Nanoleakage was evaluated using a nanoflow device after 24 hours, 1 week, and 1 month. Data were collected twice per second at the nanoscale and measured in nanoliters per second. Data were statistically analyzed using the Kruskal-Wallis and Mann–Whitney U-tests (p < 0.05).

Results

The mean flow rate measured after 24 hours showed the highest value among the time periods in all groups. However, the difference in the flow rate between 1 week and 1 month was not significant. The mean flow rate of the complete drying group was the highest at all time points. After 1 month, the mean flow rate in the blot drying group and the aspiration group was not significantly different.

Conclusions

Within the limitations of this study, the canal drying method had a significant effect on leakage and sealing ability in root canal obturations using a calcium silicate-based sealer. Thus, a proper drying procedure is critical in endodontic treatment.

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The status of clinical trials regarding root canal sealers
Ahmad AL Malak, Yasmina EL Masri, Mira Al Ziab, Nancy Zrara, Tarek Baroud, Pascale Salameh
Restor Dent Endod 2024;49(1):e5.   Published online January 15, 2024
DOI: https://doi.org/10.5395/rde.2024.49.e5
AbstractAbstract PDFPubReaderePub
Objectives

This study aimed to present the results and analyses of clinical trials, including updates on the different functions of root canal sealers.

Materials and Methods

In June 2023, we performed a comprehensive search of ClinicalTrials.gov to identify interventional clinical trials pertaining to root canal sealers. In total, 23 clinical trials conducted up to June 2023 were included in this study.

Results

Approximately half of the trials (11 out of 23) were completed, while none were terminated or withdrawn. Each included trial had a minimum of 10 participants, with 11 trials having more than 100 participants. None of the assessed trials provided outcomes, and the majority (17 out of 23) lacked associated publications. In terms of geographic distribution, the USA and Canada did not contribute to any root canal sealer trials.

Conclusions

This study highlights the lack of diversity in trial locations, the absence of reported results, and a scarcity of clinical trials examining the physicochemical properties of different sealers. Most published trials primarily focused on assessing the post-operative pain effect of these sealers, but no significant difference was found regarding post-operative pain control.

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Push-out bond strength and intratubular biomineralization of a hydraulic root-end filling material premixed with dimethyl sulfoxide as a vehicle
Ju-Ha Park, Hee-Jin Kim, Kwang-Won Lee, Mi-Kyung Yu, Kyung-San Min
Restor Dent Endod 2023;48(1):e8.   Published online January 20, 2023
DOI: https://doi.org/10.5395/rde.2023.48.e8
AbstractAbstract PDFPubReaderePub
Objectives

This study was designed to evaluate the parameters of bonding performance to root dentin, including push-out bond strength and dentinal tubular biomineralization, of a hydraulic bioceramic root-end filling material premixed with dimethyl sulfoxide (Endocem MTA Premixed) in comparison to a conventional powder-liquid–type cement (ProRoot MTA).

Materials and Methods

The root canal of a single-rooted premolar was filled with either ProRoot MTA or Endocem MTA Premixed (n = 15). A slice of dentin was obtained from each root. Using the sliced specimen, the push-out bond strength was measured, and the failure pattern was observed under a stereomicroscope. The apical segment was divided into halves; the split surface was observed under a scanning electron microscope, and intratubular biomineralization was examined by observing the precipitates formed in the dentinal tubule. Then, the chemical characteristics of the precipitates were evaluated with energy-dispersive X-ray spectroscopic (EDS) analysis. The data were analyzed using the Student’s t-test followed by the Mann-Whitney U test (p < 0.05).

Results

No significant difference was found between the 2 tested groups in push-out bond strength, and cohesive failure was the predominant failure type. In both groups, flake-shaped precipitates were observed along dentinal tubules. The EDS analysis indicated that the mass percentage of calcium and phosphorus in the precipitate was similar to that found in hydroxyapatite.

Conclusions

Regarding bonding to root dentin, Endocem MTA Premixed may have potential for use as an acceptable root-end filling material.

Citations

Citations to this article as recorded by  
  • Effectiveness of Sectioning Method and Filling Materials on Roughness and Cell Attachments in Root Resection Procedure
    Tarek Ashi, Naji Kharouf, Olivier Etienne, Bérangère Cournault, Pierre Klienkoff, Varvara Gribova, Youssef Haikel
    European Journal of Dentistry.2025; 19(01): 240.     CrossRef
  • Bond Strength and Adhesive Interface Quality of New Pre‐Mixed Bioceramic Root Canal Sealer
    Gustavo Creazzo, Bruna Monteiro de Barros Ciribelli Alves, Helena Cristina de Assis, Karen Gisselle Garay Villamayor, Manoel Damião de Sousa‐Neto, Jardel Francisco Mazzi‐Chaves, Fabiane Carneiro Lopes‐Olhê
    Microscopy Research and Technique.2025;[Epub]     CrossRef
  • Evaluation of the root dentin bond strength and intratubular biomineralization of a premixed calcium aluminate-based hydraulic bioceramic endodontic sealer
    Yu-Na Lee, Min-Kyeong Kim, Hee-Jin Kim, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
    Journal of Oral Science.2024; 66(2): 96.     CrossRef
  • Removal efficiency of a fast setting pozzalan-based bioactive cement: a micro CT study
    Feyza Çetinkaya, Ahter Şanal Çıkman, Ali Keleş, Banu Arıcıoğlu
    BMC Oral Health.2024;[Epub]     CrossRef
  • Antibacterial Activity and Sustained Effectiveness of Calcium Silicate-Based Cement as a Root-End Filling Material against Enterococcus faecalis
    Seong-Hee Moon, Seong-Jin Shin, Seunghan Oh, Ji-Myung Bae
    Materials.2023; 16(18): 6124.     CrossRef
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  • 5 Crossref
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Effects of calcium silicate cements on neuronal conductivity
Derya Deniz-Sungur, Mehmet Ali Onur, Esin Akbay, Gamze Tan, Fügen Daglı-Comert, Taner Cem Sayın
Restor Dent Endod 2022;47(2):e18.   Published online March 7, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e18
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated alterations in neuronal conductivity related to calcium silicate cements (CSCs) by investigating compound action potentials (cAPs) in rat sciatic nerves.

Materials and Methods

Sciatic nerves were placed in a Tyrode bath and cAPs were recorded before, during, and after the application of test materials for 60-minute control, application, and recovery measurements, respectively. Freshly prepared ProRoot MTA, MTA Angelus, Biodentine, Endosequence RRM-Putty, BioAggregate, and RetroMTA were directly applied onto the nerves. Biopac LabPro version 3.7 was used to record and analyze cAPs. The data were statistically analyzed.

Results

None of the CSCs totally blocked cAPs. RetroMTA, Biodentine, and MTA Angelus caused no significant alteration in cAPs (p > 0.05). Significantly lower cAPs were observed in recovery measurements for BioAggregate than in the control condition (p < 0.05). ProRoot MTA significantly but transiently reduced cAPs in the application period compared to the control period (p < 0.05). Endosequence RRM-Putty significantly reduced cAPs.

Conclusions

Various CSCs may alter cAPs to some extent, but none of the CSCs irreversibly blocked them. The usage of fast-setting CSCs during apexification or regeneration of immature teeth seems safer than slow-setting CSCs due to their more favorable neuronal effects.

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Effect of irrigants on the color stability, solubility, and surface characteristics of calcium-silicate based cements
Selen Küçükkaya Eren, Sevinc Askerbeyli Örs, Hacer Aksel, Şenay Canay, Duygu Karasan
Restor Dent Endod 2022;47(1):e10.   Published online February 10, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e10
AbstractAbstract PDFPubReaderePub
Objectives

This study aimed to investigate the color stability, solubility, and surface characteristics of 3 calcium silicate-based cements (CSCs) after immersion in different solutions.

Materials and Methods

ProRoot white mineral trioxide aggregate (MTA), Biodentine, and Endosequence Root Repair Material (ERRM) were placed in cylindrical molds and stored at 37°C for 24 hours. Each specimen was immersed in distilled water, 5% sodium hypochlorite (NaOCl), 2% chlorhexidine, or 0.1% octenidine hydrochloride (OCT) for 24 hours. Color changes were measured with a spectrophotometer. Solubility was determined using an analytical balance with 10−5 g accuracy. The surface characteristics were analyzed using scanning electron microscopy and energy-dispersive spectroscopy. Data were analyzed using 2-way analysis of variance, the Tukey test, and the paired t-test.

Results

MTA exhibited significant discoloration in contact with NaOCl (p < 0.05). White precipitation occurred on the surfaces of Biodentine and ERRM after contact with the solutions, and none of the materials presented dark brown discoloration. All materials showed significant solubility after immersion in the solutions (p < 0.05), irrespective of the solution type (p > 0.05). The surface topography and elemental composition of the samples showed different patterns of crystal formation and precipitation depending on the solution type.

Conclusions

All materials presented some amount of solubility and showed crystal precipitation after contact with the solutions. Biodentine and ERRM are suitable alternatives to ProRoot MTA as they do not exhibit discoloration. The use of OCT can be considered safe for CSCs.

Citations

Citations to this article as recorded by  
  • Chemical and in vivo analyses of calcium silicate‐based materials in bone and connective tissues
    Ana Cristina Padilha Janini, Lauter Eston Pelepenko, Brenda Fornazaro Moraes, Victor Augusto Benedicto dos Santos, Matheus Barros‐Costa, Isabela Alvarenga Maciel dos Santos, Fábio Roberto de Souza Batista, Juliana de Aguiar Silveira Meira, Mariza Akemi Ma
    International Endodontic Journal.2025; 58(3): 484.     CrossRef
  • Topic: Perspectives on Success and Failure of Endodontic Treatments
    Ilma Robo, Manola Kelmendi, Eva Habazaj, Kleves Elezi, Rialda Xhizdari, Nevila Alliu
    SN Comprehensive Clinical Medicine.2025;[Epub]     CrossRef
  • The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery: a randomized controlled trial
    Xu Dong, Qin Su, Wen Li, Jinbo Yang, Dongzhe Song, Jing Yang, Xin Xu
    Clinical Oral Investigations.2024;[Epub]     CrossRef
  • How Does Ethylenediaminetetraacetic Acid Irrigation Affect Biodentine? A Multimethod Ex Vivo Study
    Katarzyna Dąbrowska, Aleksandra Palatyńska-Ulatowska, Leszek Klimek
    Materials.2024; 17(6): 1230.     CrossRef
  • Color stability and solubility of Biodentine and NeoPutty in contact with different irrigation solutions
    Sıla Nur Usta, Cangül Keskin
    Restorative Dentistry & Endodontics.2024;[Epub]     CrossRef
  • The impact of various irrigation solutions on the color stabilities of five calcium silicate cement: an in-vitro study
    Aslı Soğukpınar Onsuren, Onur Kesici, Elif Uğurbekler Hündü
    Selcuk Dental Journal.2024; 11(3): 313.     CrossRef
  • Bioceramics in Endodontics: Updates and Future Perspectives
    Xu Dong, Xin Xu
    Bioengineering.2023; 10(3): 354.     CrossRef
  • Effect of calcium silicate-based endodontic sealers on tooth color: A 3-year in vitro experimental study
    Carmen Llena, Ana Herrero, Sandra Lloret, Martha Barraza, Jose Luis Sanz
    Heliyon.2023; 9(2): e13237.     CrossRef
  • Evaluation of the Shear Bond Strength of Four Bioceramic Materials with Different Restorative Materials and Timings
    Abeer S. Alqahtani, Ayman M. Sulimany, Abdullah S. Alayad, Abdulaziz S. Alqahtani, Omar A. Bawazir
    Materials.2022; 15(13): 4668.     CrossRef
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Comparison of the sealing ability of various bioceramic materials for endodontic surgery
Benjamin Rencher, Ana M. Chang, Hanson Fong, James D. Johnson, Avina Paranjpe
Restor Dent Endod 2021;46(3):e35.   Published online June 8, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e35
AbstractAbstract PDFPubReaderePub
Objectives

Endosequence Bioceramic Root Repair Material (BC-RRM) is used in endodontic microsurgery. It is available as a paste and a putty. However, no studies to date have examined the sealing ability of these forms alone or in combination as root-end filling materials. Hence, this study aimed to compare the sealing properties of these 2 forms of BC-RRM.

Materials and Methods

Forty-two extracted upper anterior teeth were divided into 3 experimental groups, a positive and negative control. After the root canal treatment, the root ends were resected, retroprepared and retrofilled with either putty, paste + putty or mineral trioxide aggregate (MTA). The teeth were mounted in tubes so the apical 3 mm was submerged in Brain Heart Infusion (BHI) broth. The coronal portions of the canals were inoculated with Enterococcus faecalis and BHI broth and incubated for 30 days. The broth in the tubes was analyzed for colony forming units to check for leakage of bacteria from the canal. The teeth from the groups were sectioned and analyzed using scanning electron microscopy (SEM). The Kruskal-Wallis test and analysis of variance were used to analyze the data with a significance level p < 0.05.

Results

The BC-RRM and MTA groups showed similar sealing ability. The positive control showed leakage in all samples. The SEM imaging showed the presence of bacteria in all experimental groups at the material-tooth interface.

Conclusions

No significant differences were noted in the experimental groups, providing sufficient evidence that any combination could be effectively used during endodontic microsurgery.

Citations

Citations to this article as recorded by  
  • An Ex-vivo Evaluation of Sealability of Three Bioceramic Physical Variants in Coronal and Apical Thirds of Root Canals
    Murali H Rao, Rajkumar Krishnan, Pavithra Gopal, Elizabeth Thomas
    The Journal of Contemporary Dental Practice.2025; 25(11): 1022.     CrossRef
  • Clinical applications and classification of calcium silicate-based cements based on their history and evolution: a narrative review
    Kenta Tsuchiya, Salvatore Sauro, Hidehiko Sano, Jukka P. Matinlinna, Monica Yamauti, Shuhei Hoshika, Yu Toida, Rafiqul Islam, Atsushi Tomokiyo
    Clinical Oral Investigations.2025;[Epub]     CrossRef
  • Evaluation of the Marginal Adaptation of Two Hydraulic Calcium Silicate Cements Used in Apical Plugs: An In Vitro Study
    Sara Filipe, José Pedro Martinho, Siri Paulo, Catarina Carvalho, Ana Coelho, Inês Amaro, Eunice Carrilho, Anabela Paula, Carlos Miguel Marto, Henrique Girão, Mónica Zuzarte, Ana S. Pires, Manuel Marques Ferreira
    Applied Sciences.2024; 14(2): 480.     CrossRef
  • A Study on Nanoleakage of Apical Retrograde Filling of Premixed Calcium Silicate-Based Cement Using a Lid Technique
    Nyamsuren Enkhbileg, Jin Woo Kim, Seok Woo Chang, Se-Hee Park, Kyung Mo Cho, Yoon Lee
    Materials.2024; 17(10): 2366.     CrossRef
  • The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery: a randomized controlled trial
    Xu Dong, Qin Su, Wen Li, Jinbo Yang, Dongzhe Song, Jing Yang, Xin Xu
    Clinical Oral Investigations.2024;[Epub]     CrossRef
  • Bacterial sealing ability of calcium silicate-based sealer for endodontic surgery: an in-vitro study
    Mai M. Mansour, Sybel M. Moussa, Marwa A. Meheissen, Mahmoud R. Aboelseoud
    BMC Oral Health.2024;[Epub]     CrossRef
  • Evaluation of Marginal Adaptation of Three Biomaterials as Apical Barrier in Experimental Apexification Model
    Nagehan Aktaş, Didem Sakaryalı Uyar, Didem Atabek
    ADO Klinik Bilimler Dergisi.2024; 13(3): 409.     CrossRef
  • In vitro evaluation of the sealing ability of combined use of iRoot BP Plus and iRoot SP for root-end filling
    Xu Dong, Qian Xie, Xin Xu
    Clinical Oral Investigations.2023; 27(6): 2969.     CrossRef
  • Outcomes of endodontic microsurgery using different calcium silicate–based retrograde filling materials: a cohort retrospective cone-beam computed tomographic analysis
    Rawan F. Eskandar, Mey A. Al-Habib, Mohammed A. Barayan, Hadeel Y. Edrees
    BMC Oral Health.2023;[Epub]     CrossRef
  • Bioceramics in Endodontics: Updates and Future Perspectives
    Xu Dong, Xin Xu
    Bioengineering.2023; 10(3): 354.     CrossRef
  • Biological properties of Ceraputty as a retrograde filling material: an in vitro study on hPDLSCs
    Sergio López-García, Francisco J. Rodríguez-Lozano, José Luis Sanz, Leopoldo Forner, María Pilar Pecci-Lloret, Adrián Lozano, Laura Murcia, Sonia Sánchez-Bautista, Ricardo E. Oñate-Sánchez
    Clinical Oral Investigations.2023; 27(8): 4233.     CrossRef
  • Bone Window Technique in Endodontic Microsurgery – Report of Two Cases
    Spyros Floratos, Vasileios Molonis, Apostolos Tsolakis, Stylianos Kykalos, Konstantinos Kontzoglou
    Journal of Endodontic Microsurgery.2022; 2: 24.     CrossRef
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  • 10 Web of Science
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Flow characteristics and alkalinity of novel bioceramic root canal sealers
Anastasios Katakidis, Konstantinos Sidiropoulos, Elisabeth Koulaouzidou, Christos Gogos, Nikolaos Economides
Restor Dent Endod 2020;45(4):e42.   Published online August 18, 2020
DOI: https://doi.org/10.5395/rde.2020.45.e42
AbstractAbstract PDFPubReaderePub
Objective

This study aimed to examine the physical properties (pH and flow) of 2 novel bioceramic sealers.

Materials and Methods

The tested sealers were a calcium hydroxide sealer (Sealapex) and 2 bioceramic sealers (BioRoot RCS and TotalFill BC Sealer). Flow measurements were conducted according to ISO 6876/2012, with a press method of 0.05 mL of sealer. The pH of fresh samples was tested immediately after manipulation, while set samples were stored for 3 times the recommended setting time. The predetermined time intervals ranged from 3 minutes to 24 hours for fresh samples and from 10 minutes to 7 days and 4 weeks for the set samples. Analysis of variance was performed, with p = 0.05 considered indicating significance.

Results

The mean flow values were 26.99 mm for BioRoot, 28.19 for Sealapex, and 30.8 mm for TotalFill BC Sealer, satisfying the ISO standard. In the set samples, BioRoot RCS had higher pH values at 24 hours to 1 week after immersion in distilled water. At 2 weeks, both bioceramic sealers had similar pH values, greater than that of Sealapex. In the fresh samples, the bioceramic sealers had significantly higher initial pH values than Sealapex (p < 0.05). At 24 hours post-immersion, all sealers showed an alkaline pH, with the highest pH observed for TotalFill.

Conclusions

The TotalFill BC Sealer demonstrated the highest flow. The bioceramic sealers initially presented higher alkaline activity than the polymeric calcium hydroxide sealer. However, at 3 and 4 weeks post-immersion, all sealers had similar pH values.

Citations

Citations to this article as recorded by  
  • Physicochemical properties of AH plus bioceramic sealer, Bio-C Sealer, and ADseal root canal sealer
    Tamer M. Hamdy, Manar M. Galal, Amira Galal Ismail, Shehabeldin Saber
    Head & Face Medicine.2024;[Epub]     CrossRef
  • Characterization and Assessment of Physical Properties of 3 Single Syringe Hydraulic Cement–based Sealers
    Veksina Raman, Josette Camilleri
    Journal of Endodontics.2024; 50(3): 381.     CrossRef
  • The Impact of Silver Nanoparticles on Dentinal Tubule Penetration of Endodontic Bioceramic Sealer
    Sundus Bukhary, Sarah Alkahtany, Amal Almohaimede, Nourah Alkhayatt, Shahad Alsulaiman, Salma Alohali
    Applied Sciences.2024; 14(24): 11639.     CrossRef
  • Influence of root canal moisture on the penetration of TotalFill bioceramic sealer into the dentinal tubules: A confocal laser scanning microscopy study
    Archika M Singh, Tarek M Elsewify, Walid S El-Sayed, Husam H Nuawafleh, Ranya F Elemam, Bassem M Eid
    Saudi Endodontic Journal.2024; 14(2): 187.     CrossRef
  • Unusual Canal Morphology in Mandibular Premolars With Two Distal and One Mesial Canal: A Case Series
    Jinesh A, Sanjana Jayakumar Nair, Saurabh Gupta, Harsh Chansoria, Gaurav Rawat
    Cureus.2024;[Epub]     CrossRef
  • A scientometric, bibliometric, and thematic map analysis of hydraulic calcium silicate root canal sealers
    Anastasios Katakidis, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos
    Restorative Dentistry & Endodontics.2023;[Epub]     CrossRef
  • Thermal, chemical and physical analysis of VDW.1Seal, Fill Root ST, and ADseal root canal sealers
    Shehabeldin Saber, Manar M. Galal, Amira Galal Ismail, Tamer M. Hamdy
    Scientific Reports.2023;[Epub]     CrossRef
  • α-tricalcium phosphate/fluorapatite-based cement - promising dental root canal filling material
    Abdul Kazuz, Zeljko Radovanovic, Djordje Veljovic, Vesna Kojic, Dimitar Jakimov, Tamara Vlajic-Tovilovic, Vesna Miletic, Rada Petrovic, Djordje Janackovic
    Processing and Application of Ceramics.2022; 16(1): 22.     CrossRef
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A micro-computed tomographic study of remaining filling materials of two bioceramic sealers and epoxy resin sealer after retreatment
KyungJae Kim, Da Vin Kim, Sin-Young Kim, SungEun Yang
Restor Dent Endod 2019;44(2):e18.   Published online April 26, 2019
DOI: https://doi.org/10.5395/rde.2019.44.e18
AbstractAbstract PDFPubReaderePub
Objective

This study evaluated the presence of residual root canal filling material after retreatment using micro-computed tomography (micro-CT).

Materials and Methods

Extracted human teeth (single- and double-rooted, n = 21/each; C-shaped, n = 15) were prepared with ProFile and randomly assigned to three subgroups for obturation with gutta-percha and three different sealers (EndoSeal MTA, EndoSequence BC sealer, and AH Plus). After 10 days, the filling material was removed and the root canals were instrumented one size up from the previous master apical file size. The teeth were scanned using micro-CT before and after retreatment. The percentage of remaining filling material after retreatment was calculated at the coronal, middle, and apical thirds. Data were analyzed using the Kruskal-Wallis test and Mann-Whitney U test with Bonferroni post hoc correction.

Results

The tested sealers showed no significant differences in the percentage of remaining filling material in single- and double-rooted teeth, although EndoSeal MTA showed the highest value in C-shaped roots (p < 0.05). The percentage of remaining filling material of AH Plus and EndoSeal MTA was significantly higher in C-shaped roots than in single- or double-roots (p < 0.05), while that of BC sealer was similar across all root types. EndoSeal MTA showed the highest values at the apical thirds of single- and double-roots (p < 0.05); otherwise, no significant differences were observed among the coronal, middle, and apical thirds.

Conclusions

Within the limitations of this study, a large amount of EndoSeal MTA remained after retreatment, especially in C-shaped root canals.

Citations

Citations to this article as recorded by  
  • Root canal cleanliness and debris extrusion following retreatment of thermoplastic injection technique and bioceramic-based root canal sealer
    Deniz Bender, Mert Ocak, Emel Uzunoğlu Özyürek
    Clinical Oral Investigations.2024;[Epub]     CrossRef
  • The Effect of Different Obturation Techniques Using Different Root Canal Sealers on the Residual Filling Material After Retreatment Procedures
    M Sarı, K Yılmaz
    Nigerian Journal of Clinical Practice.2024; 27(2): 174.     CrossRef
  • Effect of Different Obturation Techniques on the Amount of Debris Extrusion During Endodontic Retreatment Using XP Endo Retreatment Set Files (In vitro Study)
    Pawan Amin, Hawzhen Saeed
    Sulaimani Dental Journal.2023; 10(3): 9.     CrossRef
  • The efficiency of different irrigation activation techniques in the removal of calcium silicate‐based endodontic sealer from artificially created groove
    Meltem Sümbüllü, Afzal Ali, Mine Büker, Hakan Arslan
    Australian Endodontic Journal.2023; 49(S1): 238.     CrossRef
  • Efficiency of diode laser and ultrasonic‐activated irrigation in retreatment of gutta percha and bioceramic sealer: An in vitro study
    Rahaf A. Almohareb, Reem M. Barakat, Noor Aljarallah, Halah Mudhish, Amjaad Almutairi, Fahda N. Algahtani
    Australian Endodontic Journal.2023; 49(2): 318.     CrossRef
  • Efficiency of the new reciprocating and rotary systems with or without ultrasonics in removing root-canals filling with calcium silicate-based sealer (MTA)
    Ahmad A. Madarati, Aya M. N. Sammani, Ahmad A. Alnazzawi, Ali Alrahlah
    BMC Oral Health.2023;[Epub]     CrossRef
  • Retreatability of calcium silicate‐based root canal sealer using reciprocating instrumentation with different irrigation activation techniques in single‐rooted canals
    Daniele Angerame, Matteo De Biasi, Davide Porrelli, Lorenzo Bevilacqua, Riccardo Zanin, Matteo Olivi, Vassilios Kaitsas, Giovanni Olivi
    Australian Endodontic Journal.2022; 48(3): 415.     CrossRef
  • Critical analysis of research methods and experimental models to study removal of root filling materials
    Mahdi A. Ajina, Pratik K. Shah, Bun San Chong
    International Endodontic Journal.2022; 55(S1): 119.     CrossRef
  • An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy
    Fateme Eskandari, Alireza Razavian, Rozhina Hamidi, Khadije Yousefi, Susan Borzou, Zohaib Khurshid
    International Journal of Dentistry.2022; 2022: 1.     CrossRef
  • How do imaging protocols affect the assessment of root-end fillings?
    Fernanda Ferrari Esteves Torres, Reinhilde Jacobs, Mostafa EzEldeen, Karla de Faria-Vasconcelos, Juliane Maria Guerreiro-Tanomaru, Bernardo Camargo dos Santos, Mário Tanomaru-Filho
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Bacterial leakage and micro-computed tomography evaluation in round-shaped canals obturated with bioceramic cone and sealer using matched single cone technique
Kallaya Yanpiset, Danuchit Banomyong, Kanet Chotvorrarak, Ratchapin Laovanitch Srisatjaluk
Restor Dent Endod 2018;43(3):e30.   Published online July 5, 2018
DOI: https://doi.org/10.5395/rde.2018.43.e30
AbstractAbstract PDFPubReaderePub
Objectives

To evaluate sealing ability of root canals obturated with bioceramic-impregnated gutta percha cone (BCC) or gutta percha (GP), with bioceramic sealer (BCS) or AH Plus (AH; Dentsply-Maillefer), in roundly-prepared canals using matched single-cone technique, based on bacterial leakage test, and to analyze obturation quality using micro-computed tomography (CT) analysis.

Materials and Methods

Ninety-two distobuccal roots of maxillary molars were prepared using nickel-titanium files to apical size 40/0.06. The roots were divided into 4 groups (n = 20) that were obturated with a master cone and sealer: GP/AH, BCC/AH, GP/BCS, and BCC/BCS. Bacterial leakage model using Enterococcus faecalis was used to evaluate sealing ability for 60-day period. Obturated samples from each group (n = 4) were analyzed using micro-CT.

Results

All groups showed bacterial leakage at 20%–45% of samples with mean leakage times of 42–52 days. There were no significant differences in bacterial leakage among the groups. Micro-CT showed minimal gaps and voids in all groups at less than 1%.

Conclusions

In roundly-prepared canals, the single cone obturation with BCC/BCS was comparable to GP/AH for bacterial leakage at 60 days.

Citations

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