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Volume 38 (4); November 2013
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Review Article
Cardiovascular effect of epinephrine in endodontic microsurgery: a review
Youngjune Jang, Euiseong Kim
Restor Dent Endod 2013;38(4):187-193.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.187
AbstractAbstract PDFPubReaderePub

Epinephrine is one of the most widely-used vasoconstrictors in dental treatment including endodontic microsurgery. However, the systemic safety of epinephrine has been in debate for many years because of its potential risk to cause cardiovascular complications. The purpose of this review was to assess the cardiovascular effect of epinephrine use in endodontic microsurgery. Endodontic microsurgery directly applies epinephrine into the bone cavity, and the amount is reported to be much larger than other dental surgeries. Moreover, when considering that systemic potency of intraosseous application is reported to be comparable to intravenous application, the systemic influence of epinephrine could be increased in endodontic microsurgery. Besides, pre-existing cardiovascular complications or drug interactions can enhance its systemic influence, resulting in increased susceptibility to cardiovascular complications. Although clinical studies have not reported significant complications for patients without severe systemic complications, many epinephrine-induced emergency cases are warning the cardiovascular risk related with pre-existing systemic disease or drug interactions. Epinephrine is a dose-sensitive drug, and its hypersensitivity reaction can be fatal to patients when it is related to cardiovascular complications. Therefore, clinicians should recognize the risk, and the usage of pre-operative patient evaluation, dose control and patient monitoring are required to ensure patient's safety during endodontic microsurgery.

Citations

Citations to this article as recorded by  
  • Expert consensus on apical microsurgery
    Hanguo Wang, Xin Xu, Zhuan Bian, Jingping Liang, Zhi Chen, Benxiang Hou, Lihong Qiu, Wenxia Chen, Xi Wei, Kaijin Hu, Qintao Wang, Zuhua Wang, Jiyao Li, Dingming Huang, Xiaoyan Wang, Zhengwei Huang, Liuyan Meng, Chen Zhang, Fangfang Xie, Di Yang, Jinhua Yu
    International Journal of Oral Science.2025;[Epub]     CrossRef
  • Effects of nasal desmopressin spray versus topical epinephrine on surgical field clarity and hemodynamics in endonasal dacryocystorhinostomy: a randomized clinical study
    Mohamed G.M. El Sayed, Marwa M. Medhat, Dina A.E. Salem, Marwa A.M. Khedr, Alshaimaa A.F. Kamel
    Research and Opinion in Anesthesia & Intensive Care.2024; 11(1): 1.     CrossRef
  • Is 1:1000 adrenaline as a topical haemostat an effective alternative to control bleeding in dentistry and oral surgery?
    Raj D. Aslam, Jonathan Liew, Eleni Besi
    British Dental Journal.2023; 235(1): 29.     CrossRef
  • Effect of Flumazenil on Emergence Agitation after Orthognathic Surgery: A Randomized Controlled Trial
    Young Hyun Koo, Geun Joo Choi, Hyun Kang, Yong Hun Jung, Young Cheol Woo, Young-Jun Choi, Chong Wha Baek
    Journal of Personalized Medicine.2022; 12(3): 416.     CrossRef
  • Hemostatic agents in periapical surgery: The systematic review
    Z. S. Khabadze, D. A. Nazarova, E. S. Shilyaeva, A. P. Kotelnikova, Yu. A. Bakayev, S. M. Abdulkerimova, Kh. O. Omarova
    Endodontics Today.2021; 19(3): 184.     CrossRef
  • THE EFFECT OF ADRENALINE ON DYNAMICS OF CARBOHYDRATE METABOLISM INDICES IN RATS
    S. Shkurashivska, H. Ersteniuk
    Visnyk of Lviv University. Biological series.2017; (75): 151.     CrossRef
  • The Correlation between the Blood Sugar and Allergy of the Trauma Patient
    Jeong Soo Lee, Sung Hee Hyun, Ji-Sook Lee, In Sik Kim
    Korean Journal of Clinical Laboratory Science.2014; 46(1): 22.     CrossRef
  • Biologic response of local hemostatic agents used in endodontic microsurgery
    Youngjune Jang, Hyeon Kim, Byoung-Duck Roh, Euiseong Kim
    Restorative Dentistry & Endodontics.2014; 39(2): 79.     CrossRef
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Research Articles
Enamel matrix derivative for replanted teeth in animal models: a systematic review and meta-analysis
Sahng G. Kim, Steven I. Ryu
Restor Dent Endod 2013;38(4):194-203.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.194
AbstractAbstract PDFPubReaderePub
Objectives

To investigate the effect of enamel matrix derivative (EMD) on periodontal healing of replanted teeth in animal models.

Materials and Methods

The authors searched MEDLINE, PubMed, EMBASE, Cochrane Library, Web of Knowledge and Scopus for articles published up to Oct 2012. Animal studies in which EMD was applied in transplanted or replanted teeth with adequate controls and histological data were considered. Normal periodontal healing or root resorption determined by histology after EMD was applied in replanted teeth with adequate controls was used as outcome measures. The following search strategy was used: ('Emdogain' OR 'enamel matrix proteins' OR 'enamel matrix derivative') AND ('avulsion' OR 'transplantion' OR 'autotransplantation' OR 'replantation').

Results

Six animal studies were included in the final review. There was great heterogeneity in study design among included studies. Two studies with similar study designs were identified and analyzed by a meta-analysis. The pooled estimates showed a significantly higher normal healing and surface resorption and significantly less inflammatory and replacement resorption in EMD-treated groups compared with non-EMD-treated groups.

Conclusions

With the limitations of this systematic review, the use of EMD led to greater normal periodontal healing and surface root resorption and less inflammatory and replacement root resorption in the presence of periodontal ligaments. However, no definite conclusion could be drawn with regard to the effect of EMD on periodontal healing and root resorption when no periodontal ligaments exist.

Citations

Citations to this article as recorded by  
  • Intentional Replantation of Failed Root Canal Treated Tooth
    Pritesh Kisanlal Agrawal, Narayan G. Jibhkate, Saurabh A. Redij
    Journal of Interdisciplinary Dentistry.2024; 14(2): 128.     CrossRef
  • Enamel matrix derivative in the treatment of tooth replantation: from a biological basis to clinical application
    Yao Lin, Liangping Chen, Yuling Xu, Mingwei Xu, Qinghua Liu, Junbing He
    Annals of Medicine.2024;[Epub]     CrossRef
  • Fibrillin protein, a candidate for creating a suitable scaffold in PDL regeneration while avoiding ankylosis
    Kyoko Oka
    genesis.2022;[Epub]     CrossRef
  • Can delayed grafting of frozen teeth achieve periodontal ligament healing?
    Yue Chen, Liang Chen, Min Zhou, Shouyin Yi, Juan Ran, Yuansi Long, Jing Luo, Kun Tian
    Medical Hypotheses.2022; 167: 110945.     CrossRef
  • Permanent tooth avulsion in children and adults: Therapeutic options for longer survival
    Simona Stojanović, Miloš Tijanić, Kristina Burić, Nina Burić, Milan Spasić, Kosta Todorović, Branislava Stojković, Marija Jovanović, Milica Petrović, Dušan Mitić
    Acta stomatologica Naissi.2021; 37(83): 2213.     CrossRef
  • Evidence mapping and quality assessment of systematic reviews in dental traumatology
    Nitesh Tewari, Vijay Prakash Mathur, Amandeep Kaur, Divesh Sardana, Morankar Rahul, Rigzen Tamchos, Priyanshi Ritwik, Shubhi Goel, Julie Schiavo
    Dental Traumatology.2021; 37(1): 17.     CrossRef
  • Application of Enamel Matrix Derivative (Emdogain) in Endodontic Therapy: A Comprehensive Literature Review
    Howard H. Wang, Nima D. Sarmast, Elham Shadmehr, Nikola Angelov, Shahrokh Shabahang, Mahmoud Torabinejad
    Journal of Endodontics.2018; 44(7): 1066.     CrossRef
  • Periodontal wound healing following reciprocal autologous root transplantation in class III furcation defects
    Naoshi Takeuchi, Yoshinori Shirakata, Yukiya Shinohara, Kotaro Sena, Kazuyuki Noguchi
    Journal of Periodontal & Implant Science.2017; 47(6): 352.     CrossRef
  • Effects of Fibrillin Application on Periodontal Ligament Regeneration in Mouse Model of Tooth Replantation
    Shougo Tamura, Kyoko Oka, Satoshi Itaya, Michiko Kira-Tatsuoka, Masako Toda, Arisa Higa, Masao Ozaki
    Journal of Hard Tissue Biology.2016; 25(3): 295.     CrossRef
  • Autotransplantation: a viable treatment option for adolescent patients with significantly compromised teeth
    D Ong, Y Itskovich, G Dance
    Australian Dental Journal.2016; 61(4): 396.     CrossRef
  • Influence of enamel matrix derivative on healing of root surfaces after bonding treatment and intentional replantation of vertically fractured roots
    Tsutomu Sugaya, Mahito Tomita, Youji Motoki, Hirofumi Miyaji, Masamitsu Kawamami
    Dental Traumatology.2016; 32(5): 397.     CrossRef
  • The effect of cathepsin K inhibitor on osteoclastic activity compared to alendronate and enamel matrix protein
    Wonkyung Yang, Hyunjung Ko, Heesun Kim, Miri Kim
    Dental Traumatology.2015; 31(3): 202.     CrossRef
  • The effects of bone morphogenetic protein-2 and enamel matrix derivative on the bioactivity of mineral trioxide aggregate in MC3T3-E1cells
    Youngdan Jeong, Wonkyung Yang, Hyunjung Ko, Miri Kim
    Restorative Dentistry & Endodontics.2014; 39(3): 187.     CrossRef
  • What is the Best Root Surface Treatment for Avulsed Teeth?
    Elif B Tuna , Duygu Yaman , Seiko Yamamato
    The Open Dentistry Journal.2014; 8(1): 175.     CrossRef
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A comparative evaluation of cytotoxicity of root canal sealers: an in vitro study
Gautam Pyarelal Badole, Manjusha Madhukar Warhadpande, Ganesh Kothiramji Meshram, Rakesh Namdeoraoji Bahadure, Shubha Gopal Tawani, Gopal Tawani, Shital Gautam Badole
Restor Dent Endod 2013;38(4):204-209.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.204
AbstractAbstract PDFPubReaderePub
Objectives

The objective of this in vitro study was to evaluate and compare the cytotoxicity of four different root canal sealers i.e. Apexit Plus (Ivoclar Vivadent), Endomethasone N (Septodont), AH-26 (Dentsply) and Pulpdent Root Canal Sealer (Pulpdent), on a mouse fibroblast cell line (L929).

Materials and Methods

Thirty two discs for each sealer (5 mm in diameter and 2 mm in height) were fabricated in Teflon mould. The sealer extraction was made in cell culture medium (Dulbecco's Modified Eagle's Medium, DMEM) using the ratio 1.25 cm2/mL between the surface of the sealer samples and the volume of medium in a shaker incubator. Extraction of each sealer was obtained at 24 hr, 7th day, 14th day, and one month of interval. These extracts were incubated with L929 cell line and 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) assay was done. Two-way ANOVA for interaction effects between sealer and time and Post-hoc multiple comparison using Tukey's test across all the 16 different groups were used for statistical analysis.

Results

Apexit Plus root canal sealer was significantly less toxic than other sealers (p < 0.05) and showed higher cellular growth than control. Endomethasone N showed mild cytotoxicity. AH-26 showed severe toxicity which became mild after one month while Pulpdent Root Canal Sealer showed severe to moderate toxicity.

Conclusions

Apexit Plus was relatively biocompatible sealer as compared to other three sealers which were cytotoxic at their initial stages, however, they became biocompatible with time.

Citations

Citations to this article as recorded by  
  • The Evolution of In Vitro Toxicity Assessment Methods for Oral Cavity Tissues—From 2D Cell Cultures to Organ-on-a-Chip
    Alexandra Jităreanu, Luminița Agoroaei, Ioana-Cezara Caba, Florina-Daniela Cojocaru, Liliana Vereștiuc, Mădălina Vieriu, Ioana Mârțu
    Toxics.2025; 13(3): 195.     CrossRef
  • Comparative analysis of the inflammatory response of human gingival fibroblasts to NeoSEALER Flo and CeraSeal bioceramic sealers: an in vitro study
    Sarah Salah Gaafar, Abdel Rahman O. El Mekkawi, Rehab Ali Farag, Mohamed H. A. Gadelmawla, Ahmad Mostafa Hussein Mohamad Hussein, Mohamed Sayed, Mohammad Rayyan, Doaa Gamal AbdelMouez Basta
    BMC Oral Health.2025;[Epub]     CrossRef
  • Cytotoxicity and Cell Viability of Two Bioactive Root Canal Sealers, Mineral Trioxide Aggregate, and BioRoot Root Canal Sealer: An In Vitro Study
    Emmanuel Samson, Lata B Gangurde, Jaiprakash R Rathod, Pradnya S Jadhav, Sangeeta Ambhore, Pranav S Jadhav
    CODS - Journal of Dentistry.2023; 14(2): 57.     CrossRef
  • Human Gingival Fibroblasts Response to Different Endodontic Sealers: An In Vitro Study
    Rita Noites, Inês Tavares, Miguel Cardoso, Isabel M. Carreira, Maria Bartolomeu, Ana S. Duarte, Ilda P. Ribeiro
    Applied Sciences.2023; 13(19): 10976.     CrossRef
  • Antibacterial and Cytotoxicity of Root Canal Sealer with the Addition of Chitosan Nanoparticle at Various Concentrations
    Diatri Nari Ratih, Ema Mulyawati, Rika Kurnia Santi, Yulita Kristanti
    European Journal of Dentistry.2023; 17(02): 398.     CrossRef
  • Transforaminal and systemic diffusion of an active agent from a zinc oxide eugenol-based endodontic sealer containing hydrocortisone—in an in vivo model
    Davy Aubeux, Anne Valot-Salengro, Gaelle Gautier, Arnaud Malet, Fabienne Pérez
    Clinical Oral Investigations.2020; 24(12): 4395.     CrossRef
  • PEGylated curcumin-loaded nanofibrous mats with controlled burst release through bead knot-on-spring design
    Mahdi Saeed, Hamid Mirzadeh, Mojgan Zandi, Jalal Barzin
    Progress in Biomaterials.2020; 9(4): 175.     CrossRef
  • A New Calcium Silicate-Based Root Canal Dressing: Physical and Chemical Properties, Cytotoxicity and Dentinal Tubule Penetration
    Natália Villa, Vanessa Valgas Dos Santos, Ubirajara Maciel da Costa, Aline Teixeira Mendes, Pedro Henrique Marks Duarte, Ricardo Abreu da Rosa, Jefferson Ricardo Pereira, Marcus Vinícius Reis Só
    Brazilian Dental Journal.2020; 31(6): 598.     CrossRef
  • Evaluation of the Antimicrobial Efficacy of Herbal Extracts Added to Root Canal Sealers of Different Bases: An In Vitro Study
    Abhay M Tripathi, Minarani T Devi, Sonali K Kalra, Ujjala Ghoshal
    International Journal of Clinical Pediatric Dentistry.2019; 12(5): 398.     CrossRef
  • Endodontic-related inferior alveolar nerve injuries: A review and a therapeutic flow chart
    R. Castro, M. Guivarc'h, J.M. Foletti, J.H. Catherine, C. Chossegros, L. Guyot
    Journal of Stomatology, Oral and Maxillofacial Surgery.2018; 119(5): 412.     CrossRef
  • Comparison between direct contact and extract exposure methods for PFO cytotoxicity evaluation
    Girish K. Srivastava, Maria L. Alonso-Alonso, Ivan Fernandez-Bueno, Maria T. Garcia-Gutierrez, Fernando Rull, Jesús Medina, Rosa M. Coco, J. Carlos Pastor
    Scientific Reports.2018;[Epub]     CrossRef
  • Novel endodontic sealers induce cell cytotoxicity and apoptosis in a dose-dependent behavior and favorable response in mice subcutaneous tissue
    L. A. B. Silva, L. U. Azevedo, A. Consolaro, F. Barnett, Y. Xu, R. A. Battaglino, P. S. Cañadas, Katharina Morant Holanda de Oliveira, R. A. B. Silva
    Clinical Oral Investigations.2017; 21(9): 2851.     CrossRef
  • Designing and fabrication of curcumin loaded PCL/PVA multi-layer nanofibrous electrospun structures as active wound dressing
    Seyed Mahdi Saeed, Hamid Mirzadeh, Mojgan Zandi, Jalal Barzin
    Progress in Biomaterials.2017; 6(1-2): 39.     CrossRef
  • 218 View
  • 2 Download
  • 13 Crossref
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Chlorhexidine gel associated with papain in pulp tissue dissolution
Gabriel Couto De Oliveira, Caio Souza Ferraz, Carlos Vieira Andrade Júnior, Matheus Melo Pithon
Restor Dent Endod 2013;38(4):210-214.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.210
AbstractAbstract PDFPubReaderePub
Objectives

This study aimed to evaluate the capacity of 2% chlorhexidine gel associated with 8% papain gel in comparison with 5.25% sodium hypochlorite in bovine pulp tissue dissolution.

Materials and Methods

Ninety bovine pulps of standardized sizes were used and fragmented into 5-mm sizes. The fragments were removed from the root middle third region. They were divided into 6 experimental groups (n = 15), 1) 8% papain; 2) 2% chlorhexidine; 3) 2% chlorhexidine associated with 8% papain; 4) 0.9% saline solution; 5) 2.5% sodium hypochlorite; and 6) 5.25% sodium hypochlorite. The pulp fragments were weighed and put into immobile test tubes for dissolution for time intervals of 30, 60, 90, and 120 min.

Results

The 5.25% sodium hypochlorite had greater dissolution potential than the pure papain, and when associated with chlorhexidine, both promoted greater dissolution than did the saline solution and 2% chlorhexidine groups (p < 0.05). The 2.5% sodium hypochlorite promoted dissolution to a lesser extent than the groups with papain within a period of 30 min (p < 0.05), but, was comparable to the saline solution and chlorhexidine. After 120 min, the 2.5% and 5.25% sodium hypochlorite promoted dissolution of 100% of the pulp fragments, and papain, 61%, while chlorhexidine associated with papain and chlorhexidine alone dissolved only 55% and 3%, respectively.

Conclusions

The 8% papain in gel, both alone and in association with chlorhexidine, was able to dissolve bovine pulp tissue, but to a lesser extent than did 5.25% sodium hypochlorite.

Citations

Citations to this article as recorded by  
  • Effects of traditional and novel proteolytic agents on tissue dissolution and dentine microhardness
    Shwetha Elizabeth Jacob, Niharika Prasad, Sreya Dutta, Vasavi Kumblekar, Srikant Natarajan, Kukkila Jayaprakash, Manuel Sebastian Thomas
    Australian Endodontic Journal.2023; 49(2): 287.     CrossRef
  • A Comparative Evaluation of Pulp Tissue Dissolving Ability of Three Different Pulp Dissolving Agents With 5.25% Sodium Hypochlorite: An In-Vitro Study
    Ganesh Kalandar, Manoj Ramugade, Kishor Sapkale, Abrar Sayed, Sapna Sonkurla
    International Journal of Orofacial Research.2023; 7(2): 42.     CrossRef
  • Effect of bromelain and papain gel on enamel deproteinisation before orthodontic bracket bonding
    Matheus Melo Pithon, Matheus Souza Campos, Raildo da Silva Coqueiro
    Australasian Orthodontic Journal.2016; 32(1): 23.     CrossRef
  • 157 View
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  • 3 Crossref
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Retentive strength of different intracanal posts in restorations of anterior primary teeth: an in vitro study
Mahtab Memarpour, Fereshteh Shafiei, Maryam Abbaszadeh
Restor Dent Endod 2013;38(4):215-221.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.215
AbstractAbstract PDFPubReaderePub
Objectives

To determine the retentive strength and failure mode of undercut composite post, glass fiber post and polyethylene fiber post luted with flowable composite resin and resin-cement.

Materials and Methods

Coronal parts of 120 primary canine teeth were sectioned and specimens were treated endodontically. The teeth were randomly divided into 6 groups (n = 20). Prepared root canals received intracanal retainers with a short composite post, undercut composite post, glass fiber post luted with flowable resin or resin-cement, and polyethylene fiber post luted with flowable resin or resin-cement. After crown reconstruction, samples were tested for retentive strength and failure mode. Statistical analysis was done with one-way ANOVA and Tukey tests (p < 0.05).

Results

There were statistically significant differences between groups (p = 0.001). Mean bond strength in the undercut group was significantly greater than in the short composite post (p = 0.030), and the glass fiber post (p = 0.001) and the polyethylene fiber post group luted with resin-cement (p = 0.008). However, the differences between the undercut group and the groups with flowable composite as the luting agent were not significant (p = 0.068, p = 0.557). Adhesive failure was more frequent in the fiber post groups.

Conclusions

Although the composite post with undercutting showed the greatest resistance to dislodgement, fiber posts cemented with flowable composite resin provided acceptable results in terms of retentive strength and fracture mode.

Citations

Citations to this article as recorded by  
  • Mechanical Properties and Clinical Success of Intracanal Posts in Primary Maxillary Anterior Teeth: A Systematic Review and Meta-analysis
    Selvakumar Haridoss, MS Muthu, Kavitha Swaminathan, Yamuna Shanmugam, Aksshaya Raghu, Krishnapillai Chandrababu Vignesh, Sunil Babu Kotha
    International Journal of Clinical Pediatric Dentistry.2024; 16(S3): S293.     CrossRef
  • Comparison of shear bond strength of different types of intracanal posts in restoring extensively damaged primary anterior teeth
    Shabnam Asghari Mollabashi, Shima Nourmohamadi, Afrooz Nakhostin
    Journal of Dental Research, Dental Clinics, Dental Prospects.2024; 18(2): 95.     CrossRef
  • Effects of glass fibers reinforced and non-reinforced composite resin on fracture behavior of severely destructed primary incisors and restored with post and core system
    Rizk El Agamy
    The Saudi Dental Journal.2024; 36(3): 451.     CrossRef
  • Evaluation of the Effects of Different Types of Resin Cement Systems on the Push-Out Bond Strength of the Fiber Post to Intracanal Dentin in Anterior Primary Teeth
    Ali Nozari, Boshra Rasoolzade, Zahra Jowkar, Seyed Ahmadreza Hamidi, Mohammad Jowkar, Murilo Baena Lopes
    International Journal of Dentistry.2023; 2023: 1.     CrossRef
  • Comparison of the Pull-Out Resistance of Grossly Decayed Primary Anterior Teeth Restored With Two Different Intracanal Posts: An In Vitro Study
    Ayham Hijaz, Mohamed K Altinawi, Imad Katbeh, Eyad Gergos, Gharawi Alhamzah
    Cureus.2023;[Epub]     CrossRef
  • Comparison of fracture resistance of primary incisor teeth restored with glass fiber post and reversed-oriented metal post – an in vitro study
    Hamideh Barghi, Samira Sharifi
    Dental Research Journal.2023;[Epub]     CrossRef
  • Clinical and radiographic comparative study to evaluate the efficacy of restoring destroyed primary incisors using two different techniques—A pilot study
    Seba Ibrahim, Abdul Wahab Nourallah
    Clinical and Experimental Dental Research.2020; 6(5): 537.     CrossRef
  • Coronal Microleakage of Teeth Restored with Cast Posts and Cores Cemented with Four Different Luting Agents after Thermocycling
    Maryam Mohajerfar, Kaveh Nadizadeh, Tabasom Hooshmand, Elaheh Beyabanaki, Hamid Neshandar Asli, Siamak Sabour
    Journal of Prosthodontics.2019;[Epub]     CrossRef
  • Evaluation of the effect of different post materials and adhesive systems on the bonding strength of short‐post technique for primary teeth
    Nihal Beldüz Kara, Tunahan Kanyilmaz, Soner Çankaya, Cankat Kara
    International Journal of Paediatric Dentistry.2018; 28(2): 239.     CrossRef
  • Effect of ultrasonic tip designs on intraradicular post removal
    Anny Carine Barros Aguiar, Daniely Amorim de Meireles, André Augusto Franco Marques, Emílio Carlos Sponchiado Júnior, Angela Delfina Bitencourt Garrido, Lucas da Fonseca Roberti Garcia
    Restorative Dentistry & Endodontics.2014; 39(4): 265.     CrossRef
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Influence of operator's experience level on lifespan of the WaveOne Primary file in extracted teeth
Abdulrahman Mohammed Saleh, Saeid Tavanafar, Pouyan Vakili-Gilani, Noor Jamal Al Sammerraie, Faahim Rashid
Restor Dent Endod 2013;38(4):222-226.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.222
AbstractAbstract PDFPubReaderePub
Objectives

The aim of this study was to assess the influence of operator experience level on the lifespan of the WaveOne Primary file (Dentsply Maillefer, Ballaigues, Switzerland) in extracted teeth.

Materials and Methods

Moderately curved canals of extracted maxillary and mandibular molars were randomly distributed into 2 groups: experienced and inexperienced operators. Ten files were allocated to each group (n = 10). Each canal was prepared until the working length was reached, and the same file was used to prepare additional canals until it separated. The number of canals prepared before file separation was recorded. The fragment length of each file was measured, and the location of the fragment in the canal was determined. Data were statistically analysed using the independent 2-sample t-test.

Results

The 2 operators prepared a total of 324 moderately curved canals of maxillary and mandibular molars. There was no significant intergroup difference in the mean number of canals prepared (p = 0.27). The average lifespan of the WaveOne Primary file was 17.1 and 15.3 canals, and the longest lifespan was 25 and 20 canals, when used by experienced and inexperienced operators, respectively. There were no statistically significant intergroup differences in separated fragment length and location.

Conclusions

Within the limitations of this study, operator experience level appears to have no effect on the lifespan of the WaveOne Primary file in preparation of moderately curved canals. Single teeth with multiple canals can be prepared safely even by a novice operator by using a single file.

Citations

Citations to this article as recorded by  
  • Microstructural, microchemical, and mechanical changes associated with the clinical reuse of two nickel–titanium endodontic instruments
    Felipe Augusto Restrepo-Restrepo, Viviana Andrea Holguín-Vásquez, Syldana Julieth Cañas-Jiménez, Paula Andrea Villa-Machado, Sara Ochoa-Soto, Claudia Patricia Ossa-Orozco, Sergio Iván Tobón-Arroyave
    Dental Research Journal.2021; 18(1): 48.     CrossRef
  • Fracture incidence of WaveOne Gold files: a prospective clinical study
    C. S. P. Bueno, D. P. Oliveira, R. A. Pelegrine, C. E. Fontana, D. G. P. Rocha, J. L. Gutmann, C. E. S. Bueno
    International Endodontic Journal.2020; 53(9): 1192.     CrossRef
  • Current Assessment of Reciprocation in Endodontic Preparation: A Comprehensive Review—Part II: Properties and Effectiveness
    Gianluca Plotino, Hany Mohamed Aly Ahmed, Nicola Maria Grande, Stephen Cohen, Frédéric Bukiet
    Journal of Endodontics.2015; 41(12): 1939.     CrossRef
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A preliminary report on histological outcome of pulpotomy with endodontic biomaterials vs calcium hydroxide
Ali Nosrat, Ali Peimani, Saeed Asgary
Restor Dent Endod 2013;38(4):227-233.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.227
AbstractAbstract PDFPubReaderePub
Objectives

The purpose of the study was to evaluate human dental pulp response to pulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calcium enriched mixture (CEM) cement.

Materials and Methods

A total of nine erupted third molars were randomly assigned to each pulpotomy group. The same clinician performed full pulpotomies and coronal restorations. The patients were followed clinically for six months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulp inflammation, and calcified bridge formation.

Results

All patients were free of clinical signs/symptoms of pulpal/periradicular diseases during the follow up period. In CH group, one tooth had necrotic radicular pulp; other two teeth in this group had vital uninflamed pulps with complete dentinal bridge formation. In CEM cement and MTA groups all teeth had vital uninflamed radicular pulps. A complete dentinal bridge was formed beneath CEM cement and MTA in all roots. Odontoblast-like cells were present beneath CEM cement and MTA in all samples.

Conclusions

This study revealed that CEM cement and MTA were reliable endodontic biomaterials in full pulpotomy treatment. In contrast, the human dental pulp response to CH might be unpredictable.

Citations

Citations to this article as recorded by  
  • A meta‐analysis of calcium silicate‐based cements and calcium hydroxide as promoters of hard tissue bridge formation
    Emmanuel J. N. L. Silva, Karem P. Pinto, Fernanda N. S. J. Riche, Maristela G. H. Carestiato, Jorge N. R. Martins, Henry F. Duncan, Marco A. Versiani, Gustavo De‐Deus
    International Endodontic Journal.2025;[Epub]     CrossRef
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    Saeed Asgary, Mahtab Aram, Mahta Fazlyab
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    Saeed Asgary, Ali Nosrat
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  • Surgical management of a failed internal root resorption treatment: a histological and clinical report
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  • Effect of Mineral Trioxide Aggregate Surface Treatments on Morphology and Bond Strength to Composite Resin
    Joo-Hee Shin, Ji-Hyun Jang, Sang Hyuk Park, Euiseong Kim
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Effects of dentin moisture on the push-out bond strength of a fiber post luted with different self-adhesive resin cements
Sevinç Aktemur Türker, Emel Uzunoğlu, Zeliha Yılmaz
Restor Dent Endod 2013;38(4):234-240.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.234
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated the effects of intraradicular moisture on the pushout bond strength of a fibre post luted with several self-adhesive resin cements.

Materials and Methods

Endodontically treated root canals were treated with one of three luting cements: (1) RelyX U100, (2) Clearfil SA, and (3) G-Cem. Roots were then divided into four subgroups according to the moisture condition tested: (I) dry: excess water removed with paper points followed by dehydration with 95% ethanol, (II) normal moisture: canals blot-dried with paper points until appearing dry, (III) moist: canals dried by low vacuum using a Luer adapter, and (IV) wet: canals remained totally flooded. Two 1-mm-thick slices were obtained from each root sample and bond strength was measured using a push-out test setup. The data were analysed using a two-way analysis of variance and the Bonferroni post hoc test with p = 0.05.

Results

Statistical analysis demonstrated that moisture levels had a significant effect on the bond strength of luting cements (p < 0.05), with the exception of G-Cem. RelyX U100 displayed the highest bond strength under moist conditions (III). Clearfil SA had the highest bond strength under normal moisture conditions (II). Statistical ranking of bond strength values was as follows: RelyX U100 > Clearfil SA > G-Cem.

Conclusions

The degree of residual moisture significantly affected the adhesion of luting cements to radicular dentine.

Citations

Citations to this article as recorded by  
  • Push-Out Bond Strength of Different Luting Cements Following Post Space Irrigation with 2% Chitosan: An In Vitro Study
    Shimaa Rifaat, Ahmed Rahoma, Hind Muneer Alharbi, Sawsan Jamal Kazim, Shrouq Ali Aljuaid, Basmah Omar Alakloby, Faraz A. Farooqi, Noha Taymour
    Prosthesis.2025; 7(1): 18.     CrossRef
  • Dentin bond strength of resin luting agents under a simulated intra-oral environment
    Takashi Washino, Hanemi Tsuruta, Masaomi Ikeda, Michael F. Burrow, Toru Nikaido
    Asian Pacific Journal of Dentistry.2024; 24(2): 13.     CrossRef
  • Effects of a relined fiberglass post with conventional and self-adhesive resin cement
    Wilton Lima dos Santos Junior, Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Luís Roberto Marcondes Martins
    Restorative Dentistry & Endodontics.2024;[Epub]     CrossRef
  • Effect of dentin moisture on the adhesive properties of luting fiber posts using adhesive strategies
    Renata Terumi JITUMORI, Rafaela Caroline RODRIGUES, Alessandra REIS, João Carlos GOMES, Giovana Mongruel GOMES
    Brazilian Oral Research.2023;[Epub]     CrossRef
  • Influence of different intraradicular chemical pretreatments on the bond strength of adhesive interface between dentine and fiber post cements: A systematic review and network meta‐analysis
    Ana Luiza Barbosa Jurema, Ayla Macyelle de Oliveira Correia, Manuela da Silva Spinola, Eduardo Bresciani, Taciana Marco Ferraz Caneppele
    European Journal of Oral Sciences.2022;[Epub]     CrossRef
  • SELF ADEZİV REZİN SİMANLAR / SELF ADHESIVE RESIN CEMENTS
    Kübra AMAÇ, Engin ESENTÜRK, Bilge TURHAN BAL
    Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2022; : 1.     CrossRef
  • Postspace pretreatment with 17% ethylenediamine tetraacetic acid, 7% maleic acid, and 1% phytic acid on bond strength of fiber posts luted with a self-adhesive resin cement
    PriyaC Yadav, Ramya Raghu, Ashish Shetty, Subhashini Rajasekhara
    Journal of Conservative Dentistry.2021; 24(6): 558.     CrossRef
  • Development and characterization of biological bovine dentin posts
    Alice Gonçalves Penelas, Eduardo Moreira da Silva, Laiza Tatiana Poskus, Amanda Cypriano Alves, Isis Ingrid Nogueira Simões, Viviane Hass, José Guilherme Antunes Guimarães
    Journal of the Mechanical Behavior of Biomedical Materials.2019; 92: 197.     CrossRef
  • Evaluation of the influence of time and concentration of sodium hypochlorite on the bond strength of glass fibre post
    Beau Knight, Robert M. Love, Roy George
    Australian Endodontic Journal.2018; 44(3): 267.     CrossRef
  • Test methods for bond strength of glass fiber posts to dentin: A review
    F. C. Dos Santos, M. D. Banea, H. L. Carlo, S. De Barros
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  • Is the bonding of self-adhesive cement sensitive to root region and curing mode?
    Thaynara Faelly BOING, Giovana Mongruel GOMES, João Carlos GOMES, Alessandra REIS, Osnara Maria Mongruel GOMES
    Journal of Applied Oral Science.2017; 25(1): 2.     CrossRef
  • A Twofold Comparison between Dual Cure Resin Modified Cement and Glass Ionomer Cement for Orthodontic Band Cementation
    Hanaa El Attar, Omnia Elhiny, Ghada Salem, Ahmed Abdelrahman, Mazen Attia
    Open Access Macedonian Journal of Medical Sciences.2016; 4(4): 695.     CrossRef
  • Shear bond strengths of various self-adhesive resin cements between bovine dentin and 4 types of adherends
    Ah-Jin Kim, Da-Ryeong Park, Seunghan Oh, Ji-Myung Bae
    Korean Journal of Dental Materials.2015; 42(4): 365.     CrossRef
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Close layer
Effect of Epigallocatechin Gallate on shear bond strength of composite resin to bleached enamel: an in vitro study
Zahra Khamverdi, Loghman Rezaei-Soufi, Shahin Kasraei, Negin Ronasi, Shiva Rostami
Restor Dent Endod 2013;38(4):241-247.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.241
AbstractAbstract PDFPubReaderePub
Objectives

The aim of this study was to determine the effect of epigallocatechin gallate (EGCG) on the shear bond strength of composite resin to bleached enamel.

Materials and Methods

Ninety enamel surfaces of maxillary incisors were randomly divided into 9 groups as follows: G1: control (no bleaching); G2: bleaching; G3: bleaching and storage for seven days; G4 - 6: bleaching and application of 600, 800 and 1,000 µmol of EGCG-containing solution for 10 minutes, respectively; G7 - 9: bleaching and application of 600, 800 and 1,000 µmol of EGCG-containing solution for 20 minutes, respectively. The specimens were bleached with 30% hydrogen peroxide gel and a composite resin cylinder was bonded on each specimen using a bonding agent. Shear bond strength of the samples were measured in MPa. Data was analyzed using the two-way ANOVA and Tukey HSD tests (α = 0.05).

Results

The maximum and minimum mean shear bond strength values were observed in G1 and G2, respectively. Time and concentration of EGCG showed no significant effects on bond strength of the groups (p > 0.05). Multiple comparison of groups did not reveal any significant differences between the groups except for G2 and all the other groups (p < 0.05).

Conclusions

There is a significant decrease in bond strength of composite resin to enamel immediately after bleaching. A delay of one week before bonding and the use of EGCG increased bond strength of composite resin to bleached enamel.

Citations

Citations to this article as recorded by  
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    Rodrigo Chiles PEREIRA, Letícia Vasconcelos Silva de SOUZA, Matheus KURY, Iago César Ribeiro Teles MATOS, Reginna Vyctória da Trindade Souza de Melo CARNEIRO, Sandrine Bittencourt BERGER, Vanessa CAVALLI
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    F Ghorbani, SH Pourhaghani, H Heshmat, SH Jalalian, MJ Kharazifard
    Journal of Research in Dental and Maxillofacial Sciences.2022; 7(2): 62.     CrossRef
  • Effect of nonthermal atmospheric plasma, grape seed extract, and bromelain on immediate bonding of composite to bleached and microabraded surfaces
    MayanaAameena Banu, Nagesh Bolla, Sravanthi Tammineedi, Sayesh Vemuri, RamChowdary Basam, AnilKumar Ganapati
    Journal of Conservative Dentistry.2022; 25(1): 42.     CrossRef
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    Syarifah Nadhira Assyafira Al-Habsyi, Kun Ismiyatin, Galih Sampoerno
    Conservative Dentistry Journal.2021; 11(1): 42.     CrossRef
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    Juana Rodríguez‐Barragué, Joanna Vola‐Gelmini, Marcel Skuras‐Siedemburg, José Alejandro Rivera‐Gonzaga, Carlos Enrique Cuevas‐Suarez
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  • DİŞ BEYAZLATMA İŞLEMİNİN LİTYUM DİSİLİKAT SERAMİĞİN BAĞLANMA DAYANIMINA ETKİSİ
    Merve YILDIRAK, Rıfat GÖZNELİ
    Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2020; : 1.     CrossRef
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    Anshu Minocha, Ashu K. Gupta, Alisha Dhingra, Nayantara Sen
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    Pedro H.C. Oliveira, Alessandra Cassoni, Aldo Brugnera, Ilana P. Tenório, José A. Rodrigues
    Photomedicine and Laser Surgery.2017; 35(10): 530.     CrossRef
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    Payal Singh, Rajni Nagpal, Udai Pratap Singh
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    Renata C. A. Schwertner, Joyce S. Y. Leoncio, Alessandro Schwertner, Ricardo D. Guiraldo, Murilo B. Lopes, Hellen C. De Carvalho, Alcides Gonini-Júnior, Sandrine B. Berger
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  • 18 Crossref
Close layer
Washout resistance of fast-setting pozzolan cement under various root canal irrigants
Ga-Yeon Jang, Su-Jung Park, Seok-Mo Heo, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
Restor Dent Endod 2013;38(4):248-252.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.248
AbstractAbstract PDFPubReaderePub
Objectives

Fast-setting pozzolan cement (Endocem, Maruchi) was recently developed. The aim of this study was to investigate the effects of various root canal irrigants on the washout of Endocem in comparison to the previously marketed mineral trioxide aggregate (ProRoot; Dentsply) in a furcal perforation model.

Materials and Methods

ProRoot and Endocem were placed into acrylic molds on moist Oasis. Each mold was then immediately exposed to either physiologic saline, 2.5% sodium hypochlorite (NaOCl), or 2% chlorhexidine (CHX) under gentle shaking for five minutes. Washout testing was performed by scoring scanning electron microscope (SEM) images.

Results

Endocem exhibited higher washout resistance compared to ProRoot, especially in the NaOCl group.

Conclusions

These results suggest that Endocem can be considered a useful repair material for furcal perforation, especially in a single-visit scenario.

Citations

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  • Stereomicroscopic Evaluation of Sealing Ability of Three Different Furcal Perforation Repair Materials: An In vitro Study
    Sriparna De, N Sathyajith Naik, Shivangi Sharma, Pallavi Vashisth, Rasleen Dua, Priya Maheshwari
    Contemporary Clinical Dentistry.2024; 15(4): 259.     CrossRef
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    Hoda Mohamed ELNAWAWY, Muralithran Govindan KUTTY, Noor Azlin YAHYA, Noor Hayaty ABU KASIM, Paul Roy COOPER, Josette CAMILLERI, Hany Mohamed Aly AHMED
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    Joanna Falkowska, Tomasz Chady, Włodzimierz Dura, Agnieszka Droździk, Małgorzata Tomasik, Ewa Marek, Krzysztof Safranow, Mariusz Lipski
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    Dohyun Kim, Hyunjung Lee, Minsun Chung, Sunil Kim, Minju Song, Euiseong Kim
    Clinical Oral Investigations.2020; 24(1): 247.     CrossRef
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    Jae-Sung Kwon, Myung-Jin Lee, Ji-Young Kim, Dohyun Kim, Jeong-Hyun Ryu, Sungil Jang, Kwang-Mahn Kim, Chung-Ju Hwang, Sung-Hwan Choi, Jinkee Hong
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    Hacer Aksel, Selen Küçükkaya Eren, Sevinc Askerbeyli Õrs, Eda Karaismailoğlu
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    Emmanuel João Nogueira Leal Silva, Nancy Kudsi Carvalho, Marta Reis da Costa Labanca Guberman, Marina Prado, Plinio Mendes Senna, Erick M. Souza, Gustavo De-Deus
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    Yeon‐Jee Yoo, Seung‐Ho Baek, Kee‐Yeon Kum, Won‐Jun Shon, Kyung‐Mi Woo, WooCheol Lee
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    Jing-Ling Che, Jae-Hwan Kim, Seon-Mi Kim, Nam-ki Choi, Hyun-Joo Moon, Moon-Jin Hwang, Ho-Jun Song, Yeong-Joon Park
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    Youngjune Jang, Minju Song, Il-Sang Yoo, Yunjung Song, Byoung-Duck Roh, Euiseong Kim
    Journal of Endodontics.2015; 41(8): 1201.     CrossRef
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    Kyoung-A KIM, Yeon-Mi YANG, Young-Sun KWON, Yun-Chan HWANG, Mi-Kyung YU, Kyung-San MIN
    Dental Materials Journal.2015; 34(4): 432.     CrossRef
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    William N. Ha, Dale P. Bentz, Bill Kahler, Laurence J. Walsh
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  • A Randomized Controlled Study of the Use of ProRoot Mineral Trioxide Aggregate and Endocem as Direct Pulp Capping Materials
    Minju Song, Minji Kang, Hyeon-Cheol Kim, Euiseong Kim
    Journal of Endodontics.2015; 41(1): 11.     CrossRef
  • Physical properties and biological/odontogenic effects of an experimentally developed fast-setting α-tricalcium phosphate-based pulp capping material
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    Joo-Hee Shin, Ji-Hyun Jang, Sang Hyuk Park, Euiseong Kim
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  • 15 Crossref
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Case Reports
Endodontic treatment of maxillary lateral incisors with anatomical variations
Moon-Hwan Lee, Jung-Hong Ha, Myoung-Uk Jin, Young-Kyung Kim, Sung-Kyo Kim
Restor Dent Endod 2013;38(4):253-257.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.253
AbstractAbstract PDFPubReaderePub

Maxillary lateral incisors usually exhibit a single root with a single canal. However, maxillary lateral incisor teeth with unusual morphology of root canal system are frequently reported. These cases of variable root canal anatomy can be treated well by nonsurgical endodontic methods. A detailed description of root canal morphology is fundamental for successful endodontic treatment. Treatment using an operating microscope, radiographs from different angles, and cone-beam computerized tomography (CBCT) can produce more predictable endodontic outcomes.

Citations

Citations to this article as recorded by  
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    Pujan Kranti Kayastha, Merina Shakya, Laxman Poudel
    Journal of Interdisciplinary Dentistry.2022; 12(1): 32.     CrossRef
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Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report
Cyril Villat, Brigitte Grosgogeat, Dominique Seux, Pierre Farge
Restor Dent Endod 2013;38(4):258-262.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.258
AbstractAbstract PDFPubReaderePub

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

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Open Lecture on Statistics
Statistical notes for clinical researchers: Understanding standard deviations and standard errors
Hae-Young Kim
Restor Dent Endod 2013;38(4):263-265.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.263
PDFPubReaderePub

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Reader's Forum
Light curing of dual cure resin cement
Hoon-Sang Chang
Restor Dent Endod 2013;38(4):266-267.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.266
PDFPubReaderePub

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