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Research Articles
Effects of calcium silicate cements on neuronal conductivity
Derya Deniz-Sungur, Mehmet Ali Onur, Esin Akbay, Gamze Tan, Fügen Daglı-Comert, Taner Cem Sayın
Restor Dent Endod 2022;47(2):e18.   Published online March 7, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e18
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated alterations in neuronal conductivity related to calcium silicate cements (CSCs) by investigating compound action potentials (cAPs) in rat sciatic nerves.

Materials and Methods

Sciatic nerves were placed in a Tyrode bath and cAPs were recorded before, during, and after the application of test materials for 60-minute control, application, and recovery measurements, respectively. Freshly prepared ProRoot MTA, MTA Angelus, Biodentine, Endosequence RRM-Putty, BioAggregate, and RetroMTA were directly applied onto the nerves. Biopac LabPro version 3.7 was used to record and analyze cAPs. The data were statistically analyzed.

Results

None of the CSCs totally blocked cAPs. RetroMTA, Biodentine, and MTA Angelus caused no significant alteration in cAPs (p > 0.05). Significantly lower cAPs were observed in recovery measurements for BioAggregate than in the control condition (p < 0.05). ProRoot MTA significantly but transiently reduced cAPs in the application period compared to the control period (p < 0.05). Endosequence RRM-Putty significantly reduced cAPs.

Conclusions

Various CSCs may alter cAPs to some extent, but none of the CSCs irreversibly blocked them. The usage of fast-setting CSCs during apexification or regeneration of immature teeth seems safer than slow-setting CSCs due to their more favorable neuronal effects.

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Comparative analysis of bond strength to root dentin and compression of bioceramic cements used in regenerative endodontic procedures
Maykely Naara Morais Rodrigues, Kely Firmino Bruno, Ana Helena Gonçalves de Alencar, Julyana Dumas Santos Silva, Patrícia Correia de Siqueira, Daniel de Almeida Decurcio, Carlos Estrela
Restor Dent Endod 2021;46(4):e59.   Published online November 9, 2021
DOI: https://doi.org/10.5395/rde.2021.46.e59
AbstractAbstract PDFPubReaderePub
Objectives

This study compared the Biodentine, MTA Repair HP, and Bio-C Repair bioceramics in terms of bond strength to dentin, failure mode, and compression.

Materials and Methods

Fifty-four slices obtained from the cervical third of 18 single-rooted human mandibular premolars were randomly distributed (n = 18). After insertion of the bioceramic materials, the push-out test was performed. The failure mode was analyzed using stereomicroscopy. Another set of cylindrically-shaped bioceramic samples (n = 10) was prepared for compressive strength testing. The normality of data distribution was analyzed using the Shapiro-Wilk test. The Kruskal-Wallis and Friedman tests were used for the push-out test data, while compressive strength was analyzed with analysis of variance and the Tukey test, considering a significance level of 0.05.

Results

Biodentine presented a higher median bond strength value (14.79 MPa) than MTA Repair HP (8.84 MPa) and Bio-C Repair (3.48 MPa), with a significant difference only between Biodentine and Bio-C Repair. In the Biodentine group, the most frequent failure mode was mixed (61%), while in the MTA Repair HP and Bio-C Repair groups, it was adhesive (94% and 72%, respectively). Biodentine showed greater resistance to compression (29.59 ± 8.47 MPa) than MTA Repair HP (18.68 ± 7.40 MPa) and Bio-C Repair (19.96 ± 3.96 MPa) (p < 0.05).

Conclusions

Biodentine showed greater compressive strength than MTA Repair HP and Bio-C Repair, and greater bond strength than Bio-C Repair. The most frequent failure mode of Biodentine was mixed, while that of MTA Repair HP and Bio-C Repair was adhesive.

Citations

Citations to this article as recorded by  
  • Comparación de la resistencia compresiva entre el Agregado Trióxido Mineral y BiodentineTM en perforaciones de furca de molares inferiores permanentes
    Jheymy Gerardo Huatuco-Granda, John Paul Torres-Navarro, Rosa Josefina Roncal-Espinoza
    Revista Facultad de Odontología.2024;[Epub]     CrossRef
  • Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
    Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
    Restorative Dentistry & Endodontics.2023;[Epub]     CrossRef
  • Evaluation the Marginal Adaptation for the Bio C Repair and Other Root end Filling Material by Using Scanning Electron Microscope (A Comparative In Vitro Study)
    Fatimah HAMADHİ, Zainab M.
    Cumhuriyet Dental Journal.2023; 26(3): 261.     CrossRef
  • Dentin Bond Strength of Calcium Silicate-Based Materials: A Systematic Review of In Vitro Studies
    Natalia Radulica, José Luis Sanz, Adrián Lozano
    Applied Sciences.2023; 14(1): 104.     CrossRef
  • Evaluation Of The Push-out Bond Strength Of The Bio-C Repair And Compare It With The Mineral Trioxide Aggregate And Amalgam When Used As Root-end Filling Material
    Fatimah R. Hammadi, Zainab M Abdul-Ameer
    Dental Hypotheses.2023; 14(2): 62.     CrossRef
  • Effect of different root canal irrigants on push-out bond strength of two novel root-end filling materials
    Nada Omar, Rasha M. Abdelraouf, Tamer M. Hamdy
    BMC Oral Health.2023;[Epub]     CrossRef
  • Effect of irrigation systems on the bond strength of calcium-silicate-based cement used as pulp barrier in regenerative endodontic treatment
    Cihan Hascizmeci, Burak Buldur
    Journal of Adhesion Science and Technology.2023; 37(23): 3393.     CrossRef
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Case Report
Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report
Cyril Villat, Brigitte Grosgogeat, Dominique Seux, Pierre Farge
Restor Dent Endod 2013;38(4):258-262.   Published online November 12, 2013
DOI: https://doi.org/10.5395/rde.2013.38.4.258
AbstractAbstract PDFPubReaderePub

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

Citations

Citations to this article as recorded by  
  • How Does Ethylenediaminetetraacetic Acid Irrigation Affect Biodentine? A Multimethod Ex Vivo Study
    Katarzyna Dąbrowska, Aleksandra Palatyńska-Ulatowska, Leszek Klimek
    Materials.2024; 17(6): 1230.     CrossRef
  • Evaluation of Biodentine Tricalcium Silicate-Based Cement after Chlorhexidine Irrigation
    Katarzyna Dąbrowska, Aleksandra Palatyńska-Ulatowska, Leszek Klimek
    Applied Sciences.2024; 14(19): 8702.     CrossRef
  • Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study
    Monthip Wannakajeepiboon, Chankhrit Sathorn, Chatvadee Kornsuthisopon, Busayarat Santiwong, Thanakorn Wasanapiarnpong, Pairoj Linsuwanont
    BMC Oral Health.2023;[Epub]     CrossRef
  • Protección pulpar directa y posterior apexogénesis. Informe de un caso clínico / Direct pulp capping followed by apexogenesis. A clinical case report
    Osvaldo Zmener, Ana C. Boetto
    Revista de la Asociación Odontológica Argentina.2022;[Epub]     CrossRef
  • The Effect of Irrigation with Citric Acid on Biodentine Tricalcium Silicate-Based Cement: SEM-EDS In Vitro Study
    Katarzyna Dąbrowska, Aleksandra Palatyńska-Ulatowska, Leszek Klimek
    Materials.2022; 15(10): 3467.     CrossRef
  • The Immunomodulatory and Regenerative Effect of Biodentine™ on Human THP‐1 Cells and Dental Pulp Stem Cells: In Vitro Study
    Duaa Abuarqoub, Nazneen Aslam, Rand Zaza, Hanan Jafar, Suzan Zalloum, Renata Atoom, Walhan Alshaer, Mairvat Al-Mrahleh, Abdalla Awidi, Bruna Sinjari
    BioMed Research International.2022;[Epub]     CrossRef
  • Biodentine: Material of choice for apexification
    Himanshu Aeran, Mahema Sharma, Avantika Tuli
    International Journal of Oral Health Dentistry.2021; 7(1): 54.     CrossRef
  • Minimal Intervention in Dentistry: A Literature Review on Biodentine as a Bioactive Pulp Capping Material
    Naji Ziad Arandi, Mohammad Thabet, Mona Abbassy
    BioMed Research International.2021;[Epub]     CrossRef
  • Biodentine Pulpotomies on Permanent Traumatized Teeth with Complicated Crown Fractures
    Léa Haikal, Beatriz Ferraz dos Santos, Duy-Dat Vu, Marina Braniste, Basma Dabbagh
    Journal of Endodontics.2020; 46(9): 1204.     CrossRef
  • Influence of sodium hypochlorite and ultrasounds on surface features and chemical composition of Biodentine tricalcium silicate-based material
    Aleksandra PALATYŃSKA-ULATOWSKA, Katarzyna BUŁA, Leszek KLIMEK
    Dental Materials Journal.2020; 39(4): 587.     CrossRef
  • Effects of two fast-setting pulp-capping materials on cell viability and osteogenic differentiation in human dental pulp stem cells: An in vitro study
    Yan Sun, Jun Liu, Tao Luo, Ya Shen, Ling Zou
    Archives of Oral Biology.2019; 100: 100.     CrossRef
  • Healing Capacity of Autologous Bone Marrow–derived Mesenchymal Stem Cells on Partially Pulpotomized Dogs' Teeth
    Mona H. El-Zekrid, Salah H. Mahmoud, Fawzy A. Ali, Mohamed E. Helal, Mohammed E. Grawish
    Journal of Endodontics.2019; 45(3): 287.     CrossRef
  • Large Periapical or Cystic Lesions in Association with Roots Having Open Apices Managed Nonsurgically Using 1-step Apexification Based on Platelet-rich Fibrin Matrix and Biodentine Apical Barrier: A Case Series
    Sarang Sharma, Vivek Sharma, Deepak Passi, Dhirendra Srivastava, Shibani Grover, Shubha Ranjan Dutta
    Journal of Endodontics.2018; 44(1): 179.     CrossRef
  • Microleakage and Shear Bond Strength of Biodentine at Different Setting Time
    Yong Ho Song, Nanyoung Lee, Sangho Lee, Myeongkwan Jih
    THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY.2018; 45(3): 344.     CrossRef
  • Biodentine™ material characteristics and clinical applications: a 3 year literature review and update
    S. Rajasekharan, L. C. Martens, R. G. E. C. Cauwels, R. P. Anthonappa
    European Archives of Paediatric Dentistry.2018; 19(1): 1.     CrossRef
  • Case Report: Immediate pain relief after partial pulpotomy of cariously exposed young permanent molar using mineral trioxide aggregate and root maturation, with two years follow-up
    Passant Nagi, Nevine Waly, Adel Elbardissy, Mohammed Khalifa
    F1000Research.2018; 7: 1616.     CrossRef
  • Factors affecting the outcomes of direct pulp capping using Biodentine
    Mariusz Lipski, Alicja Nowicka, Katarzyna Kot, Lidia Postek-Stefańska, Iwona Wysoczańska-Jankowicz, Lech Borkowski, Paweł Andersz, Anna Jarząbek, Katarzyna Grocholewicz, Ewa Sobolewska, Krzysztof Woźniak, Agnieszka Droździk
    Clinical Oral Investigations.2018; 22(5): 2021.     CrossRef
  • Mineral trioxide aggregate and other bioactive endodontic cements: an updated overview – part I: vital pulp therapy
    M. Parirokh, M. Torabinejad, P. M. H. Dummer
    International Endodontic Journal.2018; 51(2): 177.     CrossRef
  • Effect of iRoot Fast Set root repair material on the proliferation, migration and differentiation of human dental pulp stem cells in vitro
    Yan Sun, Tao Luo, Ya Shen, Markus Haapasalo, Ling Zou, Jun Liu, Gianpaolo Papaccio
    PLOS ONE.2017; 12(10): e0186848.     CrossRef
  • Dislodgement resistance of calcium silicate‐based materials from root canals with varying thickness of dentine
    Ö. İ. Ulusoy, Y. N. Paltun, N. Güven, B. Çelik
    International Endodontic Journal.2016; 49(12): 1188.     CrossRef
  • Expression of Mineralization Markers during Pulp Response to Biodentine and Mineral Trioxide Aggregate
    Mariana O. Daltoé, Francisco Wanderley G. Paula-Silva, Lúcia H. Faccioli, Patrícia M. Gatón-Hernández, Andiara De Rossi, Léa Assed Bezerra Silva
    Journal of Endodontics.2016; 42(4): 596.     CrossRef
  • Biodentine Reduces Tumor Necrosis Factor Alpha–induced TRPA1 Expression in Odontoblastlike Cells
    Ikhlas A. El Karim, Maelíosa T.C. McCrudden, Mary K. McGahon, Tim M. Curtis, Charlotte Jeanneau, Thomas Giraud, Chris R. Irwin, Gerard J. Linden, Fionnuala T. Lundy, Imad About
    Journal of Endodontics.2016; 42(4): 589.     CrossRef
  • Coronal Pulpotomy Technique Analysis as an Alternative to Pulpectomy for Preserving the Tooth Vitality, in the Context of Tissue Regeneration: A Correlated Clinical Study across 4 Adult Permanent Molars
    Raji Viola Solomon, Umrana Faizuddin, Parupalli Karunakar, Grandhala Deepthi Sarvani, Sevvana Sree Soumya
    Case Reports in Dentistry.2015; 2015: 1.     CrossRef
  • A Review on Biodentine, a Contemporary Dentine Replacement and Repair Material
    Özlem Malkondu, Meriç Karapinar Kazandağ, Ender Kazazoğlu
    BioMed Research International.2014; 2014: 1.     CrossRef
  • The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report
    Günseli Güven Polat, Ceren Yıldırım, Özlem Martı Akgün, Ceyhan Altun, Didem Dinçer, Cansel Köse Özkan
    Restorative Dentistry & Endodontics.2014; 39(3): 230.     CrossRef
  • Biodentine-a novel dentinal substitute for single visit apexification
    Gurudutt Nayak, Mohammad Faiz Hasan
    Restorative Dentistry & Endodontics.2014; 39(2): 120.     CrossRef
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