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Research Article
Evaluation of softening ability of Xylene & Endosolv-R on three different epoxy resin based sealers within 1 to 2 minutes - an in vitro study
Pratima Ramakrishna Shenoi, Gautam Pyarelal Badole, Rajiv Tarachand Khode
Restor Dent Endod 2014;39(1):17-23.   Published online January 20, 2014
DOI: https://doi.org/10.5395/rde.2014.39.1.17
AbstractAbstract PDFPubReaderePub
Objectives

This study evaluated the efficacy of Endosolv-R and Xylene in softening epoxy resin based sealer after 1 to 2 min exposure.

Materials and Methods

Sixty Teflon molds (6 mm × 1.5 mm in inner diameter and depth) were equally divided into 3 groups of 20 each. AH 26 (Dentsply/De Trey), AH Plus (Dentsply/De Trey), Adseal (Meta-Biomed) were manipulated and placed in the molds allotted to each group and allowed to set at 37℃ in 100% humidity for 2 wk. Each group was further divided into 2 subgroups according to the solvents used, i.e. Xylene (Lobachemie) and Endosolv-R (Septodont). Specimens in each subgroup were exposed to respective solvents for 1 and 2 min and the corresponding Vicker's microhardness (HV) was assessed. Data was analysed by Mauchly's test and two-way analysis of variance (ANOVA) with repeated measures, and one-way ANOVA.

Results

Initial hardness was significantly different among the three sealers with AH Plus having the greatest and Adseal having the least. After 2 min, Xylene softened AH Plus and Adseal sealer to 11% and 25% of their initial microhardness, respectively (p < 0.001), whereas AH 26 was least affected, maintaining 89.4% of its initial microhardness. After 2 min, Endosolv-R softened AH 26, AH Plus and Adseal to 12.7, 5.6 and 8.1% of their initial microhardness, respectively (p < 0.001).

Conclusions

Endosolv-R was a significantly more effective short term softener for all the tested sealers after 2 min whereas Xylene was an effective short term softener against AH plus and Adseal but less effective against AH 26.

Citations

Citations to this article as recorded by  
  • Influência do protocolo de remoção de resíduos de cimentos à base de resina epóxi sobre a interface de adesão com o adesivo universal, utilizado na estratégia condiciona-e-lava
    Paulo Firmino Da Costa Neto, Mariana Bena Gelio, Elisângela Maria Pereira De Souza, Jardel Camilo do Carmo Monteiro, Adirson Jorge Júnior, Thais Piragine Leandrin, José Roberto Cury Saad, Milton Carlos Kuga
    Cuadernos de Educación y Desarrollo.2023; 15(5): 4802.     CrossRef
  • Comparative evaluation of the effectiveness of various solvents on dissolving efficacy of gutta percha- An in vitro- study
    Syed Manzoor Ul Haq Bukhari, Sheeeban Rashid, Rahil Bhat
    International Dental Journal of Student's Research.2023; 11(3): 121.     CrossRef
  • Bonding effects of cleaning protocols and time-point of acid etching on dentin impregnated with endodontic sealer
    Tatiane Miranda Manzoli, Joissi Ferrari Zaniboni, João Felipe Besegato, Flávia Angélica Guiotti, Andréa Abi Rached Dantas, Milton Carlos Kuga
    Restorative Dentistry & Endodontics.2022;[Epub]     CrossRef
  • Dissolving efficacy of xylene on epoxy resin-based and bioceramic-based root canal sealers
    Cindy Willie
    Scientific Dental Journal.2022; 6(1): 32.     CrossRef
  • A comparative evaluation of removal of gutta percha using two retreatment file system: An in vitro study
    Shruthi Mary Sunil, Balakrishnan Rajkumar, Vishesh Gupta, Akanksha Bhatt, Pragyan Paliwal
    IP Indian Journal of Conservative and Endodontics.2020; 5(2): 53.     CrossRef
  • Use of Resin Solvent as a Facilitator for Removal of Resin Composite Restoratives by Influencing their Mechanical Properties: Is this Possible?
    Inas A Elghandour
    Journal of Operative Dentistry & Endodontics.2019; 4(1): 1.     CrossRef
  • Effect of the calcium silicate‐based sealer removal protocols and time‐point of acid etching on the dentin adhesive interface
    Jéssika Mayhara Pereira Morais, Keli Regina Victorino, Wilfredo Gustavo Escalante‐Otárola, Keren Cristina Fagundes Jordão‐Basso, Regina Guenka Palma‐Dibb, Milton Carlos Kuga
    Microscopy Research and Technique.2018; 81(8): 914.     CrossRef
  • Persistence of Residues after Endodontic Retreatment related to the Obturation Technique and to the Solvent
    Matheus Coelho Bandéca, Milton C Kuga, Keren CF Jordão-Basso, Mateus R Tonetto, Arturo J Aranda-Garcia, Fernando A Vázquez-Garcia, Suellen NL Lima, Jardel C do Carmo Monteiro
    World Journal of Dentistry.2017; 8(1): 41.     CrossRef
  • Retreatability of different endodontic sealers using chemical solvents
    M.F. Obeid, M.M. Nagy
    Tanta Dental Journal.2015; 12(4): 286.     CrossRef
  • Do the Sealer Solvents Used Affect Apically Extruded Debris in Retreatment?
    Burhan Can Çanakçi, Ozgur Er, Asiye Dincer
    Journal of Endodontics.2015; 41(9): 1507.     CrossRef
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Original Article
Cytotoxicity of resin-based root canal sealer, adseal
Hee-Jung Kim, Seung-Ho Baek, Woo-Cheol Lee, Han-Soo Park, Kwang-Shik Bae
J Korean Acad Conserv Dent 2004;29(6):498-503.   Published online November 30, 2004
DOI: https://doi.org/10.5395/JKACD.2004.29.6.498
AbstractAbstract PDFPubReaderePub

The properties of ideal root canal sealers include the ability of sealing the total root canal system and no toxic effects to periradicular tissues. Cytotoxicity test using cell culture is a common screening method for evaluation of the biocompatibility of root canal sealers. The purpose of this study was to investigate the cytotoxic effect of newly developed resin-based sealer (Adseal 1, 2, and 3) comparing with those commercial resin-based sealers (AH26 and AH Plus), ZOE-based sealers (Tubliseal EWT, Pulp Canal Sealer EWT) and calcium hydroxide based sealer (Sealapex). An indirect contact test of cytotoxicity by agar diffusion was performed according to the international standard ISO 10993-5. L929 fibroblast cells were incubated at 37℃ in humidified 5% CO2-containing air atmosphere. The freshly mixed test materials were inserted into glass rings of internal diameter 5 mm and height 5 mm placed on the agar. After the 24 hrs incubation period, the decolorization zones around the test materials were assessed using an inverted microscope with a calibrated screen. A Decolorization Index was determined for each specimen. Adseal 1, 2, and 3 did not exert any cytotoxic effects, whereas AH26, AH Plus, Tubliseal EWT, Pulp Canal Sealer EWT, and Sealapex produced mild cytotoxicity.

Citations

Citations to this article as recorded by  
  • Cytotoxicity Comparison of Sure-seal root and Adseal Sealers on mouse fibroblast Cells:Invitro study
    Azam haddadikohsar, Mohammad shokrzade, Marjan Fallah, Fatemeh Shakeri
    journal of research in dental sciences.2024; 21(1): 46.     CrossRef
  • Antimicrobial efficacy of Kerr pulp canal sealer (EWT) in combination with 10% amoxicillin on Enterococcus faecalis: A confocal laser scanning microscopic study
    Madhureema De Sarkar, Kundabala Mala, Suchitra Shenoy Mala, Shama Prasada Kabekkodu, Srikant Natarajan, Neeta Shetty, Priyanka Madhav Kamath, Manuel Thomas
    F1000Research.2023; 12: 725.     CrossRef
  • Antimicrobial efficacy of Kerr pulp canal sealer (EWT) in combination with 10% amoxicillin on Enterococcus faecalis: A confocal laser scanning microscopic study
    Madhureema De Sarkar, Kundabala Mala, Suchitra Shenoy Mala, Shama Prasada Kabekkodu, Srikant Natarajan, Neeta Shetty, Priyanka Madhav Kamath, Manuel Thomas
    F1000Research.2023; 12: 725.     CrossRef
  • Cytotoxicity and Genotoxicity of Epoxy Resin-Based Root Canal Sealers before and after Setting Procedures
    Mijoo Kim, Marc Hayashi, Bo Yu, Thomas K. Lee, Reuben H. Kim, Deuk-won Jo
    Life.2022; 12(6): 847.     CrossRef
  • Biocompatibility and Bioactivity of Four Different Root Canal Sealers in Osteoblastic Cell Line MC3T3-El
    Nu-Ri Jun, Sun-Kyung Lee, Sang-Im Lee
    Journal of Dental Hygiene Science.2021; 21(4): 243.     CrossRef
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