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Endodontic biofilms: contemporary and future treatment options
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Yeon-Jee Yoo, Hiran Perinpanayagam, Soram Oh, A-Reum Kim, Seung-Hyun Han, Kee-Yeon Kum
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Restor Dent Endod 2019;44(1):e7. Published online January 31, 2019
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DOI: https://doi.org/10.5395/rde.2019.44.e7
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Abstract
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Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic procedures for intracanal disinfection. Both the disruption of biofilms and the killing of their bacteria are necessary to effectively treat apical periodontitis. Accordingly, a review of endodontic biofilm types, antimicrobial resistance mechanisms, and current and future therapeutic procedures for endodontic biofilm is provided.
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Anu Priya Guruswamy Pandian, Anil Kumar Ramachandran, Priyanka Kodaganallur Pitchumani, Blessy Mathai, Davis C Thomas Cureus.2025;[Epub] CrossRef - Self-Sacrificial Antibacterial Coating with Photothermal Response for Inhibiting Implant Infection
Jinglin Zhang, Aijian Cao, Lizhen Chen, Dongliang Huo, Jingxian Zhang, Langhuan Huang, Shaozao Tan ACS Applied Nano Materials.2024; 7(23): 26907. CrossRef - Biofilm in Endodontic Infection and its Advanced Therapeutic Options – An Updated Review
Srilekha Jayakumar, Dinesh Sridhar, Bindu M. John, Karthikeyan Arumugam, Prashanth Ponnusamy, Hema Pulidindi Journal of Pharmacy and Bioallied Sciences.2024; 16(Suppl 2): S1104. CrossRef - Analysis of the chemical interaction of polyhexanide with endodontic irrigants
Z. S. Zurab, Yu. A. Generalova, A. A. Kulikova, A. Yu. Umarov, F. V. Badalov, A. Wehbe, E. M. Kakabadze Endodontics Today.2024; 22(4): 319. CrossRef - In vitro evaluation of three engineered multispecies endodontic biofilms on a dentinal disk substrate
Wajih Hage, Dolla Karam Sarkis, Mireille Kallasy, May Mallah, Carla Zogheib Biomaterial Investigations in Dentistry.2023;[Epub] CrossRef - In vitro evaluation of enterococcus faecalis growth in different conditions on dentinal substrate
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A. P. Torres-Monjarás, R. Sánchez-Gutiérrez, B. Hernández-Castro, L. González-Baranda, D. L. Alvarado-Hernández, A. Pozos-Guillén, A. Muñoz-Ruiz, V. Méndez-González, R. González-Amaro, M. Vitales-Noyola Clinical Oral Investigations.2023; 27(6): 3139. CrossRef - Antimicrobial efficacy of Kerr pulp canal sealer (EWT) in combination with 10% amoxicillin on Enterococcus faecalis: A confocal laser scanning microscopic study
Madhureema De Sarkar, Kundabala Mala, Suchitra Shenoy Mala, Shama Prasada Kabekkodu, Srikant Natarajan, Neeta Shetty, Priyanka Madhav Kamath, Manuel Thomas F1000Research.2023; 12: 725. CrossRef - Antimicrobial efficacy of Kerr pulp canal sealer (EWT) in combination with 10% amoxicillin on Enterococcus faecalis: A confocal laser scanning microscopic study
Madhureema De Sarkar, Kundabala Mala, Suchitra Shenoy Mala, Shama Prasada Kabekkodu, Srikant Natarajan, Neeta Shetty, Priyanka Madhav Kamath, Manuel Thomas F1000Research.2023; 12: 725. CrossRef - Combined effect of electrical energy and graphene oxide on Enterococcus faecalis biofilms
Myung-Jin LEE, Mi-Ah KIM, Kyung-San MIN Dental Materials Journal.2023; 42(6): 844. CrossRef - Innovative Curved-Tip Reactor for Non-Thermal Plasma and Plasma-Treated Water Generation: Synergistic Impact Comparison with Sodium Hypochlorite in Dental Root Canal Disinfection
Raúl Arguello-Sánchez, Régulo López-Callejas, Benjamín Gonzalo Rodríguez-Méndez, Rogelio Scougall-Vilchis, Ulises Velázquez-Enríquez, Antonio Mercado-Cabrera, Rosendo Peña-Eguiluz, Raúl Valencia-Alvarado, Carlo Eduardo Medina-Solís Materials.2023; 16(22): 7204. CrossRef - Impact of antimicrobial photodynamic therapy on the bond-strength and penetration of endodontic sealers: A systematic review
Khalid H Almadi Photodiagnosis and Photodynamic Therapy.2023; 41: 103249. CrossRef - Apical periodontitis in mesiobuccal roots of maxillary molars: influence of anatomy and quality of root canal treatment, a CBCT study
Samantha Jannone Carrion, Marcelo Santos Coelho, Adriana de Jesus Soares, Marcos Frozoni Restorative Dentistry & Endodontics.2022;[Epub] CrossRef - Potential relationship between clinical symptoms and the root canal microbiomes of root filled teeth based on the next‐generation sequencing
Yajing Hou, Liu Wang, Lan Zhang, Xuelian Tan, Dingming Huang, Dongzhe Song International Endodontic Journal.2022; 55(1): 18. CrossRef - Efficacy of 6% Sodium Hypochlorite on Infectious Content of Teeth with Symptomatic Irreversible Pulpitis
Rodrigo Arruda-Vasconcelos, Marlos Barbosa-Ribeiro, Lidiane M. Louzada, Beatriz I.N. Lemos, Adriana de-Jesus-Soares, Caio C.R. Ferraz, José F.A. Almeida, Marina A. Marciano, Brenda P.F. A. Gomes Journal of Endodontics.2022; 48(2): 179. CrossRef - Specialized pro-resolving lipid mediators in endodontics: a narrative review
Davy Aubeux, Ove A. Peters, Sepanta Hosseinpour, Solène Tessier, Valérie Geoffroy, Fabienne Pérez, Alexis Gaudin BMC Oral Health.2021;[Epub] CrossRef - Effects of curcumin-mediated antimicrobial photodynamic therapy associated to different chelators against Enterococcus faecalis biofilms
Daniela Alejandra Cusicanqui Méndez, Maricel Rosario Cardenas Cuéllar, Victor Feliz Pedrinha, Evelyn Giuliana Velásquez Espedilla, Flaviana Bombarda de Andrade, Patrícia de Almeida Rodrigues, Thiago Cruvinel Photodiagnosis and Photodynamic Therapy.2021; 35: 102464. CrossRef - Effectiveness of D,L‐2‐hydroxyisocaproic acid (HICA) and alpha‐mangostin against endodontopathogenic microorganisms in a multispecies bacterial–fungal biofilm in anex vivotooth model
Warat Leelapornpisid, Lilyann Novak‐Frazer, Alison Qualtrough, Riina Rautemaa‐Richardson International Endodontic Journal.2021; 54(12): 2243. CrossRef - In Vitro Evaluation of a New Combination of Three Antibiotic Paste Against Common Endodontic Pathogens
Prasanna Dahake, Nilima Thosar Journal of Islamic Dental Association of IRAN.2021; 33(3): 58. CrossRef - Effect of using diode laser on Enterococcus faecalis and its lipoteichoic acid (LTA) in chronic apical periodontitis
Zhaohui Zou, Junu Bhandari, Baiyan Xiao, Xiaoyue Liang, Yu Zhang, Guohui Yan Lasers in Medical Science.2021; 36(5): 1059. CrossRef - Prevalence of Bacteria of Genus Actinomyces in Persistent Extraradicular Lesions—Systematic Review
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Jennifer Galván-Pacheco, Marlen Vitales-Noyola, Ana M. González-Amaro, Heriberto Bujanda-Wong, Antonio Aragón-Piña, Verónica Méndez-González, Amaury Pozos-Guillén Journal of Oral Science.2020; 62(4): 415. CrossRef - Comparison of the use of d-enantiomeric and l-enantiomeric antimicrobial peptides incorporated in a calcium-chelating irrigant against Enterococcus faecalis root canal wall biofilms
Wei-hu Ye, Lara Yeghiasarian, Christopher W. Cutler, Brian E. Bergeron, Stephanie Sidow, Hockin H.K. Xu, Li-na Niu, Jing-zhi Ma, Franklin R. Tay Journal of Dentistry.2019; 91: 103231. CrossRef
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Antifungal effects of synthetic human β-defensin 3-C15 peptide
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Sang-Min Lim, Ki-Bum Ahn, Christine Kim, Jong-Won Kum, Hiran Perinpanayagam, Yu Gu, Yeon-Jee Yoo, Seok Woo Chang, Seung Hyun Han, Won-Jun Shon, Woocheol Lee, Seung-Ho Baek, Qiang Zhu, Kee-Yeon Kum
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Restor Dent Endod 2016;41(2):91-97. Published online March 17, 2016
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DOI: https://doi.org/10.5395/rde.2016.41.2.91
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Abstract
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The purpose of this ex vivo study was to compare the antifungal activity of a synthetic peptide consisting of 15 amino acids at the C-terminus of human β-defensin 3 (HBD3-C15) with calcium hydroxide (CH) and Nystatin (Nys) against Candida albicans (C. albicans) biofilm. Materials and MethodsC. albicans were grown on cover glass bottom dishes or human dentin disks for 48 hr, and then treated with HBD3-C15 (0, 12.5, 25, 50, 100, 150, 200, and 300 µg/mL), CH (100 µg/mL), and Nys (20 µg/mL) for 7 days at 37℃. On cover glass, live and dead cells in the biomass were measured by the FilmTracer Biofilm viability assay, and observed by confocal laser scanning microscopy (CLSM). On dentin, normal, diminished and ruptured cells were observed by field-emission scanning electron microscopy (FE-SEM). The results were subjected to a two-tailed t-test, a one way analysis variance and a post hoc test at a significance level of p = 0.05. ResultsC. albicans survival on dentin was inhibited by HBD3-C15 in a dose-dependent manner. There were fewer aggregations of C. albicans in the groups of Nys and HBD3-C15 (≥ 100 µg/mL). CLSM showed C. albicans survival was reduced by HBD3-C15 in a dose dependent manner. Nys and HBD3-C15 (≥ 100 µg/mL) showed significant fungicidal activity compared to CH group (p < 0.05). ConclusionsSynthetic HBD3-C15 peptide (≥ 100 µg/mL) and Nys exhibited significantly higher antifungal activity than CH against C. albicans by inhibiting cell survival and biofilm.
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Yeon-Jee Yoo, Ikyung Kwon, So-Ram Oh, Hiran Perinpanayagam, Sang-Min Lim, Ki-Bum Ahn, Yoon Lee, Seung-Hyun Han, Seok-Woo Chang, Seung-Ho Baek, Qiang Zhu, Kee-Yeon Kum Journal of Endodontics.2017; 43(11): 1857. CrossRef - A 15-amino acid C-terminal peptide of beta-defensin-3 inhibits bone resorption by inhibiting the osteoclast differentiation and disrupting podosome belt formation
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Effect of acidic solutions on the microhardness of dentin and set OrthoMTA and their cytotoxicity on murine macrophage
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Soram Oh, Hiran Perinpanayagam, Yoon Lee, Jae-Won Kum, Yeon-Jee Yoo, Sang-Min Lim, Seok Woo Chang, Won-Jun Shon, Woocheol Lee, Seung-Ho Baek, Kee-Yeon Kum
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Restor Dent Endod 2016;41(1):12-21. Published online December 1, 2015
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DOI: https://doi.org/10.5395/rde.2016.41.1.12
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Abstract
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- Objectives
To evaluate the effects of three acids on the microhardness of set mineral trioxide aggregate (MTA) and root dentin, and cytotoxicity on murine macrophage. Materials and MethodsOrthoMTA (BioMTA) was mixed and packed into the human root dentin blocks of 1.5 mm diameter and 5 mm height. Four groups, each of ten roots, were exposed to 10% citric acid (CA), 5% glycolic acid (GA), 17% ethylenediaminetetraacetic acid (EDTA), and saline for five minutes after setting of the OrthoMTA. Vickers surface microhardness of set MTA and dentin was measured before and after exposure to solutions, and compared between groups using one-way ANOVA with Tukey test. The microhardness value of each group was analyzed using student t test. Acid-treated OrthoMTA and dentin was examined by scanning electron microscope (SEM). Cell viability of tested solutions was assessed using WST-8 assay and murine macrophage. ResultsThree test solutions reduced microhardness of dentin. 17% EDTA demonstrated severe dentinal erosion, significantly reduced the dentinal microhardness compared to 10% CA (p = 0.034) or 5% GA (p = 0.006). 10% CA or 5% GA significantly reduced the surface microhardness of set MTA compared to 17% EDTA and saline (p < 0.001). Acid-treated OrthoMTA demonstrated microporous structure with destruction of globular crystal. EDTA exhibited significantly more cellular toxicity than the other acidic solutions at diluted concentrations (0.2, 0.5, 1.0%). ConclusionsTested acidic solutions reduced microhardness of root dentin. Five minute's application of 10% CA and 5% GA significantly reduced the microhardness of set OrthoMTA with lower cellular cytotoxicity compared to 17% EDTA.
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- Impact of calcium hydroxide and 2-hydroxyisocaproic acid on the microhardness of root dentine: an in vitro study
Nandini T. Niranjan, Protim Ghosh Dastidar, Raghavendra Penukonda, Galvin Sim Siang Lin, Roopa Babannavar, Arun Jaysheel, Harshada Pattar Odontology.2024; 112(3): 711. CrossRef - Evaluation of the Effect of Chitosan-Based Irrigation Solutions on the Bond Strength of Mineral Trioxide Aggregate to Bulk-Fill Composite
Arzu Şahin Mantı, Bağdagül Helvacıoğlu Kıvanç Journal of Functional Biomaterials.2024; 15(12): 370. CrossRef - Effect of Various Acid Solutions as an Aid in Removing the OrthoMTA-Based Root Canal Filling
Naveen Chhabra, Abhishek Parolia Materials.2023; 16(13): 4535. CrossRef - Effect of Glycolic Acid, Maleic Acid, and EDTA in the Removal of Smear Layer from Root Canal Dentin
Tarini Mullick, Nidambur Vasudev Ballal Pesquisa Brasileira em Odontopediatria e Clínica Integrada.2023;[Epub] CrossRef - A comparative evaluation of the effect of various chelating agents on the microhardness of root canal dentin: An in vitro study
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Carolyn Primus, James L. Gutmann, Franklin R. Tay, Anna B. Fuks Journal of the American Ceramic Society.2022; 105(3): 1841. CrossRef - Influence of Acidic Environmental Conditions on Push-Out Bonding Strength of Four Calcium Silicate-Based Materials to Root Dentin
Beliz Özel, Raif Erişen, Boonlert Kukiattrakoon International Journal of Dentistry.2022; 2022: 1. CrossRef - The effects of sodium hypochlorite and ethylenediaminetetraacetic acid on the microhardness of Mineral Trioxide Aggregate and TotalFill Bioceramic Putty
Jacklyn H.R. Chu, Kalie Y. Chia, Alexander L. Qui, Alex Moule, William N. Ha Australian Endodontic Journal.2020; 46(1): 33. CrossRef - Pre-application of dentin bonding agent prevents discoloration caused by mineral trioxide aggregate
Yoo-Lim Choi, Young-Eun Jang, Bom Sahn Kim, Jin-Woo Kim, Yemi Kim BMC Oral Health.2020;[Epub] CrossRef - Glycolic acid as the final irrigant in endodontics: Mechanical and cytotoxic effects
Yuri Dal Bello, Hisadora Fracaro Porsch, Ana Paula Farina, Matheus Albino Souza, Emmanuel João Nogueira Leal Silva, Ana Karina Bedran-Russo, Doglas Cecchin Materials Science and Engineering: C.2019; 100: 323. CrossRef - Carbohydrate-electrolyte drinks exhibit risks for human enamel surface loss
Mary Anne Sampaio de Melo, Vanara Florêncio Passos, Juliana Paiva Marques Lima, Sérgio Lima Santiago, Lidiany Karla Azevedo Rodrigues Restorative Dentistry & Endodontics.2016; 41(4): 246. CrossRef
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Marginal and internal fit of nano-composite CAD/CAM restorations
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So-Hyun Park, Yeon-Jee Yoo, Yoo-Jin Shin, Byeong-Hoon Cho, Seung-Ho Baek
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Restor Dent Endod 2016;41(1):37-43. Published online January 19, 2016
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DOI: https://doi.org/10.5395/rde.2016.41.1.37
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Abstract
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- Objectives
The purpose of this study was to compare the marginal and internal fit of nano-composite CAD-CAM restorations. Materials and MethodsA full veneer crown and an mesio-occluso-distal (MOD) inlay cavity, which were prepared on extracted human molars, were used as templates of epoxy resin replicas. The prepared teeth were scanned and CAD-CAM restorations were milled using Lava Ultimate (LU) and experimental nano-composite CAD/CAM blocks (EB) under the same milling parameters. To assess the marginal and internal fit, the restorations were cemented to replicas and were embedded in an acrylic mold for sectioning at 0.5 mm intervals. The measured gap data were pooled according to the block types and measuring points for statistical analysis. ResultsBoth the block type and measuring point significantly affected gap values, and their interaction was significant (p = 0.000). In crowns and inlays made from the two blocks, gap values were significantly larger in the occlusal area than in the axial area, while gap values in the marginal area were smallest (p < 0.001). Among the blocks, the restorations milled from EB had a significantly larger gap at all measuring points than those milled from LU (p = 0.000). ConclusionsThe marginal and internal gaps of the two nano-composite CAD/CAM blocks differed according to the measuring points. Among the internal area of the two nano-composite CAD/CAM restorations, occlusal gap data were significantly larger than axial gap data. The EB crowns and inlays had significantly larger gaps than LU restorations.
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Yoen Ah Lim, Jeong Mi Kim, Yoorina Choi, Sujung Park European Journal of Dentistry.2023; 17(04): 1029. CrossRef - Microscopic Inspection of the Adhesive Interface of Composite Onlays after Cementation on Low Loading: An In Vitro Study
Tiago Magalhães, Rita Fidalgo-Pereira, Orlanda Torres, Óscar Carvalho, Filipe S. Silva, Bruno Henriques, Mutlu Özcan, Júlio C. M. Souza Journal of Functional Biomaterials.2023; 14(3): 148. CrossRef - Triple scan evaluation of internal and marginal adaptation of overlays using different restorative materials
Cynthia Kassis, Carina Mehanna, Pierre Khoury, Hani Tohme, Carlos Enrique Cuevas‐Suárez, Rim Bourgi, Monika Lukomska‐Szymanska, Louis Hardan Journal of Esthetic and Restorative Dentistry.2023; 35(3): 493. CrossRef - Effect of Bonding Protocols on the Performance of Luting Agents Applied to CAD–CAM Composites
Bruna Hilgemberg, Fabiana Suelen Figuerêdo de Siqueira, Andres Felipe Millan Cardenas, Josiane Loch Ribeiro, Andrés Dávila-Sánchez, Salvatore Sauro, Alessandro Dourado Loguercio, Cesar Augusto Galvao Arrais Materials.2022; 15(17): 6004. CrossRef - Marginal and internal fit and fracture resistance of three‐unit provisional restorations fabricated by additive, subtractive, and conventional methods
Mehran Falahchai, Samiye Rahimabadi, Ghazaleh Khabazkar, Yasamin Babaee Hemmati, Hamid Neshandar Asli Clinical and Experimental Dental Research.2022; 8(6): 1404. CrossRef - Analysis of Cosmetic Effect of Nanocomposite Resin on Anterior Teeth
Yubo Wang, Junfu Li, Daiyun Chen, Li Li, Tao Huang Computational and Mathematical Methods in Medicine.2021; 2021: 1. CrossRef - Microleakage and Marginal Integrity of Direct and Indirect Composite Resin Restorations in MOD Cavities After Thermo-Mechanical Loading
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Kun Qian, Xin Yang, Hailan Feng, Yihong Liu Advances in Applied Ceramics.2020; 119(5-6): 284. CrossRef - BİLGİSAYAR DESTEKLİ TASARIM-BİLGİSAYAR DESTEKLİ ÜRETİM SİSTEMLERİNİN FARKLI DENTAL RESTORASYONLARIN KENAR VE İÇ YÜZEY UYUMLARINA ETKİSİNİN DEĞERLENDİRİLMESİ: İN-VİTRO ÇALIŞMA
Merve BENLİ, Bilge GÖKÇEN-ROHLİG Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2020;[Epub] CrossRef - BİLGİSAYAR DESTEKLİ TASARIM-BİLGİSAYAR DESTEKLİ ÜRETİM SİSTEMLERİNİN FARKLI DENTAL RESTORASYONLARIN KENAR VE İÇ YÜZEY UYUMLARINA ETKİSİNİN DEĞERLENDİRİLMESİ: İN-VİTRO ÇALIŞMA
Merve BENLİ, Bilge GÖKÇEN-ROHLİG Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2020; : 1. CrossRef - Marginal and internal fit of CAD-CAM inlay/onlay restorations: A systematic review of in vitro studies
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Yuki NARUSE, Tomohiro TAKAGAKI, Naoko MATSUI, Takaaki SATO, Alghamdi ALI, Masaomi IKEDA, Toru NIKAIDO, Junji TAGAMI Dental Materials Journal.2018; 37(5): 805. CrossRef - Comparison between direct chairside and digitally fabricated temporary crowns
Adil O. ABDULLAH, Sarah POLLINGTON, Yi LIU Dental Materials Journal.2018; 37(6): 957. CrossRef - Edge strength of CAD/CAM materials
Maria Pfeilschifter, Verena Preis, Michael Behr, Martin Rosentritt Journal of Dentistry.2018; 74: 95. CrossRef - Influence of preparation, fitting, and cementation on the vitro performance and fracture resistance of CAD/CAM crowns
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Cutting efficiency of apical preparation using ultrasonic tips with microprojections: confocal laser scanning microscopy study
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Sang-Won Kwak, Young-Mi Moon, Yeon-Jee Yoo, Seung-Ho Baek, WooCheol Lee, Hyeon-Cheol Kim
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Restor Dent Endod 2014;39(4):276-281. Published online July 22, 2014
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DOI: https://doi.org/10.5395/rde.2014.39.4.276
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Abstract
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- Objectives
The purpose of this study was to compare the cutting efficiency of a newly developed microprojection tip and a diamond-coated tip under two different engine powers. Materials and MethodsThe apical 3-mm of each root was resected, and root-end preparation was performed with upward and downward pressure using one of the ultrasonic tips, KIS-1D (Obtura Spartan) or JT-5B (B&L Biotech Ltd.). The ultrasonic engine was set to power-1 or -4. Forty teeth were randomly divided into four groups: K1 (KIS-1D / Power-1), J1 (JT-5B / Power-1), K4 (KIS-1D / Power-4), and J4 (JT-5B / Power-4). The total time required for root-end preparation was recorded. All teeth were resected and the apical parts were evaluated for the number and length of cracks using a confocal scanning micrscope. The size of the root-end cavity and the width of the remaining dentin were recorded. The data were statistically analyzed using two-way analysis of variance and a Mann-Whitney test. ResultsThere was no significant difference in the time required between the instrument groups, but the power-4 groups showed reduced preparation time for both instrument groups (p < 0.05). The K4 and J4 groups with a power-4 showed a significantly higher crack formation and a longer crack irrespective of the instruments. There was no significant difference in the remaining dentin thickness or any of the parameters after preparation. ConclusionsUltrasonic tips with microprojections would be an option to substitute for the conventional ultrasonic tips with a diamond coating with the same clinical efficiency.
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Citations
Citations to this article as recorded by 
- Effectiveness of Sectioning Method and Filling Materials on Roughness and Cell Attachments in Root Resection Procedure
Tarek Ashi, Naji Kharouf, Olivier Etienne, Bérangère Cournault, Pierre Klienkoff, Varvara Gribova, Youssef Haikel European Journal of Dentistry.2025; 19(01): 240. CrossRef - Questioning the spot light on Hi-tech endodontics
Jojo Kottoor, Denzil Albuquerque Restorative Dentistry & Endodontics.2016; 41(1): 80. CrossRef
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Multivariate analysis of the cleaning efficacy of different final irrigation techniques in the canal and isthmus of mandibular posterior teeth
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Yeon-Jee Yoo, WooCheol Lee, Hyeon-Cheol Kim, Won-Jun Shon, Seung-Ho Baek
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Restor Dent Endod 2013;38(3):154-159. Published online August 23, 2013
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DOI: https://doi.org/10.5395/rde.2013.38.3.154
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Abstract
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- Objectives
The aim of this study was to compare the cleaning efficacy of different final irrigation regimens in canal and isthmus of mandibular molars, and to evaluate the influence of related variables on cleaning efficacy of the irrigation systems. Materials and MethodsMesial root canals from 60 mandibular molars were prepared and divided into 4 experimental groups according to the final irrigation technique: Group C, syringe irrigation; Group U, ultrasonics activation; Group SC, VPro StreamClean irrigation; Group EV, EndoVac irrigation. Cross-sections at 1, 3 and 5 mm levels from the apex were examined to calculate remaining debris area in the canal and isthmus spaces. Statistical analysis was completed by using Kruskal-Wallis test and Mann-Whitney U test for comparison among groups, and multivariate linear analysis to identify the significant variables (regular replenishment of irrigant, vapor lock management, and ultrasonic activation of irrigant) affecting the cleaning efficacy of the experimental groups. ResultsGroup SC and EV showed significantly higher canal cleanliness values than group C and U at 1 mm level (p < 0.05), and higher isthmus cleanliness values than group U at 3 mm and all levels of group C (p < 0.05). Multivariate linear regression analysis demonstrated that all variables had independent positive correlation at 1 mm level of canal and at all levels of isthmus with statistical significances. ConclusionsBoth VPro StreamClean and EndoVac system showed favorable result as final irrigation regimens for cleaning debris in the complicated root canal system having curved canal and/or isthmus. The debridement of the isthmi significantly depends on the variables rather than the canals.
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Citations
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- Efficacy of different irrigant activation techniques for cleaning root canal anastomosis
O. K. Montaser, D. M. Fayyad, N. Abdelsalam BMC Oral Health.2023;[Epub] CrossRef - Activación ultrasónica durante la preparación bio químico mecánica del tratamiento endodóntico no quirúrgico. Revisión de la literatura
Gisselle Cantanzaro, Nelsin Villaroel, Diana Dorta ODOUS Científica .2022; 22(2): 135. CrossRef - Heated distilled water with or without continuous ultrasonic irrigation improves final irrigation efficacy and reduces dentine erosion
Michelli Cássia dos Santos, Cleonice da Silveira Teixeira, Lucas da Fonseca Roberti Garcia, Bruno Henriques, Franklin R. Tay, Eduardo Antunes Bortoluzzi Journal of Dentistry.2020; 103: 103507. CrossRef - Ultrasonic Irrigant Activation during Root Canal Treatment: A Systematic Review
Petruţa E. Căpută, Anastasios Retsas, Lydwien Kuijk, Luis E. Chávez de Paz, Christos Boutsioukis Journal of Endodontics.2019; 45(1): 31. CrossRef - Irrigation effectiveness of continuous ultrasonic irrigation system: An ex vivo study
Ahmed JAMLEH, Hideaki SUDA, Carlos G. ADORNO Dental Materials Journal.2018; 37(1): 1. CrossRef - Apical negative pressure irrigation versus syringe irrigation: a systematic review of cleaning and disinfection of the root canal system
E. Konstantinidi, Z. Psimma, L. E. Chávez de Paz, C. Boutsioukis International Endodontic Journal.2017; 50(11): 1034. CrossRef - Effect of Different Agitation Techniques on the Penetration of Irrigant and Sealer into Dentinal Tubules
Yu Gu, Hiran Perinpanayagam, David J.W. Jin, Yeon-Jee Yoo, Jin-Sun Jeong, Sang-Min Lim, Seok-Woo Chang, Seung-Ho Baek, Qiang Zhu, Kee-Yeon Kum Photomedicine and Laser Surgery.2017; 35(2): 71. CrossRef - Effectiveness of Sonic, Ultrasonic, and Photon-Induced Photoacoustic Streaming Activation of NaOCl on Filling Material Removal Following Retreatment in Oval Canal Anatomy
Shan Jiang, Ting Zou, Dongxia Li, Jeffery W.W. Chang, Xiaojing Huang, Chengfei Zhang Photomedicine and Laser Surgery.2016; 34(1): 3. CrossRef - Efficacy of Needle, Ultrasonic, and Endoactivator Irrigation and Photon-Induced Photoacoustic Streaming in Removing Calcium Hydroxide from the Main Canal and Isthmus: AnIn VitroMicro-Computed Tomography and Scanning Electron Microscopy Study
Dongxia Li, Shan Jiang, Xingzhe Yin, Jeffrey Wen Wei Chang, Jie Ke, Chengfei Zhang Photomedicine and Laser Surgery.2015; 33(6): 330. CrossRef - Effect of three different irrigation solutions applied by passive ultrasonic irrigation
Carmen Llena, Leopoldo Forner, Raquel Cambralla, Adrian Lozano Restorative Dentistry & Endodontics.2015; 40(2): 143. CrossRef
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Clinical assessment of whitening efficacy and safety of in-office tooth whitening system containing 15% hydrogen peroxide with or without light activation
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Young-Suk Noh, Young-Jee Rho, Yeon-Jee Yoo, Hyang-Ok Lee, Sang-Min Lim, Hyun-Jeong Kweon, Yeun Kim, Seong-Yeon Park, Hee-Young Yoon, Jung-Hyun Lee, Chan-Hee Lee, So-Ram Oh, Kee-Yeon Kum
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J Korean Acad Conserv Dent 2011;36(4):306-312. Published online July 31, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.4.306
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Abstract
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Objectives
This clinical study evaluated the effect of light activation on the whitening efficacy and safety of in-office bleaching system containing 15% hydrogen peroxide gel.
Materials and Methods
Thirty-three volunteers were randomly treated with (n = 17, experimental group) or without light activation (n = 16, control group), using Zoom2 white gel (15% H2O2, Discus Dental) for a total treatment time of 45 min. Visual and instrumental color measurements were obtained using Vitapan Classical shade guide and Shadepilot (DeguDent) at screening test, after bleaching, and 1 month and 3 month after bleaching. Data were analyzed using t-test, repeated measure ANOVA, and chi-squared test.
Results
Zoom2 white gel produced significant shade changes in both experimental and control group when pre-treatment shade was compared with that after bleaching. However, shade difference between two groups was not statistically significant (p > 0.05). Tooth shade relapse was not detected at 3 months after bleaching. The incidence of transient tooth sensitivity was 39.4%, with being no differences between two groups.
Conclusions
The application of light activation with Zoom2 white gel system neither achieved additional whitening effects nor showed more detrimental influences.
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Citations
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- Effect of preference drinks on tooth color reduction after tooth bleaching: A 12-momth follow-up study
Hyo Jin Goo, Min Jeong Cho, Yun Sook Jung, Ji Hye Kim, Fan Dong, Keun Bae Song Journal of Korean Academy of Oral Health.2016; 40(1): 55. CrossRef - Development of a Piezoelectric Ultrasonic Tooth-whitening Apparatus
Young-Jin Lee, Jong-Hoo Paik, Jeong-Bae Lee, Seung-Jae Choi Transactions on Electrical and Electronic Materials.2013; 14(5): 268. CrossRef
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Review of root canal irrigant delivery techniques and devices
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Yeon-Jee Yoo, Su-Jeong Shin, Seung-Ho Baek
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J Korean Acad Conserv Dent 2011;36(3):180-187. Published online May 31, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.3.180
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Abstract
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Introduction
Eliminating the residual debris and bacteria in the root canal system is one of the main purposes of the endodontic treatment. However, the complexity on the anatomy of the root canal system makes it difficult to eliminate the bacterial biofilm existing along the root canal surface and necrotic pulp tissue by mechanical instrumentation and chemical irrigation. Recently, more effective irrigant delivery systems for root canal irrigation have been developed. The purpose of this review was to present an overview of root canal irrigant delivery techniques and devices available in endodontics.
Review
The contents of this paper include as follows;
- syringe-needle irrigation, manual dynamic irrigation, brushes
- sonic and ultrasonic irrigation, passive ultrasonic irrigation, rotary brush, RinsEndo, EndoVac, Laser
Conclusion
Though technological advances during the last decade have brought to fruition new agitation devices that rely on various mechanisms, there are few evidence based study to correlate the clinical efficacy of these devices with improved outcomes except syringe irrigation with needle and ultrasonic irrigation.
The clinicians should try their best efforts to deliver antimicrobial and tissue solvent solutions in predictable volumes safely to working length.
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Citations
Citations to this article as recorded by 
- Development and performance test of a micro bubble irrigation system for root canal cleaning of tooth
Gilhwan Sung, Jaeyong Sung, Myeong Ho Lee Journal of the Korean Society of Visualization.2016; 14(1): 40. CrossRef
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Evaluation of apical canal shapes produced sequentially during instrumentation with stainless steel hand and Ni-Ti rotary instruments using Micro-computed tomography
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Woo-Jin Lee, Jeong-Ho Lee, Kyung-A Chun, Min-Seock Seo, Yeon-Jee Yoo, Seung-Ho Baek
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J Korean Acad Conserv Dent 2011;36(3):231-237. Published online May 31, 2011
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DOI: https://doi.org/10.5395/JKACD.2011.36.3.231
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Abstract
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Objectives
The purpose of this study was to determine the optimal master apical file size with minimal transportation and optimal efficiency in removing infected dentin. We evaluated the transportation of the canal center and the change in untouched areas after sequential preparation with a #25 to #40 file using 3 different instruments: stainless steel K-type (SS K-file) hand file, ProFile and LightSpeed using microcomputed tomography (MCT).
Materials and Methods
Thirty extracted human mandibular molars with separated orifices and apical foramens on mesial canals were used. Teeth were randomly divided into three groups: SS K-file, Profile, LightSpeed and the root canals were instrumented using corresponding instruments from #20 to #40. All teeth were scanned with MCT before and after instrumentation. Cross section images were used to evaluate canal transportation and untouched area at 1- , 2- , 3- , and 5- mm level from the apex. Data were statistically analyzed according to' repeated nested design'and Mann-Whitney test (p = 0.05).
Results
In SS K-file group, canal transportation was significantly increased over #30 instrument. In the ProFile group, canal transportation was significantly increased after preparation with the #40 instrument at the 1- and 2- mm levels. LightSpeed group showed better centering ability than ProFile group after preparation with the #40 instrument at the 1 and 2 mm levels.
Conclusions
SS K-file, Profile, and LightSpeed showed differences in the degree of apical transportation depending on the size of the master apical file.
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Citations
Citations to this article as recorded by 
- Comparison of the shaping abilities of three nickel–titanium instrumentation systems using micro-computed tomography
Jin Yi Baek, Hyun Mi Yoo, Dong Sung Park, Tae Seok Oh, Kee Yeon Kum, Seung Yun Shin, Seok Woo Chang Journal of Dental Sciences.2014; 9(2): 111. CrossRef
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