Pulp tissue regeneration and root formation of permanent teeth with pulpal/periapical deseases

Yeon-Jee Yoo; Seung-Ho Baek; Ho-Hyun Son

doi:10.5395/JKACD.2010.35.4.238

Articles

Page Path: HOME > Restor Dent Endod > Volume 35(4); 2010 > Article

Review Article Pulp tissue regeneration and root formation of permanent teeth with pulpal/periapical deseases: Yeon-Jee Yoo, Seung-Ho Baek, Ho-Hyun Son; Journal of Korean Academy of Conservative Dentistry 2010;35(4):238-245.
DOI: https://doi.org/10.5395/JKACD.2010.35.4.238
Published online: July 31, 2010

Department of Conservative Dentistry, School of Dentistry, Seoul National University, Seoul, Korea.

Corresponding Author: Ho-Hyun Son. Department of Conservative Dentistry and Dental Research, Institute, School of Dentistry, Seoul National University, 28-2 Yeongeon-Dong, Jongro-Gu, Seoul, 110-749, Korea. Tel: +82-2-2072-2652 Fax: +82-2-2072-3859, hhson@snu.ac.kr

• Received: June 23, 2010 • Revised: June 28, 2010 • Accepted: June 30, 2010

21 Views
0 Download

prev next

Full Article

Download PDF

Abstract
REFERENCES

Abstract

Numerous cases about additional growth of roots or pulp tissue regeneration by using various intracanal medicaments in immature permanent teeth with periapical or pulpal disease have been reported. The underlying mechanism has not been clearly delineated, but it has been widely accepted that undifferentiated mesenchymal cells and stem cells are involved. Moreover, the growth and deposition of osteoid or cementoid tissues have been observed in regenerated pulp and roots. This new and non-invasive treatment has brightened the future of endodontics, and enlarged the vision of regenerative root canal treatment with multi-potent stem cells and various tissue engineering techniques.
Keywords: Revascularization; Pulp tissue regeneration; Root formation; Tri-antibiotic paste; Tissue engineering

REFERENCES

1. Rafter M. Apexification: a review. Dental Traumatology. 2005;21: 1-8.PubMed
2. Bishop BG, Woollard GW. Modern endodontic therapy for an incompletely developed tooth. General Dentistry. 2002;50: 252-256.PubMed
3. Goldstein S, Sedaghat-Zandi A, Greenberg M, Friedman S. Apexification & apexogenesis. The New York State Dental Journal. 1999;65: 23-25.PubMed
4. Webber RT. Apexogenesis versus apexification. Dent Clin North Am. 1984;28: 669-697.PubMed
5. Iwaya SI, Ikawa M, Kubota M. Revascularization of an immature permanent tooth with apical periodontitis and sinus tract or/not. Dental Traumatology. 2001;17: 185-187.PubMed
6. Rafter M. Vital pulp therapy-a review. Journal of the Irish Dental Association. 2001;47: 115-121.PubMed
7. Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells. J Dent Res. 2002;81: 531-535.Article PubMed PDF
8. Chueh L-H, Huang GTJ. Immature teeth with periradicular periodontitis or abscess undergoing apexogenesis: a paradigm shift. J Endod. 2006;32: 1205-1213.PubMed
9. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod. 2004;30: 196-200.PubMed
10. Thibodeau B, Trope M. Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature. Pediatric Dentistry. 2007;29: 47-50.PubMed
11. Lieberman J, Trowbridge H. Apical closure of non vital permanent incisor teeth where no treatment was performed: case report. J Endod. 1983;9: 257-260.Article PubMed
12. Nevins A, Wrobel W, Valachovic R, Finkelstein F. Hard tissue induction into pulpless open-apex teeth using collagen-calcium phosphate gel. J Endod. 1977;3: 431-433.PubMed
13. Krebsbach P, Kuznetsov SA, Satomura K, Emmons RV, Rowe DW, Robey PG. Bone formation in vivo: comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts. Transplantation. 1997;63: 1059-1069.PubMed
14. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA. 2000;97: 13625-13630.PubMed PMC
15. Wang Q, Lin XJ, Lin ZY, Liu GX, Shan XL. Expression of vascular endothelial growth factor in dental pulp of immature and mature permanent teeth in human. Shanghai Kou Qiang Yi Xue. 2007;16: 285-289.PubMed
16. Nevins A, Finkelstein F, Laporta R, Borden BG. Induction of hard tissue into pulpless open apex teeth using collagen-calcium phosphate gel. J Endod. 1978;4: 76-81.PubMed
17. Nevins A, Wrobel W, Valachovic R, Finkelstein F. Hard tissue induction into pulpless open apex teeth using collagen-calcium phosphate gel. J Endod. 1977;3: 431-433.PubMed
18. Ellis E 3rd, Cox CF, Hitchcock R, Baker J. Vital apicoectomy of the teeth: a 1-4 week histopathological study in Macaca mulatta. J Oral Pathol. 1985;14: 718-732.PubMed
19. Hitchcock R, Ellis E 3rd, Cox CF. Intentional vital root transection: a 52-week histopathologic study in Macaca mulatta. Oral Surg Oral Med Oral Pathol. 1985;60: 2-14.Article PubMed
20. Wei X, Ling J, Wu L, Liu L, Xiao Y. Expression of mineralization markers in dental pulp cells. J Endod. 2007;33: 703-708.PubMed
21. Huang GT, Shagramanova K, Chan SW. Formation of odontoblast-like cells from cultured human dental pulp cells on dentin in vitro. J Endod. 2006;32: 1066-1073.PubMed
22. Ritter AL, Ritter AV, Murrah V, Sigurdsson A, Trope M. Pulp revascularization of replanted immature dog teeth after treatment with minocyline and doxycycline assessed by laser Doppler flowmetry, radiography, and histology. Dent Traumatol. 2004;20: 75-84.PubMed
23. Wang X, Thibodeau B, Trope M, Lin LM, Huang GTJ. Histologic Characterization of Regenerated Tissues in Canal Space after the Revitalization/Revascularization Procedure of Immature Dog Teeth with Apical Periodontitis. J Endod. 2010;36: 56-63.Article PubMed
24. Cooke C, Rowbotham TC. The closure of open apices in nonvital immature incisor teeth. British Dental Journal. 1988;165: 420-421.
25. Sonoyama W, Liu Y, Yamaza T, Tuan RS, Wang S, Shi S, et al. Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study. J Endod. 2008;34: 166-171.PubMed PMC
26. Kaiser HJ. Management of wide open apex canals with calcium hydroxide. Presented at the 21st Annual Meeting of the American Association of Endodontists. April 17 1964. Washington DC.
27. Klein SH, Levy BA. Histologic evaluation of induced apical closure of a human pulpless tooth. Oral Surg. 1974;38: 954-959.Article PubMed
28. Schroder U, Granath L. Early reaction of intact human teeth to calcium hydroxide following experimental pulpotomy and its significance to the development of hard tissue barrier. Odontol Revy. 1971;22: 379-395.PubMed
29. Pisanti S, Sciaky I. Origin of calcium in the repair wall after pulp exposure in the dog. J Dent Res. 1964;43: 641-644.PubMed
30. Ghose LJ, Bagdady VS, Hikmat BYM. Apexification of immature apices of pulpless permanent anterior teeth with calcium hydroxide. J Endod. 1987;13: 285-290.PubMed
31. Baldassari-Cruz LA, Walton RE, Johnson WT. Scanning electron microscopy and histologic analysis of an apexification 'cap'. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;86: 465-468.Article PubMed
32. Trope M. Treatmente of immature teeth with non-vital pulps and apical periodontitis. Endodontic Topics. 2006;14: 51-59.
33. Sim TP, Knowles JC, Ng YL, Shelton J, Gulabivala K. Effect of sodium hypochlorite on mechanical properties of dentine and tooth surface strain. Int Endod J. 2001;34: 120-132.Article PubMed PDF
34. Driscoll CO, Dowker SE, Anderson P, Wilson RM, Gulabivala K. Effects of sodium hypochlorite solution on root dentine composition. J Mater Sci Mater Med. 2002;13: 219-223.PubMed
35. Grigoratos D, Knowles J, Ng Y-L, Gulabivala K. Effect of exposing dentin to sodium hypochlorite and calcium hydroxide on its flexural strength and elastic modulus. Int Endod J. 2001;34: 113-119.PubMed
36. Sato I, Ando-Kurihara N, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of amixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J. 1996;29: 118-124.PubMed
37. Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K, et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J. 1996;29: 125-130.Article PubMed
38. Thibodeau B, Teixeira F, Yamauchi M, Caplan DJ, Trope M. Pulp revascularization of immature dog teeth with apical periodontitis. J Endod. 2007;33: 680-689.PubMed
39. Jung IY, Lee SJ, Hargreaves KM. Biologically based treatment of immature permanent teeth with pulpal necrosis; a case series. J Endod. 2008;34: 876-887.Article PubMed

Tables & Figures

REFERENCES

Citations

Citations to this article as recorded by

ePub Link

Cite

CITE: export Copy Download Format; Close

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Pulp tissue regeneration and root formation of permanent teeth with pulpal/periapical deseases

J Korean Acad Conserv Dent. 2010;35(4):238-245. Published online July 31, 2010

DOI: https://doi.org/10.5395/JKACD.2010.35.4.238

XML Download

Pulp tissue regeneration and root formation of permanent teeth with pulpal/periapical deseases