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A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide
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Basic Research A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide
Sin-Young Kim1, Je-Uk Park2, Chang-Hyen Kim2, Sung-Eun Yang1
Journal of Korean Academy of Conservative Dentistry 2010;35(3):198-210.
DOI: https://doi.org/10.5395/JKACD.2010.35.3.198
Published online: May 31, 2010

1Department of Conservative Dentistry, Seoul St. Mary's Hospital, Catholic University of Korea, Korea.

2Department of Oral and Maxillofacial Surgery, Seoul St. Mary's Hospital, Catholic University of Korea, Korea.

Correspondence to: Sung-Eun. Yang Department of Conservative Dentistry Seoul St. Mary's Hospital, Catholic University of Korea 505, Banpo-dong, Seocho-gu, Seoul, 137-044, Korea. Tel: 82-2-2258-6296, Fax: 82-2-537-2374, dentyeun@catholic.ac.kr
• Received: April 21, 2010   • Revised: April 26, 2010   • Accepted: April 29, 2010

Copyright © 2010 Korean Academy of Conservative Dentistry

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  • This study evaluated the safety of an office bleaching gel (RemeWhite, Remedent Inc., Deurle, Belgium) containing 30% hydrogen peroxide. 37 volunteers were recieved office bleaching with the RemeWhite for 3 times at one visit, total 2 visits. As control group, the same gel in which hydrogen peroxide was not included was applied to 34 volunteers with the same protocol.
    There was no difference between experimental group and control group using electric pulp test. In the result of gingival inflammation index and tooth sensitivity test, there was mild pain response in experimental group but it disappeared as time went by. Therefore, safety of the office bleaching gel containing 30% hydrogen peroxide was confirmed.
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Table 1
Experimental protocol of randomized clinical trial
jkacd-35-198-i001.jpg
Table 2
Age and gender of the participants in the study
jkacd-35-198-i002.jpg
Table 3
Changes of EPT (Electric pulp test)

1) Two sample t-test

2) Wilcoxon's rank sum test

*p < 0.05

jkacd-35-198-i003.jpg
Table 4
Changes of GI (gingival inflammation index)

1) McNemar's test

2) N/A: Not Applicable

*: p < 0.05

jkacd-35-198-i004.jpg
Table 5
Tooth sensitivity at each visit

1) McNemar's test

*: p < 0.05

jkacd-35-198-i005.jpg
Table 6
Percentage of abnormal response

1) Chi-square test

jkacd-35-198-i006.jpg
Table 7
Changes of vital sign

1) two sample t-test

2) Wilcoxon's rank sum test

*: p < 0.05

jkacd-35-198-i007.jpg

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        A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide
        J Korean Acad Conserv Dent. 2010;35(3):198-210.   Published online May 31, 2010
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      Related articles
      A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide
      A clinical evaluation of safety of an office bleaching gel containing 30% hydrogen peroxide

      Experimental protocol of randomized clinical trial

      Age and gender of the participants in the study

      Changes of EPT (Electric pulp test)

      1) Two sample t-test

      2) Wilcoxon's rank sum test

      *p < 0.05

      Changes of GI (gingival inflammation index)

      1) McNemar's test

      2) N/A: Not Applicable

      *: p < 0.05

      Tooth sensitivity at each visit

      1) McNemar's test

      *: p < 0.05

      Percentage of abnormal response

      1) Chi-square test

      Changes of vital sign

      1) two sample t-test

      2) Wilcoxon's rank sum test

      *: p < 0.05

      Table 1 Experimental protocol of randomized clinical trial

      Table 2 Age and gender of the participants in the study

      Table 3 Changes of EPT (Electric pulp test)

      1) Two sample t-test

      2) Wilcoxon's rank sum test

      *p < 0.05

      Table 4 Changes of GI (gingival inflammation index)

      1) McNemar's test

      2) N/A: Not Applicable

      *: p < 0.05

      Table 5 Tooth sensitivity at each visit

      1) McNemar's test

      *: p < 0.05

      Table 6 Percentage of abnormal response

      1) Chi-square test

      Table 7 Changes of vital sign

      1) two sample t-test

      2) Wilcoxon's rank sum test

      *: p < 0.05


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