Citations

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• A Morphometric Study of the Mandibular Foramen, Lingula, and the Incidence of Accessory Mandibular Foramina in Dry Mandibles
  Yashaswi Singh, Pratibha Shakya, Noor Us Saba, Heena Singh, Navneet Kumar
  Cureus.2025;[Epub]     CrossRef
• Effect of topical application of amitriptyline and nortriptyline on irreversible pulpitis pain in teeth with failed pulpal anesthesia after a successful inferior alveolar nerve block: A randomized clinical trial
  Armita Vali Sichani, Hossein Baharian, Navid Yaraghi, Zahra Khosravani, Asana Vali Sichani
  Dental Research Journal.2024;[Epub]     CrossRef
• The Effect of the Anatomic Variables on the Success Rate of Anesthesia in Maxillary Molars with Irreversible Pulpitis
  Masoud Parirokh, Sina Kakooei, Nouzar Nakhaee, Hamed Manochehrifar, Paul Abbott
  Journal of Endodontics.2022; 48(6): 707.     CrossRef
• Present status and future directions—Mechanisms and management of local anaesthetic failures
  Masoud Parirokh, Paul V. Abbott
  International Endodontic Journal.2022; 55(S4): 951.     CrossRef
• Local anesthesia in oral and maxillofacial surgery: A review of current opinion
  Yu-Hao Wang, Dian-Ri Wang, Ji-Yuan Liu, Jian Pan
  Journal of Dental Sciences.2021; 16(4): 1055.     CrossRef
• ANATOMICAL STUDY OF MANDIBULAR FORAMEN IN DRY ADULT HUMAN MANDIBLES IN BIHAR STATE REGION
  Vijay Kumar Singh, Md. Zahid Hussain, Subodh Kumar
  GLOBAL JOURNAL FOR RESEARCH ANALYSIS.2021; : 34.     CrossRef
• Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
  Saurav Paul, Sridevi Nandamuri, Aakrati Raina, Mukta Bansal
  Restorative Dentistry & Endodontics.2021;[Epub]     CrossRef
• Different anesthetics on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis
  Juliana Larocca de Geus, Jane Kenya Nogueira da Costa, Letícia Maíra Wambier, Bianca Medeiros Maran, Alessandro Dourado Loguercio, Alessandra Reis
  The Journal of the American Dental Association.2020; 151(2): 87.     CrossRef
• Efficacy of local anaesthetic solutions on the success of inferior alveolar nerve block in patients with irreversible pulpitis: a systematic review and network meta‐analysis of randomized clinical trials
  V. Nagendrababu, S. J. Pulikkotil, A. Suresh, S. K. Veettil, S. Bhatia, F. C. Setzer
  International Endodontic Journal.2019; 52(6): 779.     CrossRef
• The Effect of Sphenopalatine Block on the Postoperative Pain of Endoscopic Sinus Surgery: A Meta‐analysis
  Do Hyun Kim, Haram Kang, Se Hwan Hwang
  Otolaryngology–Head and Neck Surgery.2019; 160(2): 223.     CrossRef
• Effect of four local anesthetics (tetracaine, proparacaine, lidocaine, and bupivacaine) on intraocular pressure in dogs
  Ali Asghar Sarchahi, Mehdi Eskandari
  International Ophthalmology.2019; 39(7): 1467.     CrossRef
• Strategies for managing pain during endodontic treatment
  Paul V. Abbott, Masoud Parirokh
  Australian Endodontic Journal.2018; 44(2): 99.     CrossRef
• Is mepivacaine as effective as lidocaine during inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis? A systematic review and meta‐analysis
  W. A. Vieira, L. R. Paranhos, G. O. Cericato, A. Franco, M. A. G. Ribeiro
  International Endodontic Journal.2018; 51(10): 1104.     CrossRef
• Injectable local anaesthetic agents for dental anaesthesia
  Geoffrey St George, Alyn Morgan, John Meechan, David R Moles, Ian Needleman, Yuan-Ling Ng, Aviva Petrie
  Cochrane Database of Systematic Reviews.2018;[Epub]     CrossRef
• Successful pulpal anesthesia for symptomatic irreversible pulpitis
  Melissa Drum, Al Reader, John Nusstein, Sara Fowler
  The Journal of the American Dental Association.2017; 148(4): 267.     CrossRef
• The Effect of Photobiomodulation on the Depth of Anesthesia During Endodontic Treatment of Teeth With Symptomatic Irreversible Pulpitis (Double Blind Randomized Clinical Trial)
  Sholeh Ghabraei, Nasim Chiniforush, Behnam Bolhari, Mohsen Aminsobhani, Abbas Khosarvi
  Journal of Lasers in Medical Sciences.2017; 9(1): 11.     CrossRef
• Morphometric study on mandibular foramen and incidence of accessory mandibular foramen in mandibles of south Indian population and its clinical implications in inferior alveolar nerve block
  R. Shalini, C. RaviVarman, R. Manoranjitham, M. Veeramuthu
  Anatomy & Cell Biology.2016; 49(4): 241.     CrossRef
• The Effect of Maxillary First Molar Root Length on the Success Rate of Buccal Infiltration Anesthesia
  Ehsan Moradi Askari, Masoud Parirokh, Nouzar Nakhaee, Hamid Reza Hosseini, Paul V. Abbott
  Journal of Endodontics.2016; 42(10): 1462.     CrossRef
• Efficacy of Ketorolac Buccal Infiltrations and Inferior Alveolar Nerve Blocks in Patients with Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial
  Nahid Mohammadzadeh Akhlaghi, Behnoush Hormozi, Paul V. Abbott, Zohreh Khalilak
  Journal of Endodontics.2016; 42(5): 691.     CrossRef

Hypoesthesia after an inferior alveolar nerve (IAN) block does not commonly occur, but some cases are reported. The causes of hypoesthesia include a needle injury or toxicity of local anesthetic agents, and the incidence itself can cause stress to both dentists and patients. This case presents a hypoesthesia on mental nerve area followed by IAN block anesthesia with 2% lidocaine. Prescription of steroids for a week was performed and periodic follow up was done. After 1 wk, the symptoms got much better and after 4 mon, hypoesthesia completely disappeared. During this healing period, only early steroid medication was prescribed. In most cases, hypoesthesia is resolved within 6 mon, but being aware of etiology and the treatment options of hypoesthesia is important. Because the hypoesthesia caused by IAN block anesthesia is a mild to moderate nerve injury, early detection of symptom and prescription of steroids could be helpful for improvement of the hypoesthesia.

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• İMPLANT CERRAHİSİ SONRASI HİPOESTEZİ-6 AYLIK TAKİP: VAKA SERİSİ
  Sefa AYDINDOĞAN, Emine Elif MUTAFCİLAR VELİOĞLU, Yunus Emre BALABAN
  Selcuk Dental Journal.2023; 10(4): 350.     CrossRef
• Intranasal CRMP2-Ubc9 inhibitor regulates NaV1.7 to alleviate trigeminal neuropathic pain
  Santiago I. Loya-Lopez, Heather N. Allen, Paz Duran, Aida Calderon-Rivera, Kimberly Gomez, Upasana Kumar, Rory Shields, Rui Zeng, Akshat Dwivedi, Saumya Saurabh, Olga A. Korczeniewska, Rajesh Khanna
  Pain.2023;[Epub]     CrossRef
• Pathophysiology of Post-Traumatic Trigeminal Neuropathic Pain
  Olga A. Korczeniewska, Divya Kohli, Rafael Benoliel, Sita Mahalakshmi Baddireddy, Eli Eliav
  Biomolecules.2022; 12(12): 1753.     CrossRef
• Shape and anatomical relationship of the mental foramen to the mandibular premolars in an Indian sub-population: a retrospective CBCT analysis
  Komal Sheth, Kulvinder Singh Banga, Ajinkya M. Pawar, James L. Gutmann, Hyeon-Cheol Kim
  Restorative Dentistry & Endodontics.2022;[Epub]     CrossRef
• Trigeminal neuralgia and persistent idiopathic facial pain (atypical facial pain)
  Gary W. Jay, Robert L. Barkin
  Disease-a-Month.2022; 68(6): 101302.     CrossRef
• Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain
  Yan-Yan Zhang, Fei Liu, Zhong-Han Fang, Yue-Ling Li, Hong-Lin Liao, Qin-Xuan Song, Cheng Zhou, Jie-Fei Shen
  Brain, Behavior, and Immunity.2022; 106: 129.     CrossRef
• Visualization of Inferior Alveolar and Lingual Nerve Pathology by 3D Double-Echo Steady-State MRI: Two Case Reports with Literature Review
  Adib Al-Haj Husain, Daphne Schönegg, Silvio Valdec, Bernd Stadlinger, Thomas Gander, Harald Essig, Marco Piccirelli, Sebastian Winklhofer
  Journal of Imaging.2022; 8(3): 75.     CrossRef
• Molecular mechanisms of painful traumatic trigeminal neuropathy—Evidence from animal research and clinical correlates
  Olga A. Korczeniewska, Junad Khan, Eli Eliav, Rafael Benoliel
  Journal of Oral Pathology & Medicine.2020; 49(6): 580.     CrossRef
• Behavioral changes in calves 11 days after cautery disbudding: Effect of local anesthesia
  Sarah J.J. Adcock, Danielle M. Cruz, Cassandra B. Tucker
  Journal of Dairy Science.2020; 103(9): 8518.     CrossRef
• Frequency of Lower Lip Paresthesia in Patients Receiving Implant-Supported Mandibular Dentures in Tabriz, Iran in 2017-2018
  Farrokh Farhadi, Reza Khorshidi-Khiavi, Fereshteh Taheri, Milad Ghanizadeh
  Avicenna Journal of Dental Research.2019; 11(1): 26.     CrossRef
• Persistent idiopathic facial pain
  Rafael Benoliel, Charly Gaul
  Cephalalgia.2017; 37(7): 680.     CrossRef
• Painful Traumatic Trigeminal Neuropathy
  Rafael Benoliel, Sorin Teich, Eli Eliav
  Oral and Maxillofacial Surgery Clinics of North America.2016; 28(3): 371.     CrossRef
• Neuropathy of Trigeminal Nerve Branches After Oral and Maxillofacial Treatment
  Jimoh Olubanwo Agbaje, Elke Van de Casteele, Marjolein Hiel, Ciska Verbaanderd, Ivo Lambrichts, Constantinus Politis
  Journal of Maxillofacial and Oral Surgery.2016; 15(3): 321.     CrossRef
• The Enigma of the Mental Foramen as It Relates to Plastic Surgery
  Raphael Alves Chu, Fabio Xerfan Nahas, Marcello Di Martino, Fernanda Abibi Soares, Neil Ferreira Novo, Ricardo Luiz Smith, Lydia Masako Ferreira
  Journal of Craniofacial Surgery.2014; 25(1): 238.     CrossRef
• Mental nerve paresthesia secondary to initiation of endodontic therapy: a case report
  Syed Mukhtar-Un-Nisar Andrabi, Sharique Alam, Afaf Zia, Masood Hasan Khan, Ashok Kumar
  Restorative Dentistry & Endodontics.2014; 39(3): 215.     CrossRef
• Pain Sensation and Postsurgical Complications in Posterior Mandibular Implant Placement Using Ridge Mapping, Panoramic Radiography, and Infiltration Anesthesia
  Ali Saad Thafeed AlGhamdi
  ISRN Dentistry.2013; 2013: 1.     CrossRef

The aims of the study were to evaluate the effect of epinephrine-containing local anesthetics on pulpal blood flow (PBF) and to investigate its effect on cavity preparation-induced PBF change. PBF was recorded using a laser Doppler flowmeter (Perimed Co., Sweden) from canines of nine cats under general anesthesia before and after injection of local anesthetics and after cavity preparation. 2% lidocaine hydrochloride with 1 : 100,000 epinephrine was administered by local infiltration given apical to the mandibular canine at the vestibular area and the same volume of isotonic saline was injected on the contralateral tooth as a control. A round carbide bur was operated at slow speed with isotonic saline flushing to grind spherical cavities with increasing depth through the enamel and into the dentin on both teeth. The obtained data was analyzed with paired t-test.

Cavity preparation caused significant increase of PBF (n = 9, p < 0.05). Local infiltration of lidocaine with epinephrine resulted in decreases of PBF (n = 9, p < 0.05), whereas there was no significant change of PBF with the physiologic saline as a control. Cavity preparation on tooth anesthetized with lidocaine with epinephrine caused significantly less increase of PBF than in control tooth (p < 0.05).

Therefore, the result of the present study demonstrates that local infiltration of 2% lidocaine with 1 : 100,000 epinephrine effectively reduces PBF increase caused by cavity preparation.

Citations

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• Systematic Injection Patterned-Technique of One-Per-Mil Tumescent Solution for Perforator-Based Skin Flap: Is it Better Than the Random Patterned-Technique?
  Theddeus O. H. Prasetyono, Sweety Pribadi
  International Surgery.2015; 100(9-10): 1308.     CrossRef
• Biologic response of local hemostatic agents used in endodontic microsurgery
  Youngjune Jang, Hyeon Kim, Byoung-Duck Roh, Euiseong Kim
  Restorative Dentistry & Endodontics.2014; 39(2): 79.     CrossRef
• Change in Pulpal Blood Flow of Heat-induced Neurogenic Inflammation in Feline Dental Plup
  Min-Kyoung Park
  Journal of the Korea Academia-Industrial cooperation Society.2013; 14(12): 6340.     CrossRef
• Cardiovascular effect of epinephrine in endodontic microsurgery: a review
  Youngjune Jang, Euiseong Kim
  Restorative Dentistry & Endodontics.2013; 38(4): 187.     CrossRef