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Case Reports
Accidental injury of the inferior alveolar nerve due to the extrusion of calcium hydroxide in endodontic treatment: a case report
Yooseok Shin, Byoung-Duck Roh, Yemi Kim, Taehyeon Kim, Hyungjun Kim
Restor Dent Endod 2016;41(1):63-67.   Published online January 6, 2016
DOI: https://doi.org/10.5395/rde.2016.41.1.63
AbstractAbstract PDFPubReaderePub

During clinical endodontic treatment, we often find radiopaque filling material beyond the root apex. Accidental extrusion of calcium hydroxide could cause the injury of inferior alveolar nerve, such as paresthesia or continuous inflammatory response. This case report presents the extrusion of calcium hydroxide and treatment procedures including surgical intervention. A 48 yr old female patient experienced Calcipex II extrusion in to the inferior alveolar canal on left mandibular area during endodontic treatment. After completion of endodontic treatment on left mandibular first molar, surgical intervention was planned under general anesthesia. After cortical bone osteotomy and debridement, neuroma resection and neurorrhaphy was performed, and prognosis was observed. But no improvement in sensory nerve was seen following surgical intervention after 20 mon. A clinician should be aware of extrusion of intracanal medicaments and the possibility of damage on inferior alveolar canal. Injectable type of calcium hydroxide should be applied with care for preventing nerve injury. The alternative delivery method such as lentulo spiral was suggested on the posterior mandibular molar.

Citations

Citations to this article as recorded by  
  • Automatic localization of inferior alveolar nerve canal in panoramic dental images
    Uma Maheswari Pandyan, Banumathi Arumugam, Ulaganathan Gurunathan, Shahul Hameed Kopuli Ashkar Ali
    Signal, Image and Video Processing.2022; 16(5): 1389.     CrossRef
  • Inferior alveolar nerve injury due to the extrusion of calcium hydroxide during endodontic treatment: A case report
    Metin Berk Kasapoğlu, Gülce Ecem Doğancalı
    Australian Endodontic Journal.2022; 48(2): 342.     CrossRef
  • Inferior alveolar nerve canal segmentation by local features based neural network model
    P. Uma Maheswari, A. Banumathi, G. Ulaganathan, R. Yoganandha
    IET Image Processing.2022; 16(3): 703.     CrossRef
  • Microsurgical Repair of Inferior Alveolar Nerve Injuries Associated With Endodontic Treatment: Results on Sensory Function and Relief of Pain
    Keith A. Sonneveld, Kristopher L. Hasstedt, Roger A. Meyer, Shahrokh C. Bagheri
    Journal of Oral and Maxillofacial Surgery.2021; 79(7): 1434.     CrossRef
  • The significance of diagnosis and treatment planning in periapical lesion overfilled with calcium hydroxide paste
    Kyoung-Hwa Jung, Eun-Young Kwon, Youn-Kyung Choi, So-Yeun Kim, Hye-Mi Jeon, Jeong-Kil Park
    Journal of Dental Rehabilitation and Applied Science.2021; 37(2): 95.     CrossRef
  • The anatomical relationship between the roots of erupted permanent teeth and the mandibular canal: a systematic review
    Michał Puciło, Mariusz Lipski, Magdalena Sroczyk-Jaszczyńska, Aleksandra Puciło, Alicja Nowicka
    Surgical and Radiologic Anatomy.2020; 42(5): 529.     CrossRef
  • Massive extrusion of calcium hydroxide paste containing barium sulphate during endodontic treatment
    Jéssica Montenegro Fonsêca, Natália Rangel Palmier, Gleyson Kleber Amaral‐Silva, Lady Paola Aristizabal Arboleda, José Flávio Affonso Almeida, Mario Fernando de Goes, Pablo Agustin Vargas, Marcio Ajudarte Lopes, Alan Roger Santos‐Silva
    Australian Endodontic Journal.2020; 46(2): 257.     CrossRef
  • The double-edged sword of calcium hydroxide in endodontics
    Alan H. Gluskin, Gordon Lai, Christine I. Peters, Ove A. Peters
    The Journal of the American Dental Association.2020; 151(5): 317.     CrossRef
  • Endodontic-related inferior alveolar nerve injuries: A review and a therapeutic flow chart
    R. Castro, M. Guivarc'h, J.M. Foletti, J.H. Catherine, C. Chossegros, L. Guyot
    Journal of Stomatology, Oral and Maxillofacial Surgery.2018; 119(5): 412.     CrossRef
  • Relationship between Root Apices and the Mandibular Canal: A Cone-beam Computed Tomographic Comparison of 3 Populations
    Alex Lvovsky, Shir Bachrach, Hyeon-Cheol Kim, Ajinkya Pawar, Oleg Levinzon, Joe Ben Itzhak, Michael Solomonov
    Journal of Endodontics.2018; 44(4): 555.     CrossRef
  • A case of high density abnormality in x-ray findings of mandible caused by leakage of root canal filling paste
    Haruko Kashiwamura, Kyoko Oka, Yoko Tuchihashi, Hanako Yoshioka, Mayumi Kato, Atsuko Baba, Toyohiro Kagawa, Kazuhiko Okamura, Masao Ozaki
    Pediatric Dental Journal.2017; 27(3): 162.     CrossRef
  • Oral dysesthesia
    Christopher J. Spencer, Gary D. Klasser
    The Journal of the American Dental Association.2017; 148(12): 941.     CrossRef
  • Microsurgical Decompression of Inferior Alveolar Nerve After Endodontic Treatment Complications
    Bernardo Bianchi, Andrea Ferri, Andrea Varazzani, Michela Bergonzani, Enrico Sesenna
    Journal of Craniofacial Surgery.2017; 28(5): 1365.     CrossRef
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  • 13 Crossref
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Esthetic rehabilitation of single anterior edentulous space using fiber-reinforced composite
Hyeon Kim, Min-Ju Song, Su-Jung Shin, Yoon Lee, Jeong-Won Park
Restor Dent Endod 2014;39(3):220-225.   Published online May 19, 2014
DOI: https://doi.org/10.5395/rde.2014.39.3.220
AbstractAbstract PDFPubReaderePub

A fiber-reinforced composite (FRC) fixed prosthesis is an innovative alternative to a traditional metal restoration, as it is a conservative treatment method. This case report demonstrates a detailed procedure for restoring a missing anterior tooth with an FRC. A 44-year-old woman visited our department with an avulsed tooth that had fallen out on the previous day and was completely dry. This tooth was replanted, but it failed after one year. A semi-direct technique was used to fabricate a FRC fixed partial prosthesis for its replacement. The FRC framework and the pontic were fabricated using a duplicated cast model and nanofilled composite resin. Later on, interproximal contact, tooth shape, and shade were adjusted at chairside. This technique not only enables the clinician to replace a missing tooth immediately after extraction for minimizing esthetic problems, but it also decreases both tooth reduction and cost.

Citations

Citations to this article as recorded by  
  • Anterior provisional fixed partial dentures: A finite element analysis
    Nouf Almeganni, Rotana Abulaban, Ghada Naguib, Mohamed Tharwat, Hani M. Nassar
    Journal of Prosthodontics.2024; 33(4): 367.     CrossRef
  • FİBERLE GÜÇLENDİRİLMİŞ ADEZİV KÖPRÜLER VE UYGULAMA YÖNTEMLERİ
    Gözde YALÇIN, Asude Dilek NALBANT
    Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2022; : 1.     CrossRef
  • Fiber-reinforced composite resin bridges: an alternative method to treat root-fractured teeth
    Gun Heo, Eun-Hye Lee, Jin-Woo Kim, Kyung-Mo Cho, Se-Hee Park
    Restorative Dentistry & Endodontics.2020;[Epub]     CrossRef
  • A New Technique for Direct Fabrication of Fiber-Reinforced Composite Bridge: A Long-Term Clinical Observation
    Matías Ferrán Escobedo Martínez, Samuel Rodríguez López, Jairo Valdés Fontela, Sonsoles Olay García, Mario Mauvezín Quevedo
    Dentistry Journal.2020; 8(2): 48.     CrossRef
  • Customized Treatment Option for Malpositioned Dental Implant Placed in Aesthetic Zone
    Priyanka N. Khungar, Trupti M. Dahane, Ramnath P. Revankar, Rupali Patel
    Journal of Evolution of Medical and Dental Sciences.2020; 9(39): 2930.     CrossRef
  • Fiber reinforced composite bridge as a replacement for missing upper permanent lateral incisor – a case report
    Ana Todorović, Danica Popović, Igor Djordjević, Vojkan Lazić
    Stomatoloski glasnik Srbije.2016; 63(3): 133.     CrossRef
  • Evaluation of the Viability of Rat Periodontal Ligament Cells after Storing at 0℃/2 MPa Condition up to One Week: In Vivo MTT Method
    Sun Mi Jang, Sin-Yeon Cho, Eui-Seong Kim, Il-Young Jung, Seung Jong Lee
    Journal of Korean Dental Science.2016; 9(1): 1.     CrossRef
  • Semidirect Restorations in Multidisciplinary Treatment: Viable Option for Children and Teenagers
    Mateus Rodrigues Tonetto, Milton Carlos Kuga, Fausto Frizzera, Matheus Coelho Bandeca, Shilpa H Bhandi, Célia Regina Maio Pinzan-Vercelino, Monica Barros da Silva, Kamila Figueiredo Pereira
    The Journal of Contemporary Dental Practice.2015; 16(4): 280.     CrossRef
  • 261 View
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  • 8 Crossref
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Review Article
Biologic response of local hemostatic agents used in endodontic microsurgery
Youngjune Jang, Hyeon Kim, Byoung-Duck Roh, Euiseong Kim
Restor Dent Endod 2014;39(2):79-88.   Published online March 21, 2014
DOI: https://doi.org/10.5395/rde.2014.39.2.79
AbstractAbstract PDFPubReaderePub

Appropriate use of local hemostatic agent is one of the important factors on the prognosis of endodontic microsurgery. However, most investigations to date focus on the hemostatic efficacy of the agents, whereas their biologic characteristics have not received enough attention. The purpose of this paper was to review the biologic response of local hemostatic agents, and to provide clinical guidelines on their use during endodontic microsurgery. Electronic database (PUBMED) was screened to search related studies from 1980 to 2013, and 8 clinical studies and 18 animal studies were identified. Among the materials used in these studies, most widely-investigated and used materials, epinephrine, ferric sulfate (FS) and calcium sulfate (CS), were thoroughly discussed. Influence of these materials on local tissue and systemic condition, such as inflammatory and foreign body reaction, local ischemia, dyspigmentation, delayed or enhanced bone and soft tissue healing, and potential cardiovascular complications were assessed. Additionally, biological property of their carrier materials, cotton pellet and absorbable collagen, were also discussed. Clinicians should be aware of the biologic properties of local hemostatic agents and their carrier materials, and should pay attention to the potential complications when using them in endodontic microsurgery.

Citations

Citations to this article as recorded by  
  • Expert consensus on apical microsurgery
    Hanguo Wang, Xin Xu, Zhuan Bian, Jingping Liang, Zhi Chen, Benxiang Hou, Lihong Qiu, Wenxia Chen, Xi Wei, Kaijin Hu, Qintao Wang, Zuhua Wang, Jiyao Li, Dingming Huang, Xiaoyan Wang, Zhengwei Huang, Liuyan Meng, Chen Zhang, Fangfang Xie, Di Yang, Jinhua Yu
    International Journal of Oral Science.2025;[Epub]     CrossRef
  • Assessing the efficacy of apicoectomy without retrograde filling in treating periapical inflammatory cysts
    Jeong-Kui Ku, Woo-Young Jeon, Seung-O Ko, Ji-Young Yoon
    Journal of the Korean Association of Oral and Maxillofacial Surgeons.2024; 50(3): 140.     CrossRef
  • Functional and structural neurodegenerative activities of Ankaferd BloodStopper in a mouse sciatic nerve model
    Ramazan Üstün, Elif Oğuz, Ayşe Şeker, Filiz Taspinar
    Experimental and Therapeutic Medicine.2024;[Epub]     CrossRef
  • Local and Systemic Hemostatic Agents: A Comprehensive Review
    Bardia Jamali, Saeed Nouri, Salimeh Amidi
    Cureus.2024;[Epub]     CrossRef
  • PLGA Nanoparticle Rapamycin- or Necrostatin-1-Coated Sutures Inhibit Inflammatory Reactions after Arterial Closure in Rats
    Liwei Zhang, Wang Wang, Boao Xie, Peng Sun, Shunbo Wei, Haoliang Wu, Cong Zhang, Jingan Li, Zhuo Li, Hualong Bai
    ACS Applied Bio Materials.2022; 5(4): 1501.     CrossRef
  • COMPARING THE CLINICAL AND RADIOGRAPHIC OUTCOMES OF PULPOTOMIES IN PRIMARY MOLARS USING BIOACTIVE ENDODONTIC MATERIALS AND FERRIC SULFATE – A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS
    VELLORE KANNAN GOPINATH, SHAJU JACOB PULIKKOTIL, SAJESH K VEETTIL, LALLI DHARMARAJAN, PONNUDURAI SAMUEL GNANA PRAKASH, VINEET DHAR, JAYAKUMAR JAYARAMAN
    Journal of Evidence-Based Dental Practice.2022; 22(4): 101770.     CrossRef
  • Perioperative Antiplatelet and Anticoagulant Management with Endodontic Microsurgical Techniques
    Anita Aminoshariae, Mark Donaldson, Michael Horan, James C. Kulild, Dale Baur
    Journal of Endodontics.2021; 47(10): 1557.     CrossRef
  • Effect of blood contamination and various hemostatic procedures on the push-out bond strength of Biodentine when used for furcation perforation repair
    Shanthana Reddy, Ramya Shenoy, LohithReddy Mandadi, Ishani Saluja, ManuelS Thomas
    Journal of Conservative Dentistry.2021; 24(3): 260.     CrossRef
  • Endodontic Perforation Closure by Five Mineral Oxides Silicate-Based Cement with/without Collagen Sponge Matrix
    Talal Al-Nahlawi, Maisour Ala Rachi, Amjad Abu Hasna, Zohaib Khurshid
    International Journal of Dentistry.2021; 2021: 1.     CrossRef
  • Hemostatic agents in periapical surgery: The systematic review
    Z. S. Khabadze, D. A. Nazarova, E. S. Shilyaeva, A. P. Kotelnikova, Yu. A. Bakayev, S. M. Abdulkerimova, Kh. O. Omarova
    Endodontics Today.2021; 19(3): 184.     CrossRef
  • An Innovative Bioceramic Bone Graft Substitute for Bone Defect Treatment: In Vivo Evaluation of Bone Healing
    Syamsiah Syam, Yung-Chieh Cho, Chung-Ming Liu, Mao-Suan Huang, Wen-Chien Lan, Bai-Hung Huang, Takaaki Ueno, Chi-Hsun Tsai, Takashi Saito, May-Show Chen, Keng-Liang Ou
    Applied Sciences.2020; 10(22): 8303.     CrossRef
  • Trial finds better haemostasis with aluminium chloride during periapical surgery
    Niall Mc Goldrick, Carly Ross, James Nelson
    Evidence-Based Dentistry.2017; 18(2): 50.     CrossRef
  • Comparison of the Hemostatic Activity of Quercus persica Jaub. & Spach. (Oak) With Ferric Sulfate in Bony Crypts
    Mohammad Reza Nabavizadeh, Arman Zargaran, Fariborz Moazami, Fatemeh Askari, Safoora Sahebi, Alireza Farhadpoor, Pouya Faridi
    Journal of Evidence-Based Complementary & Alternative Medicine.2016; 21(1): 34.     CrossRef
  • Effect of the plant-based hemostatic agent Ankaferd Blood Stopper® on the biocompatibility of mineral trioxide aggregate
    Muzaffer Emir Dinçol, Hakan Ozbas, Bulent Yılmaz, Handan Ersev, Selcuk Gokyay, Vakur Olgac
    BMC Oral Health.2016;[Epub]     CrossRef
  • 329 View
  • 3 Download
  • 14 Crossref
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Research Article
Inhibition of Streptococcus mutans biofilm formation on composite resins containing ursolic acid
Soohyeon Kim, Minju Song, Byoung-Duck Roh, Sung-Ho Park, Jeong-Won Park
Restor Dent Endod 2013;38(2):65-72.   Published online May 28, 2013
DOI: https://doi.org/10.5395/rde.2013.38.2.65
AbstractAbstract PDFPubReaderePub
Objectives

To evaluate the inhibitory effect of ursolic acid (UA)-containing composites on Streptococcus mutans (S. mutans) biofilm.

Materials and Methods

Composite resins with five different concentrations (0.04, 0.1, 0.2, 0.5, and 1.0 wt%) of UA (U6753, Sigma Aldrich) were prepared, and their flexural strengths were measured according to ISO 4049. To evaluate the effect of carbohydrate source on biofilm formation, either glucose or sucrose was used as a nutrient source, and to investigate the effect of saliva treatment, the specimen were treated with either unstimulated whole saliva or phosphate-buffered saline (PBS). For biofilm assay, composite disks were transferred to S. mutans suspension and incubated for 24 hr. Afterwards, the specimens were rinsed with PBS and sonicated. The colony forming units (CFU) of the disrupted biofilm cultures were enumerated. For growth inhibition test, the composites were placed on a polystyrene well cluster, and S. mutans suspension was inoculated. The optical density at 600 nm (OD600) was recorded by Infinite F200 pro apparatus (TECAN). One-way ANOVA and two-way ANOVA followed by Bonferroni correction were used for the data analyses.

Results

The flexural strength values did not show significant difference at any concentration (p > 0.01). In biofilm assay, the CFU score decreased as the concentration of UA increased. The influence of saliva pretreatment was conflicting. The sucrose groups exhibited higher CFU score than glucose group (p < 0.05). In bacterial growth inhibition test, all experimental groups containing UA resulted in complete inhibition.

Conclusions

Within the limitations of the experiments, UA included in the composite showed inhibitory effect on S. mutans biofilm formation and growth.

Citations

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  • Anti-cariogenic effect of experimental resin cement containing ursolic acid using dental microcosm biofilm
    Jonghyun Jo, Mi-Jeong Jeon, Sun Kyu Park, Su-Jung Shin, Baek-il Kim, Jeong-Won Park
    Journal of Dentistry.2024; 151: 105447.     CrossRef
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    Jett Liu, Camden Carmichael, Hatice Hasturk, Wenyuan Shi, Batbileg Bor
    Journal of Oral Microbiology.2023;[Epub]     CrossRef
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    Bioengineering.2023; 10(9): 991.     CrossRef
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    Fitoterapia.2023; 167: 105508.     CrossRef
  • The Application of Small Molecules to the Control of Typical Species Associated With Oral Infectious Diseases
    Sirui Yang, Xiaoying Lyu, Jin Zhang, Yusen Shui, Ran Yang, Xin Xu
    Frontiers in Cellular and Infection Microbiology.2022;[Epub]     CrossRef
  • Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals
    Zuzanna Sycz, Dorota Tichaczek-Goska, Dorota Wojnicz
    Biomolecules.2022; 12(1): 98.     CrossRef
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    Maury Luz Pereira, Danyelle Cristina Pereira Santos, Carlos Alberto Mendes Soares Júnior, Tamyris Alicely Xavier Nogueira Bazan, Clovis Macêdo Bezerra Filho, Márcia Vanusa da Silva, Maria Tereza dos Santos Correia, Andres Felipe Millan Cardenas, Fabiana S
    Journal of Functional Biomaterials.2022; 13(3): 149.     CrossRef
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    Pharmaceutics.2022; 14(8): 1691.     CrossRef
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    International Journal of Dentistry.2022; 2022: 1.     CrossRef
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    Annual Review of Phytopathology.2021; 59(1): 153.     CrossRef
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    Pathogens.2021; 10(12): 1540.     CrossRef
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    Brazilian Oral Research.2021;[Epub]     CrossRef
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    Antibiotics.2021; 10(11): 1381.     CrossRef
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    Dental Materials.2014; 30(2): e1.     CrossRef
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  • Synergistic effect of xylitol and ursolic acid combination on oral biofilms
    Yunyun Zou, Yoon Lee, Jinyoung Huh, Jeong-Won Park
    Restorative Dentistry & Endodontics.2014; 39(4): 288.     CrossRef
  • The virulence of Streptococcus mutans and the ability to form biofilms
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