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Yeong-Joon Park 4 Articles
Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials
Young-Eun Jang, Bin-Na Lee, Jeong-Tae Koh, Yeong-Joon Park, Nam-Eok Joo, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
Restor Dent Endod 2014;39(2):89-94.   Published online March 21, 2014
DOI: https://doi.org/10.5395/rde.2014.39.2.89
AbstractAbstract PDFPubReaderePub
Objectives

The aim of this study was to evaluate the cytotoxicity, setting time and compressive strength of MTA and two novel tricalcium silicate-based endodontic materials, Bioaggregate (BA) and Biodentine (BD).

Materials and Methods

Cytotoxicity was evaluated by using a 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide (XTT) assay. Measurements of 9 heavy metals (arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel, and zinc) were performed by inductively coupled plasma-mass spectrometry (ICP-MS) of leachates obtained by soaking the materials in distilled water. Setting time and compressive strength tests were performed following ISO requirements.

Results

BA had comparable cell viability to MTA, whereas the cell viability of BD was significantly lower than that of MTA. The ICP-MS analysis revealed that BD released significantly higher amount of 5 heavy metals (arsenic, copper, iron, manganese, and zinc) than MTA and BA. The setting time of BD was significantly shorter than that of MTA and BA, and the compressive strength of BA was significantly lower than that of MTA and BD.

Conclusions

BA and BD were biocompatible, and they did not show any cytotoxic effects on human periodontal ligament fibroblasts. BA showed comparable cytotoxicity to MTA but inferior physical properties. BD had somewhat higher cytotoxicity but superior physical properties than MTA.

Citations

Citations to this article as recorded by  
  • Evaluation of the physical properties of bromelain-modified biodentine for direct pulp capping
    Paridhi Agrawal, Manoj Chandak, Aditya Patel, Jay Bhopatkar
    BMC Oral Health.2024;[Epub]     CrossRef
  • Evaluation of bioactivity, biocompatibility, and antibacterial properties of tricalcium silicate bone cement modified with wollastonite/ fluorapatite glass and glass-ceramic
    H.K. Abd El-Hamid, A.M. Fayad, R.L. Elwan
    Ceramics International.2024; 50(14): 25322.     CrossRef
  • Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study
    Monthip Wannakajeepiboon, Chankhrit Sathorn, Chatvadee Kornsuthisopon, Busayarat Santiwong, Thanakorn Wasanapiarnpong, Pairoj Linsuwanont
    BMC Oral Health.2023;[Epub]     CrossRef
  • Strength of a cement-based dental material: Early age testing and first micromechanical modeling at mature age
    Petr Dohnalík, Christian Hellmich, Gilles Richard, Bernhard L. A. Pichler
    Frontiers in Bioengineering and Biotechnology.2023;[Epub]     CrossRef
  • Calcium silicate and calcium aluminate cements for dentistry reviewed
    Carolyn Primus, James L. Gutmann, Franklin R. Tay, Anna B. Fuks
    Journal of the American Ceramic Society.2022; 105(3): 1841.     CrossRef
  • Biomimetic Approaches in Clinical Endodontics
    Naresh Kumar, Nazrah Maher, Faiza Amin, Hani Ghabbani, Muhammad Sohail Zafar, Francisco Javier Rodríguez-Lozano, Ricardo E. Oñate-Sánchez
    Biomimetics.2022; 7(4): 229.     CrossRef
  • Effect of different manipulations on the physical, chemical and microstructural characteristics of Biodentine
    Mariana Domingos Pires, Joana Cordeiro, Isabel Vasconcelos, Mariana Alves, Sérgio André Quaresma, António Ginjeira, Josette Camilleri
    Dental Materials.2021; 37(7): e399.     CrossRef
  • Minimal Intervention in Dentistry: A Literature Review on Biodentine as a Bioactive Pulp Capping Material
    Naji Ziad Arandi, Mohammad Thabet, Mona Abbassy
    BioMed Research International.2021;[Epub]     CrossRef
  • Chitosan-Based Accelerated Portland Cement Promotes Dentinogenic/Osteogenic Differentiation and Mineralization Activity of SHED
    Hasan Subhi, Adam Husein, Dasmawati Mohamad, Nik Rozainah Nik Abdul Ghani, Asma-Abdullah Nurul
    Polymers.2021; 13(19): 3358.     CrossRef
  • Material Pulp Cells and Tissue Interactions
    Nastaran Meschi, Biraj Patel, Nikita B. Ruparel
    Journal of Endodontics.2020; 46(9): S150.     CrossRef
  • Biological Effects of Tricalcium Silicate Nanoparticle-Containing Cement on Stem Cells from Human Exfoliated Deciduous Teeth
    Yoonsun Jung, Ji-Young Yoon, Kapil Dev Patel, Lan Ma, Hae-Hyoung Lee, Jongbin Kim, Jung-Hwan Lee, Jisun Shin
    Nanomaterials.2020; 10(7): 1373.     CrossRef
  • Physicochemical, mechanical and cytotoxicity evaluation of chitosan-based accelerated portland cement
    Hasan Subhi, Adam Husein, Dasmawati Mohamad, Asma-Abdullah Nurul
    Journal of Materials Research and Technology.2020; 9(5): 11574.     CrossRef
  • Tricalcium silicate cements: osteogenic and angiogenic responses of human bone marrow stem cells
    Mohamed R. W. Ali, Manal Mustafa, Asgeir Bårdsen, Athanasia Bletsa
    European Journal of Oral Sciences.2019; 127(3): 261.     CrossRef
  • Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues
    Carolyn M. Primus, Franklin R. Tay, Li-na Niu
    Acta Biomaterialia.2019; 96: 35.     CrossRef
  • Effect of phytic acid on the setting times and tensile strengths of calcium silicate‐based cements
    Ozgur Uyanik, Emre Nagas, Selen Kucukkaya Eren, Zafer C. Cehreli, Pekka K. Vallittu, Lippo V.J. Lassila
    Australian Endodontic Journal.2019; 45(2): 241.     CrossRef
  • Effects of four novel root-end filling materials on the viability of periodontal ligament fibroblasts
    Makbule Bilge Akbulut, Pembegul Uyar Arpaci, Ayce Unverdi Eldeniz
    Restorative Dentistry & Endodontics.2018;[Epub]     CrossRef
  • Biodentine™ material characteristics and clinical applications: a 3 year literature review and update
    S. Rajasekharan, L. C. Martens, R. G. E. C. Cauwels, R. P. Anthonappa
    European Archives of Paediatric Dentistry.2018; 19(1): 1.     CrossRef
  • Root perforations: a review of diagnosis, prognosis and materials
    Carlos Estrela, Daniel de Almeida Decurcio, Giampiero Rossi-Fedele, Julio Almeida Silva, Orlando Aguirre Guedes, Álvaro Henrique Borges
    Brazilian Oral Research.2018;[Epub]     CrossRef
  • Effects of chelating agent and acids on Biodentine
    V Ballal, JN Marques, CN Campos, CO Lima, RA Simão, M Prado
    Australian Dental Journal.2018; 63(2): 170.     CrossRef
  • Biological interactions of a calcium silicate based cement (Biodentine™) with Stem Cells from Human Exfoliated Deciduous teeth
    Eirini Athanasiadou, Maria Paschalidou, Anna Theocharidou, Nikolaos Kontoudakis, Konstantinos Arapostathis, Athina Bakopoulou
    Dental Materials.2018; 34(12): 1797.     CrossRef
  • Retention of BioAggregate and MTA as coronal plugs after intracanal medication for regenerative endodontic procedures: an ex vivo study
    Suzan Abdul Wanees Amin, Shaimaa Ismail Gawdat
    Restorative Dentistry & Endodontics.2018;[Epub]     CrossRef
  • Management of Dens Invaginatus Type II Associated with Immature Apex and Large Periradicular Lesion Using Platelet-rich Fibrin and Biodentine
    Shruti Goel, Ruchika Roongta Nawal, Sangeeta Talwar
    Journal of Endodontics.2017; 43(10): 1750.     CrossRef
  • Brain aluminium accumulation and oxidative stress in the presence of calcium silicate dental cements
    K Demirkaya, B Can Demirdöğen, Z Öncel Torun, O Erdem, E Çırak, YM Tunca
    Human & Experimental Toxicology.2017; 36(10): 1071.     CrossRef
  • Calcium silicate‐based cements: composition, properties, and clinical applications
    Alaa E. Dawood, Peter Parashos, Rebecca H.K. Wong, Eric C. Reynolds, David J. Manton
    Journal of Investigative and Clinical Dentistry.2017;[Epub]     CrossRef
  • Biological response of commercially available different tricalcium silicate-based cements and pozzolan cement
    Serhat Köseoğlu, Tuğba Pekbağryank, Ebru Kucukyilmaz, Mehmet Sağlam, Sukru Enhos, Ayşe Akgün
    Microscopy Research and Technique.2017; 80(9): 994.     CrossRef
  • Modified tricalcium silicate cement formulations with added zirconium oxide
    Xin Li, Kumiko Yoshihara, Jan De Munck, Stevan Cokic, Pong Pongprueksa, Eveline Putzeys, Mariano Pedano, Zhi Chen, Kirsten Van Landuyt, Bart Van Meerbeek
    Clinical Oral Investigations.2017; 21(3): 895.     CrossRef
  • Cytotoxic effects of mineral trioxide aggregate, calcium enrichedmixture cement, Biodentine and octacalcium pohosphate onhuman gingival fibroblasts
    Eshagh A. Saberi, Narges Farhadmollashahi, Faroogh Ghotbi, Hamed Karkeabadi, Roholla Havaei
    Journal of Dental Research, Dental Clinics, Dental Prospects.2016; 10(2): 75.     CrossRef
  • The effect of working time on the displacement of Biodentine™ beneath prefabricated stainless steel crown: a laboratory study
    Alaa E. Dawood, David J. Manton, Peter Parashos, Rebecca H. K. Wong
    Journal of Investigative and Clinical Dentistry.2016; 7(4): 391.     CrossRef
  • Evaluation of reparative dentin formation of ProRoot MTA, Biodentine and BioAggregate using micro-CT and immunohistochemistry
    Jia Kim, Young-Sang Song, Kyung-San Min, Sun-Hun Kim, Jeong-Tae Koh, Bin-Na Lee, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
    Restorative Dentistry & Endodontics.2016; 41(1): 29.     CrossRef
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The effects of short-term application of calcium hydroxide on dentin fracture strength
Eun-Jung Shin, Yeong-Joon Park, Bin-Na Lee, Ji-Hyun Jang, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
J Korean Acad Conserv Dent 2011;36(5):425-430.   Published online September 30, 2011
DOI: https://doi.org/10.5395/JKACD.2011.36.5.425
AbstractAbstract PDFPubReaderePub
Objectives

This in vitro study investigated whether short-term application of calcium hydroxide in the root canal system for 1 and 4 wk affects the fracture strength of human permanent teeth.

Materials and Methods

Thirty two mature human single rooted mandibular premolars in similar size and dentin thickness without decay or restorations were hand and rotary instrumented and 16 teeth vertically packed with calcium hydroxide paste and sealed coronally with caviton to imitate the endodontic procedure and the other 16 teeth was left empty as a control group. The apicies of all the samples were sealed with resin, submerged in normal saline and put in a storage box at 37℃ to mimic the oral environment. After 1 and 4 wk, 8 samples out of 16 samples from each group were removed from the storage box and fracture strength test was performed. The maximum load required to fracture the samples was recorded and data were analysed statistically by the two way ANOVA test at 5% significance level.

Results

The mean fracture strengths of two groups after 1 wk and 4 wk were similar. The intracanal placement of calcium hydroxide weakened the fracture strength of teeth by 8.2% after 4 wk: an average of 39.23 MPa for no treatment group and 36.01 MPa for CH group. However there was no statistically significant difference between experimental groups and between time intervals.

Conclusions

These results suggest that short term calcium hydroxide application is available during endodontic treatment.

Citations

Citations to this article as recorded by  
  • Effect of Calcium Hydroxide as an Intracanal Medication on Dentine Fracture Resistance: A Systematic Review and Network Meta-Analysis
    Chayanit Sunlakawit, Chitpol Chaimanakarn, Natchalee Srimaneekarn, Sittichoke Osiri
    Journal of Endodontics.2024; 50(12): 1714.     CrossRef
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Physical and chemical properties of experimental mixture of mineral trioxide aggregate and glass ionomer cement
Yu-Na Jeong, So-Young Yang, Bum-Jun Park, Yeong-Joon Park, Yun-Chan Hwang, In-Nam Hwang, Won-Mann Oh
J Korean Acad Conserv Dent 2010;35(5):344-352.   Published online September 30, 2010
DOI: https://doi.org/10.5395/JKACD.2010.35.5.344
AbstractAbstract PDFPubReaderePub
Objectives

The purpose of this study was to determine the setting time, compressive strength, solubility, and pH of mineral trioxide aggregate (MTA) mixed with glass ionomer cement (GIC) and to compare these properties with those of MTA, GIC, IRM, and SuperEBA.

Materials and Methods

Setting time, compressive strength, and solubility were determined according to the ISO 9917 or 6876 method. The pH of the test materials was determined using a pH meter with specified electrode for solid specimen.

Results

The setting time of MTA mixed with GIC was significantly shorter than that of MTA. Compressive strength of MTA mixed with GIC was significantly lower than that of other materials at all time points for 7 days. Solubility of 1 : 1 and 2 : 1 specimen from MTA mixed with GIC was significantly higher than that of other materials. Solubility of 1 : 2 specimen was similar to that of MTA. The pH of MTA mixed with GIC was 2-4 immediately after mixing and increased to 5-7 after 1 day.

Conclusions

The setting time of MTA mixed with GIC was improved compared with MTA. However, other properties such as compressive strength and pH proved to be inferior to those of MTA. To be clinically feasible, further investigation is necessary to find the proper mixing ratio in order to improve the drawbacks of MTA without impairing the pre-existing advantages and to assess the biocompatibility.

Citations

Citations to this article as recorded by  
  • Comparison of Setting Time, Compressive Strength, Solubility, and pH of Four Kinds of MTA
    Jing-Ling Che, Jae-Hwan Kim, Seon-Mi Kim, Nam-ki Choi, Hyun-Joo Moon, Moon-Jin Hwang, Ho-Jun Song, Yeong-Joon Park
    Korean Journal of Dental Materials.2016; 43(1): 61.     CrossRef
  • Do conventional glass ionomer cements release more fluoride than resin-modified glass ionomer cements?
    Maria Fernanda Costa Cabral, Roberto Luiz de Menezes Martinho, Manoel Valcácio Guedes-Neto, Maria Augusta Bessa Rebelo, Danielson Guedes Pontes, Flávia Cohen-Carneiro
    Restorative Dentistry & Endodontics.2015; 40(3): 209.     CrossRef
  • Synthesis and Properties of a New Dental Material Based on Nano‐Structured Highly Active Calcium Silicates and Calcium Carbonates
    Vukoman Jokanović, Božana Čolović, Miodrag Mitrić, Dejan Marković, Bojana Ćetenović
    International Journal of Applied Ceramic Technology.2014; 11(1): 57.     CrossRef
  • Evaluation of the effect of blood contamination on the compressive strength of MTA modified with hydration accelerators
    Kaveh Oloomi, Eshaghali Saberi, Hadi Mokhtari, Hamid Reza Mokhtari Zonouzi, Ali Nosrat, Mohammad Hossein Nekoofar, Paul Michael Howell Dummer
    Restorative Dentistry & Endodontics.2013; 38(3): 128.     CrossRef
  • Endodontic management of a maxillary lateral incisor with dens invaginatus and external root irregularity using cone-beam computed tomography
    Young-Jun Lim, Sook-Hyun Nam, Sung-Ho Jung, Dong-Ryul Shin, Su-Jung Shin, Kyung-San Min
    Restorative Dentistry & Endodontics.2012; 37(1): 50.     CrossRef
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Bleaching effect of carbamide peroxide gel on discolored nonvital teeth
Sun-Ah Park, Sun-Ho Kim, Yun-Chan Hwang, Byung-Ju Oh, Chang Youn, Yeong-Joon Park, Sun-Wa Jeong, In-Nam Hwang, Won-Mann Oh
J Korean Acad Conserv Dent 2002;27(4):441-447.   Published online July 31, 2002
DOI: https://doi.org/10.5395/JKACD.2002.27.4.441
AbstractAbstract PDFPubReaderePub

The bleaching of discolored nonvital teeth is conservative treatment that satisfy the cosmetic desire. The most common method for this treatment, walking bleaching, is using 30% hydrogen peroxide and sodium perborate.

Many alternatives are suggested for preventing the external cervical root resorption that is the common complication of the nonvital teeth bleaching with 30% hydrogen peroxide.

The same extent of oxidation reactions as that resulted by the bleaching with the application of 30% hydrogen peroxide and sodium perborate can also be acquired more safely by materials that contain 10% carbamide peroxide, used primarily for the bleaching of vital teeth. Therefore, this study was performed to evaluate the efficacy of 10% and 15% carbamide peroxide bleaching gel in nonvatal teeth bleaching.

The internal bleaching of intentionally discolored teeth was performed in vitro with 10% carbamide peroxide (Group 1), 15% carbamide peroxide (Group 2), mixture of distilled water and sodium perborate (Group 3), and mixture of 30% hydrogen peroxide and sodium perborate (Group 4). The bleaching materials were refreshed following 3, 6, 9 and 12 days. To evaluate the bleaching effect, the color change of the crowns was measured at 1, 2, 3, 4, 7 and 15 days of bleaching using the colorimeter.

The results were as follows :

1. L* and ΔE* values were increased with time in all bleaching agents(p<0.01).

2. There was no significant difference in L* and ΔE* value among bleaching agents.

3. ΔE* value higher than 3 was shown after 3 days of bleaching with 10% carbamide peroxide gel, 1 day with 15% carbamide peroxide gel, 4 days with mixture sodium perborate and distilled water and 4 days with mixture sodium perborate and 30% hydrogen peroxide, respectively.

These results revealed that the use of 10% and 15% carbamide peroxide bleaching gel in non-vital teeth bleaching is as effective as mixture of distilled water and sodium perborate and mixture of 30% hydrogen peroxide and sodium perborate. Accordingly, carbamide peroxide could be used clinically to bleach discolored non-vital teeth.

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