The purpose of a root-end filling is to establish a seal between the root canal space and the periradicular tissues. As root-end filling materials come into contact with periradicular tissues, knowledge of the tissue response is crucial. Almost every available dental restorative material has been suggested as the root-end material of choice at a certain point in the past. This literature review on root-end filling materials will evaluate and comparatively analyse the biocompatibility and tissue response to these products, with primary focus on newly introduced materials.

Citations

Citations to this article as recorded by  

• MTA as modulator of periapical tissue healing in rat molar: A histological study
  Christian Khoswanto, Ira Kusuma Dewi
  Journal of Oral Biology and Craniofacial Research.2024; 14(2): 201.     CrossRef
• Effects of Three Retrograde Filling Materials on Production of Inflammatory Cytokines and Resorbing Mediators
  Samaneh Arab, Marjan Bahraminasab, Masoumeh Motamedi, Jamshid Hadjati, Alaviye Vahid
  Journal of Microbiota.2024;[Epub]     CrossRef
• An in vitro assessment of cytotoxicity and genotoxicity of root repair materials
  Shreya A. Harti, M. S. Adarsha, N. Meena, N. S. Priya, L. Vijayalakshmi, Akshata J. Airsang
  Journal of Oral and Maxillofacial Pathology.2023; 27(4): 700.     CrossRef
• In Vitro Comparison of Differences in Setting Time of Premixed Calcium Silicate-Based Mineral Trioxide Aggregate According to Moisture Content of Gypsum
  Hyun-Jin Kim, Jun-Seok Lee, Dong-Hoon Gwak, Yong-Seok Ko, Chun-Il Lim, Seung-Youl Lee
  Materials.2023; 17(1): 35.     CrossRef
• An in-vitro comparison of bond strength of three different root end filling materials with Universal testing machine
  Vandana Goyal, Iyana Garg, Parminder Kaur, Ankita Tomar
  IP Indian Journal of Conservative and Endodontics.2023; 8(4): 221.     CrossRef
• Push-out bond strength and intratubular biomineralization of a hydraulic root-end filling material premixed with dimethyl sulfoxide as a vehicle
  Ju-Ha Park, Hee-Jin Kim, Kwang-Won Lee, Mi-Kyung Yu, Kyung-San Min
  Restorative Dentistry & Endodontics.2023;[Epub]     CrossRef
• A Systematic Review on Comparison of Periapical Healing and Post-Operative Pain between Bioceramic and Epoxy Resin Based Sealers
  Deepali Mahajan, Devansh Manocha, Priyesha Patel, Maulik B. Saraiya, Keral Chaniyara
  Journal of Pharmacy and Bioallied Sciences.2023; 15(Suppl 2): S862.     CrossRef
• Periapical Healing following Root Canal Treatment Using Different Endodontic Sealers: A Systematic Review
  Akshay Khandelwal, Krishnamachari Janani, KavalipurapuVenkata Teja, Jerry Jose, Gopi Battineni, Francesco Riccitiello, Alessandra Valletta, Ajitha Palanivelu, Gianrico Spagnuolo, Vincenzo Grassia
  BioMed Research International.2022;[Epub]     CrossRef
• Confocal laser scanning microscopic evaluation of sealing ability of bone cement, mineral trioxide aggregate and biodentine as root-end filling materials
  Shalin Ann Saji, Tony Mathew, Aditya Shetty, Gurmeen Kaur, Sunheri Bajpe
  Endodontology.2022; 34(2): 86.     CrossRef
• Adhesive Ability of Different Oral Pathogens to Various Dental Materials: An In Vitro Study
  Yan Tu, Shuli Deng, Yuan Wang, Xiaolong Lin, Zhenyu Yang, Tingtao Chen
  Canadian Journal of Infectious Diseases and Medical Microbiology.2022; 2022: 1.     CrossRef
• Fast self-curing α-tricalcium phosphate/β-dicalcium silicate composites beneficial for root canal sealing treatment
  Youyang Zheng, Xianyan Yang, Shuxin Liu, Siqi Bao, Yuyue Xu, Yunyi Wang, Feng Zhang, Zhongru Gou
  Heliyon.2022; 8(9): e10713.     CrossRef
• Pleiotropic Effects of Eugenol: The Good, the Bad, and the Unknown
  Oana M. Aburel, Ioana Z. Pavel, Maria D. Dănilă, Theia Lelcu, Alexandra Roi, Rodica Lighezan, Danina M. Muntean, Laura C. Rusu, M rcio Carocho
  Oxidative Medicine and Cellular Longevity.2021;[Epub]     CrossRef
• Novel nanosystems to enhance biological activity of hydroxyapatite against dental caries
  Nataliya Babayevska, Marta Woźniak-Budych, Jagoda Litowczenko, Barbara Peplińska, Marcin Jarek, Patryk Florczak, Grażyna Bartkowiak, Beata Czarnecka, Stefan Jurga
  Materials Science and Engineering: C.2021; 124: 112062.     CrossRef
• Comparison of the sealing ability of various bioceramic materials for endodontic surgery
  Benjamin Rencher, Ana M. Chang, Hanson Fong, James D. Johnson, Avina Paranjpe
  Restorative Dentistry & Endodontics.2021;[Epub]     CrossRef
• Scanning electron microscopy analysis of marginal adaptation of mineral trioxide aggregate, tricalcium silicate cement, and dental amalgam as a root end filling materials
  Lena Z. Jovanović, Branislav V. Bajkin
  Microscopy Research and Technique.2021; 84(9): 2068.     CrossRef
• Assessment of bone healing after mineral trioxide aggregate and platelet-rich fibrin application in periapical lesions using cone-beam computed tomographic imaging
  Nazife Begüm Karan, Banu Aricioğlu
  Clinical Oral Investigations.2020; 24(2): 1065.     CrossRef
• Micro-computed tomographic evaluation of the flow and filling ability of endodontic materials using different test models
  Fernanda Ferrari Esteves Torres, Juliane Maria Guerreiro-Tanomaru, Gisselle Moraima Chavez-Andrade, Jader Camilo Pinto, Fábio Luiz Camargo Villela Berbert, Mario Tanomaru-Filho
  Restorative Dentistry & Endodontics.2020;[Epub]     CrossRef
• Investigating unset endodontic sealers’ eugenol and hydrocortisone roles in modulating the initial steps of inflammation
  Charlotte Jeanneau, Thomas Giraud, Jean-Louis Milan, Imad About
  Clinical Oral Investigations.2020; 24(2): 639.     CrossRef
• Tricalcium silicate cements: osteogenic and angiogenic responses of human bone marrow stem cells
  Mohamed R. W. Ali, Manal Mustafa, Asgeir Bårdsen, Athanasia Bletsa
  European Journal of Oral Sciences.2019; 127(3): 261.     CrossRef
• Systemic bone marker expression induced by grey and white mineral trioxide aggregate in normal and diabetic conditions
  I. O. de Azevedo Queiroz, W. G. Mello, C. M. Martins, R. Dal Fabbro, L. G. Narciso, L. Massunari, L. T. A. Cintra, E. Ervolino, J. E. Gomes‐Filho
  International Endodontic Journal.2018; 51(8): 889.     CrossRef
• The use of Bioceramics as root-end filling materials in periradicular surgery: A literature review
  Sumaya M. Abusrewil, William McLean, J. Alun Scott
  The Saudi Dental Journal.2018; 30(4): 273.     CrossRef
• Endodontic medicine: interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials
  Luciano Tavares Angelo Cintra, Carlos Estrela, Mariane Maffei Azuma, Índia Olinta de Azevedo Queiroz, Toshihisa Kawai, João Eduardo Gomes-Filho
  Brazilian Oral Research.2018;[Epub]     CrossRef
• Comparative Evaluation of Marginal Integrity of Mineral Trioxide Aggregate and Biodentine as Retrograde Filling Materials-An In Vitro Study
  Preneet Kaur, Muskan Behl
  AMEI's Current Trends in Diagnosis & Treatment.2018; 2(2): 92.     CrossRef
• Osteogenic Response of Osteoblastic Cells to Root-End Filling Materials
  Eui Ri Na, Jong Wook Moon, Young Joon Kim
  Materials Science Forum.2018; 926: 95.     CrossRef
• Hard tissue reaction to mineral trioxide aggregate and experimental root-end filling material in guinea pig mandibles
  Ali Akhavan, Peter Parashos, Sayed Mohammad Razavi, Amin Davoudi, Elham Shadmehr
  Journal of Dental Sciences.2017; 12(2): 107.     CrossRef
• Management of extensive external apical root resorption leading to root perforation
  Robia Ghafoor, Sadia Tabassum, Muhammad Hasan Hameed
  BMJ Case Reports.2017; : bcr-2017-220234.     CrossRef
• Factors affecting the periapical healing process of endodontically treated teeth
  Roberto Holland, João Eduardo Gomes Filho, Luciano Tavares Angelo Cintra, Índia Olinta de Azevedo Queiroz, Carlos Estrela
  Journal of Applied Oral Science.2017; 25(5): 465.     CrossRef
• Tissue Reaction to Different Types of Calcium Hydroxide Paste in Rat
  Mina Zarei, Maryam Javidi, Maryam Gharechahi, Moaied Kateb, Reza Zare, Ziba Shirkhani Kelagari
  The Bulletin of Tokyo Dental College.2016; 57(2): 57.     CrossRef
• Sealing Ability of Root-end Filling Materials
  Alvaro Henrique Borges, Matheus Coelho Bandéca, Cyntia Rodrigues de Araújo Estrela, Octávio Amezcua, Álvaro Cruz Gonzalez, Carlos Estrela
  The Journal of Contemporary Dental Practice.2015; 16(3): 210.     CrossRef
• Comparative analysis of physicochemical properties of root perforation sealer materials
  Maura Cristiane Gonçales Orçati Dorileo, Fábio Luis Miranda Pedro, Matheus Coelho Bandeca, Orlando Aguirre Guedes, Ricardo Dalla Villa, Alvaro Henrique Borges
  Restorative Dentistry & Endodontics.2014; 39(3): 201.     CrossRef
• Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials
  Young-Eun Jang, Bin-Na Lee, Jeong-Tae Koh, Yeong-Joon Park, Nam-Eok Joo, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
  Restorative Dentistry & Endodontics.2014; 39(2): 89.     CrossRef
• The Era of Endodontic Research…………Root-end Filling Materials
  
  International Journal of Clinical Pediatric Dentistry.2014;[Epub]     CrossRef
• Rational design and fabrication of a β-dicalcium silicate-based multifunctional cement with potential for root canal filling treatment
  Xianyan Yang, Min Liu, Yu Zhao, Hongyu Jia, Sanzhong Xu, Xigong Li, Xiaoyi Chen, Feng Zhang, Changyou Gao, Zhongru Gou
  J. Mater. Chem. B.2014; 2(24): 3830.     CrossRef