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Saad Al-Nazhan 3 Articles
Clinical and radiographic outcomes of regenerative endodontic treatment performed by endodontic postgraduate students: a retrospective study
Hadi Rajeh Alfahadi, Saad Al-Nazhan, Fawaz Hamad Alkazman, Nassr Al-Maflehi, Nada Al-Nazhan
Restor Dent Endod 2022;47(2):e24.   Published online May 9, 2022
DOI: https://doi.org/10.5395/rde.2022.47.e24
AbstractAbstract PDFPubReaderePub
Objectives

Regenerative endodontic treatment is a clinical procedure aimed at biologically regenerating damaged root canal tissue of immature permanent teeth. This study aimed to report the outcomes of regenerative endodontic treatment performed by endodontic postgraduate students.

Materials and Methods

Clinical and radiographic data of 27 patients, aged 10–22 years, who underwent regenerative treatment of immature permanent teeth from 2015 to 2019 were followed up, wherein clinical and radiographic examinations were performed for each patient. Postoperative success rate and tooth survival were analyzed, and the postoperative radiographic root area changes were quantified.

Results

A total of 23 patients attended the dental appointments, showing that all teeth survived and were asymptomatic. Specifically, 7 periapical pathosis cases were completely healed, 12 were incompletely healed, and 4 cases failed. Moreover, significant differences were found between discolored and non-discolored teeth, and between the presence or absence of periapical radiolucency. Additionally, 3 anterior teeth showed complete closure of the apical foramen, while the apical foramen width was reduced in 17 teeth and failed in 3 teeth. Root length was also found to have been increased in 7 anterior and 4 posterior teeth, and the average length ranged from 4.00–0.63 mm in the anterior teeth, 2.85–1.48 mm of the mesial root, and 2.73–2.16 mm of the molar teeth distal root. Furthermore, calcified tissue deposition was observed in 7 teeth.

Conclusions

A favorable outcome of regenerative endodontic treatment of immature permanent teeth with necrotic pulp was achieved with a high survival rate.

Citations

Citations to this article as recorded by  
  • Allogeneic Bone Marrow Mesenchymal Stromal Cell Transplantation Induces Dentin Pulp Complex-like Formation in Immature Teeth with Pulp Necrosis and Apical Periodontitis
    Jose Francisco Gomez-Sosa, José E. Cardier, Olga Wittig, Dylana Díaz-Solano, Eloisa Lara, Kharelys Duque, Giselle Ramos-González
    Journal of Endodontics.2024; 50(4): 483.     CrossRef
  • Radiographic assessment of dental post and core placement at different educational levels in an undergraduate student clinic: a 4-year retrospective study
    Turki Alshehri, Nourhan M. Aly, Raand Altayyar, Deena Alghamdi, Shahad Alotaibi, Passent Ellakany
    F1000Research.2024; 12: 976.     CrossRef
  • Evaluation of the efficacy of injectable platelet‐rich fibrin versus platelet‐rich plasma in the regeneration of traumatized necrotic immature maxillary anterior teeth: A randomized clinical trial
    Maha Mohamed Abo‐Heikal, Jealan M. El‐Shafei, Samia A. Shouman, Nehal N. Roshdy
    Dental Traumatology.2024; 40(1): 61.     CrossRef
  • Radiographical assessment of post and core placement errors encountered by Saudi dental students at different educational levels
    Turki Alshehri, Nourhan M. Aly, Raand Altayyar, Deena Alghamdi, Shahad Alotaibi, Passent Ellakany
    F1000Research.2023; 12: 976.     CrossRef
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  • 4 Web of Science
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The prevalence of radix molaris in the mandibular first molars of a Saudi subpopulation based on cone-beam computed tomography
Hassan AL-Alawi, Saad Al-Nazhan, Nassr Al-Maflehi, Mazen A. Aldosimani, Mohammed Nabil Zahid, Ghadeer N. Shihabi
Restor Dent Endod 2020;45(1):e1.   Published online November 14, 2019
DOI: https://doi.org/10.5395/rde.2020.45.e1
AbstractAbstract PDFPubReaderePub
Objectives

The purpose of this study was to determine the incidence of radix molaris (RM) (entomolaris and paramolaris) in the mandibular first permanent molars of a sample Saudi Arabian subpopulation using cone-beam computed tomography (CBCT).

Materials and Methods

A total of 884 CBCT images of 427 male and 457 female Saudi citizens (age 16 to 70 years) were collected from the radiology department archives of 4 dental centers. A total of 450 CBCT images of 741 mature mandibular first molars that met the inclusion criteria were reviewed. The images were viewed at high resolution by 3 examiners and were analyzed with Planmeca Romexis software (version 5.2).

Results

Thirty-three (4.5%) mandibular first permanent molars had RM, mostly on the distal side. The incidence of radix entomolaris (EM) was 4.3%, while that of radix paramolaris was 0.3%. The RM roots had one canal and occurred more unilaterally. No significant difference in root configuration was found between males and females (p > 0.05). Types I and III EM root canal configurations were most common, while type B was the only RP configuration observed.

Conclusions

The incidence of RM in the mandibular first molars of this Saudi subpopulation was 4.5%. Identification of the supernumerary root can avoid missing the canal associated with the root during root canal treatment.

Citations

Citations to this article as recorded by  
  • Evaluation of the variations of mandibular molars and the distance from root apex to the inferior alveolar nerve in Saudi Sub-population: Three-dimensional radiographic evaluation
    Tariq Mohammed Aqili, Esam Sami Almuzaini, Abdulbari Saleh Aljohani, Ahmed Khaled Al Saeedi, Hassan Abdulmuti Hammudah, Muath Alassaf, Muhannad M. Hakeem, Mohmed Isaqali Karobari
    PLOS ONE.2025; 20(2): e0317053.     CrossRef
  • Assessment of the root and canal morphology in the permanent dentition of Saudi Arabian population using cone beam computed and micro-computed tomography – a systematic review
    Mohammed Mustafa, Rumesa Batul, Mohmed Isaqali Karobari, Hadi Mohammed Alamri, Abdulaziz Abdulwahed, Ahmed A. Almokhatieb, Qamar Hashem, Abdullah Alsakaker, Mohammad Khursheed Alam, Hany Mohamed Aly Ahmed
    BMC Oral Health.2024;[Epub]     CrossRef
  • Prevalence of radix accesoria dentis in a northern Peruvian population evaluated by cone-beam tomography
    Karla Renata León-Almanza, Anthony Adrián Jaramillo-Nuñez, Catherin Angélica Ruiz-Cisneros, Paul Martín Herrera-Plasencia
    Heliyon.2024; 10(16): e35919.     CrossRef
  • Radix molaris is a hidden truth of mandibular first permanent molars: A descriptive- analytic study using cone beam computed tomography
    Mohammed A. Alobaid, Saurabh Chaturvedi, Ebtihal Mobarak S. Alshahrani, Ebtsam M. Alshehri, Amal S. Shaiban, Mohamed Khaled Addas, Giuseppe Minervini
    Technology and Health Care.2023; 31(5): 1957.     CrossRef
  • Prevalence of Radix Entomolaris in Mandibular Permanent Molars Analyzed by Cone-Beam CT in the Saudi Population of Ha'il Province
    Moazzy I Almansour, Ahmed A Madfa, Adhwaa F Algharbi, Reem Almuslumani, Noeer K Alshammari, Ghufran M Al Hussain
    Cureus.2023;[Epub]     CrossRef
  • Prevalence of radix entomolaris in India and its comparison with the rest of the world
    Sumit MOHAN, Jyoti THAKUR
    Minerva Dental and Oral Science.2022;[Epub]     CrossRef
  • Radix Paramolaris an Endodontic Challenge: A Case Report
    Ashwini B Prasad, Deepak Raisingani, Ridhima Gupta, Rimjhim Jain
    Journal of Mahatma Gandhi University of Medical Sciences and Technology.2022; 7(1): 32.     CrossRef
  • Evaluation of Radix Entomolaris and Middle Mesial Canal in Mandibular Permanent First Molars in an Iraqi Subpopulation Using Cone‐Beam Computed Tomography
    Ranjdar Mahmood Talabani, Kazhan Omer Abdalrahman, Rawa Jamal Abdul, Dlsoz Omer Babarasul, Sara Hilmi Kazzaz, Heng Bo Jiang
    BioMed Research International.2022;[Epub]     CrossRef
  • Evaluation of Root Canal Configuration of Maxillary and Mandibular First Molar by CBCT: A Retrospective Cross-Sectional Study
    Rakan Rafdan Alhujhuj, Rizwan Jouhar, Muhammad Adeel Ahmed, Abdullatif Abdulrahman Almujhim, Mohammed Tariq Albutayh, Necdet Adanir
    Diagnostics.2022; 12(9): 2121.     CrossRef
  • Ethnical Anatomical Differences in Mandibular First Permanent Molars between Indian and Saudi Arabian Subpopulations: A Retrospective Cross-sectional Study
    Abdulwahab Alamir, Mohammed Mashyakhy, Apathsakayan Renugalakshmi, Thilla S Vinothkumar, Anandhi S Arthisri, Ahmed Juraybi
    The Journal of Contemporary Dental Practice.2021; 22(5): 484.     CrossRef
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Microorganism penetration in dentinal tubules of instrumented and retreated root canal walls. In vitro SEM study
Saad Al-Nazhan, Alaa Al-Sulaiman, Fellwa Al-Rasheed, Fatimah Alnajjar, Bander Al-Abdulwahab, Abdulhakeem Al-Badah
Restor Dent Endod 2014;39(4):258-264.   Published online July 22, 2014
DOI: https://doi.org/10.5395/rde.2014.39.4.258
AbstractAbstract PDFPubReaderePub
Objectives

This in vitro study aimed to investigate the ability of Candida albicans (C. albicans) and Enterococcus faecalis (E. faecalis) to penetrate dentinal tubules of instrumented and retreated root canal surface of split human teeth.

Materials and Methods

Sixty intact extracted human single-rooted teeth were divided into 4 groups, negative control, positive control without canal instrumentation, instrumented, and retreated. Root canals in the instrumented group were enlarged with endodontic instruments, while root canals in the retreated group were enlarged, filled, and then removed the canal filling materials. The teeth were split longitudinally after canal preparation in 3 groups except the negative control group. The teeth were inoculated with both microorganisms separately and in combination. Teeth specimens were examined by scanning electron microscopy (SEM), and the depth of penetration into the dentinal tubules was assessed using the SMILE view software (JEOL Ltd).

Results

Penetration of C. albicans and E. faecalis into the dentinal tubules was observed in all 3 groups, although penetration was partially restricted by dentin debris of tubules in the instrumented group and remnants of canal filling materials in the retreated group. In all 3 groups, E. faecalis penetrated deeper into the dentinal tubules by way of cell division than C. albicans which built colonies and penetrated by means of hyphae.

Conclusions

Microorganisms can easily penetrate dentinal tubules of root canals with different appearance based on the microorganism size and status of dentinal tubules.

Citations

Citations to this article as recorded by  
  • Influence of photobiomodulation therapy on regenerative potential of non-vital mature permanent teeth in healthy canine dogs
    S. F. Khattab, Y. F. Gomaa, E. A. E. Abdelaziz, N. M. A. Khattab
    European Archives of Paediatric Dentistry.2025;[Epub]     CrossRef
  • A 12-month randomized controlled trial to assess the efficacy of revitalization of retreated mature incisors with periapical radiolucency in adolescents
    Ahmad Abdel Hamid Elheeny, Osama Seif-Elnasr Hussien, Mahmoud Ahmed Abdelmotelb, Yassmin Mohamed ElMakawi, Norhan Khaled Omar Wahba
    Scientific Reports.2024;[Epub]     CrossRef
  • Failed Regenerative Endodontic Case Treated by Modified Aspiration-irrigation Technique and Apexification
    Loai Alsofi, Sara Almarzouki
    The Journal of Contemporary Dental Practice.2024; 25(1): 92.     CrossRef
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    Rishabh Patel, Gaurav Shinde, Prashant Bondarde, Aruna Vishwakarma, Madhuri Bhandare, Vaibhavi Pharne
    Journal of Indian Society of Pedodontics and Preventive Dentistry.2024; 42(3): 195.     CrossRef
  • Influence of root canal moisture on the penetration of TotalFill bioceramic sealer into the dentinal tubules: A confocal laser scanning microscopy study
    Archika M Singh, Tarek M Elsewify, Walid S El-Sayed, Husam H Nuawafleh, Ranya F Elemam, Bassem M Eid
    Saudi Endodontic Journal.2024; 14(2): 187.     CrossRef
  • Fungi and bacteria occupy distinct spatial niches within carious dentin
    Rosalyn M. Sulyanto, Clifford J. Beall, Kasey Ha, Joseph Montesano, Jason Juang, John R. Dickson, Shahr B. Hashmi, Seth Bradbury, Eugene J. Leys, Mira Edgerton, Sunita P. Ho, Ann L. Griffen, Alex Andrianopoulos
    PLOS Pathogens.2024; 20(5): e1011865.     CrossRef
  • The advancement in irrigation solution within the field of endodontics, A Review
    Fatima Fahad , Raghad A Al-Hashimi , Munther J Hussain
    Journal of Baghdad College of Dentistry.2024; 36(1): 54.     CrossRef
  • Supplementary methods for filling material removal: A systematic review and meta-analysis of micro-CT imaging studies
    Bruna Venzke Fischer, Taynara Santos Goulart, Filipe Colombo Vitali, Diego Leonardo de Souza, Cleonice da Silveira Teixeira, Lucas da Fonseca Roberti Garcia
    Journal of Dentistry.2024; 151: 105445.     CrossRef
  • Impact of calcium hydroxide and 2-hydroxyisocaproic acid on the microhardness of root dentine: an in vitro study
    Nandini T. Niranjan, Protim Ghosh Dastidar, Raghavendra Penukonda, Galvin Sim Siang Lin, Roopa Babannavar, Arun Jaysheel, Harshada Pattar
    Odontology.2024; 112(3): 711.     CrossRef
  • Fabrication of Rapidly Soluble Zn2+-Releasing Phosphate-Based Glass and Its Incorporation into Dental Resin
    Fan Deng, Haruaki Kitagawa, Tomoki Kohno, Tingyi Wu, Naoya Funayama, Pasiree Thongthai, Hefei Li, Gabriela L. Abe, Ranna Kitagawa, Jun-Ichi Sasaki, Satoshi Imazato
    Molecules.2024; 29(21): 5098.     CrossRef
  • Combined effect of electrical energy and graphene oxide on Enterococcus faecalis biofilms
    Myung-Jin LEE, Mi-Ah KIM, Kyung-San MIN
    Dental Materials Journal.2023; 42(6): 844.     CrossRef
  • Effect of Different Irrigant Activation Techniques on the Penetration of Calcium Hydroxide, an Intracanal Medicament: An In Vitro Study
    Radha Kalyani Narla, Ravi kumar J, Tejosmita Chowdary Pavuluri, Krishna Chaitanya P, Ramesh Penumaka, Ratna Kamal Nagelli
    Cureus.2023;[Epub]     CrossRef
  • Comparative assessment of antibacterial effect of two types of laser and their effect on morphology and mineral content of dentin
    Soha Adel Abdou, Haythem S Moharrum, Elsayed Abdallah Eltayeb
    Journal of The Arab Society for Medical Research.2023; 18(2): 117.     CrossRef
  • Efficacy of Endodontic Disinfection Protocols in an E. faecalis Biofilm Model—Using DAPI Staining and SEM
    Maria Dede, Sabine Basche, Jörg Neunzehn, Martin Dannemann, Christian Hannig, Marie-Theres Kühne
    Journal of Functional Biomaterials.2023; 14(4): 176.     CrossRef
  • Antibacterial Effect of Matricaria chamomilla L. Extract Against Enterococcus faecalis
    Ariana Kameri, Arben Haziri, Zeqir Hashani, Agime Dragidella, Kemajl Kurteshi, Arsim Kurti
    Clinical, Cosmetic and Investigational Dentistry.2023; Volume 15: 13.     CrossRef
  • Efficacy of Smear Layer Removal at the Apical One-Third of the Root Using Different Protocols of Erbium-Doped Yttrium Aluminium Garnet (Er:YAG) Laser
    Amel Yousif Habshi, Nausheen Aga, Khadija Yousif Habshi, Muna Eisa Mohamed Hassan, Ziaullah Choudhry, Muhammad Adeel Ahmed, Azeem Ul Yaqin Syed, Rizwan Jouhar
    Medicina.2023; 59(3): 433.     CrossRef
  • Minimally invasive management of vital teeth requiring root canal therapy
    E. Karatas, M. Hadis, W. M. Palin, M. R. Milward, S. A. Kuehne, J. Camilleri
    Scientific Reports.2023;[Epub]     CrossRef
  • Functionalized surface of PLGA nanoparticles in thermosensitive gel to enhance the efficacy of antibiotics against antibiotic resistant infections in endodontics: A randomized clinical trial
    Mona G. Arafa, Hadeel A. Mousa, Mohamed Medhat Kataia, Shehabeldin M., Nagia N. Afifi
    International Journal of Pharmaceutics: X.2023; 6: 100219.     CrossRef
  • Critical analysis of research methods and experimental models to study removal of root filling materials
    Mahdi A. Ajina, Pratik K. Shah, Bun San Chong
    International Endodontic Journal.2022; 55(S1): 119.     CrossRef
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    BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY.2022; : 15.     CrossRef
  • Antimicrobial action of photodynamic therapy on Enterococcus faecalis biofilm using curing light, curcumin and riboflavin
    Mahsa Moradi, Mahta Fazlyab, Maryam Pourhajibagher, Nasim Chiniforush
    Australian Endodontic Journal.2022; 48(2): 274.     CrossRef
  • Candida albicans and Enterococcus faecalis biofilm frenemies: When the relationship sours
    Om Alkhir Alshanta, Khawlah Albashaireh, Emily McKloud, Christopher Delaney, Ryan Kean, William McLean, Gordon Ramage
    Biofilm.2022; 4: 100072.     CrossRef
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    Odontology.2021; 109(3): 687.     CrossRef
  • Dentin Disinfection Efficacy Using Four Different Irrigation Protocols
    David Jaramillo, Jose L Ibarrola, Ana Arias, Phillipe Sleiman, Ali Naji, David E Jaramillo
    Dental Research and Management.2021; : 33.     CrossRef
  • Histologic, Radiographic, and Micro-Computed Tomography Evaluation of Experimentally Enlarged Root Apices in Dog Teeth with Apical Periodontitis after Regenerative Treatment
    Mohammed S. Alenazy, Saad Al-Nazhan, Hezekiah A Mosadomi
    Current Therapeutic Research.2021; 94: 100620.     CrossRef
  • Comparative evaluation of dentin volume removal and centralization of the root canal after shaping with the ProTaper Universal, ProTaper Gold, and One-Curve instruments using micro-CT
    Hatice Yalniz, Mehrdad Koohnavard, Aysenur Oncu, Berkan Celikten, Ayse Isil Orhan, Kaan Orhan
    Journal of Dental Research, Dental Clinics, Dental Prospects.2021; 15(1): 47.     CrossRef
  • The influence of centrifugation and inoculation time on the number, distribution, and viability of intratubular bacteria and surface biofilm in deciduous and permanent bovine dentin
    Viktoria A. Dezhurko-Korol, Nina E. Novozhilova, Irina M. Makeeva, Anastasia Yu. Arkhipova, Mihail M. Moisenovich, Ludmila V. Akhmadishina, Alexander N. Lukashev, Alexander M. Semenov, Maria R. Leontieva, Svetlana F. Byakova
    Archives of Oral Biology.2020; 114: 104716.     CrossRef
  • Antimicrobial efficacy of synthetic and natural-derived novel endodontic irrigating solution – An In vitro study
    Thangi Sowjanya, Sudhakar Naidu, MahendraVarma Nadimpalli, GowtamDev Dondapati, TB V G Raju, ParvathaneniKrishna Prasad
    Journal of the International Clinical Dental Research Organization.2020; 12(1): 21.     CrossRef
  • Comparative Evaluation of Antimicrobial Efficacy of Three Different Intracanal Medicaments against Candida albicans: An In Vitro Study
    Ravi Vaiyapuri, Jambai S Sivakumar, Chittrarasu Mathimaraiselvan, Andamuthu Sivakumar, Anjaneya Shiva Prasad, Sasmitha Chandrasekaran
    Journal of Operative Dentistry & Endodontics.2020; 5(2): 79.     CrossRef
  • Assessment of Nitrofurantoin as an Experimental Intracanal Medicament in Endodontics
    Mewan Salahalddin A. Alrahman, Bestoon Muhammed Faraj, Kawa F. Dizaye, Abdelwahab Omri
    BioMed Research International.2020;[Epub]     CrossRef
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    Journal of Drug Delivery Science and Technology.2019; 51: 499.     CrossRef
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    International Journal of Pharmaceutics.2018; 552(1-2): 206.     CrossRef
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    Xiaoqiang Sun, Shujing Wang, Yue Yang, Chunxiong Luo, Benxiang Hou
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    Restorative Dentistry & Endodontics.2015; 40(2): 149.     CrossRef
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