Genetic information such as DNA sequences has been limited to fully explain mechanisms of gene regulation and disease process. Epigenetic mechanisms, which include DNA methylation, histone modification and non-coding RNAs, can regulate gene expression and affect progression of disease. Although studies focused on epigenetics are being actively investigated in the field of medicine and biology, epigenetics in dental research is at the early stages. However, studies on epigenetics in dentistry deserve attention because epigenetic mechanisms play important roles in gene expression during tooth development and may affect oral diseases. In addition, understanding of epigenetic alteration is important for developing new therapeutic methods. This review article aims to outline the general features of epigenetic mechanisms and describe its future implications in the field of dentistry.

Citations

Citations to this article as recorded by  

• Effect of Long Non-coding RNA and DNA Methylation on Gene Expression in Dental Fluorosis
  Xiaoyan Hu, Huiru Li, Minzhi Yang, Yujiong Chen, Ailin Zeng, Jiayuan Wu, Jian Zhang, Yuan Tian, Jing Tang, Shengyan Qian, Mingsong Wu
  Biological Trace Element Research.2024; 202(1): 221.     CrossRef
• MicroRNAs: Mighty Mite RNAs in Oral Diseases
  Devapriya Appukuttan, P. S. G. Prakash
  Journal of Interdisciplinary Dentistry.2024; 14(3): 145.     CrossRef
• Role of epigenetics in OSCC: an understanding above genetics
  Priyanka P. Vatsa, Yogita Jindal, Janhavi Bhadwalkar, Ambika Chamoli, Vinal Upadhyay, Amit Mandoli
  Medical Oncology.2023;[Epub]     CrossRef
• Downregulation of miRNA‐26 in chronic periodontitis interferes with innate immune responses and cell migration by targeting phospholipase C beta 1
  Juhi R. Uttamani, Afsar R. Naqvi, Araceli Maria Valverde Estepa, Varun Kulkarni, Maria F. Brambila, Gloria Martínez, Gabriela Chapa, Christine D. Wu, Wei Li, Sona Rivas‐Tumanyan, Salvador Nares
  Journal of Clinical Periodontology.2023; 50(1): 102.     CrossRef
• The Potential Role of Epigenetic Modifications on Different Facets in the Periodontal Pathogenesis
  Samuel Laberge, Daniel Akoum, Piotr Wlodarczyk, Jean-Daniel Massé, Dominique Fournier, Abdelhabib Semlali
  Genes.2023; 14(6): 1202.     CrossRef
• The Role of Histone Acetylation Modification in Dental Tissue-Derived Mesenchymal Stem Cells and Odontogenesis
  Haoling Chen, Zijing Huang, Chuxiao Chen
  Cellular Reprogramming.2023; 25(1): 11.     CrossRef
• Your health is in your mouth: A comprehensive view to promote general wellness
  Antonia Barranca-Enríquez, Tania Romo-González
  Frontiers in Oral Health.2022;[Epub]     CrossRef
• A Brief Landscape of Epigenetic Mechanisms in Dental Pathologies
  Wojciech Tynior, Joanna Katarzyna Strzelczyk
  Cytology and Genetics.2022; 56(5): 475.     CrossRef
• Influence of epigenetics on periodontitis and peri‐implantitis pathogenesis
  Lena Larsson, Nolan M. Kavanagh, Trang V. N. Nguyen, Rogerio M. Castilho, Tord Berglundh, William V. Giannobile
  Periodontology 2000.2022; 90(1): 125.     CrossRef
• DNA methylation alterations and their potential influence on macrophage in periodontitis
  Yiyang Jiang, Jingfei Fu, Juan Du, Zhenhua Luo, Lijia Guo, Junji Xu, Yi Liu
  Oral Diseases.2022; 28(2): 249.     CrossRef
• Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells
  Qin Li, Rui-Fang Yan, Yong-Xiao Yang, Chun-liu Mi, Yan-long Jia, Tian-Yun Wang
  Frontiers in Bioengineering and Biotechnology.2022;[Epub]     CrossRef
• Synthesis and Anticancer Potential of New Hydroxamic Acid Derivatives as Chemotherapeutic Agents
  Işıl Nihan Korkmaz, Hasan Özdemir
  Applied Biochemistry and Biotechnology.2022; 194(12): 6349.     CrossRef
• Impact of Epigenetic Alterations in the Development of Oral Diseases
  Rodopi Emfietzoglou, Evangelos Pachymanolis, Christina Piperi
  Current Medicinal Chemistry.2021; 28(6): 1091.     CrossRef
• Basics of Epigenetics and Role of Epigenetics in Diabetic Complications
  Andamuthu Yamunadevi, Ramani Pratibha, Muthusamy Rajmohan, Sengottaiyan Mahendraperumal, Nalliappan Ganapathy
  Journal of Pharmacy and Bioallied Sciences.2021; 13(Suppl 1): S336.     CrossRef
• Effects of Epigenetic Regulation on Cancer
  Muhammet Mesut Nezir ENGİN, Esra ÖZEN ENGİN, Recep ERÖZ, Gorkem DULGER, Hüseyin YÜCE
  Journal of Biotechnology and Strategic Health Research.2021; 5(1): 1.     CrossRef
• Photobiomodulation therapy improves human dental pulp stem cell viability and migration in vitro associated to upregulation of histone acetylation
  Ivana M. Zaccara, Letícia B. Mestieri, Emily F. S. Pilar, Maria S. Moreira, Fabiana S. Grecca, Manoela D. Martins, Patrícia Maria Poli Kopper
  Lasers in Medical Science.2020; 35(3): 741.     CrossRef
• The Biology of Social Adversity Applied to Oral Health
  N. Gomaa, H. Tenenbaum, M. Glogauer, C. Quiñonez
  Journal of Dental Research.2019; 98(13): 1442.     CrossRef
• The effect of DNA methylation on the miRNA expression pattern in lipopolysaccharide-induced inflammatory responses in human dental pulp cells
  Zehuan Mo, Qimeng Li, Luhui Cai, Minkang Zhan, Qiong Xu
  Molecular Immunology.2019; 111: 11.     CrossRef
• One-Carbon Metabolism Links Nutrition Intake to Embryonic Development via Epigenetic Mechanisms
  Si Wu, Jun Zhang, Feifei Li, Wei Du, Xin Zhou, Mian Wan, Yi Fan, Xin Xu, Xuedong Zhou, Liwei Zheng, Yachuan Zhou
  Stem Cells International.2019; 2019: 1.     CrossRef
• Epigenetic regulation in dental pulp inflammation
  T Hui, C Wang, D Chen, L Zheng, D Huang, L Ye
  Oral Diseases.2017; 23(1): 22.     CrossRef
• Current Concepts of Epigenetics and Its Role in Periodontitis
  Lena Larsson
  Current Oral Health Reports.2017; 4(4): 286.     CrossRef
• The periodontal war: microbes and immunity
  Jeffrey L. Ebersole, Dolph Dawson, Pinar Emecen‐Huja, Radhakrishnan Nagarajan, Katherine Howard, Martha E. Grady, Katherine Thompson, Rebecca Peyyala, Ahmad Al‐Attar, Kathryn Lethbridge, Sreenatha Kirakodu, Octavio A. Gonzalez
  Periodontology 2000.2017; 75(1): 52.     CrossRef
• Epigenetic regulatory elements: Recent advances in understanding their mode of action and use for recombinant protein production in mammalian cells
  Niamh Harraghy, David Calabrese, Igor Fisch, Pierre‐Alain Girod, Valérie LeFourn, Alexandre Regamey, Nicolas Mermod
  Biotechnology Journal.2015; 10(7): 967.     CrossRef
• Protocol for assessing maternal, environmental and epigenetic risk factors for dental caries in children
  Surani Fernando, David J. Speicher, Mahmoud M. Bakr, Miles C. Benton, Rodney A. Lea, Paul A. Scuffham, Gabor Mihala, Newell W. Johnson
  BMC Oral Health.2015;[Epub]     CrossRef

Citations

Citations to this article as recorded by  

• Shear bond strength of metallic orthodontic brackets to zirconium crowns treated by sandblasting compared to enamel using a universal adhesive: An in vitro study
  Fatemeh Namvar, Mansoure Zarmehi Shahrebabak, Sepideh Arab, Maryam Abdoh Tabrizi, Amir Ghasemi, Fatemeh Safari
  International Orthodontics.2022; 20(2): 100640.     CrossRef
• The effect of fusion sputtering surface treatment on microshear bond strength of zirconia and MDP-containing resin cement
  Nesma Ali, Ahmed Safwat, Moustafa Aboushelib
  Dental Materials.2019; 35(6): e107.     CrossRef
• Effects of air-abrasion pressure on the resin bond strength to zirconia: a combined cyclic loading and thermocycling aging study
  Eman Z. Al-Shehri, Afnan O. Al-Zain, Alaa H. Sabrah, Sarah S. Al-Angari, Laila Al Dehailan, George J. Eckert, Mutlu Özcan, Jeffrey A. Platt, Marco C. Bottino
  Restorative Dentistry & Endodontics.2017; 42(3): 206.     CrossRef
• Shear Bond Strength of MDP-Containing Self-Adhesive Resin Cement and Y-TZP Ceramics: Effect of Phosphate Monomer-Containing Primers
  Jin-Soo Ahn, Young-Ah Yi, Yoon Lee, Deog-Gyu Seo
  BioMed Research International.2015; 2015: 1.     CrossRef
• Preliminary studies on the effects of in situ synthesized polycrystalline particulates on the bonding strength of resin to zirconia ceramic surface
  Yueming Tian, Lingling Zhang, Zutai Zhang, Ning Ding, Yan Liu, Guozhong Tian
  Applied Surface Science.2015; 357: 961.     CrossRef

While it is reasonably well known that certain dental procedures increase the temperature of the tooth's surface, of greater interest is their potential damaging effect on the pulp and tooth-supporting tissues. Previous studies have investigated the responses of the pulp, periodontal ligament, and alveolar bone to thermal irritation and the temperature at which thermal damage is initiated. There are also many in vitro studies that have measured the temperature increase of the pulp and tooth-supporting tissues during restorative and endodontic procedures. This review article provides an overview of studies measuring temperature increases in tooth structures during several restorative and endodontic procedures, and proposes clinical guidelines for reducing potential thermal hazards to the pulp and supporting tissues.

Citations

Citations to this article as recorded by  

• External Root Temperature and Its Relationship With Dentin Thickness During Gutta-Percha Removal Procedures With Ultrasound. An Ex Vivo Study
  Juan Ramon Salazar-Silva, Carlos Emilio Paschoal, Daniela de Fatima Teixeira da Silva, Denise Maria Zezell, Fábio Luiz Cunha D'Assuncao, Celso Luiz Caldeira
  Journal of Endodontics.2025; 51(3): 340.     CrossRef
• Temperature Changes of NaOCl after Irrigation Using Passive Ultrasonic Irrigation, Easy Clean, and XP-Endo Finisher: A Randomized Crossover Clinical Trial
  Geraldo Edson Freitas Athayde de Moraes, Daniel Guimarães Pedro Rocha, Carlos Eduardo Fontana, Rina Andréa Pelegrine, Alexandre Sigrist de Martin, Índia Olinta De Azevedo Queiroz, Carlos Eduardo da Silveira Bueno
  European Journal of Dentistry.2025;[Epub]     CrossRef
• Comparative evaluation of increase in temperature on the external root surface of teeth during retrieval of broken NiTi instrument using two ultrasonic tips and two power settings: An in vitro study
  Ashish K. Jain, Rishabhkumar Jain, Rahul Rao, Prajakta Rao, Pooja Yadav, Vinayak Thorat
  Journal of Conservative Dentistry and Endodontics.2024; 27(6): 634.     CrossRef
• Dental health concerns for patients suffering from facial, peri-oral burns, and inhalation injury: A persistent yet underappreciated challenge
  Hans-Oliver Rennekampff, Isabelle Rennekampff, Mayer Tenenhaus
  Burns.2024; 50(9): 107224.     CrossRef
• Recent advances in the pathogenesis and prevention strategies of dental calculus
  Yu Wei, Gao-peng Dang, Zhao-yang Ren, Mei-chen Wan, Chen-yu Wang, Hong-bo Li, Tong Zhang, Franklin R. Tay, Li-na Niu
  npj Biofilms and Microbiomes.2024;[Epub]     CrossRef
• In Vitro Evaluation of Root Surface Temperature Using Different Endodontic Filling Techniques
  Lea Külzer, Theresia Saban, Andreas Braun, Johannes-S. Wenzler
  Applied Sciences.2024; 14(21): 9830.     CrossRef
• Accuracy comparison of single- and double-sleeve endodontic guides for fiber post removal
  Omid Dianat, Mandana Naseri, Yaser Safi, Ali Modaberi, Nazanin Zargar, Ove A. Peters, Mehran Farajollahi
  BMC Oral Health.2024;[Epub]     CrossRef
• The Effect of Water Coolant and Bur Type on Pulp Temperature When Removing Tooth Structure and Restorative Dental Materials
  C Mafrici, M Kingston, R Grice, PV Abbott
  Operative Dentistry.2024; 49(1): 91.     CrossRef
• A Comparative Study of Temperature Variations in Incisor Root Surfaces During Root Canal Preparation Using Various Rotary Systems and Irrigation Protocols
  Mihai Paven, Adrian-George Marinescu, Osama Abuabboud, Laura-Elena Cirligeriu, Luminita Maria Nica, Vlad Tiberiu Alexa, Ruxandra Sava Rosianu, Atena Galuscan, Roxana Oancea
  Journal of Clinical Medicine.2024; 13(23): 7484.     CrossRef
• The Effect of Restoration Polymerization and Residual Dentine Thickness on Thermal Changes of Pulp Chamber of Immature Permanent Teeth
  Kevser Kolçakoğlu, Merve Aksoy, Cenkhan Bal, Akif Demirel, Firdevs Tulga Öz
  Pesquisa Brasileira em Odontopediatria e Clínica Integrada.2024;[Epub]     CrossRef
• Efficacy of pulpotomy in managing irreversible pulpitis in mature permanent teeth: A systematic review and meta-analysis
  Yuanyuan Li, Wenying Wang, Qian Zeng, Michelle Tang, Joshua Massey, Brian E. Bergeron, Lisha Gu, Franklin R. Tay
  Journal of Dentistry.2024; 144: 104923.     CrossRef
• Evaluation of diamond rotary instruments marketed for removing zirconia restorations
  Severin Hunziker, Lea Thorpe, Nicola U. Zitzmann, Nadja Rohr
  The Journal of Prosthetic Dentistry.2024; 131(5): 895.     CrossRef
• Influence of different cutting instruments and rotational speeds on heat generation and cutting efficiency when sectioning different types of zirconia
  Lisa Türp, Frank Lehmann, Sebastian Wille, Matthias Kern
  Journal of the Mechanical Behavior of Biomedical Materials.2024; 160: 106715.     CrossRef
• Loss of pulp vitality correlated with the duration of the interim restoration and the experience of the dentist: A retrospective study
  Göran Nilsson, Stefan Ellner, Liselott Arnebrant, Lars Brudin, Christel Larsson
  The Journal of Prosthetic Dentistry.2023; 130(6): 833.     CrossRef
• Thermal Sensing of Photo-Activated Dental Resin Composites Using Infrared Thermography
  Turki A. Bakhsh, Abdulaziz Alfaifi, Yousef Alghamdi, Mohannad Nassar, Roaa A. Abuljadyel
  Polymers.2023; 15(20): 4117.     CrossRef
• Effect of irrigation acid solutions on cleaning and bond strength to post‐space dentin
  C. de Melo Alencar, J. Ferrari Zaniboni, J. Felipe Besegato, A. Patricia Oliveira Barros, M. Bena Gélio, L Garcia Belizário, E. Maximiliano Fernandez Godoy, M. Carlos Kuga
  European Journal of Oral Sciences.2023;[Epub]     CrossRef
• Effect of Intermediate Irrigation on Temperature Rise during Broken NiTi File Removal Using Ultrasonic Device
  László Pintér, Károly Krajczár, Fanni Őry, József Szalma, Edina Lempel
  Applied Sciences.2023; 13(17): 9761.     CrossRef
• Top tips for improving crown preparations
  James Baker, Ewen McColl, Christopher Tredwin
  British Dental Journal.2023; 234(1): 16.     CrossRef
• Evaluation of knowledge and awareness of pediatric oral health among school teachers of Hazaribag before and after oral health education.
  Vipin Ahuja, Annapurna Ahuja, Nilima Thosar
  F1000Research.2023; 12: 1292.     CrossRef
• Applications of single laser pulse from Nd:doped lasers for cleaning of small diameter carious lesions. Modelling and analytical study
  T Uzunov, M Deneva, P Uzunova, M Nenchev
  Journal of Physics: Conference Series.2023; 2487(1): 012022.     CrossRef
• Accuracy of a 3D printed sleeveless guide system used for fiber post removal: An in vitro study
  Siyi Mo, Yongwei Xu, Lei Zhang, Ye Cao, Yongsheng Zhou, Xiaoxiang Xu
  Journal of Dentistry.2023; 128: 104367.     CrossRef
• Heat generated during dental treatments affecting intrapulpal temperature: a review
  Xin Er Lau, Xiaoyun Liu, Helene Chua, Wendy Jingwen Wang, Maykon Dias, Joanne Jung Eun Choi
  Clinical Oral Investigations.2023; 27(5): 2277.     CrossRef
• Pulp chamber temperature rise in light-cure bonding of brackets with and without primer, in intact versus restored teeth
  Gabriela Cenci SCHMITZ, Fernanda de Souza HENKIN, Mauricio MEZOMO, Mariana MARQUEZAN, Gabriela BONACINA, Maximiliano Schünke GOMES, Eduardo Martinelli Santayana de LIMA
  Dental Press Journal of Orthodontics.2023;[Epub]     CrossRef
• Temperature Rise in Curing Modes of Two Different Dental Light-Curing Units: The Importance of Heating Rate
  Ahmad Soori, Faezeh Soori, Farshad Kowsary, Shahin Kasraei
  International Journal of Thermophysics.2023;[Epub]     CrossRef
• Effective application of suitable single pulse of Nd:doped lasers for cleaning of initial carious lesions of human teeth. Experimental study
  T Uzunov, M Deneva, V Kazakov, P Uzunova, N Kaimakanova, M Nenchev
  Journal of Physics: Conference Series.2023; 2487(1): 012021.     CrossRef
• Comparative Evaluation of Intrapulpal Thermal Changes during the Polymerization of Different Adhesive Resin Materials: An In Vitro Study
  Pavithra K Ramanna, Suneel V Vadavadagi, Konsam Bidya Devi, Pawankumar Kamalapurkar, Shreeshail Indi, Vineetha Chakravarthy Srinivas
  The Journal of Contemporary Dental Practice.2022; 23(5): 539.     CrossRef
• Anesthetic-, irrigation- and pain-free dentistry? The case for a femtosecond laser enabled intraoral robotic device
  Ludovic Rapp, Steve Madden, Andrei V. Rode, Laurence J. Walsh, Heiko Spallek, Quan Nguyen, Van Dau, Peter Woodfield, Dzung Dao, Omar Zuaiter, Alaa Habeb, Timothy R. Hirst
  Frontiers in Dental Medicine.2022;[Epub]     CrossRef
• 4D Printing of Shape‐Memory Semi‐Interpenetrating Polymer Networks Based On Aromatic Heterochain Polymers
  Kseniia N. Bardakova, Bato Ch. Kholkhoev, Ivan A. Farion, Evgenii O. Epifanov, Olga S. Korkunova, Yuri M. Efremov, Nikita V. Minaev, Anna B. Solovieva, Peter S. Timashev, Vitaliy F. Burdukovskii
  Advanced Materials Technologies.2022;[Epub]     CrossRef
• How does indirect air-cooling influence pulp chamber temperature in different volume teeth and absence/presence of resin-based composite during light curing?
  Mathieu Mouhat, Lina Stangvaltaite-Mouhat, Emil Finnäs, Amani Andersen, Anneli Lirhus Evertsen, Bo W. Nilsen
  BMC Oral Health.2022;[Epub]     CrossRef
• Intrapulpal temperature changes during the cementation of ceramic veneers
  Edina Lempel, Dóra Kincses, Donát Szebeni, Dóra Jordáki, Bálint Viktor Lovász, József Szalma
  Scientific Reports.2022;[Epub]     CrossRef
• Femtosecond laser dentistry for precise and efficient cavity preparation in teeth
  Ludovic Rapp, Steve Madden, Julia Brand, Laurence J. Walsh, Heiko Spallek, Omar Zuaiter, Alaa Habeb, Timothy R. Hirst, Andrei V. Rode
  Biomedical Optics Express.2022; 13(9): 4559.     CrossRef
• Three Dimensional mapping of the root apex: distances between apexes and anatomical structures and external cortical plates
  Carlos Henrique FERRARI, Amjad ABU HASNA, Frederico Canato MARTINHO
  Brazilian Oral Research.2021;[Epub]     CrossRef
• Effects of 9,300 nm Carbon Dioxide Laser on Dental Hard Tissue: A Concise Review
  Vicky Wenqing Xue, Irene Shuping Zhao, Iris Xiaoxue Yin, John Yun Niu, Edward Chin Man Lo, Chun Hung Chu
  Clinical, Cosmetic and Investigational Dentistry.2021; Volume 13: 155.     CrossRef
• PHOTOPOLYMERIZED COMPOSITIONS AND LIGHT SOURCES FOR DENTAL PRACTICE (REVIEW)
  A. M. Lalatovich, M. A. Vaniev, N. V. Sidorenko, Y. A. Makedonova, D. Yu. Dyachenko, S. V. Dyachenko
  IZVESTIA VOLGOGRAD STATE TECHNICAL UNIVERSITY.2021; (12(259)): 7.     CrossRef
• Spray mist reduction by means of a high-volume evacuation system—Results of an experimental study
  Martin Koch, Christian Graetz, Essam Al-Moraissi
  PLOS ONE.2021; 16(9): e0257137.     CrossRef
• Pulp chamber temperature changes during orthodontic bonding – an in vitro study
  Aysegul Ayhan Bani, Burcu Balos Tuncer, Cumhur Tuncer
  Australasian Orthodontic Journal.2021; 37(2): 157.     CrossRef
• Thermal Behavior of Teeth During Restoration Procedure With Composite: Experimental Tests and Numerical Simulation
  M. Potenza, P. Coppa, L. Cerroni, G. Bovesecchi
  Journal of Heat Transfer.2021;[Epub]     CrossRef
• Comparative Evaluation of Thermal Alterations on External Root Surface during Mechanical Instrumentation and Thermoplasticized Gutta-percha Obturation: An Ex Vivo Study
  Rohit Sharma, Atul Jain, Madhurima Sharma, Shivani Chauhan, Abhinay Agarwal
  World Journal of Dentistry.2021; 12(5): 367.     CrossRef
• Degree of conversion and in vitro temperature rise of pulp chamber during polymerization of flowable and sculptable conventional, bulk-fill and short-fibre reinforced resin composites
  Edina Lempel, Zsuzsanna Őri, Dóra Kincses, Bálint Viktor Lovász, Sándor Kunsági-Máté, József Szalma
  Dental Materials.2021; 37(6): 983.     CrossRef
• Pulp chamber temperature changes during orthodontic bonding – an in vitro study
  Aysegul Ayhan Bani, Burcu Balos Tuncer, Cumhur Tuncer
  Australasian Orthodontic Journal.2021; 37(2): 157.     CrossRef
• Shot peening increases resistance to cyclic fatigue fracture of endodontic files
  Javier Nino-Barrera, Jose Sanchez-Aleman, Manuel Acosta-Humanez, Luis Gamboa-Martinez, Carlos Cortes-Rodriguez
  Scientific Reports.2021;[Epub]     CrossRef
• Temperature Dependence of Specific Heat of Human Enamel and Dentin: An Experimental Study
  Ahmad Soori, Farshad Kowsary, Shahin Kasraei
  International Journal of Thermophysics.2021;[Epub]     CrossRef
• Prosthodontic Applications of Polymethyl Methacrylate (PMMA): An Update
  Muhammad Sohail Zafar
  Polymers.2020; 12(10): 2299.     CrossRef
• The effect of halogen bulb and light-emitting diode light curing units on temperature increase and fibroblast viability
  Georgia Memari Trava, Juliane Almeida Santos, Lucas Paula Ramos, Pamela Beatriz Rosário Estevam dos Santos, Amjad Abu Hasna, Karen Cristina Yui, Adriano Bressane, Luciane Dias de Oliveira, Marianne Spalding
  F1000Research.2020; 9: 1369.     CrossRef
• A Study on Temperature Changes during Bone Scaling and Cutting of Dental Ultrasonic Scaling/Surgery System
  Min-Woo Sa, Tae-Jo Ko, Jong Young Kim
  Journal of the Korean Society of Manufacturing Process Engineers.2020; 19(2): 1.     CrossRef
• Controlling In Vivo, Human Pulp Temperature Rise Caused by LED Curing Light Exposure
  DC Zarpellon, P Runnacles, C Maucoski, U Coelho, FA Rueggeberg, CAG Arrais
  Operative Dentistry.2019; 44(3): 235.     CrossRef
• Pulp Temperature Rise Induced by Light-Emitting Diode Light-Curing Units Using an Ex Vivo Model
  Alexandra Vinagre, João Ramos, Clara Rebelo, José Basto, Ana Messias, Nélia Alberto, Rogério Nogueira
  Materials.2019; 12(3): 411.     CrossRef
• The cooling efficiency of different dental high-speed handpiece coolant port designs
  Helene Chua, Joanne Jung Eun Choi, Rishi Sanjay Ramani, Ritu Ganjigatti, John Neil Waddell
  Heliyon.2019; 5(8): e02185.     CrossRef
• Polymerisation Shrinkage Profiling of Dental Composites using Optical Fibre Sensing and their Correlation with Degree of Conversion and Curing Rate
  Ginu Rajan, Raju Raju, Sagar Jinachandran, Paul Farrar, Jiangtao Xi, B. Gangadhara Prusty
  Scientific Reports.2019;[Epub]     CrossRef
• Tooth sectioning for coronectomy: how to perform?
  József Szalma, László Vajta, Lajos Olasz, Edina Lempel
  Clinical Oral Investigations.2019; 23(2): 519.     CrossRef
• Dentistry Applications of Fiber Bragg Gratings: Irradiation Protocols for Bulk Fill Flow Dental Composites
  Ana Paula Gebert de Oliveira Franco, Manoella Maria Machado Costa, Leandro Zen Karam, Osnara Maria Mongruel Gomes, Hypolito Jose Kalinowski
  Journal of Lightwave Technology.2019; 37(18): 4881.     CrossRef
• In Vitro Analysis of Techniques that Alter the Surface Hardness of a Glass Ionomer Restorative Material
  Riaan Mulder, Naeemah Noordien, Shaun Rossouw, Luzaan van Zyl
  The Journal of Contemporary Dental Practice.2019; 20(12): 1362.     CrossRef
• Changes in the radicular pulp-dentine complex in healthy intact teeth and in response to deep caries or restorations: A histological and histobacteriological study
  Domenico Ricucci, Simona Loghin, Li-na Niu, Franklin R. Tay
  Journal of Dentistry.2018; 73: 76.     CrossRef
• Effect of Irradiance and Exposure Duration on Temperature and Degree of Conversion of Dual-Cure Resin Cement for Ceramic Restorations
  JS Shim, SH Han, N Jha, ST Hwang, W Ahn, JY Lee, JJ Ryu
  Operative Dentistry.2018; 43(6): E280.     CrossRef
• Protective Effects of Base Cements against Intrapulpal Temperature Rise during Curing of Composite Resins: An In Vitro Study by Pulpal Blood Microcirculation Model
  Ihsan F Ertugrul, Basak Yazkan, Ceylan Ç Ertugrul
  International Journal of Experimental Dental Science.2018; 7(2): 85.     CrossRef
• Thermal imaging of the pulp during residual adhesive removal
  Gökmen Kurt, Nisa Gül, Özgür Er, Gülşen Çakmak, Emre Bendeş, Veysel Aslantaş
  Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie.2017; 78(4): 330.     CrossRef
• Influence of the material for preformed moulds on the polymerization temperature of resin materials for temporary FPDs
  Philipp-Cornelius Pott, Hans Schmitz-Wätjen, Meike Stiesch, Michael Eisenburger
  The Journal of Advanced Prosthodontics.2017; 9(4): 294.     CrossRef
• Light curing in dentistry and clinical implications: a literature review
  Frederick Allen RUEGGEBERG, Marcelo GIANNINI, Cesar Augusto Galvão ARRAIS, Richard Bengt Thomas PRICE
  Brazilian Oral Research.2017;[Epub]     CrossRef
• Intrapulpal temperature changes during curing of different bulk-fill restorative materials
  Elif YASA, Cigdem ATALAYIN, Gamze KARACOLAK, Tugrul SARI, L. Sebnem TURKUN
  Dental Materials Journal.2017; 36(5): 566.     CrossRef
• Can Mineral Trioxide Aggregate and Nanoparticulate EndoSequence Root Repair Material Produce Injurious Effects to Rat Subcutaneous Tissues?
  Wafaa A. Khalil, Siham K. Abunasef
  Journal of Endodontics.2015; 41(7): 1151.     CrossRef
• Comparison of photopolymerization temperature increases in internal and external positions of composite and tooth cavities in real time: Incremental fillings of microhybrid composite vs. bulk filling of bulk fill composite
  Ryan Jin-Young Kim, Sung-Ae Son, Ji-Yun Hwang, In-Bog Lee, Deog-Gyu Seo
  Journal of Dentistry.2015; 43(9): 1093.     CrossRef
• Real-Time Analysis of Temperature Changes in Composite Increments and Pulp Chamber during Photopolymerization
  Ryan Jin-Young Kim, In-Bog Lee, Jin-Young Yoo, Su-Jung Park, Sin-Young Kim, Young-Ah Yi, Ji-Yun Hwang, Deog-Gyu Seo
  BioMed Research International.2015; 2015: 1.     CrossRef
• Temperature changes under demineralized dentin during polymerization of three resin-based restorative materials using QTH and LED units
  Sayed-Mostafa Mousavinasab, Maryam Khoroushi, Mohammadreza Moharreri, Mohammad Atai
  Restorative Dentistry & Endodontics.2014; 39(3): 155.     CrossRef
• Comparison of Exothermic Release during the Polymerization of Four Materials used to fabricate Provisional Restorations
  Minu Raju
  International Journal of Prosthodontics and Restorative Dentistry.2014; 4(1): 1.     CrossRef

Since the introduction of restorative dental composites, their physical properties have been significantly improved. However, polymerization shrinkage is still a major drawback. Many efforts have been made to develop a low shrinking composite, and silorane-based composites have recently been introduced into the market. In addition, many different methods have been developed to measure the polymerization shrinkage.

In this study, we developed a new method to measure the linear polymerization shrinkage of composites without direct contact to a specimen using a particle tracking method with computer vision. The shrinkage kinetics of a commercial silorane-based composite (P90) and two conventional methacrylate-based composites (Z250 and Z350) were investigated and compared. The results were as follows:

The linear shrinkage of composites was 0.33-1.41%. Shrinkage was lowest for the silorane-based (P90) composite, and highest for the flowable Z350 composite.

Citations

Citations to this article as recorded by  

• Effect of layering methods, composite type, and flowable liner on the polymerization shrinkage stress of light cured composites
  Youngchul Kwon, Jack Ferracane, In-Bog Lee
  Dental Materials.2012; 28(7): 801.     CrossRef

Diabetes Mellitus (DM) is a syndrome accompanied with the abnormal secretion or function of insulin, a hormone that plays a vital role in controlling the blood glucose level (BGL). Type 1and 2 DM are most common form and the prevalence of the latter is recently increasing. The aim of this article was to assess whether Type 2 DM could act as a predisposing risk factor on the pulpo-periapical pathogenesis. Previous literature on the pathologic changes of blood vessels in DM was thoroughly reviewed. Furthermore, a histopathologic analysis of artificially-induced periapical specimens obtained from Type 2 diabetic and DM-resistant rats was compared. Histopathologic results demonstrate that the size of periapical bone destruction was larger and the degree of pulpal inflammation was more severe in diabetic rats, indicating that Type 2 DM itself can be a predisposing risk factor that makes the host more susceptible to pulpal infection. The possible reasons may be that in diabetic state the lumen of pulpal blood vessels are thickened by atheromatous deposits, and microcirculation is hindered. The function of polymorphonuclear leukocyte is also impaired and the migration of immune cells is blocked, leading to increased chance of pulpal infection. Also, lack of collateral circulation of pulpal blood vessels makes the pulp more susceptible to infection. These decrease the regeneration capacity of pulpal cells or tissues, delaying the healing process. Therefore, when restorative treatment is needed in Type 2 DM patients, dentists should minimize irritation to the pulpal tissue un der control of BGL.

Citations

Citations to this article as recorded by  

• Pulp necrosis following luxated injury to teeth in a patient with uncontrolled type II diabetes mellitus: a case report
  Haneol Shin, Seung-Jong Lee, Il-Young Jung, Chan-Young Lee
  Restorative Dentistry & Endodontics.2012; 37(1): 61.     CrossRef

The aim of this study was to evaluate the marginal and internal gaps in CEREC3 CAD/CAM inlays of three different preparation designs. CEREC3 Inlays of three different preparation designs (n = 10) were fabricated according to Group I-conventional functional cusp capping/shoulder preparation, Group II-horizontal reduction of cusps and Group III-complete reduction of cusps/shoulder preparation. After cementation of inlays, the bucco-lingual cross section was performed through the center of tooth. Cross section images of 20 magnifications were obtained through the stereomicroscope. The gaps were measured using the Leica application suite software at each reference point. Statistical analysis was performed using one-way ANOVA and Tukey's test (α<0.05).

The marginal gaps ranged from 80.0 to 97.8 µm for Group I, 42.0 to 194.8 µm for Group II, 51.0 to 80.2 µm for Group III. The internal gaps ranged from 90.5 to 304.1 µm for Group I, 80.0 to 274.8 µm for Group II, 79.7 to 296.7 µm for Group III. The gaps of each group were the smallest on the margin and the largest on the horizontal wall. For the CEREC3 CAD/CAM inlays, the simplified designs (groups II and III) did not demonstrate superior results compared to the traditional cusp capping design (group I).

Citations

Citations to this article as recorded by  

• Influence of preparation design on fit and ceramic thickness of CEREC 3 partial ceramic crowns after cementation
  Jae-Hoon Kim, Byeong-Hoon Cho, Jin-Hee Lee, Soo-Jung Kwon, Young-Ah Yi, Yooseok Shin, Byoung-Duck Roh, Deog-Gyu Seo
  Acta Odontologica Scandinavica.2015; 73(2): 107.     CrossRef

The purpose of this study was to evaluate the effect of instrument compliance on the polymerization shrinkage stress measurements of dental composites. The contraction strain and stress of composites during light curing were measured by a custom made stress-strain analyzer, which consisted of a displacement sensor, a cantilever load cell and a negative feedback mechanism. The instrument can measure the polymerization stress by two modes: with compliance mode in which the instrument compliance is allowed, or without compliance mode in which the instrument compliance is not allowed.

A flowable (Filtek Flow: FF) and two universal hybrid (Z100: Z1 and Z250: Z2) composites were studied. A silane treated metal rod with a diameter of 3.0 mm was fixed at free end of the load cell, and other metal rod was fixed on the base plate. Composite of 1.0 mm thickness was placed between the two rods and light cured. The axial shrinkage strain and stress of the composite were recorded for 10 minutes during polymerization, and the tensile modulus of the materials was also determined with the instrument. The statistical analysis was conducted by ANOVA, paired t-test and Tukey's test (α<0.05).

There were significant differences between the two measurement modes and among materials. With compliance mode, the contraction stress of FF was the highest: 3.11 (0.13), followed by Z1: 2.91 (0.10) and Z2: 1.94 (0.09) MPa. When the instrument compliance is not allowed, the contraction stress of Z1 was the highest: 17.08 (0.89), followed by FF: 10.11 (0.29) and Z2: 9.46 (1.63) MPa. The tensile modulus for Z1, Z2 and FF was 2.31 (0.18), 2.05 (0.20), 1.41 (0.11) GPa, respectively. With compliance mode, the measured stress correlated with the axial shrinkage strain of composite; while without compliance the elastic modulus of materials played a significant role in the stress measurement.

Citations

Citations to this article as recorded by  

• Effects of cuspal compliance and radiant emittance of LED light on the cuspal deflection of replicated tooth cavity
  Chang-Ha LEE, In-Bog LEE
  Dental Materials Journal.2021; 40(3): 827.     CrossRef
• Polymerization Shrinkage and Stress of Silorane-based Dental Restorative Composite
  In-Bog Lee, Sung-Hwan Park, Hyun-Jeong Kweon, Ja-Uk Gu, Nak-Sam Choi
  Composites Research.2013; 26(3): 182.     CrossRef
• Evaluation of polymerization shrinkage stress in silorane-based composites
  Seung-Ji Ryu, Ji-Hoon Cheon, Jeong-Bum Min
  Journal of Korean Academy of Conservative Dentistry.2011; 36(3): 188.     CrossRef
• The change of the initial dynamic visco-elastic modulus of composite resins during light polymerization
  Min-Ho Kim, In-Bog Lee
  Journal of Korean Academy of Conservative Dentistry.2009; 34(5): 450.     CrossRef

The possibility of applying a bi-axial flexure strength test on composite resin was examined using three point and bi-axial flexure strength tests to measure the strength of the light-cured resin and to compare the relative reliability using the Weibull modulus.

The materials used in this study were light-curing restorative materials, MICRONEW™, RENEW® (Bisco, Schaumburg, USA). The bi-axial flexure strength measurements used the piston-on-3-ball test according to the regulations of the International Organization for Standardization (ISO) 6872 and were divided into 6 groups, where the radius of the specimens were 12 mm (radius connecting the 3-balls: 3.75 mm), 16 mm (radius connecting the 3-balls: 5 mm), and the thickness were 0.5 mm, 1 mm, 2 mm for each radius.

The bi-axial flexure strength of the MICRONEW™ and RENEW® were higher than the three point flexure strength and the Weibull modulus value were also higher in all of the bi-axial flexure strength groups, indicating that the bi-axial strength test is relatively less affected by experimental error.

In addition, the 2 mm thick specimens had the highest Weibull modulus values in the bi-axial flexure strength test, and the MICRONEW™ group showed no significant statistical difference (p > 0.05). Besides the 2 mm MICRONEW™ group, each group showed significant statistical differences (p < 0.05) according to the thickness of the specimen and the radius connecting the 3-balls.

The results indicate that for the 2 mm group, the bi-axial flexure strength test is a more reliable testing method than the three point flexure strength test.

Citations

Citations to this article as recorded by  

• Mechanical properties of CAD/CAM polylactic acid as a material for interim restoration
  Won-Il Choi, Lee-gang Yoo, Yu-ri Kim, Bock-Young Jung
  Heliyon.2023; 9(4): e15314.     CrossRef
• The comparisons of layers and the effect of additional firings on flexural strength and translucency of 5Y-ZP
  Hyung-Joon Kim, Soo-Yeon Shin
  Journal of Dental Rehabilitation and Applied Science.2021; 37(3): 111.     CrossRef
• Effect of coloring liquids on biaxial flexural strength of monolithic zirconia
  Chaeyul Jung, Min-Jeong Kim, Jae-Hyun Kim
  The Journal of Korean Academy of Prosthodontics.2021; 59(2): 190.     CrossRef
• Mechanical Properties and Reliability of Sand Casting 3D Printing Materials
  Hyeon Jin Son, Seongwan Jang, Hwan Jong Lee, Jeong Jik Yang, Yeong Geun Jeong, Chang-Jun Bae
  Korean Journal of Materials Research.2020; 30(1): 38.     CrossRef
• Comparison analysis of fracture load and flexural strength of provisional restorative resins fabricated by different methods
  Won-Tak Cho, Jae-Won Choi
  The Journal of Korean Academy of Prosthodontics.2019; 57(3): 225.     CrossRef
• Effect of Two Polishing Systems on Surface Roughness, Topography, and Flexural Strength of a Monolithic Lithium Disilicate Ceramic
  Mahshid Mohammadibassir, Mohammad Bagher Rezvani, Hossein Golzari, Elham Moravej Salehi, Mohammad Amin Fahimi, Mohammad Javad Kharazi Fard
  Journal of Prosthodontics.2019;[Epub]     CrossRef
• Characteristics according to the Amount of HAp Added in Resin for Tooth Repair
  Sungu Hwang, Jinhyuck Lim, Suchak Ryu
  Journal of the Korean Ceramic Society.2019; 56(6): 521.     CrossRef
• Flexural strength and microstructure of two lithium disilicate glass ceramics for CAD/CAM restoration in the dental clinic
  Suk-Ho Kang, Juhea Chang, Ho-Hyun Son
  Restorative Dentistry & Endodontics.2013; 38(3): 134.     CrossRef