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Silver nanoparticles in endodontics: recent developments and applications
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Aysenur Oncu, Yan Huang, Gulin Amasya, Fatma Semra Sevimay, Kaan Orhan, Berkan Celikten
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Restor Dent Endod 2021;46(3):e38. Published online July 1, 2021
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DOI: https://doi.org/10.5395/rde.2021.46.e38
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Abstract
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The elimination of endodontic biofilms and the maintenance of a leak-proof canal filling are key aspects of successful root canal treatment. Several materials have been introduced to treat endodontic disease, although treatment success is limited by the features of the biomaterials used. Silver nanoparticles (AgNPs) have been increasingly considered in dental applications, especially endodontics, due to their high antimicrobial activity. For the present study, an electronic search was conducted using MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and EMBASE. This review provides insights into the unique characteristics of AgNPs, including their chemical, physical, and antimicrobial properties; limitations; and potential uses. Various studies involving different application methods of AgNPs were carefully examined. Based on previous clinical studies, the synthesis, means of obtaining, usage conditions, and potential cytotoxicity of AgNPs were evaluated. The findings indicate that AgNPs are effective antimicrobial agents for the elimination of endodontic biofilms.
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Citations
Citations to this article as recorded by 
- Scoping review on the genotoxicity of silver nanoparticles in endodontics: therapeutic saviors or genetic saboteurs?
Galvin Sim Siang Lin, Widya Lestari, Mohd Haikal Muhamad Halil, Mohd Syafiq Abd Aziz Odontology.2025; 113(2): 457. CrossRef - Antimicrobial Effects of Formulations of Various Nanoparticles and Calcium Hydroxide as Intra-canal Medications Against Enterococcus faecalis: A Systematic Review
Seema H Bukhari, Dax Abraham, Shakila Mahesh Cureus.2024;[Epub] CrossRef - The Push-Out Bond Strength, Surface Roughness, and Antimicrobial Properties of Endodontic Bioceramic Sealers Supplemented with Silver Nanoparticles
Karla Navarrete-Olvera, Nereyda Niño-Martínez, Idania De Alba-Montero, Nuria Patiño-Marín, Facundo Ruiz, Horacio Bach, Gabriel-Alejandro Martínez-Castañón Molecules.2024; 29(18): 4422. CrossRef - Synergistic bactericidal activity of chlorhexidine loaded on positively charged ionic liquid-protected silver nanoparticles as a root canal disinfectant against Enterococcus faecalis: An ex vivo study
Abbas Abbaszadegan, Elham Tayebikhorami, Ahmad Gholami, Nazanin Bonyanpour, Bahar Asheghi, Sara Nikmanesh Journal of Ionic Liquids.2024; 4(2): 100117. CrossRef - Improving the Antimicrobial Potency of Berberine for Endodontic Canal Irrigation Using Polymeric Nanoparticles
Célia Marques, Liliana Grenho, Maria Helena Fernandes, Sofia A. Costa Lima Pharmaceutics.2024; 16(6): 786. CrossRef - A narrative review on application of metal and metal oxide nanoparticles in endodontics
Roohollah Sharifi, Ahmad Vatani, Amir Sabzi, Mohsen Safaei Heliyon.2024; 10(15): e34673. CrossRef - The Effectiveness of Silver Nanoparticles Mixed with Calcium Hydroxide against Candida albicans: An Ex Vivo Analysis
Maha Alghofaily, Jood Alfraih, Aljohara Alsaud, Norah Almazrua, Terrence S. Sumague, Sayed H. Auda, Fahd Alsalleeh Microorganisms.2024; 12(2): 289. CrossRef - Evaluation of the efficacy of a novel disinfecting material on the surface topography of gutta-percha: An in vitro study
KHanisha Reddy, Lekshmi Chandran, TMurali Mohan, K Sudha, DL Malini, Bonney Dominic Journal of Conservative Dentistry.2023; 26(1): 94. CrossRef - Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review
Farzaneh Afkhami, Parisa Forghan, James L. Gutmann, Anil Kishen Pharmaceutics.2023; 15(3): 715. CrossRef - Nanopartículas antimicrobianas en endodoncia: Revisión narrativa
Gustavo Adolfo Tovar Rangel , Fanny Mildred González Sáenz , Ingrid Ximena Zamora Córdoba , Lina María García Zapata Revista Estomatología.2023;[Epub] CrossRef - Functionalized Nanoparticles: A Paradigm Shift in Regenerative Endodontic Procedures
Vinoo Subramaniam Ramachandran, Mensudar Radhakrishnan, Malathi Balaraman Ravindrran, Venkatesh Alagarsamy, Gowri Shankar Palanisamy Cureus.2022;[Epub] CrossRef
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Micro-computed tomographic assessment of the shaping ability of the One Curve, One Shape, and ProTaper Next nickel-titanium rotary systems
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Pelin Tufenkci, Kaan Orhan, Berkan Celikten, Burak Bilecenoglu, Gurkan Gur, Semra Sevimay
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Restor Dent Endod 2020;45(3):e30. Published online May 22, 2020
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DOI: https://doi.org/10.5395/rde.2020.45.e30
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Abstract
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- Objectives
This micro-computed tomographic (CT) study aimed to compare the shaping abilities of ProTaper Next (PTN), One Shape (OS), and One Curve (OC) files in 3-dimensionally (3D)-printed mandibular molars. Materials and MethodsIn order to ensure standardization, 3D-printed mandibular molars with a consistent mesiobuccal canal curvature (45°) were used in the present study (n = 18). Specimens were instrumented with the OC, OS, or PTN files. The teeth were scanned pre- and post-instrumentation using micro-CT to detect changes of the canal volume and surface area, as well as to quantify transportation of the canals after instrumentation. Two-way analysis of variance was used for statistical comparisons. ResultsNo statistically significant differences were found between the OC and OS groups in the changes of the canal volume and surface area before and after instrumentation (p > 0.05). The OC files showed significantly less transportation than the OS or PTN systems for the apical section (p < 0.05). In a comparison of the systems, similar values were found at the coronal and middle levels, without any significant differences (p > 0.05). ConclusionsThese 3 instrumentation systems showed similar shaping abilities, although the OC file achieved a lesser extent of transportation in the apical zone than the OS and PTN files. All 3 file systems were confirmed to be safe for use in mandibular mesial canals.
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Citations
Citations to this article as recorded by 
- A Comparative Evaluation of the Efficiencies of Different Rotary File Systems in Terms of Remaining Dentin Thickness Using Cone Beam Computed Tomography: An In Vitro Study
Vivek P Vadera , Sandhya K Punia, Saleem D Makandar, Rahul Bhargava, Pradeep Bapna Cureus.2024;[Epub] CrossRef - Comparison of Different Rotary Nickel–titanium Systems to Evaluate Coronal Leakage of Root Canals: An in Vitro Study
Rasha M. Al-Shamaa Dental Hypotheses.2023; 14(3): 81. CrossRef - Comparative evaluation of canal transportation and canal centering ability in oval canals with newer nickel–titanium rotary single file systems – A cone-beam computed tomography study
SimarKaur Manocha, SuparnaGanguly Saha, RollyS Agarwal, Neelam Vijaywargiya, MainakKanti Saha, Anjali Surana Journal of Conservative Dentistry.2023; 26(3): 326. CrossRef - Accumulated Hard Tissue Debris and Root Canal Shaping Profiles Following Instrumentation with Gentlefile, One Curve, and Reciproc Blue
Chi Wai Chan, Virginia Rosy Romeo, Angeline Lee, Chengfei Zhang, Prasanna Neelakantan, Eugenio Pedullà Journal of Endodontics.2023; 49(10): 1344. CrossRef - Comparative evaluation of canal transportation and centering ability of rotary and reciprocating file systems using cone-beam computed tomography: An in vitro study
Tanisha Singh, Manju Kumari, Rohit Kochhar Journal of Conservative Dentistry.2023; 26(3): 332. CrossRef - Retreatability of Bioceramic Sealer Using One Curve Rotary File Assessed by Microcomputed Tomography
Dina G Mufti, Saad A Al-Nazhan The Journal of Contemporary Dental Practice.2022; 22(10): 1175. CrossRef - Micro-computed tomography in preventive and restorative dental research: A review
Mehrsima Ghavami-Lahiji, Reza Tayefeh Davalloo, Gelareh Tajziehchi, Paria Shams Imaging Science in Dentistry.2021; 51(4): 341. CrossRef
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