Restorative Dentistry & Endodontics

Statistical Review Article

Practical considerations and methods for determining sample size to estimate a population mean: a narrative review: Mohamad Adam Bujang; J Korean Acad Conserv Dent ;Published online August 12, 2026; DOI: https://doi.org/10.5395/rde.2026.51.e41 [Epub ahead of print]

Abstract PDF PubReader ePub: Sample size determination plays a crucial role in ensuring the validity and precision of research findings. This paper reviews the concept, rationale, and application of the sample size formula for estimating the mean of a population. It outlines the theoretical foundation, practical calculation steps, and appropriate contexts for its use in descriptive and estimation-based studies. This formula is often overlooked, as many researchers focus primarily on hypothesis testing frameworks rather than estimation approaches. Although it is a classical method, it remains highly relevant and essential in contemporary research. Therefore, this paper highlights the importance of this formula across various research settings and provides detailed guidance on how to compute the required sample size accurately. By doing so, it aims to support proper sample size planning, strengthen research design validity, and ultimately enhance the quality and credibility of scientific investigations.

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