Restorative Dentistry & Endodontics

Research Articles

Histological evaluation of pulp response to alendronate and Biodentine as pulp capping agents: an animal study: Thangavel Boopathi, Sekar Manimaran, Joseline Charles Kerena, Mathew Sebeena, Kumaravadivel Karthick, Natesan Thangaraj Deepa; Restor Dent Endod 2024;49(4):e39. Published online October 29, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e39

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This study aimed to comparatively assess the histological response of the pulp toward alendronate and Biodentine in a direct pulp capping procedure.
Materials and Methods
Twenty-four anterior teeth from 6 New Zealand rabbits were used in this study. Firstly, all rabbits were anesthetized according to their weight. Class V cavities were prepared on the buccal surfaces of anterior teeth. A pin-point exposure of the pulp was then made using a small, sterile round carbide bur and bleeding was arrested with a saline-soaked, sterile cotton pellet. The teeth under study were divided into 2 groups (n = 12). The intentionally exposed pulp was capped with alendronate (Group 1) and Biodentine (Group 2), correspondingly. After 30 days, all rabbits were euthanized; the teeth under study were extracted and taken up for histological analysis.
Results
Biodentine showed an intact, very dense dentin bridge formation with a uniform odontoblast (OD) layer pattern and mild or absent inflammatory response whereas specimens capped with alendronate demonstrated a dense dentin bridge formation with non-uniform OD layer pattern and mild to moderate inflammatory response.
Conclusions
Biodentine showed more biocompatibility than alendronate. However, alendronate can initiate reparative dentin formation and may be used as an alternative pulp capping agent.

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Effects of a relined fiberglass post with conventional and self-adhesive resin cement: Wilton Lima dos Santos Junior, Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Luís Roberto Marcondes Martins; Restor Dent Endod 2024;49(2):e18. Published online March 27, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e18

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Objectives

This study was conducted to evaluate the mechanical properties of relined and non-relined fiberglass posts when cemented to root canal dentin using a conventional dual-cure resin cement or a self-adhesive resin cement.

Materials and Methods

Two types of resin cements were utilized: conventional and self-adhesive. Additionally, 2 cementation protocols were employed, involving relined and non-relined fiberglass posts. In total, 72 bovine incisors were cemented and subjected to push-out bond strength testing (n = 10) followed by failure mode analysis. The cross-sectional microhardness (n = 5) was assessed along the root canal, and interface analyses (n = 3) were conducted using scanning electron microscopy (SEM). Data from the push-out bond strength and cross-sectional microhardness tests were analyzed via 3-way analysis of variance and the Bonferroni post-hoc test (α = 0.05).

Results

For non-relined fiberglass posts, conventional resin cement exhibited higher push-out bond strength than self-adhesive cement. Relined fiberglass posts yielded comparable results between the resin cements. Type II failure was the most common failure mode for both resin cements, regardless of cementation protocol. The use of relined fiberglass posts improved the cross-sectional microhardness values for both cements. SEM images revealed voids and bubbles in the incisors with non-relined fiberglass posts.

Conclusions

Mechanical properties were impacted by the cementation protocol. Relined fiberglass posts presented the highest push-out bond strength and cross-sectional microhardness values, regardless of the resin cement used (conventional dual-cure or self-adhesive). Conversely, for non-relined fiberglass posts, the conventional dual-cure resin cement yielded superior results to the self-adhesive resin cement.

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Push-Out Bond Strength of Different Luting Cements Following Post Space Irrigation with 2% Chitosan: An In Vitro Study
Shimaa Rifaat, Ahmed Rahoma, Hind Muneer Alharbi, Sawsan Jamal Kazim, Shrouq Ali Aljuaid, Basmah Omar Alakloby, Faraz A. Farooqi, Noha Taymour
Prosthesis.2025; 7(1): 18. CrossRef

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Single-session associative protocol for dentin hypersensitivity management: a 1-year randomized, blinded clinical study: Thayna Carolina Zeni, Poliana Maria de Faveri Cardoso, Rafael da Silva Vanolli, Márcio José Mendonça, Julio Katuhide Ueda, Veridiana Camilotti; Restor Dent Endod 2024;49(2):e15. Published online March 20, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e15

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Objectives

This study aimed to establish a single-session associative protocol for non-restorative management of dentin hypersensitivity (DH).

Materials and Methods

Twenty-four individuals with DH and a minimum sensitivity level of 4 on the visual analog scale (VAS) were selected. The study was conducted in a split-mouth design, with each participant (n = 20) having at least 1 affected tooth in all quadrants. The management protocols consisted of control group: universal adhesive, Neural Desensitizing Protocol group: 5% potassium nitrate, Mixed Desensitizing Protocol (PAM) group: 5% sodium fluoride and 5% potassium nitrate, Remineralizing Desensitizing Protocol (PDR) group: surface-partially reacted glass technology photopolymerizable varnish. Evaluations were performed immediately after application, at 1 week, 1 month, 2 months, and 12 months using the VAS sensitivity test.

Results

The scores were subjected to statistical analysis using the Friedman test (p < 0.05), Durbin-Conover test (p < 0.05), and Wilcoxon test (p < 0.05). At the 12-month evaluation, all groups showed statistically significant differences compared to the initial assessment. For the evaluation after 12 months, there was a statistically significant difference between the PAM group, the control group, and the PDR group.

Conclusions

It can be concluded that all groups were effective in controlling DH, but there were significant results in the control group and PDR group. The clinical relevance of this study is to demonstrate that the application of single-session desensitizing protocols can be effective in controlling DH for up to 12 months.

Trial Registration

Brazilian Clinical Trials Registry Identifier: RBR-4r63d7s

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Desensitizing efficacy of a universal dentin adhesive containing mesoporous bioactive glass on dentin hypersensitivity: a randomized clinical trial with a split-mouth model
Hyun-Jung Kim, Soram Oh, Jiyoung Kwon, Kyoung-Kyu Choi, Ji-Hyun Jang, Duck-Su Kim
Scientific Reports.2024;[Epub] CrossRef

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Pomegranate extract on eroded dentin: antioxidant action, bond strength and morphology of the adhesive interface after aging: Thiago Vinícius Cortez, Nathália Mancioppi Cerqueira, Julia Adornes Gallas, Wanderley Pereira Oliveira, Silmara Aparecida Milori Corona, Aline Evangelista Souza-Gabriel; Restor Dent Endod 2024;49(1):e9. Published online January 26, 2024; DOI: https://doi.org/10.5395/rde.2024.49.e9

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Objectives

This study aimed to evaluate the effect of pomegranate solution (Punica granatum) on eroded dentin through antioxidant action, shear bond strength (SBS) and interface morphology.

Materials and Methods

The 10% pomegranate peel extract was prepared by the lyophilization method. Punicalagin polyphenol was confirmed by high-performance liquid chromatography. Antioxidant activity was evaluated by capturing the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. For the SBS, 48 dentin fragments were divided into sound or eroded, and subdivided according to the pretreatment (n = 12): water or P. granatum. The surfaces were restored with self-etch adhesive and a bulk-fill resin (Ecosite; DMG). The SBS was done immediately (24 hours) and after thermal cycling + water storage (12 months). For scanning electron microscopy, 48 dentin fragments (24 sound and 24 eroded) received the same treatments as for SBS (n = 6), and they were analyzed after 24 hours and 12 months.

Results

The P. granatum had antioxidant action similar (p = 0.246) to the phenolic standard antioxidants. After 24 hours, eroded dentin had lower SBS than sound dentin (p < 0.001), regardless of the pretreatment. After 12 months, P. granatum maintained the SBS of sound dentin (13.46 ± 3.42 MPa) and eroded dentin (10.96 ± 1.90 MPa) statistically similar. The lowest values were found on eroded dentin treated with water (5.75 ± 1.65 MPa) (p < 0.001). P. granatum on eroded dentin caused peritubular demineralization and hybrid layer with resin tags.

Conclusions

The pomegranate extract had antioxidant action and preserved the adhesive interface of the eroded dentin.

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Effect of pomegranate solution alone or combined with chlorhexidine against oral multispecies biofilm
J. A. Gallas, L. L. Pelozo, S. A. M. Corona, Y. Shen, M. Haapasalo, M. D. Sousa‐Neto, A. E. Souza‐Gabriel
International Endodontic Journal.2024; 57(12): 1819. CrossRef
The effect of resveratrol application on the micro-shear bond strength of adhesive to bleached enamel
Esra Cengiz-Yanardag, Izgen Karakaya
Scientific Reports.2024;[Epub] CrossRef

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Effect of dentin roughening and type of composite material on the restoration of non-carious cervical lesions: an in vivo study with 18 months of follow-up: Sanjana Verma, Rakesh Singla, Gurdeep Singh Gill, Namita Jain; Restor Dent Endod 2023;48(4):e35. Published online October 17, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e35

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Objectives

The purpose of this study was to evaluate the impact of dentin roughening and the type of composite resin used (either bulk-fill flowable or nanohybrid) on the restoration of non-carious cervical lesions (NCCLs) with an 18-month follow-up period.

Materials and Methods

This prospective split-mouth study included 36 patients, each with a minimum of 4 NCCLs. For each patient, 4 types of restorations were performed: unroughened dentin with nanohybrid composite, unroughened dentin with bulk-fill flowable composite, roughened dentin with nanohybrid composite, and roughened dentin with bulk-fill flowable composite. A universal bonding agent (Tetric N Bond Universal) was applied in self-etch mode for all groups. The restorations were subsequently evaluated at 6, 12, and 18 months in accordance with the criteria set by the FDI World Dental Federation. Inferential statistics were computed using the Friedman test, with the level of statistical significance established at 0.05.

Results

The 4 groups exhibited no significant differences in relation to fracture and retention, marginal staining, marginal adaptation, postoperative hypersensitivity, or the recurrence of caries at any follow-up point.

Conclusions

Within the limitations of the present study, over an 18-month follow-up period, no significant difference was present in the clinical performance of bulk-fill flowable and nanohybrid composite restorations of non-carious cervical lesions. This held true regardless of whether dentin roughening was performed.

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Clinical performance of preheating thermoviscous composite resin for non-carious cervical lesions restoration: A 24-month randomized clinical trial
Michael Willian Favoreto, Taynara de Souza Carneiro, Romina Ñaupari-Villasante, Deisy Cristina Cordeiro, Gabriel David Cochinski, Thais Vilalba Paniagua Machado do Nascimento, Thalita de Paris Matos, Matheus Coelho Bandeca, Alessandra Reis, Alessandro D.
Journal of Dentistry.2024; 144: 104930. CrossRef
Die Zahnhalsfüllung
Roland Frankenberger
Der Freie Zahnarzt.2024; 68(7-8): 70. CrossRef

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Review Article

Stem cell-derived exosomes for dentin-pulp complex regeneration: a mini-review: Dina A. Hammouda, Alaa M Mansour, Mahmoud A. Saeed, Ahmed R. Zaher, Mohammed E. Grawish; Restor Dent Endod 2023;48(2):e20. Published online May 3, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e20

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This mini-review was conducted to present an overview of the use of exosomes in regenerating the dentin-pulp complex (DPC). The PubMed and Scopus databases were searched for relevant articles published between January 1, 2013 and January 1, 2023. The findings of basic in vitro studies indicated that exosomes enhance the proliferation and migration of mesenchymal cells, as human dental pulp stem cells, via mitogen-activated protein kinases and Wingless-Int signaling pathways. In addition, they possess proangiogenic potential and contribute to neovascularization and capillary tube formation by promoting endothelial cell proliferation and migration of human umbilical vein endothelial cells. Likewise, they regulate the migration and differentiation of Schwann cells, facilitate the conversion of M1 pro-inflammatory macrophages to M2 anti-inflammatory phenotypes, and mediate immune suppression as they promote regulatory T cell conversion. Basic in vivo studies have indicated that exosomes triggered the regeneration of dentin-pulp–like tissue, and exosomes isolated under odontogenic circumstances are particularly strong inducers of tissue regeneration and stem cell differentiation. Exosomes are a promising regenerative tool for DPC in cases of small pulp exposure or for whole-pulp tissue regeneration.

Citations

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Cell Homing Strategies in Regenerative Endodontic Therapy
David Kim, Sahng G. Kim
Cells.2025; 14(3): 201. CrossRef
Exosomes as Promising Therapeutic Tools for Regenerative Endodontic Therapy
Qingyue Kong, Yujie Wang, Nan Jiang, Yifan Wang, Rui Wang, Xiaohan Hu, Jing Mao, Xin Shi
Biomolecules.2024; 14(3): 330. CrossRef
Role and Molecular Mechanism of miR-586 in the Differentiation of Dental Pulp Stem Cells into Odontoblast-like Cells
Gang Pan, Qianwen Zhou, Chenhua Pan, Yingxue Zhang
Cell Biochemistry and Biophysics.2024; 83(1): 507. CrossRef

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Research Articles

Effect of an aluminum chloride hemostatic agent on the dentin shear bond strength of a universal adhesive: Sujin Kim, Yoorina Choi, Sujung Park; Restor Dent Endod 2023;48(2):e14. Published online March 22, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e14

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Objectives

This study investigated the effect of an aluminum chloride hemostatic agent on the shear bond strength (SBS) of a universal adhesive to dentin.

Materials and Methods

Eighty extracted human molars were trimmed at the occlusal dentin surfaces and divided mesiodistally. According to hemostatic agent application, specimens were randomly allocated into control (C) and hemostatic agent (Traxodent; H) groups. Each group was divided into 4 subgroups according to the adhesive system (n = 20): Scotchbond Multi-Purpose (SBER), Clearfil SE Bond (CLSE), All-Bond Universal etch-and-rinse mode (ALER), and All-Bond Universal self-etch mode (ALSE). SBS was measured for half of the specimens at 24 hours, and the other half were thermocycled in water baths (group T). Fracture surfaces were examined to determine the failure mode. The SBS was measured, and data were analyzed using 1-way analysis of variance, the Student’s t-test, and the Tukey honestly significant difference test (p = 0.05).

Results

No significant differences in SBS were found between groups C and H for any adhesive system at 24 hours. After thermocycling, a statistically significant difference was observed between CT+ALSE and HT+ALSE (p < 0.05). When All-Bond Universal was applied to hemostatic agent-contaminated dentin, the SBS of H+ALSE was significantly lower than that of H+ALER (p < 0.05). The SBER subgroups showed no significant differences in SBS regardless of treatment and thermocycling.

Conclusions

When exposed dentin was contaminated by an aluminum chloride hemostatic agent before dentin adhesive treatment, application of All-Bond Universal in etch-and-rinse mode was superior to self-etch mode.

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Emalje- og dentinadhesiver: Avgjørende faser i klinisk behandling
Torgils Lægreid, Tom Paulseth, Arne Lund
Den norske tannlegeforenings Tidende.2024;[Epub] CrossRef

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Epigallocatechin-3-gallate prior to composite resin in abfraction lesions: a split-mouth randomized clinical trial: Luísa Valente Gotardo Lara Alves, Lisiane Martins Fracasso, Thiago Vinicius Cortez, Aline Evangelista Souza-Gabriel, Silmara Aparecida Milori Corona; Restor Dent Endod 2023;48(2):e13. Published online March 20, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e13

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Natural extracts have been investigated as a biomimetic strategy to mechanically strengthen the collagen network and control the biodegradation of extracellular matrix. This study evaluated the effect of epigallocatechin-3-gallate (EGCG) on abfraction lesions prior to the composite resin.
Materials and Methods
The sample consisted of 30 patients (aged between 28 and 60 years) with abfraction lesions located in 2 homologous premolars. The teeth were randomly assigned according to dentin treatment: 0.02% EGCG solution or distilled water (control). After enamel acid etching, the solutions were applied immediately for 1 minute. The teeth were restored with Universal Adhesive (3M) and Filtek Z350 XT (3M). Analyzes were done by 2 independent examiners using modified USPHS (retention, secondary caries, marginal adaptation, and postoperative sensitivity) and photographic (color, marginal pigmentation, and anatomical form) criteria at baseline (7 days) and final (18 months). The data analysis used Friedman and Wilcoxon signed-rank tests (α = 0.05).
Results
At baseline, all restorations were evaluated as alpha for all criteria. After 18 months, restorations were evaluated as alpha for secondary caries, color, and marginal pigmentation. There was significant difference between baseline and 18 months (p = 0.009) for marginal adaptation and postoperative sensitivity (p = 0.029), but no significant difference were verified between treatments (p = 0.433). The EGCG group had a restoration retention rate of 93.3%, while the control group had 96.7%.
Conclusions
The application of EGCG solution on abfraction lesions did not significantly influence the survival of the restorations based on clinical and photographic criteria.

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Dentinal tubule penetration of sodium hypochlorite in root canals with and without mechanical preparation and different irrigant activation methods: Renata Aqel de Oliveira, Theodoro Weissheimer, Gabriel Barcelos Só, Ricardo Abreu da Rosa, Matheus Albino Souza, Rodrigo Gonçalves Ribeiro, Marcus Vinicius Reis Só; Restor Dent Endod 2023;48(1):e1. Published online December 1, 2022; DOI: https://doi.org/10.5395/rde.2023.48.e1

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Objectives

This study evaluated the dentinal penetration depth of 2.5% sodium hypochlorite (NaOCl) in root canals with and without preparation and different irrigant activation protocols.

Materials and Methods

Sixty-three bovine mandibular incisors were randomly allocated to 6 groups (n = 10): G1, preparation + conventional needle irrigation (CNI); G2, preparation + passive ultrasonic irrigation (PUI); G3, preparation + Odous Clean (OC); G4, no preparation + CNI; G5, no preparation + PUI; G6, no preparation + OC; and CG (negative control; n = 3). Samples were filled with crystal violet for 72 hours. Irrigant activation was performed. Samples were sectioned perpendicularly along the long axis, 3 mm and 7 mm from the apex. Images of the root thirds of each block were captured with a stereomicroscope and analyzed with an image analysis software. One-way analysis of variance, followed by the Tukey post hoc test, and the Student’s t-test were used for data analysis, with a significance level of 5%.

Results

The NaOCl penetration depth was similar when preparation was performed, regardless of the method of irrigation activation (p > 0.05). In the groups without preparation, G6 showed greater NaOCl penetration depth (p < 0.05). The groups without preparation had a greater NaOCl penetration depth than those with preparation (p = 0.0019).

Conclusions

The NaOCl penetration depth was similar in groups with root canal preparation. Without root canal preparation, OC allowed deeper NaOCl penetration. The groups without preparation had greater NaOCl penetration than those undergoing root canal preparation.

Citations

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Impact of different activation procedures on sodium hypochlorite penetration into dentinal tubules after endodontic retreatment via confocal laser scanning microscopy
Betul Gunes, Kübra Yeşildal Yeter, Yasin Altay
BMC Oral Health.2024;[Epub] CrossRef
Debridement ability of the WaveOne Gold and TruNatomy systems in the apical third of root canals: ex vivo assessment
Sara Carvalho Avelar de Oliveira, Carlos Eduardo da Silveira Bueno, Rina Andréa Pelegrine, Carlos Eduardo Fontana, Alexandre Sigrist de Martin, Carolina Pessoa Stringheta
Brazilian Dental Journal.2024;[Epub] CrossRef
Combined effect of electrical energy and graphene oxide on Enterococcus faecalis biofilms
Myung-Jin LEE, Mi-Ah KIM, Kyung-San MIN
Dental Materials Journal.2023; 42(6): 844. CrossRef

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Resin infiltrant protects deproteinized dentin against erosive and abrasive wear: Ana Theresa Queiroz de Albuquerque, Bruna Oliveira Bezerra, Isabelly de Carvalho Leal, Maria Denise Rodrigues de Moraes, Mary Anne S. Melo, Vanara Florêncio Passos; Restor Dent Endod 2022;47(3):e29. Published online July 1, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e29

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Objectives

This study aimed to investigate the anti-erosive/abrasive effect of resin infiltration of previous deproteinized dentin.

Materials and Methods

Dentin slabs were randomly assigned to 3 groups (n = 15): Control (no deproteinization; no resin infiltrant applied), RI (no deproteinization; resin infiltrant applied), and DRI (deproteinization; resin infiltrant applied). After undergoing the assigned treatment, all slabs were subjected to an in vitro cycling model for 5 days. The specimens were immersed in citric acid (0.05 M, pH = 3.75; 60 seconds; 3 times/day) and brushed (150 strokes). Between the challenges, the specimens were exposed to a remineralizing solution (60 minutes). The morphological alterations were analyzed by mechanical profilometry (µm) and scanning electron microscopy (SEM). Data were submitted to one-way analysis of variance (ANOVA) and Tukey tests (p < 0.05).

Results

Control and RI groups presented mineral wear and did not significantly differ from each other (p = 0.063). DRI maintained a protective layer preserving the dentin (p < 0.001). After erosive/abrasive cycles, it was observed that in group RI, only 25% of the slabs partially evidenced the presence of the infiltrating, while, in the DRI group, 80% of the slabs presented the treated surface entirely covered by a resin-component layer protecting the dentin surface as observed in SEM images.

Conclusions

The removal of the organic content allows the resin infiltrant to efficiently protect the dentin surface against erosive/abrasive lesions.

Citations

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Acidic/abrasive challenges on simulated non-carious cervical lesions development and morphology
Giovanna C. Denucci, Ian Towle, Cecilia P. Turssi, George J. Eckert, Anderson T. Hara
Archives of Oral Biology.2025; 169: 106120. CrossRef
Physio‐Mechanic and Microscopic Analyses of Bioactive Glass‐Based Resin Infiltrants
Syed Zubairuddin Ahmed, Abdul Samad Khan, Wejdan Waleed Nasser, Methayel Abdulrahman Alrushaid, Zahrah Mohammed Alfaraj, Moayad Mohammed Aljeshi, Asma Tufail Shah, Budi Aslinie Md Sabri, Sultan Akhtar, Mohamed Ibrahim Abu Hassan
Microscopy Research and Technique.2025; 88(2): 595. CrossRef

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Chitosan-induced biomodification on demineralized dentin to improve the adhesive interface: Isabella Rodrigues Ziotti, Vitória Leite Paschoini, Silmara Aparecida Milori Corona, Aline Evangelista Souza-Gabriel; Restor Dent Endod 2022;47(3):e28. Published online June 15, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e28

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Objectives

Metalloproteinase-inhibiting agents, such as chitosan, can prevent collagen degradation in demineralized dental substrates, thereby improving the adhesive interface. This study evaluated the bond strength (BS) and chemical and morphological characterization of the adhesive interface after applying chitosan solution to demineralized dentin.

Materials and Methods

The 80 third molars were selected. Forty teeth underwent caries induction using the pH cycling method. The teeth were divided according to the treatment: distilled water (control) and 2.5% chitosan solution. The surfaces were restored using adhesive and composite resins. Half of the specimens in each group were aged, and the other half underwent immediate analyses. The teeth were sectioned and underwent the microtensile bond strength test (µTBS), and chemical and morphological analyses using energy-dispersive spectroscopy and scanning electron microscopy, respectively. Data analysis was performed using 3-way analysis of variance.

Results

For µTBS, sound dentin was superior to demineralized dentin (p < 0.001), chitosan-treated specimens had higher bond strength than the untreated ones (p < 0.001), and those that underwent immediate analysis had higher values than the aged specimens (p = 0.019). No significant differences were observed in the chemical or morphological compositions.

Conclusions

Chitosan treatment improved bond strength both immediately and after aging, even in demineralized dentin.

Citations

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Push-Out Bond Strength of Different Luting Cements Following Post Space Irrigation with 2% Chitosan: An In Vitro Study
Shimaa Rifaat, Ahmed Rahoma, Hind Muneer Alharbi, Sawsan Jamal Kazim, Shrouq Ali Aljuaid, Basmah Omar Alakloby, Faraz A. Farooqi, Noha Taymour
Prosthesis.2025; 7(1): 18. CrossRef
Recent advances in medical applications of chitosan-based biomaterials
Dinesh Kumar Sharma
International Journal of Polymeric Materials and Polymeric Biomaterials.2024; : 1. CrossRef
Does dentin pretreatment with chitosan improve the bond strength of restorative material? A systematic review and meta-analysis of in vitro studies
Luísa Valente Gotardo Lara Alves, Nathália Mancioppi Cerqueira, Amanda Pelegrin Candemil, André Luis Faria-e-Silva, Manoel Damião Sousa-Neto, Aline Evangelista Souza-Gabriel
International Journal of Adhesion and Adhesives.2024; 128: 103553. CrossRef
Comparative Evaluation of Apical Leakage in Root Canal Obturation Using AH Plus Sealer, Bioceramic Sealer, and Bioceramic Sealer Incorporated With Chitosan Nanoparticles: An In Vitro Study
Sushmita Rane, Varsha Pandit, Sanpreet S Sachdev, Shivani Chauhan, Rishabh Mistry, Barun Kumar
Cureus.2024;[Epub] CrossRef
Aesthetic impact of resin infiltration and its mechanical effect on ceramic bonding for white spot lesions
Jiaen Shu, Yijia Huang, Xueying Ma, Zhonghua Duan, Pei Wu, Sijing Chu, Yuqiong Wu, Yuhua Wang
BMC Oral Health.2024;[Epub] CrossRef
Effect of Incorporating Chitosan to Resin Modified Glass Ionomer Cement on Shear Bond Strength to Dentin (An In vitro Comparative Study)
Aya Tahseen Khudhair, Muna Saleem Khalaf
Journal of International Society of Preventive and Community Dentistry.2024; 14(3): 225. CrossRef
Biomodification of eroded and abraded dentin with epigallocatechin-3-gallate (EGCG)
Bruna Dantas Abreu, Renata Siqueira Scatolin, Silmara Aparecida Milori Corona, Fabiana Almeida Curylofo Zotti
Journal of the Mechanical Behavior of Biomedical Materials.2023; 147: 106158. CrossRef
Chitosan-Based Biomaterials for Tissue Regeneration
Yevgeniy Kim, Zharylkasyn Zharkinbekov, Kamila Raziyeva, Laura Tabyldiyeva, Kamila Berikova, Dias Zhumagul, Kamila Temirkhanova, Arman Saparov
Pharmaceutics.2023; 15(3): 807. CrossRef
Er:YAG laser in selective caries removal and dentin treatment with chitosan: a randomized clinical trial in primary molars
Rai Matheus Carvalho Santos, Renata Siqueira Scatolin, Sérgio Luiz de Souza Salvador, Aline Evangelista Souza-Gabriel, Silmara Aparecida Milori Corona
Lasers in Medical Science.2023;[Epub] CrossRef
Effect of Dentin Surface Pretreatment With Chitosan Nanoparticles on Immediate and Prolonged Shear Bond Strength of Resin Composite: An in Vitro Study
Shaymaa Ali Abdul-Razzaq, Muna Saleem Khalaf
Dental Hypotheses.2023; 14(3): 84. CrossRef
MODERN TRENDS AND PERSPECTIVES OF THE DEVELOPMENT OF ADHESIVE DENTISTRY. INNOVATIVE TECHNIQUES FOR THE APPLICATION OF ADHESIVE SYSTEMS
Oleksandr O. Pompii, Viktor A. Tkachenko, Tetiana M. Kerimova, Elina S. Pompii
Wiadomości Lekarskie.2023; 76(12): 2721. CrossRef

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Is dentin biomodification with collagen cross-linking agents effective for improving dentin adhesion? A systematic review and meta-analysis: Julianne Coelho Silva, Edson Luiz Cetira Filho, Paulo Goberlânio de Barros Silva, Fábio Wildson Gurgel Costa, Vicente de Paulo Aragão Saboia; Restor Dent Endod 2022;47(2):e23. Published online May 6, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e23

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Objectives

The aim of this investigation was to evaluate the effectiveness of collagen cross-linking agents (CCLAs) used in combination with the adhesive technique in restorative procedures.

Materials and Methods

In this systematic review, the authors followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. An electronic search was performed using PubMed, Scopus, Web of Science, Cochrane Library, LILACS, and DOSS, up to October 2020. The gray literature was also researched. Only randomized clinical trials were selected.

Results

The selection process yielded 3 studies from the 838 retrieved. The addition of CCLAs in the retention of restorations increased the number of events. The postoperative sensitivity scores and marginal adaptation scores showed no significant difference between the CCLA and control groups, and the marginal pigmentation scores showed a significant increase in the CCLA group. There were no caries events in any group throughout the evaluation period.

Conclusions

This systematic review showed that there is no clinical efficacy to justify the use of CCLAs in the protocols performed.

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Riboflavin-ultraviolet-A collagen crosslinking treatments in improving dentin bonding and resistance to enzymatic digestion
Yung-Show Chiang, Ping-Ju Chen, Chun-Chan Ting, Yuh-Ling Chen, Shu-Fen Chuang
Journal of Dental Sciences.2025; 20(1): 109. CrossRef
Effect of dentin bio modifications and matrix metalloproteinase activity on bond strength – A systematic review and meta-analysis
D. Agarwal, S. R. Srinidhi, S. D. Aggarwal, P. Ingle, S. Tandon
Endodontics Today.2025; 23(1): 71. CrossRef
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations
Aline Honorato Damázio, Rosanna Tarkany Basting, Enrico Coser Bridi, Fabiana Mantovani Gomes França, Flávia Lucisano Botelho do Amaral, Cecilia Pedroso Turssi, Waldemir Francisco Vieira Junior, Roberta Tarkany Basting
Brazilian Journal of Oral Sciences.2024; 23: e244006. CrossRef
Effect of Collagen Crosslinkers on Dentin Bond Strength of Adhesive Systems: A Systematic Review and Meta-Analysis
Louis Hardan, Umer Daood, Rim Bourgi, Carlos Enrique Cuevas-Suárez, Walter Devoto, Maciej Zarow, Natalia Jakubowicz, Juan Eliezer Zamarripa-Calderón, Mateusz Radwanski, Giovana Orsini, Monika Lukomska-Szymanska
Cells.2022; 11(15): 2417. CrossRef

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Bonding effects of cleaning protocols and time-point of acid etching on dentin impregnated with endodontic sealer: Tatiane Miranda Manzoli, Joissi Ferrari Zaniboni, João Felipe Besegato, Flávia Angélica Guiotti, Andréa Abi Rached Dantas, Milton Carlos Kuga; Restor Dent Endod 2022;47(2):e21. Published online April 6, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e21

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Objectives

This study aimed to investigate the bonding effects of cleaning protocols on dentin impregnated with endodontic sealer residues using ethanol (E) or xylol (X). The effects of dentin acid etching immediately (I) or 7 days (P) after cleaning were also evaluated. For bonding to dentin, universal adhesive (Scotchbond Universal; 3M ESPE) was used. The persistence of sealer residues, hybrid layer formation and microshear bond strength were the performed analysis.

Materials and Methods

One hundred and twenty bovine dentin specimens were allocated into 4 groups (n = 10): G1 (E+I); G2 (X+I); G3 (E+P); and G4 (X+P). The persistence of sealer residues was evaluated by SEM. Confocal laser scanning microscopy images were taken to measure the formed hybrid layer using the Image J program. For microshear bond strength, 4 resin composite cylinders were placed over the dentin after the cleaning protocols. ANOVA followed by Tukey test and Kruskal-Wallis followed by Dunn test were used for parametric and non-parametric data, respectively (α = 5%).

Results

G2 and G4 groups showed a lower persistence of residues (p < 0.05) and thicker hybrid layer than the other groups (p < 0.05). No bond strength differences among all groups were observed (p > 0.05).

Conclusions

Dentin cleaning using xylol, regardless of the time-point of acid etching, provided lower persistence of residues over the surface and thicker hybrid layer. However, the bond strength of the universal adhesive system in etch-and-rinse strategy was not influenced by the cleaning protocols or time-point of acid etching.

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Influence of the Use of a Mixed Solution of Equal Amounts of Amyl Acetate, Acetone, and Ethanol on the Cleaning of Endodontic Sealer Residues on the Bond Strength of the Fiber Post Cementation System: A Laboratory Investigation
Antonia Patricia Oliveira Barros, Ana Paula Aparecida Raimundo Alves Freitas, Frederico Guilherme Otto Kokol, Elizangela Maria Pereira de Souza, Adirson Jorge Junior, Cristiane de Melo Alencar, Marcelo Ferrarezi de Andrade, Milton Carlos Kuga
The Open Dentistry Journal.2024;[Epub] CrossRef
Effects of the application protocol and bonding strategy of the universal adhesive on dentin previously impregnated with bioceramic sealer
Antonia Patricia Oliveira Barros, Joatan Lucas de Sousa Gomes Costa, Jardel Camilo do Carmo Monteiro, Lucas David Galvani, Marcelo Ferrarezi de Andrade, José Roberto Cury Saad, Milton Carlos Kuga
International Journal of Adhesion and Adhesives.2024; 134: 103765. CrossRef
Influência do protocolo de remoção de resíduos de cimentos à base de resina epóxi sobre a interface de adesão com o adesivo universal, utilizado na estratégia condiciona-e-lava
Paulo Firmino Da Costa Neto, Mariana Bena Gelio, Elisângela Maria Pereira De Souza, Jardel Camilo do Carmo Monteiro, Adirson Jorge Júnior, Thais Piragine Leandrin, José Roberto Cury Saad, Milton Carlos Kuga
Cuadernos de Educación y Desarrollo.2023; 15(5): 4802. CrossRef

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Review Article

Deep proximal margin rebuilding with direct esthetic restorations: a systematic review of marginal adaptation and bond strength: Hoda S. Ismail, Ashraf I. Ali, Rabab El. Mehesen, Jelena Juloski, Franklin Garcia-Godoy, Salah H. Mahmoud; Restor Dent Endod 2022;47(2):e15. Published online March 4, 2022; DOI: https://doi.org/10.5395/rde.2022.47.e15

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This review aimed to characterize the effect of direct restorative material types and adhesive protocols on marginal adaptation and the bond strength of the interface between the material and the proximal dentin/cementum. An electronic search of 3 databases (the National Library of Medicine [MEDLINE/PubMed], Scopus, and ScienceDirect) was conducted. Studies were included if they evaluated marginal adaptation or bond strength tests for proximal restorations under the cementoenamel junction. Only 16 studies met the inclusion criteria and were included in this review. These studies presented a high degree of heterogeneity in terms of the materials used and the methodologies and evaluation criteria of each test; therefore, only a descriptive analysis could be conducted. The included studies were individually evaluated for the risk of bias following predetermined criteria. To summarize the results of the included studies, the type of restorative material affected the test results, whereas the use of different adhesive protocols had an insignificant effect on the results. It could be concluded that various categories of resin-based composites could be a suitable choice for clinicians to elevate proximal dentin/cementum margins, rather than the open sandwich technique with resin-modified glass ionomers. Despite challenges in bonding to proximal dentin/cementum margins, different adhesive protocols provided comparable outcomes.

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An In Vitro Evaluation of Novel Bioactive Liner's Effect on Marginal Adaptation of Class II Composite Restorations: A Scanning Electron Microscope Analysis
Girija S Sajjan, Naveena Ponnada, Praveen Dalavai, Madhu Varma Kanumuri, Venkata Karteek Varma Penmatsa, B V Sindhuja
World Journal of Dentistry.2025; 15(9): 749. CrossRef
Effect of Cervical Margin Relocation With Different Injectable Restorative Materials on Fracture Resistance of Molars Received MOD CAD/CAM Onlay Restorations
Basema N. Roshdy, Radwa I. Eltoukhy, Ashraf I. Ali, Salah Hasab Mahmoud
Journal of Esthetic and Restorative Dentistry.2025;[Epub] CrossRef
Short dentin etching with universal adhesives: effect on bond strength and gingival margin adaptation
Hoda Saleh Ismail, Hanan Ahmed Nabil Soliman
BMC Oral Health.2025;[Epub] CrossRef
Awareness and Practice of Deep Margin Elevation among Dental Practitioners in India: A Cross-Sectional Survey
Mythri Padaru, Preethesh Shetty, Namith Rai, Raksha Bhat
Pesquisa Brasileira em Odontopediatria e Clínica Integrada.2025;[Epub] CrossRef
Effect of different restorative systems and aging on marginal adaptation of resin composites to deep proximal margins
Hoda S. Ismail, Ashraf I. Ali
Journal of Esthetic and Restorative Dentistry.2024; 36(2): 346. CrossRef
Management of subgingival proximal defects
Jagruti Mutalikdesai, K. C. Dhaniba, Supriya Choudhary, Promila Verma, Rhythm Bains
Asian Journal of Oral Health and Allied Sciences.2024; 14: 15. CrossRef
Effect of Deep Margin Elevation on the Pulpal and Periodontal Health of Teeth: A Systematic Review
S Srirama, S Jain, B Arul, K Prabakar, V Natanasabapathy
Operative Dentistry.2024; 49(4): 388. CrossRef
Alternative Direct Restorative Materials for Dental Amalgam: A Concise Review Based on an FDI Policy Statement
Gottfried Schmalz, Falk Schwendicke, Reinhard Hickel, Jeffrey A. Platt
International Dental Journal.2024; 74(4): 661. CrossRef
Comparison of the stress distribution in base materials and thicknesses in composite resin restorations
Min-Kwan Jung, Mi-Jeong Jeon, Jae-Hoon Kim, Sung-Ae Son, Jeong-Kil Park, Deog-Gyu Seo
Heliyon.2024; 10(3): e25040. CrossRef
Influence of curing mode and aging on the bonding performance of universal adhesives in coronal and root dentin
Hoda Saleh Ismail, Ashraf Ibrahim Ali, Mohamed Elshirbeny Elawsya
BMC Oral Health.2024;[Epub] CrossRef
CLINICAL ASSESSMENT OF THE EFFECTIVENESS OF ESTHETIC RESTORATION OF ANTERIOR TEETH
Lyudmila Tatintsyan, Minas Poghosyan, Armen Shaginyan, Hovhannes Gevorgyan, Biayna Hoveyan, Tatevik Margaryan, Arsen Kupelyan
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY.2023; : 16. CrossRef
Deep margin elevation—Present status and future directions
Florin Eggmann, Jose M. Ayub, Julián Conejo, Markus B. Blatz
Journal of Esthetic and Restorative Dentistry.2023; 35(1): 26. CrossRef

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Research Articles

Effects of dentin surface preparations on bonding of self-etching adhesives under simulated pulpal pressure: Chantima Siriporananon, Pisol Senawongse, Vanthana Sattabanasuk, Natchalee Srimaneekarn, Hidehiko Sano, Pipop Saikaew; Restor Dent Endod 2022;47(1):e4. Published online December 28, 2021; DOI: https://doi.org/10.5395/rde.2022.47.e4

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Objectives

This study evaluated the effects of different smear layer preparations on the dentin permeability and microtensile bond strength (µTBS) of 2 self-etching adhesives (Clearfil SE Bond [CSE] and Clearfil Tri-S Bond Universal [CTS]) under dynamic pulpal pressure.

Materials and Methods

Human third molars were cut into crown segments. The dentin surfaces were prepared using 4 armamentaria: 600-grit SiC paper, coarse diamond burs, superfine diamond burs, and carbide burs. The pulp chamber of each crown segment was connected to a dynamic intra-pulpal pressure simulation apparatus, and the permeability test was done under a pressure of 15 cmH₂O. The relative permeability (%P) was evaluated on the smear layer-covered and bonded dentin surfaces. The teeth were bonded to either of the adhesives under pulpal pressure simulation, and cut into sticks after 24 hours water storage for the µTBS test. The resin-dentin interface and nanoleakage observations were performed using a scanning electron microscope. Statistical comparisons were done using analysis of variance and post hoc tests.

Results

Only the method of surface preparation had a significant effect on permeability (p < 0.05). The smear layers created by the carbide and superfine diamond burs yielded the lowest permeability. CSE demonstrated a higher µTBS, with these values in the superfine diamond and carbide bur groups being the highest. Microscopic evaluation of the resin-dentin interface revealed nanoleakage in the coarse diamond bur and SiC paper groups for both adhesives.

Conclusions

Superfine diamond and carbide burs can be recommended for dentin preparation with the use of 2-step CSE.

Citations

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The effect of different adhesive strategies and diamond burs on dentin bond strength of universal resin cements
Chavakorn Atsavathavornset, Pipop Saikaew, Choltacha Harnirattisai, Hidehiko Sano
Clinical Oral Investigations.2025;[Epub] CrossRef
Universal adhesive systems in dentistry: A narrative review
Svetlana N. Razumova, Anzhela S. Brago, Oxana R. Ruda, Zoya A. Guryeva, Elvira V. Adzhieva
Russian Journal of Dentistry.2024; 28(5): 512. CrossRef
Delayed light activation of resin composite affects the bond strength of adhesives under dynamic simulated pulpal pressure
Nattaporn Sukprasert, Choltacha Harnirattisai, Pisol Senawongse, Hidehiko Sano, Pipop Saikaew
Clinical Oral Investigations.2022; 26(11): 6743. CrossRef

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Comparative analysis of bond strength to root dentin and compression of bioceramic cements used in regenerative endodontic procedures: Maykely Naara Morais Rodrigues, Kely Firmino Bruno, Ana Helena Gonçalves de Alencar, Julyana Dumas Santos Silva, Patrícia Correia de Siqueira, Daniel de Almeida Decurcio, Carlos Estrela; Restor Dent Endod 2021;46(4):e59. Published online November 9, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e59

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Objectives

This study compared the Biodentine, MTA Repair HP, and Bio-C Repair bioceramics in terms of bond strength to dentin, failure mode, and compression.

Materials and Methods

Fifty-four slices obtained from the cervical third of 18 single-rooted human mandibular premolars were randomly distributed (n = 18). After insertion of the bioceramic materials, the push-out test was performed. The failure mode was analyzed using stereomicroscopy. Another set of cylindrically-shaped bioceramic samples (n = 10) was prepared for compressive strength testing. The normality of data distribution was analyzed using the Shapiro-Wilk test. The Kruskal-Wallis and Friedman tests were used for the push-out test data, while compressive strength was analyzed with analysis of variance and the Tukey test, considering a significance level of 0.05.

Results

Biodentine presented a higher median bond strength value (14.79 MPa) than MTA Repair HP (8.84 MPa) and Bio-C Repair (3.48 MPa), with a significant difference only between Biodentine and Bio-C Repair. In the Biodentine group, the most frequent failure mode was mixed (61%), while in the MTA Repair HP and Bio-C Repair groups, it was adhesive (94% and 72%, respectively). Biodentine showed greater resistance to compression (29.59 ± 8.47 MPa) than MTA Repair HP (18.68 ± 7.40 MPa) and Bio-C Repair (19.96 ± 3.96 MPa) (p < 0.05).

Conclusions

Biodentine showed greater compressive strength than MTA Repair HP and Bio-C Repair, and greater bond strength than Bio-C Repair. The most frequent failure mode of Biodentine was mixed, while that of MTA Repair HP and Bio-C Repair was adhesive.

Citations

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Comparación de la resistencia compresiva entre el Agregado Trióxido Mineral y BiodentineTM en perforaciones de furca de molares inferiores permanentes
Jheymy Gerardo Huatuco-Granda, John Paul Torres-Navarro, Rosa Josefina Roncal-Espinoza
Revista Facultad de Odontología.2024;[Epub] CrossRef
Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis
Gabriela Leite de Souza, Gabrielle Alves Nunes Freitas, Maria Tereza Hordones Ribeiro, Nelly Xiomara Alvarado Lemus, Carlos José Soares, Camilla Christian Gomes Moura
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
Evaluation the Marginal Adaptation for the Bio C Repair and Other Root end Filling Material by Using Scanning Electron Microscope (A Comparative In Vitro Study)
Fatimah HAMADHİ, Zainab M.
Cumhuriyet Dental Journal.2023; 26(3): 261. CrossRef
Dentin Bond Strength of Calcium Silicate-Based Materials: A Systematic Review of In Vitro Studies
Natalia Radulica, José Luis Sanz, Adrián Lozano
Applied Sciences.2023; 14(1): 104. CrossRef
Evaluation Of The Push-out Bond Strength Of The Bio-C Repair And Compare It With The Mineral Trioxide Aggregate And Amalgam When Used As Root-end Filling Material
Fatimah R. Hammadi, Zainab M Abdul-Ameer
Dental Hypotheses.2023; 14(2): 62. CrossRef
Effect of different root canal irrigants on push-out bond strength of two novel root-end filling materials
Nada Omar, Rasha M. Abdelraouf, Tamer M. Hamdy
BMC Oral Health.2023;[Epub] CrossRef
Effect of irrigation systems on the bond strength of calcium-silicate-based cement used as pulp barrier in regenerative endodontic treatment
Cihan Hascizmeci, Burak Buldur
Journal of Adhesion Science and Technology.2023; 37(23): 3393. CrossRef

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Adhesive systems applied to dentin substrate under electric current: systematic review: Carolina Menezes Maciel, Tatiane Cristina Vieira Souto, Bárbara de Almeida Pinto, Laís Regiane Silva-Concilio, Kusai Baroudi, Rafael Pino Vitti; Restor Dent Endod 2021;46(4):e55. Published online November 5, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e55

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Objectives

The purpose of this systematic review was to collect and discuss the technique of adhesive systems application on dentin substrate under electric current.

Materials and Methods

The first search strategy was based on data available at PubMed, LILACS, Scielo, Scopus, and Cochrane Library, using a combination of descriptors such as “dentin bond agents OR adhesive system AND electric current OR electrobond” or “dentin bonding agents OR dentin bonding agent application OR adhesive system AND electric current OR electrobond”, with no limit regarding the publication year. The second search strategy was based on the articles' references found previously. An additional search strategy was applied that concerned the proposed theme in the SBU-UNICAMP (Unicamp's Library System Institutional Repository).

Results

Twelve studies published between 2006 and 2020 were found. The analyses of the selected studies showed that the use of electric current during adhesive systems application on dentin, whether conventional or self-conditioning, increases resinous monomer infiltration in the dentin substrate, which improves the hybridization processes and the bond strength of the restorative material to dentin.

Conclusions

Despite the favorable results related to the use of this technique, there is still no specific protocol for the application of adhesive systems under electric current.

Citations

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Iontophoresis effects of two-step self-etch and total-etch systems on dentin permeability and sealing of composite restoration under simulated pulpal pressure
Orapin Ajcharanukul, Peeraya Santikulluk, Palat Sasingha, Sirithorn Sabpawat, Kanokporn Sukyanan
BMC Oral Health.2022;[Epub] CrossRef

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Biomineralization of three calcium silicate-based cements after implantation in rat subcutaneous tissue: Ranjdar Mahmood Talabani, Balkees Taha Garib, Reza Masaeli, Kavosh Zandsalimi, Farinaz Ketabat; Restor Dent Endod 2021;46(1):e1. Published online December 2, 2020; DOI: https://doi.org/10.5395/rde.2021.46.e1

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Objectives

The aim of this study was to evaluate the dystrophic mineralization deposits from 3 calcium silicate-based cements (Micro-Mega mineral trioxide aggregate [MM-MTA], Biodentine [BD], and EndoSequence Root Repair Material [ESRRM] putty) over time after subcutaneous implantation into rats.

Materials and Methods

Forty-five silicon tubes containing the tested materials and 15 empty tubes (serving as a control group) were subcutaneously implanted into the backs of 15 Wistar rats. At 1, 4, and 8 weeks after implantation, the animals were euthanized (n = 5 animals/group), and the silicon tubes were removed with the surrounding tissues. Histopathological tissue sections were stained with von Kossa stain to assess mineralization. Scanning electron microscopy and energy-dispersive X-ray spectroscopy (SEM/EDX) were also used to assess the chemical components of the surface precipitates deposited on the implant and the pattern of calcium and phosphorus distribution at the material-tissue interface. The calcium-to-phosphorus ratios were compared using the non-parametric Kruskal-Wallis test at a significance level of 5%.

Results

The von Kossa staining showed that both BD and ESRRM putty induced mineralization starting at week 1; this mineralization increased further until the end of the study. In contrast, MM-MTA induced dystrophic calcification later, from 4 weeks onward. SEM/EDX showed no statistically significant differences in the calcium- and phosphorus-rich areas among the 3 materials at any time point (p > 0.05).

Conclusions

After subcutaneous implantation, biomineralization of the 3-calcium silicate-based cements started early and increased over time, and all 3 tested cements generated calcium- and phosphorus-containing surface precipitates.

Citations

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Antibacterial, biocompatible, and mineralization‐inducing properties of calcium silicate‐based cements
Taimy Cruz Hondares, Xiaoxiao Hao, Yanfang Zhao, Yuyin Lin, Dobrawa Napierala, Janice G. Jackson, Ping Zhang
International Journal of Paediatric Dentistry.2024; 34(6): 843. CrossRef
Bioactive potential of Bio‐C Pulpo is evidenced by presence of birefringent calcite and osteocalcin immunoexpression in the rat subcutaneous tissue
Marcela Borsatto Queiroz, Rafaela Nanami Handa Inada, Camila Soares Lopes, Juliane Maria Guerreiro‐Tanomaru, Estela Sasso‐Cerri, Mário Tanomaru‐Filho, Paulo Sérgio Cerri
Journal of Biomedical Materials Research Part B: Applied Biomaterials.2022; 110(10): 2369. CrossRef

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Effect of post space preparation drills on the incidence of root dentin defects: Thaíse Ayres Bezerra Zuli, Orlando Aguirre Guedes, Gislaine Figueiredo Zarza Arguello Gonçalves, Aurélio Rosa da Silva Júnior, Álvaro Henrique Borges, Andreza Maria Fábio Aranha; Restor Dent Endod 2020;45(4):e53. Published online October 16, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e53

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Objectives

This study investigated the incidence of root dentin defects after the use of different post space preparation (PSP) drills.

Materials and Methods

Seventy-two bovine incisors were selected and obtained 14-mm-long root sections. Twelve roots served as controls with no intervention (G1). The 60 root canals remaining were instrumented using the crown-down technique with the ProTaper Next system and obturated using the lateral condensation technique. Specimens were randomly distributed into 5 groups (n = 12) according to the operative steps performed: G2, root canal instrumentation and filling (I+F); G3, I+F and PSP with Gates-Glidden drills; G4, I+F and PSP with Largo-Peeso reamers; G5, I+F and PSP with Exacto drill; and G6, I+F and PSP with WhitePost drill. Roots were sectioned at 3, 6, 9, and 12 mm from the apex, and digital images were captured. The presence of root dentin defects was recorded. Data were analyzed by the χ² test, with p < 0.05 considered to indicate statistical significance.

Results

Root dentin defects were observed in 39.6% of the root sections. No defects were observed in G1. G5 had significantly more cracks and craze lines than G1, G2, and G3 (p < 0.05), and more fractures than G1, G2, G3, and G4 (p < 0.05). When all root sections were analyzed together, significantly more defects were observed at the 12-mm level than at the 3-mm level (p < 0.05).

Conclusions

PSP drills caused defects in the root dentin. Gates-Glidden drills caused fewer root defects than Largo-Peeso reamers and Exacto drills.

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Evaluation of dentinal crack formation during post space preparation using different fiber post systems with micro-computed tomography
Ayşe Nur Kuşuçar, Damla Kırıcı
BMC Oral Health.2025;[Epub] CrossRef
Selecting drill size for post space preparation based on final endodontic radiographs: An in vitro study
Farzaneh Farid, Julfikar Haider, Marjan Sadeghpour Shahab, Nika Rezaeikalantari
Technology and Health Care.2024; 32(4): 2575. CrossRef
Cone Beam Computed Tomography Analysis of Post Space in Bifurcated Premolars Using ParaPost and Peeso Reamer Drills
Abdulaziz Saleh Alqahtani, Omar Nasser Almonabhi, Abdulmajeed Moh. Almutairi, Reem R. Alnatsha
The Open Dentistry Journal.2024;[Epub] CrossRef
A Comparative Evaluation of Real-Time Guided Dynamic Navigation and Conventional Techniques for Post Space Preparation During Post Endodontic Management: An In Vitro Study
Sherifa Shervani, Sihivahanan Dhanasekaran, Vijay Venkatesh
Cureus.2024;[Epub] CrossRef
The effect of ultrasonic vibration protocols for cast post removal on the incidence of root dentin defects
Giulliano C. Serpa, Orlando A. Guedes, Neurinelma S. S. Freitas, Julio A. Silva, Carlos Estrela, Daniel A. Decurcio
Journal of Oral Science.2023; 65(3): 190. CrossRef

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Physicochemical properties, cytotoxicity and penetration into dentinal tubules of sodium hypochlorite with and without surfactants: Hernán Coaguila-Llerena, Isadora Barbieri, Mário Tanomaru-Filho, Renato de Toledo Leonardo, Ana Paula Ramos, Gisele Faria; Restor Dent Endod 2020;45(4):e47. Published online September 10, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e47

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Objectives

The aim of this study was to assess the physicochemical properties, cytotoxicity and penetration into dentinal tubules of ChlorCid™ Surf (3% sodium hypochlorite [NaOCl] with surfactant) in comparison to ChlorCid™ (3% NaOCl without surfactant).

Materials and Methods

The physicochemical properties evaluated were pH, surface tension, free available chlorine (FAC) and contact angle. Cytotoxicity was evaluated in L929 fibroblasts exposed to the solutions by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide and neutral red assays. Assessment of penetration into dentinal tubules was performed by staining single-rooted permanent human teeth with crystal violet (n = 9), which were irrigated with the solutions and analyzed in cervical, middle and apical segments. Data were analyzed by one-way analysis of variance (ANOVA) and Tukey's post-test, 2-way ANOVA and Bonferroni's post-test or t-test (α = 0.05).

Results

ChlorCid™ Surf and ChlorCid™ FAC values were close to those indicated by the manufacturer. ChlorCid™ Surf showed lower surface tension and contact angle on dentin, and higher pH than ChlorCid™ (p < 0.05). The penetration of ChlorCid™ Surf was higher in cervical and middle segments, compared with ChlorCid™ (p < 0.05). There was no difference in irrigant cytotoxicity (p > 0.05).

Conclusions

ChlorCid™ Surf showed lower surface tension, lower contact angle on root canal dentin, higher penetration into dentinal tubules and more alkaline pH, compared with ChlorCid™. However, both solutions showed similar cytotoxicity and FAC content.

Citations

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Hernán Coaguila-Llerena, Luana Raphael da Silva, Gisele Faria
Heliyon.2024; 10(1): e23060. CrossRef
Amelioration in the sodium hypochlorite as root canal irrigant – A review
Preety Sehrawat
International Dental Journal of Student's Research.2024; 12(2): 65. CrossRef
Sonic-assisted antibacterial photodynamic therapy: a strategy for enhancing lateral canal disinfection
Yanhuang Wang, Lishan Lei, Jing Huang, Zhiyu Cai, Xiaojing Huang
BMC Oral Health.2024;[Epub] CrossRef
A Comparative Evaluation of Contact Angle and Depth of Penetration of Sodium Hypochlorite With Various Surfactants: An In Vitro Study
Shubhashini N, Krithika D, Akhilesh Gowda , Shruthi Nagaraja , Rhea S Mathew, Nivaskumar G A, Vinaychandra R
Cureus.2024;[Epub] CrossRef
Antibacterial efficacy of silver nanoparticles, sodium hypochlorite, chlorhexidine, and hypochlorous acid on dentinal surfaces infected with Enterococcus faecalis
Aysenur Oncu, Berkan Celikten, Betül Aydın, Gulin Amasya, Erkan Tuncay, Gamze Guney Eskiler, Leyla Açık, Fatma Semra Sevimay
Microscopy Research and Technique.2024; 87(9): 2094. CrossRef
Advances in the Role of Sodium Hypochlorite Irrigant in Chemical Preparation of Root Canal Treatment
Chen Cai, Xuan Chen, Yang Li, Qianzhou Jiang, Yeliz Guven
BioMed Research International.2023;[Epub] CrossRef
Effect of sodium hypochlorite-based formulations on the adhesion interface after fiber post cementation
Joatan Lucas de Sousa Gomes COSTA, Tatiane Miranda MANZOLI, João Felipe BESEGATO, Joissi Ferrari ZANIBONI, Eliane Cristina Gulin DE OLIVEIRA, Lucas David GALVANI, Andréa Abi Rached DANTAS, Luis Geraldo VAZ, Milton Carlos KUGA
Dental Materials Journal.2023; 42(6): 878. CrossRef
Physicochemical properties and penetration into dentinal tubules of calcium hypochlorite with surfactants
Hernán Coaguila-Llerena, Julia da Silva Toledo, Ana Paula Ramos, Gisele Faria
Brazilian Dental Journal.2022; 33(2): 1. CrossRef

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Invited Review Article

The effect of root canal irrigants on dentin: a focused review: Priti Pragati Rath, Cynthia Kar Yung Yiu, Jukka Pekka Matinlinna, Anil Kishen, Prasanna Neelakantan; Restor Dent Endod 2020;45(3):e39. Published online June 30, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e39

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Despite the vast literature on the effects of root canal irrigants on the dentin characteristics, the precise effects of clinically relevant irrigation sequences remain unclear. In this review, we systematically dissect the role of different sequential irrigation approaches that are used in clinical endodontics. Using a systematic search strategy, we attempt to answer the question: ‘Which irrigating sequence has the most deleterious effects on dentin structure and properties?’ The effect of irrigants on the dentin composition and mechanical properties have been reviewed. A wide variety of concentrations, duration and techniques have been employed to characterize the effects of chemicals on dentin properties, thus making it impossible to draw guidelines or recommendations of irrigant sequences to be followed clinically. It was apparent that all the studied irrigation sequences potentially result in some deleterious effects on dentin such as decrease in the flexural strength, microhardness, modulus of elasticity and inorganic content and organic-inorganic ratio of the dentin. However, the literature still lacks comprehensive investigations to compare the deleterious effect of different irrigation sequences, using a wide variety of qualitative and quantitative methods. Such investigations are essential to make clinical recommendations and strategize efforts to minimize chemically-induced damage to dentin characteristics.

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Research Article

Bonding of a resin-modified glass ionomer cement to dentin using universal adhesives: Muhittin Ugurlu; Restor Dent Endod 2020;45(3):e36. Published online June 15, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e36

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Objectives

This study aims to assess the effect of universal adhesives pretreatment on the bond strength of resin-modified glass ionomer cement to dentin.

Materials and Methods

Fifty caries-free human third molars were employed. The teeth were randomly assigned into five groups (n = 10) based on dentin surface pretreatments: Single Bond Universal (3M Oral Care), Gluma Bond Universal (Heraeus Kulzer), Prime&Bond Elect (Dentsply), Cavity Conditioner (GC) and control (no surface treatment). After Fuji II LC (GC) was bonded to the dentin surfaces, the specimens were stored for 7 days at 37°C. The specimens were segmented into microspecimens, and the microspecimens were subjugated to microtensile bond strength testing (1.0 mm/min). The modes of failure analyzed using a stereomicroscope and scanning electron microscopy. Data were statistically analyzed with one-way analysis of variance and Duncan tests (p = 0.05).

Results

The surface pretreatments with the universal adhesives and conditioner increased the bond strength of Fuji II LC to dentin (p < 0.05). Single Bond Universal and Gluma Bond Universal provided higher bond strength to Fuji II LC than Cavity Conditioner (p < 0.05). The bond strengths obtained from Prime&Bond Elect and Cavity Conditioner were not statistically different (p > 0.05).

Conclusions

The universal adhesives and polyacrylic acid conditioner could increase the bond strength of resin-modified glass ionomer cement (RMGIC) to dentin. The use of universal adhesives before the application of RMGIC may be more beneficial in improving bond strength.

Citations

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Review Article

Inhibition of matrix metalloproteinases: a troubleshooting for dentin adhesion: Izadora Quintela Souza de Moraes, Ticiano Gomes do Nascimento, Antonio Thomás da Silva, Lilian Maria Santos Silva de Lira, Abhishek Parolia, Isabel Cristina Celerino de Moraes Porto; Restor Dent Endod 2020;45(3):e31. Published online May 22, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e31

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Matrix metalloproteinases (MMPs) are enzymes that can degrade collagen in hybrid layer and reduce the longevity of adhesive restorations. As scientific understanding of the MMPs has advanced, useful strategies focusing on preventing these enzymes' actions by MMP inhibitors have quickly developed in many medical fields. However, in restorative dentistry, it is still not well established. This paper is an overview of the strategies to inhibit MMPs that can achieve a long-lasting material-tooth adhesion. Literature search was performed comprehensively using the electronic databases: PubMed, ScienceDirect and Scopus including articles from May 2007 to December 2019 and the main search terms were “matrix metalloproteinases”, “collagen”, and “dentin” and “hybrid layer”. MMPs typical structure consists of several distinct domains. MMP inhibitors can be divided into 2 main groups: synthetic (synthetic-peptides, non-peptide molecules and compounds, tetracyclines, metallic ions, and others) and natural bioactive inhibitors mainly flavonoids. Selective inhibitors of MMPs promise to be the future for specific targeting of preventing dentin proteolysis. The knowledge about MMPs functionality should be considered to synthesize drugs capable to efficiently and selectively block MMPs chemical routes targeting their inactivation in order to overcome the current limitations of the therapeutic use of MMPs inhibitors, i.e., easy clinical application and long-lasting effect.

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Rim Bourgi, Umer Daood, Mohammed Nadeem Bijle, Amr Fawzy, Maroun Ghaleb, Louis Hardan
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Research Article

Dentin moisture conditions strongly influence its interactions with bioactive root canal sealers: Esin Ozlek, Hüseyin Gündüz, Elif Akkol, Prasanna Neelakantan; Restor Dent Endod 2020;45(2):e24. Published online March 24, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e24

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Objectives

It is known that bioactive materials interact with the dentin to undergo biomineralization. The exact role of moisture in this interaction is unknown. Here, we investigate the effects of dentin moisture conditions on the dislocation resistance of two bioactive root canal sealers (MTA Fillapex [Angelus Solucoes Odontologicas] and GuttaFlow BioSeal [Colténe/Whaledent AG]) at 3 weeks and 3 months after obturation.

Materials and Methods

Mandibular premolars (n = 120) were prepared and randomly divided into 3 groups based on the dentin condition: group 1, dry dentin; group 2, moist dentin; group 3, wet dentin. Each group was divided into 2 subgroups for root canal filling: MTA Fillapex and GuttaFlow BioSeal. Dislocation resistance was evaluated by measuring the push-out bond strength at 3 weeks and 3 months. Failure modes were examined under a stereomicroscope. Data were statistically analyzed by Kruskal-Wallis test with a significance level of 5%.

Results

Moist dentin resulted in higher bond strength values for both materials at both time points. This was significantly higher than wet and dry dentin for both the sealers at the 3 months (p < 0.05), while at 3 weeks it was significant only for GuttaFlow Bioseal. The different moisture conditions demonstrated similar trends in their effects on the dislocation resistance of the 2 root canal sealers.

Conclusions

The dentin moisture conditions had a significant impact on its interaction with the bioactive materials tested. Maintaining moist dentin, but not dry or wet dentin, may be advantageous before the filling root canals with bioactive sealers.

Citations

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M. Bilal, S. Pasha, S. Kumar, S. Arif, S. Taj, A. Saleem
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Nawal Atiya Al-Sabawi, Sawsan Hameed Al-Jubori
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Bokyung Shin, Ji-Hwan Seo, Wonjung Kim, Yu Jin Ahn, Ho-Young Kim, Won-Jun Shon
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Yoon-Joo Lee, Kyung-Mo Cho, Se-Hee Park, Yoon Lee, Jin-Woo Kim
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Tobias Hahn, David W. Christofzik, Karim Fawzy El-Sayed, Sandra Freitag-Wolf, Jonas Conrad, Christian Graetz, Birte Größner-Schreiber, Christof Dörfer, Artak Heboyan
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Ahmadreza Sarrafan, Ali Soleymani, Tasnim Bagheri Chenari, Seyedali Seyedmajidi
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Gizem Kadı, Esin Özlek, Yousef Saed
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Ana C P Janini, Lauter E Pelepenko, Brenda P F A Gomes, Marina A Marciano
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Materials.2020; 13(19): 4389. CrossRef

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Review Article

Age-dependent root canal instrumentation techniques: a comprehensive narrative review: Michael Solomonov, Hyeon-Cheol Kim, Avi Hadad, Dan Henry Levy, Joe Ben Itzhak, Oleg Levinson, Hadas Azizi; Restor Dent Endod 2020;45(2):e21. Published online March 4, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e21

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The aim of this article was to review age-dependent clinical recommendations for appropriate root canal instrumentation techniques. A comprehensive narrative review of canal morphology, the structural characteristics of dentin, and endodontic outcomes at different ages was undertaken instead of a systematic review. An electronic literature search was carried out, including the Medline (Ovid), PubMed, and Web of Science databases. The searches used controlled vocabulary and free-text terms, as follows: ‘age-related root canal treatment,’ ‘age-related instrumentation,’ ‘age-related chemo-mechanical preparation,’ ‘age-related endodontic clinical recommendations,’ ‘root canal instrumentation at different ages,’ ‘geriatric root canal treatment,’ and ‘pediatric root canal treatment.’ Due to the lack of literature with practical age-based clinical recommendations for an appropriate root canal instrumentation technique, a narrative review was conducted to suggest a clinical algorithm for choosing the most appropriate instrumentation technique during root canal treatment. Based on the evidence found through the narrative review, an age-related clinical algorithm for choosing appropriate instrumentation during root canal treatment was proposed. Age affects the morphology of the root canal system and the structural characteristics of dentin. The clinician’s awareness of root canal morphology and dentin characteristics can influence the choice of instruments for root canal treatment.

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Cross-Sectional Analysis of the Challenges Faced by Undergraduate Dental Students During Root Canal Treatment (RCT) and the Oral Health-Related Quality of Life in Patients After RCT
Mubashir Baig Mirza, Abdullah Bajran Almuteb, Abdulaziz Tariq Alsheddi, Qamar Hashem, Mohammed Ali Abuelqomsan, Ahmed AlMokhatieb, Shahad AlBader, Abdullah AlShehri
Medicina.2025; 61(2): 215. CrossRef
Assessment of Anatomical Dentin Thickness in Mandibular First Molar: An In Vivo Cone‐Beam Computed Tomographic Study
Sahil Choudhari, Kavalipurapu Venkata Teja, Sindhu Ramesh, Jerry Jose, Mariangela Cernera, Parisa Soltani, Emmanuel João Nogueira Leal da Silva, Gianrico Spagnuolo, Ricardo Danil Guiraldo
International Journal of Dentistry.2024;[Epub] CrossRef
Oral Health Concerns of the ‘Sunset Age’
Pradnya V. Kakodkar, Amandeep Kaur, Shivasakthy Manivasakan, Sounyala Rayannavar, Revati Deshmukh, Smita Athavale
Journal of Medical Evidence.2023; 4(2): 141. CrossRef
Root canal treatment of a six-canal first mandibular molar with extensive periapical lesion: A case report
Xin Li, Shuyu Sun, Tengyi Zheng
Medicine.2023; 102(30): e34336. CrossRef
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Laura Iosif, Bogdan Dimitriu, Dan Florin Niţoi, Oana Amza
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Mechanisms of age-related changes in the morphology of the pulp system of the first lower molars
N.B. Petrukhina, O.A. Zorina, V.A. Venediktova
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Research Articles

Comparative evaluation of the bond strength of self-adhering and bulk-fill flowable composites to MTA Plus, Dycal, Biodentine, and TheraCal: an in vitro study: Aakrati Raina, Asheesh Sawhny, Saurav Paul, Sridevi Nandamuri; Restor Dent Endod 2020;45(1):e10. Published online January 8, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e10

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Objectives

This study aimed to compare the shear bond strength (SBS) of a self-adhering flowable composite (Dyad Flow) and a bulk-fill flowable composite (Smart Dentin Replacement [SDR]) to several pulp-capping materials, including MTA Plus, Dycal, Biodentine, and TheraCal.

Materials and Methods

Eighty acrylic blocks with 2-mm-deep central holes that were 4 mm in diameter were prepared and divided into 2 groups (n = 40 each) according to the composite used (Dyad Flow or SDR). They were further divided into 4 sub-groups (n = 10 each) according to the pulp-capping agent used. SBS was tested using a universal testing machine at a crosshead speed of 1 mm/min. Data were analyzed using 2-way analysis of variance. A p value of < 0.05 was considered to indicate statistical significance.

Results

A statistically significant difference (p = 0.040) was found between Dyad Flow and SDR in terms of bond strength to MTA Plus, Dycal, Biodentine, and TheraCal.

Conclusions

Among the 8 sub-groups, the combination of TheraCal and SDR exhibited the highest SBS.

Citations

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Hygroscopic bioactive light-cured composite promoting dentine bridge formation
Yunzi Long, Guibin Huang, Siyi Liu, Liju Xu, Ailing Li, Dong Qiu, Yanmei Dong
Regenerative Biomaterials.2024;[Epub] CrossRef
Comparative evaluation of shear bond strength and modes of failure of five different reinforced glass ionomer restorative cements to TheraCal LC: An in vitro study
Kalyani Gajanan Umale, Vandana Jaykumar Gade, Ambar W. Raut
Journal of Conservative Dentistry and Endodontics.2024; 27(2): 200. CrossRef
Evaluation of the Effect of Chitosan-Based Irrigation Solutions on the Bond Strength of Mineral Trioxide Aggregate to Bulk-Fill Composite
Arzu Şahin Mantı, Bağdagül Helvacıoğlu Kıvanç
Journal of Functional Biomaterials.2024; 15(12): 370. CrossRef
Radiopacity evaluations of the novel calcium-silicate and glass-Ionomer-based materials
Yeşim Şeşen Uslu, Elif Çelebi, Meriç Berkman
Journal of Health Sciences and Medicine.2024; 7(2): 192. CrossRef
Effect of Er Cr YSGG laser etching procedure on the bond strength of different calcium silicate cements
Yesim Sesen Uslu, Hakan Yasin Gönder, Pinar Sesen, Gizem Gunduz Bektaş
Lasers in Dental Science.2024;[Epub] CrossRef
The micro‐shear bond strength of new endodontic tricalcium silicate‐based putty: An in vitro study
Merve Yeniçeri Özata, Seda Falakaloğlu, Gianluca Plotino, Özkan Adıgüzel
Australian Endodontic Journal.2023; 49(1): 124. CrossRef
Analysis of the bond strength between conventional, putty or resin‐modified calcium silicate cement and bulk fill composites
İ Ipek, B Karaağaç Eskibağlar, Ş Yildiz, O Ataş, M Ünal
Australian Dental Journal.2023; 68(4): 265. CrossRef
Effect of Different Adhesive Strategies on the Microshear Bond Strength of Calcium-Silicate-Based Materials
Aliye Tuğçe Gürcan, Soner Şişmanoğlu, Görkem Sengez
Journal of Advanced Oral Research.2022; 13(2): 191. CrossRef
BULK FİLL KOMPOZİT REZİN RESTORATİF MATERYALLER
Merve NEZİR, Suat ÖZCAN
Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi.2022; : 1. CrossRef
Effect of Bioinductive Cavity Liners on Shear Bond Strength of Dental Composite to Dentin
Saba Tohidkhah, Elham Ahmadi, Mahdi Abbasi, Reza Morvaridi Farimani, Ladan Ranjbar Omrani, Victor Feitosa
BioMed Research International.2022;[Epub] CrossRef
Bond Strength of Adhesive Systems to Calcium Silicate-Based Materials: A Systematic Review and Meta-Analysis of In Vitro Studies
Louis Hardan, Davide Mancino, Rim Bourgi, Alejandra Alvarado-Orozco, Laura Emma Rodríguez-Vilchis, Abigailt Flores-Ledesma, Carlos Enrique Cuevas-Suárez, Monika Lukomska-Szymanska, Ammar Eid, Maya-Line Danhache, Maryline Minoux, Youssef Haïkel, Naji Kharo
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How do imaging protocols affect the assessment of root-end fillings?
Fernanda Ferrari Esteves Torres, Reinhilde Jacobs, Mostafa EzEldeen, Karla de Faria-Vasconcelos, Juliane Maria Guerreiro-Tanomaru, Bernardo Camargo dos Santos, Mário Tanomaru-Filho
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Evaluation of Shear Bond Strength of Resin-Based Composites to Biodentine with Three Types of Seventh-Generation Bonding Agents: An In Vitro Study
Huda Abbas Abdullah, Zahraa Abdulaali Al-Ibraheemi, Zanbaq Azeez Hanoon, Julfikar Haider, Boonlert Kukiattrakoon
International Journal of Dentistry.2022; 2022: 1. CrossRef
Evaluation of the Bond Strength of Different Pulp Capping Materials to Dental Adhesive Systems: An In Vitro Study
Sema Yazici Akbiyik, Elif Pınar Bakir, S¸eyhmus Bakir
Journal of Advanced Oral Research.2021; 12(2): 286. CrossRef
Differential Gene Expression Changes in Human Primary Dental Pulp Cells Treated with Biodentine and TheraCal LC Compared to MTA
Ok Hyung Nam, Ho Sun Lee, Jae-Hwan Kim, Yong Kwon Chae, Seoung-Jin Hong, Sang Wook Kang, Hyo-Seol Lee, Sung Chul Choi, Young Kim
Biomedicines.2020; 8(11): 445. CrossRef

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A micro-computed tomography evaluation of voids using calcium silicate-based materials in teeth with simulated internal root resorption: Vildan Tek, Sevinç Aktemur Türker; Restor Dent Endod 2020;45(1):e5. Published online November 29, 2019; DOI: https://doi.org/10.5395/rde.2020.45.e5

Abstract PDF PubReader ePub

Objectives

The obturation quality of MTA, Biodentine, Total Fill BC root canal sealer (RCS), and warm gutta-percha (WGP) in teeth with simulated internal root resorption (IRR) was evaluated by using micro-computed tomography.

Materials and Methods

Standardized IRR cavities were created using 40 extracted maxillary central incisor teeth and randomly assigned into 4 groups (n = 10). IRR cavities were filled with MTA, Biodentine, Total Fill BC RCS (bulk-fill form) and WGP + Total Fill BC RCS. Percentage of voids between resorptive cavity walls and obturation material (external void), and inside the filling materials (internal voids) were measured.

Results

Total Fill BC sealer in the bulk-fill form presented significantly highest values of external and internal void percentages (p < 0.05). Biodentine showed a significantly lowest external void percentage (p < 0.05). WGP + Total Fill BC RCS presented significantly lower values of internal void percentages than all groups (p < 0.05), except Biodentine (p > 0.05).

Conclusion

None of the filling materials were created void-free obturation in resorption cavities. Biodentine may favor its application in teeth with IRR over Angelus MTA and bulk-fill form of Total Fill BC.

Citations

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Evaluation of Different Techniques and Materials for Filling in 3-dimensional Printed Teeth Replicas with Perforating Internal Resorption by Means of Micro–Computed Tomography
Angelo J.S. Torres-Carrillo, Helena C. Assis, Rodrigo E. Salazar-Gamarra, Leonardo Moreira Teodosio, Alice C. Silva-Sousa, Jardel F. Mazzi-Chaves, Priscila B. Ferreira-Soares, Manoel D. Sousa-Neto, Fabiane C. Lopes-Olhê
Journal of Endodontics.2024; 50(2): 205. CrossRef
Three-Dimensional Measurement of Obturation Quality of Bioceramic Materials in Filling Artificial Internal Root Resorption Cavities Using Different Obturation Techniques: An In Vitro Comparative Study
Ammar M. Sharki, Ahmed H. Ali
Journal of Endodontics.2024; 50(7): 997. CrossRef
Evaluation of calcium hydroxide root canal filling materials by cone beam computed tomography and three-dimensional modeling
Asel Usdat Ozturk, Ekin Dogan, Venus Seyedoskuyi, Berk Senguler, Asli Topaloglu-Ak
Folia Medica.2024; 66(2): 250. CrossRef
Clinical applications of calcium silicate‐based materials: a narrative review
S Küçükkaya Eren
Australian Dental Journal.2023;[Epub] CrossRef
A critical analysis of research methods and experimental models to study root canal fillings
Gustavo De‐Deus, Erick Miranda Souza, Emmanuel João Nogueira Leal Silva, Felipe Gonçalves Belladonna, Marco Simões‐Carvalho, Daniele Moreira Cavalcante, Marco Aurélio Versiani
International Endodontic Journal.2022; 55(S2): 384. CrossRef
An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy
Fateme Eskandari, Alireza Razavian, Rozhina Hamidi, Khadije Yousefi, Susan Borzou, Zohaib Khurshid
International Journal of Dentistry.2022; 2022: 1. CrossRef
Efficacy Of Calcium Silicate-Based Sealers In Root Canal Treatment: A Systematic Review
Hattan Mohammed Omar Baismail, Mohammed Ghazi Moiser Albalawi, Alaa Mofareh Thoilek Alanazi, Muhannad Atallah Saleem Alatawi, Badr Soliman Alhussain
Annals of Dental Specialty.2021; 9(1): 87. CrossRef

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The effect of individualization of fiberglass posts using bulk-fill resin-based composites on cementation: an in vitro study: Rodrigo Barros Esteves Lins, Jairo Matozinho Cordeiro, Carolina Perez Rangel, Thiago Bessa Marconato Antunes, Luís Roberto Marcondes Martins; Restor Dent Endod 2019;44(4):e37. Published online October 18, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e37

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Objectives

This study evaluated the bond strength of various fiberglass post cementation techniques using different resin-based composites.

Materials and Methods

The roots from a total of 100 bovine incisors were randomly assigned to 5 treatment groups: G1, post + Scotchbond Multi-Purpose (SBMP) + RelyX ARC luting agent; G2, relined post (Filtek Z250) + SBMP + RelyX ARC; G3, individualized post (Filtek Z250) + SBMP; G4, individualized post (Filtek Bulk-Fill) + SBMP; G5, individualized post (Filtek Bulk-Fill Flow) + SBMP. The samples were subjected to the push-out (n = 10) and pull-out (n = 10) bond strength tests. Data from the push-out bond strength test were analyzed using 2-way analysis of variance (ANOVA) with the Bonferroni post hoc test, and data from the pull-out bond strength test were analyzed using 1-way ANOVA.

Results

The data for push-out bond strength presented higher values for G2 and G5, mainly in the cervical and middle thirds, and the data from the apical third showed a lower mean push-out bond strength in all groups. No significant difference was noted for pull-out bond strength among all groups. The most frequent failure modes observed were adhesive failure between dentine and resin and mixed failure.

Conclusions

Fiberglass post cementation using restorative and flowable bulk-fill composites with the individualization technique may be a promising alternative to existing methods of post cementation.

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Effects of a relined fiberglass post with conventional and self-adhesive resin cement
Wilton Lima dos Santos Junior, Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Luís Roberto Marcondes Martins
Restorative Dentistry & Endodontics.2024;[Epub] CrossRef
Fracture resistance of weakened roots restored with relined or milled CAD-CAM glass fiber posts
Belizane das Graças Oliveira MAIA, Thais da Silva Alves SANTOS, Cláudio Antonio Talge CARVALHO, Francielle Silvestre VERNER, Rafael Binato JUNQUEIRA
Dental Materials Journal.2023; 42(1): 92. CrossRef
Evaluation of pretreatments on intra‐radicular dentin bond strength of self‐adhesive resin cements
Marina Rodrigues Santi, Rodrigo Barros Esteves Lins, Beatriz Ometto Sahadi, Luís Roberto Marcondes Martins, Jorge Rodrigo Soto‐Montero
Journal of Esthetic and Restorative Dentistry.2022; 34(7): 1051. CrossRef
Comparison of the Mechanical Properties and Push-out Bond Strength of Self-adhesive and Conventional Resin Cements on Fiber Post Cementation
MR Santi, RBE Lins, BO Sahadi, JR Soto-Montero, LRM Martins
Operative Dentistry.2022; 47(3): 346. CrossRef
Glass fiber posts
Renata Pereira, Rodrigo Barros Esteves Lins, Victória Castelan Rodrigues, Débora Alves Nunes Leite Lima, Luís Roberto Marcondes Martins, Flávio Henrique Baggio Aguiar
Brazilian Journal of Oral Sciences.2020; 19: e207508. CrossRef

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Dentinal defects induced by 6 different endodontic files when used for oval root canals: an in vitro comparative study: Ajinkya M Pawar, Bhagyashree Thakur, Anda Kfir, Hyeon-Cheol Kim; Restor Dent Endod 2019;44(3):e31. Published online July 29, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e31

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Objectives

To compare the formation of dentinal defects using stainless-steel hand K-files (HFs), rotary files, reciprocating files, and Self-Adjusting File (SAF), when used for oval root canals.

Materials and Methods

One hundred and forty extracted human mandibular premolar with single root and oval canal were selected for this study. Oval canals were confirmed by exposing to mesio-distal and bucco-lingual radiographs. Teeth with open apices or anatomic irregularities were excluded. All selected teeth were de-coronated perpendicular to the long axis of the tooth, leaving roots segments approximately of 16 mm in length. Twenty teeth were left unprepared (control), and the remaining 120 teeth were divided into 6 groups (n = 20) and instrumented using HF (size 40/0.02), Revo-S (RS; size 40/0.06), ProTaper NEXT (PTN; size 40/0.06), WaveOne (WO; size 40/0.09), RECIPROC (RC; size 40/0.06), and the SAF (2 mm). Roots were then sectioned 3, 6, and 9 mm from the apex, and observed under stereomicroscope, for presence of dentinal defects. “No defect” was defined as root dentin that presented with no visible microcracks or fractures. “Defect” was defined by microcracks or fractures in the root dentin.

Results

The control, HF, and SAF did not exhibit any dentinal defects. In roots instrumented by RS, PTN, WO, and RC files exhibited microcracks (incomplete or complete) in 40%, 30%, 55%, and 50%, respectively.

Conclusions

The motor-driven root canal instrumentation with rotary and reciprocating files may create microcracks in radicular dentine, whereas the stainless-steel hand file instrumentation, and the SAF produce minimal or less cracks.

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The push-out bond strength of BIOfactor mineral trioxide aggregate, a novel root repair material: Makbule Bilge Akbulut, Durmus Alperen Bozkurt, Arslan Terlemez, Melek Akman; Restor Dent Endod 2019;44(1):e5. Published online January 28, 2019; DOI: https://doi.org/10.5395/rde.2019.44.e5

Abstract PDF PubReader ePub

Objectives

The aim of this in vitro study was to evaluate the push-out bond strength of a novel calcium silicate-based root repair material-BIOfactor MTA to root canal dentin in comparison with white MTA-Angelus (Angelus) and Biodentine (Septodont).

Materials and Methods

The coronal parts of 12 central incisors were removed and the roots were embedded in acrylic resin blocks. Midroot dentin of each sample was horizontally sectioned into 1.1 mm slices and 3 slices were obtained from each root. Three canal-like standardized holes having 1 mm in diameter were created parallel to the root canal on each dentin slice with a diamond bur. The holes were filled with MTA-Angelus, Biodentine, or BIOfactor MTA. Wet gauze was placed over the specimens and samples were stored in an incubator at 37°C for 7 days to allow complete setting. Then samples were subjected to the push-out test method using a universal test machine with the loading speed of 1 mm/min. Data was statistically analyzed using Friedman test and post hoc Wilcoxon signed rank test with Bonferroni correction.

Results

There were no significant differences among the push-out bond strength values of MTA-Angelus, Biodentine, and BIOfactor MTA (p > 0.017). Most of the specimens exhibited cohesive failure in all groups, with the highest rate found in Biodentine group.

Conclusions

Based on the results of this study, MTA-Angelus, Biodentine, and BIOfactor MTA showed similar resistances to the push-out testing.

Citations

Citations to this article as recorded by

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