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Effectiveness of silver diamine fluoride in managing hypersensitivity of molar-incisor hypomineralization affected molars: a scoping review
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Vo Truong Nhu Ngoc, Do Trong Hieu, Tran Anh Tuan, Vo Nhat Minh, Trinh Khanh Linh
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J Korean Acad Conserv Dent ;Published online April 13, 2026
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DOI: https://doi.org/10.5395/rde.2026.51.e19
[Epub ahead of print]
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 Abstract
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- This study aimed to evaluate the efficacy of dentinal hypersensitivity treatment with silver diamine fluoride (SDF) in molar-incisor hypomineralization (MIH)-affected molars. This scoping review was designed and structured according to the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and its extension for scoping reviews. A search strategy was conducted across PubMed, The Cochrane Library, ScienceDirect, and Google Scholar to identify articles related to the topic. Two authors screened titles, abstracts, and full texts for review. Five studies met the eligibility criteria, comprising four randomized controlled trials and one case report, with sample sizes ranging from four to 200 participants. All included studies reported improvements in clinical outcomes, including reduced hypersensitivity following SDF application, as indicated by lower Schiff cold air sensitivity scale scores. SDF is a promising treatment strategy for reducing hypersensitivity in MIH-affected molars; however, further research using SDF alone is needed to evaluate its exact effectiveness.
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