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Cytotoxicity and physical properties of tricalcium silicate-based endodontic materials
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Young-Eun Jang, Bin-Na Lee, Jeong-Tae Koh, Yeong-Joon Park, Nam-Eok Joo, Hoon-Sang Chang, In-Nam Hwang, Won-Mann Oh, Yun-Chan Hwang
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Restor Dent Endod 2014;39(2):89-94. Published online March 21, 2014
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DOI: https://doi.org/10.5395/rde.2014.39.2.89
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Abstract
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- Objectives
The aim of this study was to evaluate the cytotoxicity, setting time and compressive strength of MTA and two novel tricalcium silicate-based endodontic materials, Bioaggregate (BA) and Biodentine (BD). Materials and MethodsCytotoxicity was evaluated by using a 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide (XTT) assay. Measurements of 9 heavy metals (arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel, and zinc) were performed by inductively coupled plasma-mass spectrometry (ICP-MS) of leachates obtained by soaking the materials in distilled water. Setting time and compressive strength tests were performed following ISO requirements. ResultsBA had comparable cell viability to MTA, whereas the cell viability of BD was significantly lower than that of MTA. The ICP-MS analysis revealed that BD released significantly higher amount of 5 heavy metals (arsenic, copper, iron, manganese, and zinc) than MTA and BA. The setting time of BD was significantly shorter than that of MTA and BA, and the compressive strength of BA was significantly lower than that of MTA and BD. ConclusionsBA and BD were biocompatible, and they did not show any cytotoxic effects on human periodontal ligament fibroblasts. BA showed comparable cytotoxicity to MTA but inferior physical properties. BD had somewhat higher cytotoxicity but superior physical properties than MTA.
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Citations
Citations to this article as recorded by 
- Evaluation of the physical properties of bromelain-modified biodentine for direct pulp capping
Paridhi Agrawal, Manoj Chandak, Aditya Patel, Jay Bhopatkar BMC Oral Health.2024;[Epub] CrossRef - Evaluation of bioactivity, biocompatibility, and antibacterial properties of tricalcium silicate bone cement modified with wollastonite/ fluorapatite glass and glass-ceramic
H.K. Abd El-Hamid, A.M. Fayad, R.L. Elwan Ceramics International.2024; 50(14): 25322. CrossRef - Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study
Monthip Wannakajeepiboon, Chankhrit Sathorn, Chatvadee Kornsuthisopon, Busayarat Santiwong, Thanakorn Wasanapiarnpong, Pairoj Linsuwanont BMC Oral Health.2023;[Epub] CrossRef - Strength of a cement-based dental material: Early age testing and first micromechanical modeling at mature age
Petr Dohnalík, Christian Hellmich, Gilles Richard, Bernhard L. A. Pichler Frontiers in Bioengineering and Biotechnology.2023;[Epub] CrossRef - Calcium silicate and calcium aluminate cements for dentistry reviewed
Carolyn Primus, James L. Gutmann, Franklin R. Tay, Anna B. Fuks Journal of the American Ceramic Society.2022; 105(3): 1841. CrossRef - Biomimetic Approaches in Clinical Endodontics
Naresh Kumar, Nazrah Maher, Faiza Amin, Hani Ghabbani, Muhammad Sohail Zafar, Francisco Javier Rodríguez-Lozano, Ricardo E. Oñate-Sánchez Biomimetics.2022; 7(4): 229. CrossRef - Effect of different manipulations on the physical, chemical and microstructural characteristics of Biodentine
Mariana Domingos Pires, Joana Cordeiro, Isabel Vasconcelos, Mariana Alves, Sérgio André Quaresma, António Ginjeira, Josette Camilleri Dental Materials.2021; 37(7): e399. CrossRef - Minimal Intervention in Dentistry: A Literature Review on Biodentine as a Bioactive Pulp Capping Material
Naji Ziad Arandi, Mohammad Thabet, Mona Abbassy BioMed Research International.2021;[Epub] CrossRef - Chitosan-Based Accelerated Portland Cement Promotes Dentinogenic/Osteogenic Differentiation and Mineralization Activity of SHED
Hasan Subhi, Adam Husein, Dasmawati Mohamad, Nik Rozainah Nik Abdul Ghani, Asma-Abdullah Nurul Polymers.2021; 13(19): 3358. CrossRef - Material Pulp Cells and Tissue Interactions
Nastaran Meschi, Biraj Patel, Nikita B. Ruparel Journal of Endodontics.2020; 46(9): S150. CrossRef - Biological Effects of Tricalcium Silicate Nanoparticle-Containing Cement on Stem Cells from Human Exfoliated Deciduous Teeth
Yoonsun Jung, Ji-Young Yoon, Kapil Dev Patel, Lan Ma, Hae-Hyoung Lee, Jongbin Kim, Jung-Hwan Lee, Jisun Shin Nanomaterials.2020; 10(7): 1373. CrossRef - Physicochemical, mechanical and cytotoxicity evaluation of chitosan-based accelerated portland cement
Hasan Subhi, Adam Husein, Dasmawati Mohamad, Asma-Abdullah Nurul Journal of Materials Research and Technology.2020; 9(5): 11574. CrossRef - Tricalcium silicate cements: osteogenic and angiogenic responses of human bone marrow stem cells
Mohamed R. W. Ali, Manal Mustafa, Asgeir Bårdsen, Athanasia Bletsa European Journal of Oral Sciences.2019; 127(3): 261. CrossRef - Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues
Carolyn M. Primus, Franklin R. Tay, Li-na Niu Acta Biomaterialia.2019; 96: 35. CrossRef - Effect of phytic acid on the setting times and tensile strengths of calcium silicate‐based cements
Ozgur Uyanik, Emre Nagas, Selen Kucukkaya Eren, Zafer C. Cehreli, Pekka K. Vallittu, Lippo V.J. Lassila Australian Endodontic Journal.2019; 45(2): 241. CrossRef - Effects of four novel root-end filling materials on the viability of periodontal ligament fibroblasts
Makbule Bilge Akbulut, Pembegul Uyar Arpaci, Ayce Unverdi Eldeniz Restorative Dentistry & Endodontics.2018;[Epub] CrossRef - Biodentine™ material characteristics and clinical applications: a 3 year literature review and update
S. Rajasekharan, L. C. Martens, R. G. E. C. Cauwels, R. P. Anthonappa European Archives of Paediatric Dentistry.2018; 19(1): 1. CrossRef - Root perforations: a review of diagnosis, prognosis and materials
Carlos Estrela, Daniel de Almeida Decurcio, Giampiero Rossi-Fedele, Julio Almeida Silva, Orlando Aguirre Guedes, Álvaro Henrique Borges Brazilian Oral Research.2018;[Epub] CrossRef - Effects of chelating agent and acids on Biodentine
V Ballal, JN Marques, CN Campos, CO Lima, RA Simão, M Prado Australian Dental Journal.2018; 63(2): 170. CrossRef - Biological interactions of a calcium silicate based cement (Biodentine™) with Stem Cells from Human Exfoliated Deciduous teeth
Eirini Athanasiadou, Maria Paschalidou, Anna Theocharidou, Nikolaos Kontoudakis, Konstantinos Arapostathis, Athina Bakopoulou Dental Materials.2018; 34(12): 1797. CrossRef - Retention of BioAggregate and MTA as coronal plugs after intracanal medication for regenerative endodontic procedures: an ex vivo study
Suzan Abdul Wanees Amin, Shaimaa Ismail Gawdat Restorative Dentistry & Endodontics.2018;[Epub] CrossRef - Management of Dens Invaginatus Type II Associated with Immature Apex and Large Periradicular Lesion Using Platelet-rich Fibrin and Biodentine
Shruti Goel, Ruchika Roongta Nawal, Sangeeta Talwar Journal of Endodontics.2017; 43(10): 1750. CrossRef - Brain aluminium accumulation and oxidative stress in the presence of calcium silicate dental cements
K Demirkaya, B Can Demirdöğen, Z Öncel Torun, O Erdem, E Çırak, YM Tunca Human & Experimental Toxicology.2017; 36(10): 1071. CrossRef - Calcium silicate‐based cements: composition, properties, and clinical applications
Alaa E. Dawood, Peter Parashos, Rebecca H.K. Wong, Eric C. Reynolds, David J. Manton Journal of Investigative and Clinical Dentistry.2017;[Epub] CrossRef - Biological response of commercially available different tricalcium silicate-based cements and pozzolan cement
Serhat Köseoğlu, Tuğba Pekbağryank, Ebru Kucukyilmaz, Mehmet Sağlam, Sukru Enhos, Ayşe Akgün Microscopy Research and Technique.2017; 80(9): 994. CrossRef - Modified tricalcium silicate cement formulations with added zirconium oxide
Xin Li, Kumiko Yoshihara, Jan De Munck, Stevan Cokic, Pong Pongprueksa, Eveline Putzeys, Mariano Pedano, Zhi Chen, Kirsten Van Landuyt, Bart Van Meerbeek Clinical Oral Investigations.2017; 21(3): 895. CrossRef - Cytotoxic effects of mineral trioxide aggregate, calcium enrichedmixture cement, Biodentine and octacalcium pohosphate onhuman gingival fibroblasts
Eshagh A. Saberi, Narges Farhadmollashahi, Faroogh Ghotbi, Hamed Karkeabadi, Roholla Havaei Journal of Dental Research, Dental Clinics, Dental Prospects.2016; 10(2): 75. CrossRef - The effect of working time on the displacement of Biodentine™ beneath prefabricated stainless steel crown: a laboratory study
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