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The effect of using nanoparticles in bioactive glass on its antimicrobial properties
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Maram Farouk Obeid, Kareim Moustafa El-Batouty, Mohammed Aslam
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Restor Dent Endod 2021;46(4):e58. Published online October 29, 2021
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DOI: https://doi.org/10.5395/rde.2021.46.e58
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Abstract
PDFPubReaderePub
- Objectives
This study addresses the effect of using nanoparticles (np) on the antimicrobial properties of bioactive glass (BAG) when used in intracanal medicaments against Enterococcus faecalis (E. faecalis) biofilms. Materials and MethodsE. faecalis biofilms, grown inside 90 root canals for 21 days, were randomly divided into 4 groups according to the antimicrobial regimen followed (n = 20; BAG-np, BAG, calcium hydroxide [CaOH], and saline). After 1 week, residual live bacteria were quantified in terms of colony-forming units (CFU), while dead bacteria were assessed with a confocal laser scanning microscope. ResultsAlthough there was a statistically significant decrease in the mean CFU value among all groups, the nano-group performed the best. The highest percentage of dead bacteria was detected in the BAG-np group, with a significant difference from the BAG group. ConclusionsThe reduction of particle size and use of a nano-form of BAG improved the antimicrobial properties of the intracanal treatment of E. faecalis biofilms
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