Restorative Dentistry & Endodontics

Christos Gogos

5 Articles

Fracture resistance of regenerated immature teeth in different simulated stages of root development: an in vitro cyclic loading study: Kyveli-Artemis Polydora, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos; Restor Dent Endod 2026;51(2):e21. Published online April 28, 2026; DOI: https://doi.org/10.5395/rde.2026.51.e21

Abstract PDF Supplementary Material PubReader ePub: Objectives
This in vitro study aimed to assess the fracture resistance of simulated stages of root maturation following regenerative endodontic treatment using a cyclic loading method.
Methods
Ninety extracted maxillary central incisors were randomly allocated into three experimental groups representing different stages of root development, following revitalization: Group A for completely immature teeth immediately after treatment; Group B for teeth with apical closure, and Group C for teeth with apical closure and wall thickening. Two control groups were also included: Group D for intact teeth and Group E for simulated immature teeth without the bioceramic material. Following simulation of immature apices and treatment with a bioceramic material, all specimens were subjected to cyclic loading using a step-stress fatigue protocol until failure. The number of cycles to fracture and the peak load were recorded and statistically analyzed.
Results
Statistically significant differences in loading forces were observed between the negative control group (Group D) and Groups A, B, and E (p < 0.05). However, no statistically significant differences were detected among the experimental groups. These results indicate that apical closure and dentinal wall thickening alone did not substantially improve mechanical reinforcement under cyclic loading conditions.
Conclusions
Although intact teeth exhibited superior mechanical performance, apical closure and wall thickening alone were insufficient to enhance reinforcement under cyclic loading.

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A scientometric, bibliometric, and thematic map analysis of hydraulic calcium silicate root canal sealers: Anastasios Katakidis, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos; Restor Dent Endod 2023;48(4):e41. Published online November 13, 2023; DOI: https://doi.org/10.5395/rde.2023.48.e41

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Objectives

This scientometric and bibliometric analysis explored scientific publications related to hydraulic calcium silicate-based (HCSB) sealers used in endodontology, aiming to describe basic bibliometric indicators and analyze current research trends.

Materials and Methods

A comprehensive search was conducted in Web of Science and Scopus using specific HCSB sealer and general endodontic-related terms. Basic research parameters were collected, including publication year, authorship, countries, institutions, journals, level of evidence, study design and topic of interest, title terms, author keywords, citation counts, and density.

Results

In total, 498 articles published in 136 journals were retrieved for the period 2008–2023. Brazil was the leading country, and the universities of Bologna in Italy and Sao Paolo in Brazil were represented equally as leading institutions. The most frequently occurring keywords were “calcium silicate,” “root canal sealer MTA-Fillapex,” and “biocompatibility,” while title terms such as “calcium,” “sealers,” “root,” “canal,” “silicate based,” and “endodontic” occurred most often. According to the thematic map analysis, “solubility” appeared as a basic theme of concentrated research interest, and “single-cone technique” was identified as an emerging, inadequately developed theme. The co-occurrence analysis revealed 4 major clusters centered on sealers’ biological and physicochemical properties, obturation techniques, retreatability, and adhesion.

Conclusions

This analysis presents bibliographic features and outlines changing trends in HCSB sealer research. The research output is dominated by basic science articles scrutinizing the biological and specific physicochemical properties of commonly used HCSB sealers. Future research needs to be guided by studies with a high level of evidence that utilize innovative, sophisticated technologies.

Citations

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A Scientometric Review of Practical Applications in Quantum Natural Language Processing (QNLP): Trends, Gaps, and Research Opportunities
Victor R. Silva, Fábio R. Barbosa, Jasson C. Silva, Francisco J. Santos, Ricardo A. L. Rabelo, Joel J. P. C. Rodrigues
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Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs
José Luis Sanz, Sergio López-García, David García-Bernal, Francisco Javier Rodríguez-Lozano, Leopoldo Forner, Adrián Lozano, Laura Murcia
Clinical Oral Investigations.2024;[Epub] CrossRef
Analyzing collaboration and impact: A bibliometric review of four highly published authors’ research profiles on collaborative maps
Willy Chou, Julie Chi Chow
Medicine.2024; 103(28): e38686. CrossRef

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7 Web of Science
9 Crossref

Traditional and minimally invasive access cavities in endodontics: a literature review: Ioanna Kapetanaki, Fotis Dimopoulos, Christos Gogos; Restor Dent Endod 2021;46(3):e46. Published online August 13, 2021; DOI: https://doi.org/10.5395/rde.2021.46.e46

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The aim of this review was to evaluate the effects of different access cavity designs on endodontic treatment and tooth prognosis. Two independent reviewers conducted an unrestricted search of the relevant literature contained in the following electronic databases: PubMed, Science Direct, Scopus, Web of Science, and OpenGrey. The electronic search was supplemented by a manual search during the same time period. The reference lists of the articles that advanced to second-round screening were hand-searched to identify additional potential articles. Experts were also contacted in an effort to learn about possible unpublished or ongoing studies. The benefits of minimally invasive access (MIA) cavities are not yet fully supported by research data. There is no evidence that this approach can replace the traditional approach of straight-line access cavities. Guided endodontics is a new method for teeth with pulp canal calcification and apical infection, but there have been no cost-benefit investigations or time studies to verify these personal opinions. Although the purpose of MIA cavities is to reflect clinicians' interest in retaining a greater amount of the dental substance, traditional cavities are the safer method for effective instrument operation and the prevention of iatrogenic complications.

Citations

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Benefits of Using Magnification in Access Cavity Preparation by Undergraduate Dental Students: A Micro‐Computed Tomography Study
Manal Almaslamani, Okba Mahmoud, Aya Ali, Mawada Abdelmagied
European Journal of Dental Education.2026; 30(1): 77. CrossRef
Impact of conservative and traditional endodontic accesses on the strength of maxillary zirconia crowns
Carlos A. Jurado, Gustavo Morrice, Mark Antal, Silvia Rojas‐Rueda, Francisco X. Azpiazu‐Flores, Brian R. Morrow, Franklin Garcia‐Godoy, Damian J. Lee
Journal of Prosthodontics.2026; 35(3): 323. CrossRef
Effect of access cavity design on canal instrumentation efficiency and fracture resistance in mandibular molars: A cone-beam computed tomography study
Dalia Al-Harith, Rawan Meshal AlOtaibi
Saudi Journal of Oral Sciences.2025; 12(1): 72. CrossRef
Full-coverage Porcelain-fused-to-metal Crown with Guided Access for Future Endodontic Treatment: A Comparative Pilot In Vitro Study
Mohammed Mashyakhy, Hemant Chourasia, Hafiz Adawi, Abdulaziz Abu-Melha, Elham Khudhayr, Rafif Bakri, Taif Kameli, Khalid Moashy, Hitesh Chohan
The Journal of Contemporary Dental Practice.2025; 26(3): 234. CrossRef
Comparative evaluation of root canal morphology in mandibular first premolars with deep radicular grooves using direct vision, dental operating microscope, 2D radiographic visualisation and micro-computed tomography
Mohmed Isaqali Karobari, Hany Mohamed Aly Ahmed, Mohd Fadhli Bin Khamis, Norliza Ibrahim, Tahir Yusuf Noorani, Miriam Fatima Zaccaro Scelza
PLOS One.2025; 20(7): e0329439. CrossRef
A Finite Element Method Study of Stress Distribution in Dental Hard Tissues: Impact of Access Cavity Design and Restoration Material
Mihaela-Roxana Boțilă, Dragos Laurențiu Popa, Răzvan Mercuț, Monica Mihaela Iacov-Crăițoiu, Monica Scrieciu, Sanda Mihaela Popescu, Veronica Mercuț
Bioengineering.2024; 11(9): 878. CrossRef
Impact of Access Cavity Design on Fracture Resistance of Endodontically Treated Maxillary First Premolar: In Vitro
Anju Daniel, Abdul Rahman Saleh, Anas Al-Jadaa, Waad Kheder
Brazilian Dental Journal.2024;[Epub] CrossRef
Management of Traumatized Teeth With Severely Calcified Canals and Minimally Invasive Access Cavity Using the AReneto® System: A Case Report
Pucha Sai Manaswini, Varun Prabhuji, Champa C, Srirekha A, Veena S Pai
Cureus.2024;[Epub] CrossRef
Exploring the Impact of Access Cavity Designs on Canal Orifice Localization and Debris Presence: A Scoping Review
Mario Dioguardi, Davide La Notte, Diego Sovereto, Cristian Quarta, Andrea Ballini, Vito Crincoli, Riccardo Aiuto, Mario Alovisi, Angelo Martella, Lorenzo Lo Muzio
Clinical and Experimental Dental Research.2024;[Epub] CrossRef
The effect of computer aided navigation techniques on the precision of endodontic access cavities: A systematic review and meta-analysis
P. R. Kesharani, S. D. Aggarwal, N. K. Patel, J. A. Patel, D. A. Patil, S. H. Modi
Endodontics Today.2024; 22(3): 244. CrossRef
Minimally Invasive Access Cavity Designs: A Review
Sushmita Rane, Varsha Pandit, Ashwini Gaikwad, Shivani Chavan, Rajlaxmi Patil, Mrunal Shinde
Journal of Pharmacy and Bioallied Sciences.2024; 16(Suppl 3): S1971. CrossRef
Influence of Cavity Designs on Fracture Resistance: Analysis of the Role of Different Access Techniques to the Endodontic Cavity in the Onset of Fractures: Narrative Review
Mario Dioguardi, Davide La Notte, Diego Sovereto, Cristian Quarta, Angelo Martella, Andrea Ballini, Cornelis H. Pameijer
The Scientific World Journal.2024;[Epub] CrossRef
Digital precision meets dentin preservation: PriciGuide™ system for guided access opening
Varun Prabhuji, A. Srirekha, Veena Pai, Archana Srinivasan, S. M. Laxmikanth, Shwetha Shanbhag
Journal of Conservative Dentistry and Endodontics.2024; 27(8): 884. CrossRef
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Jaydip Marvaniya, Kishan Agarwal, Dhaval N Mehta, Nirav Parmar, Ritwik Shyamal , Jenee Patel
Cureus.2022;[Epub] CrossRef

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Flow characteristics and alkalinity of novel bioceramic root canal sealers: Anastasios Katakidis, Konstantinos Sidiropoulos, Elisabeth Koulaouzidou, Christos Gogos, Nikolaos Economides; Restor Dent Endod 2020;45(4):e42. Published online August 18, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e42

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Objective

This study aimed to examine the physical properties (pH and flow) of 2 novel bioceramic sealers.

Materials and Methods

The tested sealers were a calcium hydroxide sealer (Sealapex) and 2 bioceramic sealers (BioRoot RCS and TotalFill BC Sealer). Flow measurements were conducted according to ISO 6876/2012, with a press method of 0.05 mL of sealer. The pH of fresh samples was tested immediately after manipulation, while set samples were stored for 3 times the recommended setting time. The predetermined time intervals ranged from 3 minutes to 24 hours for fresh samples and from 10 minutes to 7 days and 4 weeks for the set samples. Analysis of variance was performed, with p = 0.05 considered indicating significance.

Results

The mean flow values were 26.99 mm for BioRoot, 28.19 for Sealapex, and 30.8 mm for TotalFill BC Sealer, satisfying the ISO standard. In the set samples, BioRoot RCS had higher pH values at 24 hours to 1 week after immersion in distilled water. At 2 weeks, both bioceramic sealers had similar pH values, greater than that of Sealapex. In the fresh samples, the bioceramic sealers had significantly higher initial pH values than Sealapex (p < 0.05). At 24 hours post-immersion, all sealers showed an alkaline pH, with the highest pH observed for TotalFill.

Conclusions

The TotalFill BC Sealer demonstrated the highest flow. The bioceramic sealers initially presented higher alkaline activity than the polymeric calcium hydroxide sealer. However, at 3 and 4 weeks post-immersion, all sealers had similar pH values.

Citations

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In vitro comparative evaluation of physicochemical and mechanical properties, cytocompatibility, and antimicrobial efficacy of various bioceramic root canal sealers
Fushi Wang, Jiaxing Li, Jingjing Wan, Siyuan Li, Shijia Tang, Li Wang, Liuyan Meng
Ceramics International.2026; 52(7): 9561. CrossRef
Comparative analysis between resin-based root canal sealer and recent bioceramic-based root canal sealers using MicroCT, film thickness, and solubility
Amira Galal Ismail, Manar M. Galal, Tamer M. Hamdy
Journal of Oral Biology and Craniofacial Research.2026; 16(2): 101400. CrossRef
Setting Characteristics, Solubility, Bioactivity and Interaction with Dentin of Four Calcium Silicate-Based Endodontic Sealers
Areti Dimitra Vrochari, Anastasia Agrafioti, Maria Dimitriadi, George Eliades
Journal of Functional Biomaterials.2026; 17(4): 192. CrossRef
Cryotherapy-Driven Modulation of Postoperative Pain in Single-Visit Endodontic Treatment Across Different Obturation Materials: A Retrospective Study
Kaan Ilıcalı, Ahter Şanal Çıkman, Özge Başar
Journal of Clinical Medicine.2026; 15(10): 3899. CrossRef
Functional and Bioactive Performance of Premixed Bioceramic Sealers with Warm Obturation: A Scoping Review
Patryk Wiśniewski, Stanisław Krokosz, Małgorzata Pietruska, Anna Zalewska
Gels.2025; 11(11): 932. CrossRef
Physicochemical properties of AH plus bioceramic sealer, Bio-C Sealer, and ADseal root canal sealer
Tamer M. Hamdy, Manar M. Galal, Amira Galal Ismail, Shehabeldin Saber
Head & Face Medicine.2024;[Epub] CrossRef
Characterization and Assessment of Physical Properties of 3 Single Syringe Hydraulic Cement–based Sealers
Veksina Raman, Josette Camilleri
Journal of Endodontics.2024; 50(3): 381. CrossRef
The Impact of Silver Nanoparticles on Dentinal Tubule Penetration of Endodontic Bioceramic Sealer
Sundus Bukhary, Sarah Alkahtany, Amal Almohaimede, Nourah Alkhayatt, Shahad Alsulaiman, Salma Alohali
Applied Sciences.2024; 14(24): 11639. CrossRef
Influence of root canal moisture on the penetration of TotalFill bioceramic sealer into the dentinal tubules: A confocal laser scanning microscopy study
Archika M Singh, Tarek M Elsewify, Walid S El-Sayed, Husam H Nuawafleh, Ranya F Elemam, Bassem M Eid
Saudi Endodontic Journal.2024; 14(2): 187. CrossRef
Unusual Canal Morphology in Mandibular Premolars With Two Distal and One Mesial Canal: A Case Series
Jinesh A, Sanjana Jayakumar Nair, Saurabh Gupta, Harsh Chansoria, Gaurav Rawat
Cureus.2024;[Epub] CrossRef
A scientometric, bibliometric, and thematic map analysis of hydraulic calcium silicate root canal sealers
Anastasios Katakidis, Konstantinos Kodonas, Anastasia Fardi, Christos Gogos
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
Thermal, chemical and physical analysis of VDW.1Seal, Fill Root ST, and ADseal root canal sealers
Shehabeldin Saber, Manar M. Galal, Amira Galal Ismail, Tamer M. Hamdy
Scientific Reports.2023;[Epub] CrossRef
α-tricalcium phosphate/fluorapatite-based cement - promising dental root canal filling material
Abdul Kazuz, Zeljko Radovanovic, Djordje Veljovic, Vesna Kojic, Dimitar Jakimov, Tamara Vlajic-Tovilovic, Vesna Miletic, Rada Petrovic, Djordje Janackovic
Processing and Application of Ceramics.2022; 16(1): 22. CrossRef

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Top 50 cited articles on dental stem cell research: Konstantinos Kodonas, Anastasia Fardi, Christos Gogos, Nikolaos Economides; Restor Dent Endod 2020;45(2):e17. Published online February 11, 2020; DOI: https://doi.org/10.5395/rde.2020.45.e17

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Objectives

Citation analysis provides a unique insight into how scientific interests and research trends have changed over time. The aim of this study was to report on the 50 top-cited papers in dental stem cell research using the Science Citation Index Expanded provided by the Web of Science database to determine the academic importance of each contribution.

Materials and Methods

After the screening, article title and type, total citations and citations per year, publication journal, publication year, first and senior authors, country of origin, institution, and university of reprint author were documented for the 50 top-cited articles in dental stem cell research. Keyword analysis was performed to determine which keywords were most/least popular.

Results

Top 50-cited articles were cited between 179 to 2,275 times. The majority of papers were published in 2008 and originated from the United States with the highest contribution from the National Institute of Dental & Craniofacial Research. Journal of Dental Research published the highest number of top-cited articles, followed by Stem Cells and Journal of Endodontics. The greatest number of articles was published by two individual authors, Shi and Gronthos. Among 197 unique keywords, dental pulp stem cells and mesenchymal stem cells were the most frequently used. Thirty-eight of the 50 most cited articles were original articles, and 37 of them were in the field of basic science.

Conclusions

Basic science studies in dental stem cell research published in high impact factor journals had the highest citation rates.

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Yuka Kato, Insoon Chang, Satoshi Yokose
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Revitalizing Dental Diagnostics: A Bibliometric Analysis of the Rising Impact of 3D Imaging in Dentistry
Ravinder S Saini , Mario Alberto Alarcón-Sánchez , Naseer Ahmed , Artak Heboyan
The Journal of Basic and Clinical Dentistry.2024; 1(1): 1. CrossRef
Contemporary research trends on nanoparticles in endodontics: a bibliometric and scientometric analysis of the top 100 most-cited articles
Sıla Nur Usta, Zeliha Uğur-Aydın, Kadriye Demirkaya, Cumhur Aydın
Restorative Dentistry & Endodontics.2023;[Epub] CrossRef
The 100 top-cited articles in uveitis from 1950 to 2022
Li Huang, Wei Yang, Tianyu Yao, Zhiru Zhang, Xiaorong Gao, Yujiao Dan, Yue He
International Ophthalmology.2023; 43(12): 4631. CrossRef
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Martina Ferrillo, Vittorio Gallo, Lorenzo Lippi, Alessandro Bruni, Roberta Montrella, Claudio Curci, Dario Calafiore, Marco Invernizzi, Mario Migliario, Alessandro de Sire
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Alessandro Bruni, Francesca Giulia Serra, Vittorio Gallo, Andrea Deregibus, Tommaso Castroflorio
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