html {
     margin-top:  0%;
     margin-left:  0%;
     margin-right: 0%;
     margin-bottom: 0%;     
     font-family: "Times New Roman";
     }

body {
	background-color: #ffffff;
	margin: 0;
	margin-top: 0px;
	margin-right: 10px;
	margin-bottom: 0px;
	margin-left: 0px;
	min-width: 1010px;
	
	// IE8 below
	border-right : 1px solid #ddd;	
}


.grid {
	min-width: 98.9999%;
}


.shadow {
	
	// IE8 below
	border-right : 1px solid #ddd;
	
	// IE9 or Higher
	width: 98.9999%;
	
	-webkit-box-shadow: 0.4em 0.4em 0.5em rgba(0,0,0,.3);
	-moz-box-shadow: 0.4em 0.4em 0.5em rgba(0,0,0,.3);
	box-shadow: 0.4em 0.4em 0.5em rgba(0,0,0,.3);
}


.portlet {
	border-top: 2px solid #d7000f;
	padding-top: .461em;
	margin: .769em 0 2.154em 0;
	overflow: visible;
	line-height: 1.231em;
	zoom: 1;
}

.portlet IMG {
  margin-right:0.3em;
}

.portlet_crossmark {
 margin: 0;
 padding: 0;
  height: 3.1em;
 overflow: visible;
 zoom: 1;
}

.portlet_head {
	margin-bottom: .461em;
	position: relative;
}

.portlet_subhead {
	margin-top: 0.7em;
	margin-bottom: -0.4em;
	position: relative;
	}

.portlet_title, .sensor_title {
	color: #d7000f;
	font-size: 0.9em;
	margin-right: 2em;
}

.portlet_content {		
	font-size: 0.9em;
	position: relative;
	margin: 0px;
}

.portlet_content UL {
	-webkit-margin-before: 0em;
	-webkit-margin-after: 0em;
	-webkit-margin-start: 0px;
	-webkit-margin-end: 0px;
	-webkit-padding-start: 0px;	
	
	LINE-HEIGHT: 1.231em; 
	LIST-STYLE-TYPE: none; 
	margin: 0.5em;
	padding: 0px;
}

.portlet_content LI {
	PADDING-LEFT: 0px; 
	COLOR: black;
	margin: 0.3em, 0.3em;	
	FONT-SIZE: 10pt;	
	FONT-WEIGHT: normal;
}

#portlet_content_Format A {
	TEXT-DECORATION: none;	
	BORDER-BOTTOM: black 1px dotted;	
	COLOR: #000000;
}

#portlet_content_Format A:hover {
	COLOR: #000000;
}

#portlet_content_Format A:active {
	COLOR: #000000;
}

#portlet_content_Format A:visited {
	COLOR: #000000;
}

#portlet_content_MeSH A {
	TEXT-DECORATION: none;
	overflow:visible;
	word-wrap: break-word;
	BORDER-BOTTOM: black 1px dotted;
	COLOR: #000000;
	}

#portlet_content_MeSH A:hover {
	COLOR: #000000;
	}

#portlet_content_MeSH A:active {
	COLOR: #000000;
	}

#portlet_content_MeSH A:visited {
	COLOR: #000000;
	}

#portlet_content_MeSH li {
	margin-left:14px;
	}

#portlet_content_ORCID A {
	COLOR: #000000;
	TEXT-DECORATION: none;
	FONT-SIZE: 0.88em;
	BORDER-BOTTOM: black 1px dotted;	
}

#portlet_content_ORCID IMG {
	margin-right: 0em;	
}

.more_margin {
  margin-bottom: 0.6em;
}

#portlet_content_carousel A:hover {
	COLOR: #000000;
}

#portlet_content_carousel A:active {
	COLOR: #000000;
}

#portlet_content_carousel A:visited {
	COLOR: #000000;
}


.portlet_content_supplementary_materials_video {
	margin-top:0.6em;
	margin-bottom:1.8em;
	font-size: 0.9em;	
}


portlet_content_supplementary_materials_video_view {
	margin-top:0.3em;
	margin-bottom:0;
	width: 200px;
	height: 180px;		
}

.portlet_content_supplementary_materials_video_view video {
	width: 200px;
	margin: 0;
}

.portlet_content_supplementary_materials_video A {
	TEXT-DECORATION: none;	
	BORDER-BOTTOM: black 1px dotted;	
	COLOR: #000000;	
}


.portlet_content A {
	TEXT-DECORATION: none;	
	COLOR: #000000;
}

.portlet_content A:hover {
	COLOR: #000000;
}
.portlet_content A:active {
	COLOR: #000000;
}

.portlet_content A:visited {
	COLOR: #000000;
}

.portlet_content_carousel{
	margin: 0.5em;
}


#ArticleContentsWrap {
	overflow: hidden;
	width: 850px;
}

#ArticleContents {
	width: 600px;
	float: left;
}

#ArticleContentsPortlet {	
	margin-top: 20px;
	margin-left: 20px;
	width: 230px;
	float: left;
}		

#ArticleContentsTopIconBar {	
    margin: 0;
    padding: 0;
}

HR.article-doctype-openaccess-underbar {
	height: 1px;	
    border: 0; 
    border-top: 1px solid #d7000f;
    padding: 0;
    
    clear: both;
    display: block;    	
    margin: 5px 0;
    *margin: -2px 0; /* ie7 and below */ 
    
}

HR.article-menubar-top {
	height: 2px;	
    border: 0; 
    border-top: 2px solid #d7000f;
    padding: 0;
    
    clear: both;
    display: block;	
    margin: 5px 0;
    *margin: -2px 0; /* ie7 and below */
}

HR.article-menubar-bottom {
	display: block; 
	height: 2px;	
    border: 0; 
    border-top: 2px solid #d7000f;
    padding: 0;
    
    clear: both;
    display: block;
    margin: 5px 0;
    *margin: -2px 0; /* ie7 and below */    
}


a,img,input{selector-dummy: expression(this.hideFocus=true);}

.img_sub {
	font-size:0;
}

.jTitle {
	color: black;
	FONT-WEIGHT: bold;
	FONT-SIZE: 170%;
	FONT-FAMILY: Times new roman;
	text-decoration: none;
}

.ArticleInfor {
	font-size: 9pt;
	line-height: 12pt;
	display:inline;
	color: #949494;
}

.JournalInfor {
	font-family: Verdana;
	font-size: 70%;
	line-height: 120%;
	display:inline;
	color: #000000;
}

.JournalISSN {
	font-family: Verdana;
	font-size: 100%;
	display:inline;
	color: #6C6C6C;
}

.notice {
	font-family: Verdana;
	color: #black;
	font-size: 70%;
}

.Verdana {
	font-family: Verdana;
	font-size: 75%;
}

.copyright {
	font-family: Verdana;
	font-size: 8pt;
	line-height: 12pt;
	display:inline;
	color: #000201;
	text-decoration: none;
}

/* rules */
hr.part-rule {
    color: #555555;
    width: 100%;
    align: center;
    margin-top: 5pt;
    margin-bottom: 5pt;
    }

hr.section-rule {
    color: #9CCDFF;
    width: 100%;
    height: 5px;
    align: center;
    margin-top: 3pt;
    margin-bottom: 3pt;
    }

/* superior numbers which are cross-references */
.xref {
    color: red;
    }
    
/* generated text */     
.gen {
    color: gray;
    }

/* --------------- Titling levels -------------------- */


/* titling level 1: document title */
.tl-document {
   display: block;
   font-family: times new roman;
   font-size: 15pt;
   font-weight: bold;
   color: black;
   line-height: 130%;
   text-align: left;
   }

/* titling level 2: main document parts */
.tl-main-part {
	FONT-WEIGHT: bold;
	FONT-SIZE: 12pt;
	color: white;
	FONT-FAMILY: Verdana, sans-serif;
}
 
/* titling level 3: first-level sections of main parts */
 .tl-section-level {
   display: block;
   font-family: helvetica, sans-serif;
   font-size: 12pt;
   font-weight: bold;
   color: blue;
   line-height: 130%;
   }
 
/* titling level 4: lowest designed level */
.tl-lowest-section {
   display: block;
   font-family: helvetica, sans-serif;
   font-size: 11pt;
   font-weight: bold;
   color: black;
   line-height: 120%;
   }
   
/* default titling level */
.tl-default {
   display: block;
   font-family: helvetica, sans-serif;
   font-size: 12pt;
   font-weight: bold;
   color: gray;
   line-height: 130%;
   margin-top: 5pt;
  }


/* FORM style */
.input
{
	font-family: Verdana; 
	color: #454545; 
	font-size: 10pt; 
	line-height:14px; 
	BORDER: #BEBEBE; 1px solid; 
}

/* table style */
Table.Form {
	font-family: Verdana; 
	color: #000000; 
	font-size: 9pt; 
	line-height:130%; 
}

Table.menu {
	FONT-SIZE: 13px;
	COLOR: #d7000f;
	FONT-FAMILY: verdana;
}

.menu a {
	FONT-SIZE: 12px;
	FONT-FAMILY: verdana;
	COLOR:  #585657;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
	font-weight: normal;
}

Table.d {
	FONT-SIZE: 100%;
	FONT-FAMILY: Times new roman;
	display: inline;
	color: black;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.d a {
	color: #ea4f23;
	text-decoration: none;
}

.br2 {
	background-repeat: no-repeat;
}

.forthcoming_issue {
	color: #999999;
	FONT-SIZE: 80%;
	text-decoration: none;
}

.forthcoming_issue a:link {
	text-decoration:none;
	color: #999999;
	selector-dummy:
	expression(this.hideFocus=true);
}

.forthcoming_issue a:visited {
	text-decoration:none;
	color: #999999;
	selector-dummy:
	expression(this.hideFocus=true);
}


.forthcoming_issue a:hover {
	text-decoration:none;
	color: #FF0000;
	selector-dummy:
	expression(this.hideFocus=true);
}


.Journal p {
	line-height:160%;
}


Table.Article {
	FONT-SIZE: 100%;
	font-family: helvetica;
	display: inline;
	color: #000000;
	text-decoration: none;
}

Table.JournalBrowser {
	FONT-SIZE: 70%;
	font-family: Verdana;
	display: inline;
}

.JournalBrowser a{
	FONT-SIZE: 110%;
	display: inline;
	color: #1c1c1c;
	text-decoration: none;
}

Table.Journal {
	FONT-SIZE: 100%;
	font-family: Times new roman;
	display: inline;
	color: #000000;
	font-weight:normal;
	line-height: 130%;
}

.Journal a {
	COLOR: #DE1434;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.title01 {
	COLOR: #e80113;
	FONT-SIZE: 100%;
	font-weight:bold;
}

.title02 {
	COLOR: #6e82b4;
	FONT-SIZE: 9pt;
	font-family: Verdana;
	font-weight: bold;
}

.title03 {
	COLOR: #f13404;
	FONT-SIZE: 10pt;
	font-weight:bold;
	line-height:180%;
	font-family: Verdana;
}

.title03 a {
	COLOR: #8a8a8a;
	text-decoration: none;
}

.title04 {
	COLOR: #9b1e35;
	FONT-SIZE: 11pt;
	font-weight:bold;
	line-height:180%;
}

Table.Box3 {
	FONT-SIZE: 85%;
	font-family: Verdana;
	display: inline;
	color: #000000;
	text-decoration: none;
	line-height:130%;
	border-top:1px solid #dcdcdc;
	border-bottom:1px solid #dcdcdc;
	border-left:1px solid #dcdcdc;
	border-right:1px solid #dcdcdc;
}

.Box3 tbody td {
     color:#494949;
     vertical-align:middle;
	 text-align:center;
     border-bottom:1px solid #eeeeee;
     padding-top:4px;padding-bottom:4px;
}

Table.current {
	FONT-SIZE: 11pt;
	font-family: Times new roman;
	color: #000000;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.current a:link {
	FONT-SIZE: 12pt;
	color: #000000;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.current a:visited {
	text-decoration:none;
	color: #000000;
	selector-dummy:
	expression(this.hideFocus=true);
}

.current a:hover {
	text-decoration:none;
	color: #d7000f;
	selector-dummy:
	expression(this.hideFocus=true);
}

.current_author {
	FONT-SIZE: 10pt;
	font-family: Times new roman;
	line-height:130%;
	display: inline;
	color: #000000;
	font-weight:normal;
	text-decoration: none;
}

Table.main_menu {
	FONT-SIZE: 80%;
	font-family: Verdana;
	display: inline;
	color: #000000;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.main_menu a {
	color: #FF0000;
	text-decoration: none;
	font-weight:normal;
}

Table.box_bottom_navi {
	FONT-SIZE: 75%;
	font-family: Verdana;
	display: inline;
	color: #000000;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.box_bottom_navi a {
	color: #FFF000;
	text-decoration: none;
	font-weight:bold;
}

Table.board {
	FONT-SIZE: 90%;
	font-family: Verdana;
	display: inline;
	color: #231815;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.Title_box {
	font-family:Verdana;
	COLOR: #ffffff;
	FONT-SIZE: 10pt;
}

Table.Box_menu {
	text-decoration: none;
	border-bottom:1px solid #A0A0A0;
}

}

.Box_menu td{
	border-top:1px solid #A0A0A0;
	border-left:1px solid #A0A0A0;
	border-right:1px solid #A0A0A0;
}

Table.Archive {
	FONT-SIZE: 80%;
	font-family: helvetica;
	display: inline;
	color: #535353;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
	line-height:160%;
}

.Archive a:link {
	text-decoration:none;
	color: #999999;
	selector-dummy:
	expression(this.hideFocus=true);
}

.Archive a:visited {
	text-decoration:none;
	color: #999999;
	selector-dummy:
	expression(this.hideFocus=true);
}


.Archive a:hover {
	text-decoration:none;
	color: #7b0095;
	selector-dummy:
	expression(this.hideFocus=true);
}

td.box_archive_year {
	font-family: helvetica;
	FONT-SIZE: 100%;
	COLOR: #a0a0a0;
	text-decoration: none;
	font-weight:normal;
	border-top:3px solid #69CDF5;
	border-bottom:3px solid #69CDF5;
	border-left:3px solid #69CDF5;
	border-right:3px solid #69CDF5;
}

.box_archive_year a {
	COLOR: #a0a0a0;
	text-decoration: none;
}

Table.forthcoming_toc {
	FONT-SIZE: 85%;
	selector-dummy:
	expression(this.hideFocus=true);
	PADDING-TOP: 5px; PADDING-bottom: 2px;
	color: #777777;
}

.forthcoming_toc a {
	color: #777777;
	text-decoration: none;
}

.forthcoming_author {
	font-size: 95%;
	font-weight: normal;
	text-decoration: none;
	display:inline;
	color: #777777;
}

.forthcoming_aff {
	font-size: 95%;
	font-weight: normal;
	text-decoration: none;
	display:inline;
	color: #777777;
}

.forthcoming_abstract {
	color: #900000;
	text-decoration: underline;
	font-family: Verdana;
	font-size: 85%;
}

.Title_box {
	font-family:Verdana;
	COLOR: #ffffff;
	FONT-SIZE: 10pt;
}

.Article a {
	COLOR: #DE1434;
	selector-dummy:
	expression(this.hideFocus=true);
}


Table.copyright {
	FONT-SIZE: 80%;
	font-family: helvetica;
	display: inline;
	color: #a0a0a0;
	text-decoration: none;
	selector-dummy:
	expression(this.hideFocus=true);
}

.copyright a {
	text-decoration: none;
}

Table.Box {
width: 100%;
BORDER-BOTTOM: #430752 2px solid;
BORDER-LEFT: #430752 2px solid;
BORDER-TOP: #430752 2px solid;
BORDER-RIGHT: #430752 2px solid;
margin-bottom: 2em;
LINE-HEIGHT: 170%;
FONT-FAMILY: Arial;
COLOR: #000000;
FONT-SIZE: 80%;
TEXT-DECORATION: none;
}

Table.Box02 {
	font-family: Verdana;
	font-size: 8pt;
	line-height: 12pt;
	display:inline;
	color: #777777;
	text-decoration: none;
	border-top:2px solid #6e82b4;
	border-bottom:2px solid #6e82b4;
	border-left:2px solid #6e82b4;
	border-right:2px solid #6e82b4;
	padding-top:4px;padding-bottom:4px;padding-right:4px;padding-left:4px;
}


Table.box_citation {
	Text-Decoration: None;
	Border-Top:1Px Solid #9E9E9E;
	Border-Bottom:1Px Solid #9E9E9E;
	Border-Left:1Px Solid #9E9E9E;
	Border-Right:1Px Solid #9E9E9E;
}

Table.List {
	FONT-SIZE: 80%;
	font-family: Verdana;
	display: inline;
	color: #000000;
	text-decoration: none;
	line-height:160%;
	font-weight:normal;
}

.List a {
	color: #DE1434;
}
.List th {
     border-bottom:2px solid #F39700;
     border-top:2px solid #F39700;
     padding-top:4px;padding-bottom:4px;
}

.List td {
    vertical-align:top;
    border-bottom:1px solid #F39700;
}

.LineMap {
	COLOR: #600048;
	FONT-SIZE: 80%;
	font-family: Verdana;
	text-decoration: none;
}
.LineMap a {
	text-decoration: none;
	color: #600048;
}

.TableOfContentsHeader {
	color: #676767;
	FONT-SIZE: 12pt;
	font-family: Verdana;
	text-decoration: none;
}


.ToC_subjectArea {
	color: #ffffff;
	FONT-SIZE: 100%;
	font-family: arial;
	text-align:center ;
	font-weight:bold;
	text-decoration: none;
	background-color:#d7000f;
    padding-top:4px;padding-bottom:4px;
}

.ToC_subject {
	color: #ffffff;
	FONT-SIZE: 90%;
	font-family: arial;
	text-align:center;
	font-weight:bold;
	text-decoration: none;
	background-color:#d7000f;
    padding-top:4px;padding-bottom:4px;
}


.author-email {
	color: gray;
  }
    
.author-email a {
	color: #EB6100;
	}
	    
.citation-comment {
	font-size: 90%;
    }
    
.citation-comment a {
	font-size: 90%;
    }
	
/* Added 2012-12-19 */

.article-retracted {
 BORDER : #7d0000 1px solid; 
 TEXT-ALIGN: center; 
 MARGIN-RIGHT: 0.5em;
 BACKGROUND-COLOR: #fffcd9; 
 PADDING: 10px;
 MARGIN-BOTTOM: 1.5em; 
 box-shadow: 0.4em 0.4em 0.5em rgba(0,0,0,.3);
}

.article-retracted A {
 FONT-FAMILY: Verdana; COLOR: #7d0000;
 font-size: 1.1em; text-align: center;
 font-weight: lighter;
 line-height: 1.5;
 text-decoration: underline;
}

.article-doctype {
	TEXT-ALIGN: left; FONT-FAMILY: verdana; FLOAT: left; COLOR: #898989; FONT-SIZE: 10pt; FONT-WEIGHT: bold;
}
.article-openaccess {
	TEXT-ALIGN: right; FONT-FAMILY: verdana; FLOAT: right; COLOR: #f18101; FONT-SIZE: 10pt; FONT-WEIGHT: bold;
}
HR.article-doctype-openaccess-underbar {
	FLOAT: TOP; WIDTH: 100%; HEIGHT: 1px; COLOR: #f18101; align: center
}


	
/* Added 2012-12-21 */

.toc-openaccess {
	color: #f18101;	
}


	
/* Added 2012-12-25 */

HR.article-menubar-top {
	FLOAT: TOP; WIDTH: 100%; HEIGHT: 1px; align: center; COLOR: #D7000F;
}

HR.article-menubar-bottom {
	FLOAT: TOP; WIDTH: 100%; HEIGHT: 2px; align: center; COLOR: #D7000F;
}


.ORCID a {
	COLOR: #000000;
	TEXT-DECORATION: none;
	BORDER-BOTTOM: black 1px dotted;
	}



.MeSHMark div {
	vertical-align:top;
	padding:0px;
	margin-top:0px;
	height:16px;
	max-width: 180px;
	white-space: nowrap;
	overflow: hidden;
	display: inline-block;
}

.MeSHMark img {
	vertical-align:middle;
	border:0;
}


.ExternalLinkFT a
{
	TEXT-DECORATION: none;
	BORDER-BOTTOM: black 1px dotted;
	COLOR: #000000;
}

.ExternalLinkFT img
{
	border: 0;
	vertical-align: top;
	margin-right: 0.15em;
}

.ExternalLinkFT
{
	font-size:0.9em;
}

.ExternalViewTable
{
	border-top: 2px solid black;
	border-bottom: 1px solid black;
}

.ExternalViewTable th
{
    background-color: #dedede;
    border-top: 0px solid #dedede;
    border-bottom: 1px solid #000000;
    padding-left: 0.5em;
    padding-right: 0.5em;
}

.ExternalViewTable	td
{
	border-top: 1px solid #dedede;
	border-bottom: 0px solid #dedede;
	padding-left: 0.5em;
	padding-right: 0.5em;
}


.citation-comment 
{
	FONT-SIZE: 90%;
	overflow-wrap: break-word;
	word-wrap: break-word;
	-ms-word-break: break-all;
	word-break: break-all;
	word-break: break-word;
	-ms-hyphens: auto;
	-moz-hyphens: auto;
	-webkit-hyphens: auto;
	hyphens: auto;
}


.bm .listitem p 
{
	margin: 0px;
	padding: 0px;
}


.MeSHMark-wrap div {
	display:inline-block;		
}

.MeSHMark-wrap	.terms {
	vertical-align:middle; 
	float:left; 
	width: 183px; 
	overflow: visible; 
	word-wrap: break-word;		
	text-indent: -0.5em;
	padding-left: 0.5em;
}

.MeSHMark-wrap .pin {
	float:right; 
	vertical-align:middle; 		
}

.MeSHMark-wrap img {
	padding-top:5px;
	vertical-align:middle;
	border:0;
}