Author's Reply to Case report on combining PRF with alloplastic bone substitute in Endo-Perio lesion

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Restor Dent Endod. 2021;46.e45

Publication date (electronic) : 2021 August 11

doi : https://doi.org/10.5395/rde.2021.46.e45

Department of Periodontics and Community Dentistry, Dr. Ziauddin Ahmad Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Correspondence to Lata Goyal, MDS. Ex Resident, Department of Periodontics and Community Dentistry, Dr. Ziauddin Ahmad Dental College, Aligarh Muslim University, University Road, Zakaullah Rd, Medical Colony, Aligarh, Uttar Pradesh 202002, India. latagoyal83@gmail.com

Received 2021 March 20; Accepted 2021 May 10.

I thank the readers for finding this case report interesting and raising the issue regarding the terminology used. Platelet rich plasma (PRP) was activated with calcium chloride and hence coagulated PRP term has been used here. Fibrin matrix which is achieved with the use of PRP and exogenous activators has been given different terminology in the literature like platelet rich fibrin (PRF) matrix, PRF, platelet gel, PRF clot, PRP gel [1 2 3]. I agree with the readers that PRF is a widely accepted term for preparation with a natural coagulation pathway earlier known as Choukron's PRF. Hence PRP/PRF gel may be a better alternative term for the preparation as in the present case report. In the past two decades, this area has gone a lot of innovations and modifications [4]. PRF is a broad term that is used for various preparations, protocols and various variables affecting its composition. As there is a lot of heterogeneity regarding the terminology used, to better compare the results and drawing an inference, these terms may be correlated with the methodology used. I am thankful for giving me the opportunity to clarify my intent in this case report.

Notes

Conflict of Interest: No potential conflict of interest relevant to this article was reported.

References

1. Yang LC, Hu SW, Yan M, Yang JJ, Tsou SH, Lin YY. Antimicrobial activity of platelet-rich plasma and other plasma preparations against periodontal pathogens. J Periodontol 2015;86:310–318. 25345340.

2. Peck MT, Hiss D, Stephen L, Satti A, Majeed A. Platelet- rich fibrin (PRF) - the effect of storage time on platelet concentration. S Afr Dent J 2015;70:448–451.

3. Isobe K, Suzuki M, Watanabe T, Kitamura Y, Suzuki T, Kawabata H, Nakamura M, Okudera T, Okudera H, Uematsu K, Nakata K, Tanaka T, Kawase T. Platelet-rich fibrin prepared from stored whole-blood samples. Int J Implant Dent 2017;3:6. 28251561.

4. Nishimoto S, Fujita K, Fujiwara T, Sotsuka Y, Tonooka M, Ishise H, Kawai K, Kakibuchi M. An attempt to make platelet rich fibrin from bone marrow aspirate. J Clin Diagn Res 2017;11:PC04–PC07.

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The Korean Academy of Conservative Dentistry

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