Pulp tissue regeneration and root formation of permanent teeth with pulpal/periapical deseases

Article information

Restor Dent Endod. 2010;35(4):238-245

Publication date (electronic) : 2010 July 31

doi : https://doi.org/10.5395/JKACD.2010.35.4.238

Yeon-Jee Yoo , Seung-Ho Baek , Ho-Hyun Son

Department of Conservative Dentistry, School of Dentistry, Seoul National University, Seoul, Korea.

Corresponding Author: Ho-Hyun Son. Department of Conservative Dentistry and Dental Research, Institute, School of Dentistry, Seoul National University, 28-2 Yeongeon-Dong, Jongro-Gu, Seoul, 110-749, Korea. Tel: +82-2-2072-2652 Fax: +82-2-2072-3859, hhson@snu.ac.kr

Received 2010 June 23; Revised 2010 June 28; Accepted 2010 June 30.

Abstract

Numerous cases about additional growth of roots or pulp tissue regeneration by using various intracanal medicaments in immature permanent teeth with periapical or pulpal disease have been reported. The underlying mechanism has not been clearly delineated, but it has been widely accepted that undifferentiated mesenchymal cells and stem cells are involved. Moreover, the growth and deposition of osteoid or cementoid tissues have been observed in regenerated pulp and roots. This new and non-invasive treatment has brightened the future of endodontics, and enlarged the vision of regenerative root canal treatment with multi-potent stem cells and various tissue engineering techniques.

Keywords: Revascularization; Pulp tissue regeneration; Root formation; Tri-antibiotic paste; Tissue engineering

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