Effect of local anesthesia on pulpal blood flow in mechanically stimulated teeth

Article information

Restor Dent Endod. 2006;31(4):257-262

Publication date (electronic) : 2006 January 14

doi : https://doi.org/10.5395/JKACD.2006.31.4.257

Wan-Sik Chu , Seung-Ho Park , Dong-Kuk Ahn ¹, Sung Kyo Kim ^,

Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea

¹Department of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu, Korea

^*Corresponding Author: Sung Kyo Kim, Department of Conservative Dentistry, School of Dentistry, Kyungpook National University 188-1, Samdeok-Dong, 2-Ga, Jung-Gu, Daegu, Korea, 700-412, Tel: 82-53-420-5935 Fax: 82-53-426-8958, E-mail: skykim@knu.ac.kr

Received 2005 August 23; Revised 2006 January 24; Accepted 2006 February 09.

Abstract

The aims of the study were to evaluate the effect of epinephrine-containing local anesthetics on pulpal blood flow (PBF) and to investigate its effect on cavity preparation-induced PBF change. PBF was recorded using a laser Doppler flowmeter (Perimed Co., Sweden) from canines of nine cats under general anesthesia before and after injection of local anesthetics and after cavity preparation. 2% lidocaine hydrochloride with 1 : 100,000 epinephrine was administered by local infiltration given apical to the mandibular canine at the vestibular area and the same volume of isotonic saline was injected on the contralateral tooth as a control. A round carbide bur was operated at slow speed with isotonic saline flushing to grind spherical cavities with increasing depth through the enamel and into the dentin on both teeth. The obtained data was analyzed with paired t-test.

Cavity preparation caused significant increase of PBF (n = 9, p < 0.05). Local infiltration of lidocaine with epinephrine resulted in decreases of PBF (n = 9, p < 0.05), whereas there was no significant change of PBF with the physiologic saline as a control. Cavity preparation on tooth anesthetized with lidocaine with epinephrine caused significantly less increase of PBF than in control tooth (p < 0.05).

Therefore, the result of the present study demonstrates that local infiltration of 2% lidocaine with 1 : 100,000 epinephrine effectively reduces PBF increase caused by cavity preparation.

Keywords: Pulpal blood flow; Epinephrine; Lidocaine; Cavity preparation; Local anesthetics; Neurogenic inflammation

Figure 1.

Schematic drawing of devices used to record pulpal blood flow.

Figure 2.

Changes in pulpal blood flow in response to the cavity preparation.

Figure 3.

Changes in pulpal blood flow PBF in response to local infiltration of 2% lidocaine with 1 : 100,000 epinephrine (mean ± SEM).

Figure 4.

Changes in pulpal blood flow PBF in response to cavity preparation (mean ± SEM).

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